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https://www.readbyqxmd.com/read/28108856/diagnosis-and-management-for-trigeminal-neuralgia-caused-solely-by-venous-compression
#1
Takuro Inoue, Hisao Hirai, Ayako Shima, Fumio Suzuki, Takanori Fukushima, Masayuki Matsuda
BACKGROUND: Trigeminal neuralgia (TN) caused solely by venous compression is uncommon. An appropriate vein management protocol for microvascular decompression (MVD) has not been established. We evaluated the management of veins for TN solely due to venous involvement. METHOD: We analyzed 31 patients with TN in whom only veins were manipulated during MVD. The culprit veins smaller in diameter than the vein of the cerebellopontine fissure (VCPF) were coagulated and divided in 20 patients (divided group), while transposition was performed for larger veins in the remaining 11 patients (non-divided group)...
January 20, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28108837/can-mechanical-imaging-increase-the-specificity-of-mammography-screening
#2
Magnus Dustler, Daniel Förnvik, Pontus Timberg, Ingvar Andersson, Hannie Petersson, Håkan Brorson, Anders Tingberg, Sophia Zackrisson
OBJECTIVES: This study aimed to investigate the effects of adding adjunct mechanical imaging to mammography breast screening. We hypothesized that mechanical imaging could detect increased local pressure caused by both malignant and benign breast lesions and that a pressure threshold for malignancy could be established. The impact of this on breast screening was investigated with regard to reductions in recall and biopsy rates. METHODS: 155 women recalled from breast screening were included in the study, which was approved by the regional ethical review board (dnr 2013/620)...
January 20, 2017: European Radiology
https://www.readbyqxmd.com/read/28108557/low-level-mhc-class-ii-expression-leads-to-suboptimal-th-cell-response-increased-autoaggression-and-heightened-cytokine-inducibility
#3
Yi-Ting Chen, Yu-Chia Su, Mei-Ling Chang, Pi-Fang Tsai, John T Kung
The development and activation of MHC class II (MHC-II)-restricted CD4(+) T cells are distinct immunological processes that are strictly MHC-II-dependent. To address their relative dependence on MHC-II, we established a novel ENU-induced mutant mouse on the C57BL/6 background, named I-A(12%), with ∼8-fold reduced I-A expression on the surface of B cells, dendritic cells, cortical thymic epithelial cells, and medullary thymic epithelial cells. I-A(100%) and I-A(12%) mice are highly similar with respect to the numbers of double-positive thymocytes, CD4(+)CD8(-) T cells, regulatory T cells, CD4(+) T cell marker expression, lifespan, and Th/regulatory T cell function...
January 20, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28107392/upon-accounting-for-the-impact-of-isoenzyme-loss-gene-deletion-costs-anticorrelate-with-their-evolutionary-rates
#4
Christopher Jacobs, Luke Lambourne, Yu Xia, Daniel Segrè
System-level metabolic network models enable the computation of growth and metabolic phenotypes from an organism's genome. In particular, flux balance approaches have been used to estimate the contribution of individual metabolic genes to organismal fitness, offering the opportunity to test whether such contributions carry information about the evolutionary pressure on the corresponding genes. Previous failure to identify the expected negative correlation between such computed gene-loss cost and sequence-derived evolutionary rates in Saccharomyces cerevisiae has been ascribed to a real biological gap between a gene's fitness contribution to an organism "here and now" and the same gene's historical importance as evidenced by its accumulated mutations over millions of years of evolution...
2017: PloS One
https://www.readbyqxmd.com/read/28107219/do-neurocognitive-scat3-baseline-test-scores-differ-between-footballers-soccer-living-with-and-without-disability-a-cross-sectional-study
#5
Richard Weiler, Willem van Mechelen, Colin Fuller, Osman Hassan Ahmed, Evert Verhagen
OBJECTIVE: To determine if baseline Sport Concussion Assessment Tool, third Edition (SCAT3) scores differ between athletes with and without disability. DESIGN: Cross-sectional comparison of preseason baseline SCAT3 scores for a range of England international footballers. SETTING: Team doctors and physiotherapists supporting England football teams recorded players' SCAT 3 baseline tests from August 1, 2013 to July 31, 2014. PARTICIPANTS: A convenience sample of 249 England footballers, of whom 185 were players without disability (male: 119; female: 66) and 64 were players with disability (male learning disability: 17; male cerebral palsy: 28; male blind: 10; female deaf: 9)...
