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berberis vulgaris

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https://www.readbyqxmd.com/read/27876206/synergistic-anti-cancer-effects-of-galangin-and-berberine-through-apoptosis-induction-and-proliferation-inhibition-in-oesophageal-carcinoma-cells
#1
Kewei Ren, Wenzhe Zhang, Gang Wu, Jianzhuang Ren, Huibin Lu, Zongming Li, Xinwei Han
Galangin is an active pharmacological ingredient from propolis and Alpinia officinarum Hance, and has been reported to have anti-cancer and antioxidative properties. Berberine, a major component of Berberis vulgaris extract, exhibits potent anti-cancer activities through distinct molecular mechanisms. However, the anticancer effect of galangin in combination with berberine is still unknown. In the present study, we demonstrated that the combination of galangin with berberine synergistically resulted in cell growth inhibition, apoptosis and cell cycle arrest at G2/M phase with the increased intracellular reactive oxygen species (ROS) levels in oesophageal carcinoma cells...
November 18, 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27794507/-a-novel-survey-of-the-ethno-medicinal-knowledge-of-dental-problems-in-manoor-valley-northern-himalaya-pakistan
#2
Inayat Ur Rahman, Farhana Ijaz, Zafar Iqbal, Aftab Afzal, Niaz Ali, Muhammad Afzal, Muhammad Azhar Khan, Said Muhammad, Ghulam Qadir, Muhammad Asif
ETHNOPHARMACOLOGICAL RELEVANCE: In the study area, the traditional knowledge and cultural practices of utilizing medicinal plants in the human healthcare is primarily restricted to the old age members of the community, while younger generation is mostly unaware of the natural wealth usage. AIM OF THE STUDY: We provide the first ever ethno medicinal insights into the management of dental disorders in Pakistan. The prime objective of the study was to explore novel knowledge of these local and remote community members and share it with rest of the world in documented form...
October 26, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27757195/comparison-between-the-efficacy-of-metronidazole-vaginal-gel-and-berberis-vulgaris-berberis-vulgaris-combined-with-metronidazole-gel-alone-in-the-treatment-of-bacterial-vaginosis
#3
Mansoure Masoudi, Mahmoud Rafieian Kopaei, Sepideh Miraj
BACKGROUND: Bacterial vaginosis is one of the most prevalent complications among reproductive-aged women. Antibacterial and antifungal effects of Berberis vulgaris have been demonstrated in vitro and in vivo. OBJECTIVES: This study aimed to compare the therapeutic effects of the vaginal gel of Berberis vulgaris 5% (in metronidazole base) with metronidazole vaginal gel 0.75% on bacterial vaginosis on 80 patients referred to the Hajar Hospital from January 2012 to April 2013...
August 2016: Electronic Physician
https://www.readbyqxmd.com/read/27689107/an-ethnobotanical-study-of-medicinal-plants-administered-for-the-treatment-of-hypertension
#4
Babak Baharvand-Ahmadi, Mahmoud Bahmani, Pegah Tajeddini, Mahmoud Rafieian-Kopaei, Nasrollah Naghdi
INTRODUCTION: The incidence of cardiovascular diseases (CVDs) is very high in human societies and their prevention and treatment are the most important priority in many countries. Hypertension makes an important contribution to the development of CVDs. OBJECTIVES: This study aimed to collect the ethno-medicinal knowledge of the traditional healers of Shiraz on medicinal plants used in the treatment of hypertension. MATERIALS AND METHODS: Ethno-medicinal data were collected from September 2012 to July 2013 through direct interview...
2016: Journal of Renal Injury Prevention
https://www.readbyqxmd.com/read/27671811/berberine-and-its-role-in-chronic-disease
#5
Arrigo F G Cicero, Alessandra Baggioni
Berberine is a quaternary ammonium salt from the protoberberine group of isoquinoline alkaloids. It is found in such plants as Berberis [e.g. Berberis aquifolium (Oregon grape), Berberis vulgaris (barberry), Berberis aristata (tree turmeric)], Hydrastis canadensis (goldenseal), Xanthorhiza simplicissima (yellowroot), Phellodendron amurense ([2]) (Amur corktree), Coptis chinensis (Chinese goldthread), Tinospora cordifolia, Argemone mexicana (prickly poppy) and Eschscholzia californica (Californian poppy). In vitro it exerts significant anti-inflammatory and antioxidant activities...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27577059/investigation-of-the-immunomodulatory-effect-of-berberis-vulgaris-on-core-pulsed-dendritic-cell-vaccine
#6
Doaa A Ghareeb, Eiman H Elwakeel, Rowaida Khalil, Mina S Aziz, Maha A El Demellawy
BACKGROUND: Virus-induced dendritic cells (DCs) functional deficiency leads to sub-optimal initiation of adaptive immune responses and consequently chronic infection establishment. The present study reports an advanced hepatitis C virus (HCV) therapeutic vaccine model based on In vivo enrichment of DCs with barberry ethanolic crude extract (BCE) then pulsing them with HCV core protein. METHODS: DCs were enriched by BCE intravenous injection in BALB/c mice. Vaccine efficiency was assessed by flow cytometric analysis of splenocytes of immunized mice, cytokine profiling, cytotoxic T lymphocyte assay, and humoral immune response assessment...
