keyword
https://read.qxmd.com/read/38537209/enchondroma-on-bone-scan-and-psma-pet-ct-in-a-patient-with-prostate-cancer
#1
JOURNAL ARTICLE
Charisma DeSai, Lesley Flynt, Sanjit Om Tewari, Yang Lu
A 54-year-old man with Gleason 9 prostate cancer with reported nodal and skeletal metastases was referred to us. Outside hospital reports described abnormal left proximal humerus activity on bone scan concerning for metastasis; however, concurrent PSMA PET/CT did not show activity in this lesion. Further review of the PET/CT images revealed characteristic features of enchondroma in the left humeral lesion.
March 25, 2024: Clinical Nuclear Medicine
https://read.qxmd.com/read/38535060/nodal-low-grade-b-cell-lymphoma-co-expressing-cd5-and-cd10-but-not-cd23-irta1-or-cyclin-d1-the-diagnostic-challenge-of-a-splenic-marginal-zone-lymphoma
#2
JOURNAL ARTICLE
Khin-Than Win, Yen-Chuan Hsieh, Hung-Chang Wu, Shih-Sung Chuang
The diagnosis of lymphoma is based on histopathological and immunophenotypical features. CD5 and CD10 are traditionally considered a T-cell antigen and a germinal center B-cell antigen, respectively. It is very unusual for a low-grade B-cell lymphoma (BCL) to co-express CD5 and CD10. Although the biologic basis or clinical significance of such co-expression is unclear, this rare event may pose a significant diagnostic challenge. Here, we report a case of a 63-year-old male presenting with bilateral cervical lymphadenopathy and lymphocytosis...
March 18, 2024: Diagnostics
https://read.qxmd.com/read/38534923/the-role-of-adjuvant-radiotherapy-in-the-treatment-of-breast-cancer
#3
REVIEW
Iveta Kolářová, Bohuslav Melichar, Igor Sirák, Jaroslav Vaňásek, Jiří Petera, Kateřina Horáčková, Denisa Pohanková, Filip Ďatelinka, Zuzana Šinkorová, Milan Vošmik
The role of postmastectomy radiotherapy and regional nodal irradiation after radical mastectomy is defined in high-risk patients with locally advanced tumors, positive margins, and unfavorable biology. The benefit of postmastectomy radiotherapy in intermediate-risk patients (T3N0 tumors) remains a matter of controversy. It has been demonstrated that radiotherapy after breast-conserving surgery lowers the locoregional recurrence rate compared with surgery alone and improves the overall survival rate. In patients with four or more positive lymph nodes or extracapsular extension, regional lymph node irradiation is indicated regardless of the surgery type (breast-conserving surgery or mastectomy)...
February 24, 2024: Current Oncology
https://read.qxmd.com/read/38534852/distributed-state-estimation-for-flapping-wing-micro-air-vehicles-with-information-fusion-correction
#4
JOURNAL ARTICLE
Xianglin Zhang, Mingqiang Luo, Simeng Guo, Zhiyang Cui
In this paper, we explore a nonlinear interactive network system comprising nodalized flapping-wing micro air vehicles (FMAVs) to address the distributed H∞ state estimation problem associated with FMAVs. We enhance the model by introducing an information fusion function, leading to an information-fusionized estimator model. This model ensures both estimation accuracy and the completeness of FMAV topological information within a unified framework. To facilitate the analysis, each FMAV's received signal is individually sampled using independent and time-varying samplers...
March 10, 2024: Biomimetics
https://read.qxmd.com/read/38534782/clinical-genomic-analysis-of-1261-patients-with-ehlers-danlos-syndrome-outlines-an-articulo-autonomic-gene-network-entome
#5
JOURNAL ARTICLE
Golder N Wilson, Vijay S Tonk
Systematic evaluation of 80 history and 40 history findings diagnosed 1261 patients with Ehlers-Danlos syndrome (EDS) by direct or online interaction, and 60 key findings were selected for their relation to clinical mechanisms and/or management. Genomic testing results in 566 of these patients supported EDS relevance by their differences from those in 82 developmental disability patients and by their association with general rather than type-specific EDS findings. The 437 nuclear and 79 mitochondrial DNA changes included 71 impacting joint matrix (49 COL5 ), 39 bone (30 COL1/2/9/11 ), 22 vessel (12 COL3/8VWF) , 43 vessel-heart (17 FBN1 /11 TGFB / BR) , 59 muscle (28 COL6/12 ), 56 neural (16 SCN9A / 10A / 11A ), and 74 autonomic (13 POLG /25porphyria related)...