January 17, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28107174/biological-bases-of-human-musicality
#6
Carla Perrone-Capano, Floriana Volpicelli, Umberto di Porzio
Music is a universal language, present in all human societies. It pervades the lives of most human beings and can recall memories and feelings of the past, can exert positive effects on our mood, can be strongly evocative and ignite intense emotions, and can establish or strengthen social bonds. In this review, we summarize the research and recent progress on the origins and neural substrates of human musicality as well as the changes in brain plasticity elicited by listening or performing music. Indeed, music improves performance in a number of cognitive tasks and may have beneficial effects on diseased brains...
January 20, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/28106767/development-and-evaluation-of-e-ca-an-electronic-mobile-based-food-record
#7
Sophie Bucher Della Torre, Isabelle Carrard, Eddy Farina, Brigitta Danuser, Maaike Kruseman
Measures that capture diet as validly and reliably as possible are cornerstones of nutritional research, and mobile-based devices offer new opportunities to improve and simplify data collection. The balance between precision and acceptability of these data collection tools remains debated, and rigorous validations are warranted. Our objective was to develop and evaluate an electronic mobile-based food record for a research setting. We developed e-CA, which includes almost 900 foods and beverages classified in 14 categories and 60 subcategories...
January 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28106758/validation-of-a-smartphone-image-based-dietary-assessment-method-for-pregnant-women
#8
Amy M Ashman, Clare E Collins, Leanne J Brown, Kym M Rae, Megan E Rollo
Image-based dietary records could lower participant burden associated with traditional prospective methods of dietary assessment. They have been used in children, adolescents and adults, but have not been evaluated in pregnant women. The current study evaluated relative validity of the DietBytes image-based dietary assessment method for assessing energy and nutrient intakes. Pregnant women collected image-based dietary records (via a smartphone application) of all food, drinks and supplements consumed over three non-consecutive days...
January 18, 2017: Nutrients
https://www.readbyqxmd.com/read/28106676/a-remarkable-journey-why-the-magnet-recognition-program%C3%A2-continues-to-resonate-today
#9
Muriel Poulin
It has been more than 30 years since an enterprising team of American Academy of Nursing researchers unearthed groundbreaking findings that led to the creation of the American Nurses Credentialing Center's Magnet Recognition Program®. Dr Muriel Poulin, EdD, RN, FAAN, a coauthor of the original Magnet® hospital study, recalls how she and her colleagues opted to take their research in a different direction and address pressing questions that spoke directly to the needs and desires of staff nurses. She shares her thoughts on why the Magnet Recognition Program continues to resonate today...
February 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28106613/relationship-of-sleep-duration-and-regularity-with-dietary-intake-among-preschool-aged-children-with-obesity-from-low-income-families
#10
Megan E Petrov, Kiley B Vander Wyst, Corrie M Whisner, Mihyun Jeong, Michaela Denniston, Michael W Moramarco, Martina R Gallagher, Elizabeth Reifsnider
OBJECTIVE: Diet is a modifiable factor associated with pediatric obesity outcomes, but few studies have evaluated the relationships of sleep duration and regularity on dietary intake of young preschool-aged children. The goal of this study was to evaluate whether short sleep duration and irregular sleep timing were associated with greater calorie, carbohydrate and fat consumption among young children with obesity from low-income families. METHODS: Fifty-one ethnically diverse children aged 2 to 4 years were recruited from the Special Supplemental Nutrition Program for Women, Infants, and Children clinics in a southeast Texas county...