2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27528198/berberis-vulgaris-and-berberine-an-update-review
#7
Mohsen Imenshahidi, Hossein Hosseinzadeh
Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and Berberis sp. Berberine is a customary component in Chinese medicine, and is characterized by a diversity of pharmacological effects. An extensive search in electronic databases (PubMed, Scopus, Ovid, Wiley, ProQuest, ISI, and Science Direct) were used to identify the pharmacological and clinical studies on Berberis vulgaris and berberine, during 2008 to 2015, using 'berberine' and 'Berberis vulgaris' as search words. We found more than 1200 new article studying the properties and clinical uses of berberine and B...
August 16, 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/27426508/pharmacological-safety-evaluation-of-a-traditional-herbal-medicine-zereshk-e-saghir-and-assessment-of-its-hepatoprotective-effects-on-carbon-tetrachloride-induced-hepatic-damage-in-rats
#8
Zarrin Sarhadynejad, Fariba Sharififar, Abbas Pardakhty, Mohammad-Hadi Nematollahi, Saeedeh Sattaie-Mokhtari, Ali Mandegary
ETHNOPHARMACOLOGICAL RELEVANCE: "Zereshk-e-Saghir" (ZES), one of the traditional herbal medicines in old manuscripts of Persian hakims, has been used for the treatment of liver disorders. This current study is aimed to evaluate ZES effects on animal model to investigate its safety and hepatoprotective activity. MATERIALS AND METHODS: ZES was prepared according to a traditional method by blending aqueous extracts of Berberis vulgaris L., with fine particles of other plants including Rosa damascene Mill, Cichorium intybus L...
August 22, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27261610/protective-effect-of-berberis-vulgaris-fruit-extract-against-paraquat-induced-pulmonary-fibrosis-in-rats
#9
Seyed Ali Javad-Mousavi, Ali Asghar Hemmati, Saeed Mehrzadi, Azam Hosseinzadeh, Gholamreza Houshmand, Mohammad Reza Rashidi Nooshabadi, Mehrnaz Mehrabani, Mehdi Goudarzi
BACKGROUND: Pulmonary fibrosis induced by paraquat (PQ) has caused a large number of human fatalities all over the world, especially in Asian region. The main potential mechanism of PQ toxicity has been thought to be mediated by ROS. The present study was designed to evaluate the efficacy of the Berberis vulgaris fruit extract (BVFE) against PQ-induced pulmonary fibrosis in rats. METHODS: Forty male rats were randomly divided into five experimental groups each containing eight rats...
July 2016: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/27222833/effects-of-berberine-on-acquisition-and-reinstatement-of-morphine-induced-conditioned-place-preference-in-mice
#10
Faezeh Vahdati Hassani, Mahmoud Hashemzaei, Edris Akbari, Mohsen Imenshahidi, Hossein Hosseinzadeh
OBJECTIVE: It has been shown that berberine, a major component of Berberis vulgaris extract, modulates the activity of several neurotransmitter systems including dopamine (Da) and N-methyl-D-aspartate (NMDA) contributing to rewarding and reinforcing effects of morphine. Drug craving and relapsing even after a long time of abstinence therapy are the most important problems of addiction. In the present study, we investigated the alleviating effects of berberine on the acquisition and reinstatement of morphine-induced conditioned place preference (CPP) in mice...