March 19, 2024: Current Issues in Molecular Biology
https://read.qxmd.com/read/38532619/chemical-bonding-and-the-role-of-node-induced-electron-confinement
#6
JOURNAL ARTICLE
Alistair J Sterling, Daniel S Levine, Abdulrahman Aldossary, Martin Head-Gordon
The chemical bond is the cornerstone of chemistry, providing a conceptual framework to understand and predict the behavior of molecules in complex systems. However, the fundamental origin of chemical bonding remains controversial and has been responsible for fierce debate over the past century. Here, we present a unified theory of bonding, using a separation of electron delocalization effects from orbital relaxation to identify three mechanisms [node-induced confinement (typically associated with Pauli repulsion, though more general), orbital contraction, and polarization] that each modulate kinetic energy during bond formation...
March 26, 2024: Journal of the American Chemical Society
https://read.qxmd.com/read/38532076/follicular-dendritic-cell-sarcoma-arising-from-the-lymph-node-of-the-pancreatic-head-a-case-report-with-literature-review
#7
JOURNAL ARTICLE
Takahiro Yamada, Keinosuke Ishido, Norihisa Kimura, Taiichi Wakiya, Hayato Nagase, Shintaro Goto, Tadashi Yoshizawa, Hiroshi Kijima, Seiichi Kato, Kenichi Hakamada
A 72-year-old man was referred to our hospital for the examination of a pancreatic head mass. Abdominal computed tomography revealed a contrasted 8-cm-diameter tumor extending from the dorsal pancreatic head to the porta hepatis. The preoperative diagnosis was challenging due to the absence of specific imaging findings and the inability to perform a biopsy. Positron emission tomography/computed tomography and diffusion-weighted imaging suggested a malignant tumor originating from the organs surrounding the pancreatic head...
March 26, 2024: Clinical Journal of Gastroenterology
https://read.qxmd.com/read/38530980/intraoperative-immunohistochemistry-during-mohs-micrographic-surgery-and-staged-excision-decreases-local-recurrence-rates-for-invasive-cutaneous-melanoma-a-systematic-review-and-meta-analysis
#8
JOURNAL ARTICLE
Keegan O'Hern, Olivia M Crum, Addison M Demer, Jerry D Brewer
BACKGROUND: Mohs micrographic surgery (MMS) is increasingly used to treat cutaneous melanoma. However, it is unclear whether intraoperative immunohistochemistry (IHC) improves surgical outcomes. OBJECTIVE: To determine whether intraoperative IHC during MMS and staged excision is associated with a decreased risk of poor surgical outcomes. MATERIALS AND METHODS: Search of 6 databases identified comparative and noncomparative studies that reported local recurrence after MMS or staged excision with or without IHC for melanoma...
March 26, 2024: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://read.qxmd.com/read/38529341/extranodal-extension-in-laryngeal-squamous-cell-carcinoma
#9
JOURNAL ARTICLE
Aman M Patel, Sudeepti Vedula, Ariana L Shaari, Hannaan S Choudhry, Andrey Filimonov
OBJECTIVE: Although large retrospective database studies have associated extranodal extension (ENE) with worse survival in several head and neck cancers, the prognostic significance of ENE in laryngeal squamous cell carcinoma (LSCC) remains unclear. Our study examines ENE and overall survival (OS) in LSCC. METHODS: The 2006-2017 National Cancer Database was queried for patients with LSCC undergoing surgical resection and neck dissection, with or without adjuvant therapy...
April 2024: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/38529058/genetic-gains-in-forage-sorghum-for-adaptive-traits-for-non-conventional-area-through-multi-trait-based-stability-selection-methods
#10
JOURNAL ARTICLE
Partha Pratim Behera, Avinash Singode, B Venkatesh Bhat, Venkateswarlu Ronda, Nayanmoni Borah, Harendra Verma, Labhya Rani Gogoi, Jyoti Lekha Borah, Prasanta Kumar Majhi, Niharika Saharia, Ramendra Nath Sarma
INTRODUCTION: In the Asian tropics, unpredictable weather increases the risk of abiotic stresses in sorghum areas, making it harder to meet predicted demand. Genotype-by environment interaction (GEI) and the lack of an effective multi-trait-based selection approach make it challenging to breed climateresilient forage sorghum that adapts to nonconventional areas. METHODS: The present investigation carried out to estimate genetic parameters, inter trait associations, genetic gain under selection (SGs) of 95 diverse forage sorghum genotypes...