January 17, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28106554/recovery-from-proactive-semantic-interference-in-mild-cognitive-impairment-and-normal-aging-relationship-to-atrophy-in-brain-regions-vulnerable-to-alzheimer-s-disease
#11
David A Loewenstein, Rosie E Curiel, Clinton Wright, Xiaoyan Sun, Noam Alperin, Elzabeth Crocco, Sara J Czaja, Arlene Raffo, Ailyn Penate, Jose Melo, Kimberly Capp, Monica Gamez, Ranjan Duara
BACKGROUND: There is growing evidence that proactive semantic interference (PSI) and failure to recover from PSI may represent early features of Alzheimer's disease (AD). OBJECTIVE: This study investigated the association between PSI, recovery from PSI, and reduced MRI volumes in AD signature regions among cognitively impaired and unimpaired older adults. METHODS: Performance on the LASSI-L (a novel test of PSI and recovery from PSI) and regional brain volumetric measures were compared between 38 cognitively normal (CN) elders and 29 older participants with amnestic mild cognitive impairment (MCI)...
January 18, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28106548/does-the-female-advantage-in-verbal-memory-contribute-to-underestimating-alzheimer-s-disease-pathology-in-women-versus-men
#12
Erin E Sundermann, Anat Biegon, Leah H Rubin, Richard B Lipton, Susan Landau, Pauline M Maki
There is a growing recognition of sex differences in Alzheimer's disease (AD). Females show an advantage over males on tests of verbal memory, which are used to diagnose AD and its precursor, amnestic mild cognitive impairment (aMCI). Women retain this advantage in aMCI despite reduced hippocampal volume and temporal lobe glucose metabolism. Here we examined whether this female advantage endures despite evidence of AD-specific pathology, cortical amyloid-β (Aβ) deposition measured with [18F]AV45 (florbetapir) positron emission tomography...
January 18, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28105947/superpixel-based-segmentation-of-muscle-fibers-in-multi-channel-microscopy
#13
Binh P Nguyen, Hans Heemskerk, Peter T C So, Lisa Tucker-Kellogg
BACKGROUND: Confetti fluorescence and other multi-color genetic labelling strategies are useful for observing stem cell regeneration and for other problems of cell lineage tracing. One difficulty of such strategies is segmenting the cell boundaries, which is a very different problem from segmenting color images from the real world. This paper addresses the difficulties and presents a superpixel-based framework for segmentation of regenerated muscle fibers in mice. RESULTS: We propose to integrate an edge detector into a superpixel algorithm and customize the method for multi-channel images...
December 5, 2016: BMC Systems Biology
https://www.readbyqxmd.com/read/28105790/a-qualitative-study-of-patients-knowledge-and-views-of-about-oral-health-and-acceptability-of-related-intervention-in-an-australian-inpatient-alcohol-and-drug-treatment-facility
#14
Alison Li Sun Cheah, Ram Pandey, Mark Daglish, Pauline J Ford, Sue Patterson
Social factors, health behaviours and the direct effects of substances contribute to the poor oral health and restricted access to dental services experienced by people who are dependent on drugs and/or alcohol. Admission for inpatient withdrawal management provides an opportunity for intervention to promote oral health but to be effective it must be acceptable to patients. To support intervention design, we examined patients' views about oral health, practices and treatment access, and appropriateness of health-promoting intervention in this context...
January 20, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28105786/development-of-a-reference-database-for-assessing-dietary-nitrate-in-vegetables
#15
Lauren C Blekkenhorst, Richard L Prince, Natalie C Ward, Kevin D Croft, Joshua R Lewis, Amanda Devine, Sujata Shinde, Richard J Woodman, Jonathan M Hodgson, Catherine P Bondonno
SCOPE: Nitrate from vegetables improves vascular health with short term intake. Whether this translates into improved long term health outcomes has yet to be investigated. To enable reliable analysis of nitrate intake from food records there is a strong need for a comprehensive nitrate content of vegetables database. METHODS AND RESULTS: A systematic literature search (1980-2016) was performed using Medline, Agricola and CAB abstracts databases. The nitrate content of vegetables database contains 4237 records from 255 publications with data on 178 vegetables and 22 herbs and spices...
