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https://www.readbyqxmd.com/read/19877554/poor-outcome-in-patients-with-diffuse-large-b-cell-lymphoma-is-associated-with-high-percentage-of-bcl-2-and-ki-67-positive-tumor-cells
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Maja Perunicić Jovanović, Ljubomir Jaković, Andrija Bogdanović, Olivera Marković, Vesna Cemerikić Martinović, Biljana Mihaljević
BACKGROUND/AIM: Newly diagnosed patients with diffuse large B-cell lymphoma (DLBCL) tretaed with immunochemotherapy have durable remission and improved overall survival. It is important to identify high risk patients who may benefit from even more effective therapies. METHODS: In a group of 50 newly diagnosed patients with DLBCL, treated with CHOP/R-CHOP (cyclophosphemide doxorubicine, vincristine, prednisone with or without rituximab) regimen, we analyzed the prognostic value of the expression of Ki67 and bcl-2 at diagnosis as well as other standard clinical parameters: International Prognostic Index (IPI), bulky disease, extranodal distribution and lactat dehydrogenase (LDH)...
September 2009: Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review
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