March 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27134945/comparison-of-the-effects-of-myrtus-communis-l-berberis-vulgaris-and-metronidazole-vaginal-gel-alone-for-the-treatment-of-bacterial-vaginosis
#11
Mansoureh Masoudi, Sepideh Miraj, Mahmoud Rafieian-Kopaei
INTRODUCTION: There is a growing tendency towards herbal medicines for treatment of vaginitis. Antibacterial and antifungal effects of Myrtus communis L and Berberis vulgaris have been demonstrated invitro and invivo. AIM: This study aimed to compare the therapeutic effects of the vaginal gel of Berberis vulgaris 5% (in metronidazole base) and Myrtus communis L 2% (in metronidazole base) with only metronidazole vaginal gel 0.75% on bacterial vaginosis. MATERIALS AND METHODS: This study was a randomized clinical trial research on 120 married women aged 18-40 years affected by bacterial vaginosis attended for treatment to gynaecology clinic of Hajar Hospital (Shahrekord, Iran)...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27073630/sensitization-of-candida-albicans-to-terbinafine-by-berberine-and-berberrubine
#12
Pikling Lam, Stanton Hon Lung Kok, Kenneth Ka Ho Lee, Kim Hung Lam, Desmond Kwok Po Hau, Wai Yeung Wong, Zhaoxiang Bian, Roberto Gambari, Chung Hin Chui
Candida albicans (C. albicans) is an opportunistic fungal pathogen, particularly observed in immunocompromised patients. C. albicans accounts for 50-70% of cases of invasive candidiasis in the majority of clinical settings. Terbinafine, an allylamine antifungal drug, has been used to treat fungal infections previously. It has fungistatic activity against C. albicans. Traditional Chinese medicines can be used as complementary medicines to conventional drugs to treat a variety of ailments and diseases. Berberine is a quaternary alkaloid isolated from the traditional Chinese herb, Coptidis Rhizoma, while berberrubine is isolated from the medicinal plant Berberis vulgaris, but is also readily derived from berberine by pyrolysis...
April 2016: Biomedical Reports
https://www.readbyqxmd.com/read/27029119/-study-of-composition-of-plant-extracts-possessing-antimicrobial-effect-against-vibrio-cholerae-el-tor-using-high-performance-liquid-chromatography
#13
O V Markina, E V Maksimenko, N V Markin, N A Selyanskaya, A I Shelokhovich, A B Mazrukho, N I Borisenko
AIM: Study the composition of plant extracts using high-performance liquid chromatography. (HPLC) and evaluation of their antimicrobial effect against Vibrio cholerae El Tor. MATERIALS AND METHODS: Qualitative and quantitative composition of plant extracts was studied using HPLC. Determination of sensitivity of microorganisms to plant extracts was carried out by diffusion into agar method and serial dilutions method. RESULTS: Antibacterial effect of water, water-alcohol and acetone extracts of roots of Limonium gmelinii L...
January 2016: Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii
https://www.readbyqxmd.com/read/27021328/berberine-antifungal-activity-in-fluconazole-resistant-pathogenic-yeasts-action-mechanism-evaluated-by-flow-cytometry-and-biofilm-growth-inhibition-in-candida-spp
#14
Anderson Ramos da Silva, João Batista de Andrade Neto, Cecília Rocha da Silva, Rosana de Sousa Campos, Rose Anny Costa Silva, Daniel Domingues Freitas, Francisca Bruna Stefany Aires do Nascimento, Larissa Nara Dantas de Andrade, Letícia Serpa Sampaio, Thalles Barbosa Grangeiro, Hemerson Iury Ferreira Magalhães, Bruno Coêlho Cavalcanti, Manoel Odorico de Moraes, Hélio Vitoriano Nobre Júnior
The incidence of fungal infections and, in particular, the incidence of fungal antibiotic resistance, which is associated with biofilm formation, have significantly increased, contributing to morbidity and mortality. Thus, new therapeutic strategies need to be developed. In this context, natural products have emerged as a major source of possible antifungal agents. Berberine is a protoberberine-type isoquinoline alkaloid isolated from the roots, rhizomes, and stem bark of natural herbs, such as Berberis aquifolium, Berberis vulgaris, Berberis aristata, and Hydrastis canadensis, and of Phellodendron amurense Berberine has been proven to have broad antibacterial and antifungal activity...
June 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/26772915/microencapsulation-optimization-of-natural-anthocyanins-with-maltodextrin-gum-arabic-and-gelatin
#15
Sahar Akhavan Mahdavi, Seid Mahdi Jafari, Elham Assadpoor, Danial Dehnad
The barberry (Berberis vulgaris) extract which is a rich source of anthocyanins was used for spray drying encapsulation with three different wall materials, i.e., combination of maltodextrin and gum Arabic (MD+GA), maltodextrin and gelatin (MD+GE), and maltodextrin (MD). Response Surface Methodology (RSM) was applied for optimization of microencapsulation efficiency and physical properties of encapsulated powders considering wall material type as well as different ratios of core to wall materials as independent variables...