2024: Frontiers in Plant Science
https://read.qxmd.com/read/38528949/stridor-caused-by-endobronchial-lymphoma-in-a-middle-aged-woman
#11
Chih-Hsi Pan, Chien-Wen Chen
Diffuse large B-cell lymphoma, primarily nodal in nature, can present with rare endobronchial involvement, underscoring the importance of considering it in the differential diagnoses of endobronchial lesions.
March 2024: Respirology Case Reports
https://read.qxmd.com/read/38528726/papillary-thyroid-carcinoma-tall-cell-subtype-ptc-tc-and-high-grade-differentiated-thyroid-carcinoma-tall-cell-phenotype-hgdtc-tc-have-different-clinical-behaviour-a%C3%A2-retrospective-study-of-1456-patients
#12
JOURNAL ARTICLE
Ronald Ghossein, Nora Katabi, Snjezana Dogan, Ashok R Shaha, R Michael Tuttle, James A Fagin, Ian Ganly, Bin Xu
AIMS: Papillary thyroid carcinoma, tall cell subtype (PTC-TC) is a potentially aggressive histotype. The latest World Health Organisation (WHO) classification introduced a novel class of tumours; namely, high-grade differentiated thyroid carcinoma (HGDTC), characterised by elevated mitotic count and/or necrosis, which can exhibit a tall cell phenotype (HGDTC-TC). METHODS AND RESULTS: We analysed the clinical outcomes in a large retrospective cohort of 1456 consecutive thyroid carcinomas with a tall cell phenotype, including PTC-TC and HGDTC-TC...
March 25, 2024: Histopathology
https://read.qxmd.com/read/38528444/adjuvant-chemotherapy-and-survival-in-males-aged-70-years-or-older-with-breast-cancer-a-population-based-retrospective-study
#13
JOURNAL ARTICLE
Yushuai Yu, Kaiyan Huang, Yushan Liu, Ruiliang Chen, Xin Yu, Chuangui Song
BACKGROUND: Male breast cancer constitutes a minority of breast cancer diagnoses, yet its incidence has been on the rise in recent decades. However, elderly male breast cancer patients have been inadequately represented in clinical trials, posing challenges in treatment decisions. This study seeks to clarify the efficacy of chemotherapy in this demographic and identify the population most likely to benefit from such intervention. METHODS: We conducted a retrospective analysis using the Surveillance, Epidemiology, and End Results (SEER) database, encompassing a total of 1900 male breast cancer patients aged 70 years or older...
March 25, 2024: BMC Geriatrics
https://read.qxmd.com/read/38528294/pd-l1-expression-and-microsatellite-instability-msi-in-cancer-of-unknown-primary-site
#14
JOURNAL ARTICLE
João Neif Antonio Junior, Daniel D 'Almeida Preto, Maria Eduarda Zanatta Neder Lazarini, Marcos Alves de Lima, Murilo Bonatelli, Gustavo Noriz Berardinelli, Vinicius Duval da Silva, Céline Pinheiro, Rui Manuel Reis, Flavio Mavignier Cárcano
BACKGROUND: Cancer of unknown primary site (CUP) is a heterogeneous group of tumors for which the origin remains unknown. Clinical outcomes might be influenced by regulatory processes in its microenvironment. Microsatellite instability (MSI) is a predictive biomarker for cancer immunotherapy and its status, as well as co-occurrence with PD-L1 expression, is poorly evaluated. We aim to evaluate the expression of PD-L1 and the status of MSI in CUP and their possible associations with clinical-pathological features...
March 25, 2024: International Journal of Clinical Oncology
https://read.qxmd.com/read/38527730/controversia-en-la-estadificaci%C3%A3-n-inicial-ganglionar-en-el-ca-de-recto-%C3%A2-rm-o-pet-tc
#15
JOURNAL ARTICLE
Elena López Llobet, Mónica Coronado Poggio, Carmen Lancha Hernández, Carmen Martín Hervás, Daniela Travaglio Morales, Doménico Monachello Araujo, Sonia Rodado Marina, Luís Domínguez Gadea
OBJECTIVE: To compare the usefulness of MRI and PET/CT in nodal staging (N) of patients with locally advanced rectal cancer (LARC). MATERIAL AND METHODS: Retrospective study of patients with LARC, who completed their initial staging with PET/CT, between January-20 and March-23. Regional nodes were assessed, and N was determined using both techniques according to TNM criteria. Concordance between MRI and PET/CT was analyzed. The accuracy of both techniques was calculated for those patients who underwent direct surgery...