April 2016: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/26693406/a-quick-overview-on-some-aspects-of-endocrinological-and-therapeutic-effects-of-berberis-vulgaris-l
#16
REVIEW
Ali Zarei, Saeed Changizi-Ashtiyani, Soheila Taheri, Majid Ramezani
Many herbaceous plants contain compounds that have biological effects in addition to their medicinal properties. They have compounds with numerous properties, including hypo lipidemic, hypoglycemic, antioxidant, and hepato protective ones, which have been analyzed at different levels. One of these plants, with the scientific name of Berberis vulgaris, is barberry. The most important compounds identified in this plant are berberine, oxycontin, palmatine, bervulcine, berbamine, columbamine, jatrorrhizine, coptisine, and berbamine...
November 2015: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/26669104/-chenabinol-revised-nmr-data-and-two-new-alkaloids-from-berberis-vulgaris-and-their-biological-activity
#17
Zdenĕk Novák, Anna Hošt'álková, Lubomír Opletal, Lucie Nováková, Martina Hrabinová, Jiří Kuneš, Lucie Cahlíková
A known alkaloid (+)-chenabinol (1) and two new secobisbenzylisoquinoline alkaloids were isolated by standard chromatographic methods from the root bark of Berberis vulgaris L. The structures of the new alkaloids, named berkristine (2) and verfilline (3), were established by spectroscopic (including 2D NMR), and HRMS (ESI) methods. The alkaloids were tested for their inhibition activity of human cholinesterases and prolyl oligopeptidase. Compound 1 inhibited human butyrylcholinesterase with an IC50 value of 44...
October 2015: Natural Product Communications
https://www.readbyqxmd.com/read/26647620/a-prospective-pharmacological-review-of-medicinal-herbs-cucumis-melo-and-berberis-vulgaris-commonly-used-in-the-treatment-of-renal-diseases-in-pakistan
#18
Naveed Ullah, Salimullah Khan, Abad Khan, Waqar Ahmad, Yasar Shah, Lateef Ahmad, Ihsan Ullah
The kidneys are important organs which have many functions in the body, including the production of hormones, absorbtion of minerals and the filtration of blood, producing urine. Their failure can be fatal, therefore, to focus the study of such herbs which may be useful in treating renal disease is the need of hour. In Pakistan, Cucumis melo and Berberis vulgaris has been commonly used for renal problems. In both of these plants were found flavonoids, alkaloids and terpenes, which may stand for their renal protective properties...
July 2015: Acta Poloniae Pharmaceutica
https://www.readbyqxmd.com/read/26639503/hypoglycemic-effects-of-three-iranian-edible-plants-jujube-barberry-and-saffron-correlation-with-serum-adiponectin-level
#19
COMPARATIVE STUDY
Mina Hemmati, Somaye Asghari, Elham Zohoori, Mehdi Karamian
One of the most common disorders of the endocrine system is diabetes mellitus. This disease is associated with dyslipidemia. Adiponectin is a protein hormone that secreted by adipocytes and has an important role in regulating of glucose and fatty acid metabolic pathways. This study was designed to investigate the changes in serum level of adiponectin in diabetic rats treated with hydroalcoholic extracts of three medicinal plants; jujube (Ziziphus jujuba), barberry (Berberis vulgaris) and saffron (Crocus sativus) in comparison with quercetin...
November 2015: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/26639472/histopathological-evaluation-of-gastro-protective-effect-of-berberis-vulgaris-zereshk-seeds-against-aspirin-induced-ulcer-in-albino-mice
#20
COMPARATIVE STUDY
Wafa Majeed, Bilal Aslam, Ijaz Javed, Tanweer Khaliq, Faqir Muhammad, Asghar Ali, Ahmed Raza
The present study was carried out to investigate the antiulcer activity of Berberis vulgaris (Zereshk) seeds in albino mice. After acclimatization, animals were divided into six equal groups. Aspirin 150 mg/kg was used to induce gastric ulcer in all groups except normal control. Omeprazole 20mg/kg was used as synthetic anti ulcer drug in study. Three dose levels of B. vulgaris seed powder 300 mg/kg, 600 mg/kg and 900 mg/kg were used respectively orally. Histopathological analysis was carried out to evaluate the gastroprotective activity of B...
November 2015: Pakistan Journal of Pharmaceutical Sciences
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