March 23, 2024: Revista española de medicina nuclear e imagen molecular
https://read.qxmd.com/read/38527594/tertiary-prevention-strategies-for-micrometastatic-lymph-node-cervical-cancer-a-systematic-review-and-a-prototype-of-an-adapted-model-of-care
#16
REVIEW
Marcin Śniadecki, Benedetta Guani, Paulina Jaworek, Dagmara Klasa-Mazurkiewicz, Katia Mahiou, Karolina Mosakowska, Alessandro Buda, Patryk Poniewierza, Olga Piątek, Adrien Crestani, Maria Stasiak, Vincent Balaya, Oliwia Musielak, Luiza Piłat, Karolina Maliszewska, Cynthia Aristei, Paweł Guzik, Szymon Wojtylak, Marcin Liro, Thomas Gaillard, Roman Kocian, Anna Gołąbiewska, Zuzanna Chmielewska, Dariusz Wydra
PURPOSE: We found a need for balancing the application of clinical guidelines and tailored approaches to follow-up of cervical cancer (CC) patients in the lymph node micrometastatic (MICs) setting. This review aimed to determine the current knowledge of management of MIC-positive CC cases. METHODOLOGY: We addressed prognostic and risk of recurrence monitoring impacts associated with MIC+ cases. The electronic databases for literature and relevant articles were analysed...
March 23, 2024: Critical Reviews in Oncology/hematology
https://read.qxmd.com/read/38527388/prognostic-relevance-of-the-most-predominant-and-least-differentiated-grades-of-gastric-adenocarcinoma-after-curative-gastrectomy
#17
JOURNAL ARTICLE
Yasuo Imai, Yoshihiro Kurata, Masanori Ichinose
BACKGROUND: Prognostic relevance of differentiation grade has remained controversial in gastric adenocarcinoma (GAC) after curative resection. METHODS: GAC patients who underwent curative gastrectomy were analyzed. Differentiation grade was evaluated according to either the most predominant or least differentiated component. Impacts of clinicopathologic parameters on postoperative recurrence and nodal metastasis were analyzed by the multivariate Cox regression analysis in pT1/2/3/4a and pT1b/2/3 GAC and by the logistic regression analysis in pT1b GAC, respectively...
March 20, 2024: Surgical Oncology
https://read.qxmd.com/read/38526949/corpus-callosum-and-cerebellum-participate-in-semantic-dysfunction-of-parkinson-s-disease-a-diffusion-tensor-imaging-based-cross-sectional-study
#18
JOURNAL ARTICLE
Hang Liu, Yuke Zhong, Guohui Liu, Huahua Su, Zhihui Liu, Jiahao Wei, Lijuan Mo, Changhong Tan, Xi Liu, Lifen Chen
Language dysfunction is common in Parkinson's disease (PD) patients, among which, the decline of semantic fluency is usually observed. This study aims to explore the relationship between white matter (WM) alterations and semantic fluency changes in PD patients. 127 PD patients from the Parkinson's Progression Markers Initiative cohort who received diffusion tensor imaging scanning, clinical assessment and semantic fluency test (SFT) were included. Tract-based special statistics, automated fiber quantification, graph-theoretical and network-based analyses were performed to analyze the correlation between WM structural changes, brain network features and semantic fluency in PD patients...
March 11, 2024: Neuroreport
https://read.qxmd.com/read/38525121/a-22-year-single-institution-review-of-119-cases-of-salivary-duct-carcinoma
#19
JOURNAL ARTICLE
Ethan J Han, Laith A Mukdad, Yazeed Alhiyari, Morcos N Nakhla, Dipti P Sajed, Maie A St John
OBJECTIVE: Salivary duct carcinoma (SDC) is a rare and aggressive salivary gland malignancy. Herein, we present the largest single-institution review of SDC to date. METHODS: This is a retrospective cohort study of all histologically confirmed cases of SDC seen at our institution from January 1, 2002, to August 1, 2022. Patient demographics, treatment, histological characteristics, tumor staging, and outcomes were extracted from the electronic medical record. Kaplan-Meier and Cox regression survival analyses were performed...
April 2024: Laryngoscope Investigative Otolaryngology
https://read.qxmd.com/read/38524944/national-drug-laws-policies-and-programs-in-india-a-narrative-review
#20
REVIEW
Arpit Parmar, Venkata Lakshmi Narasimha, Santanu Nath
BACKGROUND: Drug use is a major public health issue in India. Significant changes in the approach toward drug use have happened in the last few decades. Despite this, no systematic attempt has been made to document the same in the scientific literature. This narrative review attempts to discuss the major drug laws, policies, and national programs of the Government of India (GoI). METHODS: A thorough search was conducted to look for policies, programs, acts, and notifications related to substance use/drug use on various websites of different ministries of the GoI...
January 2024: Indian Journal of Psychological Medicine
keyword
keyword
118755
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.