January 19, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28105242/skin-toxicity-in-a-patient-with-ovarian-cancer-treated-with-pegylated-liposomal-doxorubicin-a-case-report-and-review-of-the-literature
#16
Joanna Kubicka-Wołkowska, Magdalena Kędzierska, Maja Lisik-Habib, Piotr Potemski
Pegylated liposomal doxorubicin (PLD) is a form of doxorubicin enclosed in pegylated liposomes. In contrast to conventional doxorubicin, PLD is characterized by a lower incidence of cardiotoxicity and myelosuppression. However, it induces specific mucocutaneous side effects, particularly palmar-plantar erythrodysesthesia (PPE). Other dermal manifestations, such as intertrigo-like dermatitis, diffuse follicular rash, melanotic macules, maculopapular rash or recall phenomenon are less common. Mechanisms that lead to skin toxicity remain unclear, however, certain reports indicate that drug excretion in sweat, host-vs...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28104542/hippocampal-morphology-and-cognitive-functions-in-community-dwelling-older-people-the-lothian-birth-cohort-1936
#17
Maria Del Carmen Valdés Hernández, Simon R Cox, Jaeil Kim, Natalie A Royle, Susana Muñoz Maniega, Alan J Gow, Devasuda Anblagan, Mark E Bastin, Jinah Park, John M Starr, Joanna M Wardlaw, Ian J Deary
Structural measures of the hippocampus have been linked to a variety of memory processes and also to broader cognitive abilities. Gross volumetry has been widely used, yet the hippocampus has a complex formation, comprising distinct subfields which may be differentially sensitive to the deleterious effects of age, and to different aspects of cognitive performance. However, a comprehensive analysis of multidomain cognitive associations with hippocampal deformations among a large group of cognitively normal older adults is currently lacking...
December 21, 2016: Neurobiology of Aging
https://www.readbyqxmd.com/read/28104042/electronic-health-records-and-online-medical-records-an-asset-or-a-liability-under-current-conditions
#18
Judith Allen-Graham, Lauren Mitchell, Natalie Heriot, Roksana Armani, David Langton, Michele Levinson, Alan Young, Julian A Smith, Tom Kotsimbos, John W Wilson
Objective The aim of the present study was to audit the current use of medical records to determine completeness and concordance with other sources of medical information.Methods Medical records for 40 patients from each of five Melbourne major metropolitan hospitals were randomly selected (n=200). A quantitative audit was performed for detailed patient information and medical record keeping, as well as data collection, storage and utilisation. Using each hospital's current online clinical database, scanned files and paperwork available for each patient audited, the reviewers sourced as much relevant information as possible within a 30-min time allocation from both the record and the discharge summary...
January 20, 2017: Australian Health Review: a Publication of the Australian Hospital Association
https://www.readbyqxmd.com/read/28103149/gender-and-appearance-accuracy-women-s-advantage-over-men-is-restricted-to-dress-items
#19
Terrence Glenn Horgan, Marianne Patricia McGrath, Carl Bastien, Patrick Wegman
Which aspects of people's appearance do women remember better than men do? Women were predicted to remember the dress-related items but not the physical characteristics of targets more accurately than men, given that the former might be a more female-relevant domain of interest among perceivers. Participants watched a videotaped target and then completed a surprise test of their memory for her/his appearance. Men were as accurate as women at remembering the target's physical features, but less accurate than woman at recalling what the target was wearing...
January 19, 2017: Journal of Social Psychology
https://www.readbyqxmd.com/read/28102492/persistent-cognitive-deficits-after-whiplash-injury-a-comparative-study-with-mild-traumatic-brain-injury-patients-and-healthy-volunteers
#20
Kurt Beeckmans, Cleo Crunelle, Silke Van Ingelgom, Karla Michiels, Eva Dierckx, Patrick Vancoillie, Henri Hauman, Bernard Sabbe
In this study, we evaluated persistent cognitive deficits in whiplash injury (WI) patients and compared these to cognitive functioning in mild traumatic brain injury (MTBI) patients and healthy controls (HC). Sixty-one patients suffering from a WI were compared with 57 patients suffering from a MTBI and with 30 HC. They were examined with an extensive neuropsychological test battery assessing attention, memory, and visuospatial and executive functions. In both patient groups, participants showed persistent cognitive symptoms (more than 6 months post-injury)...
January 19, 2017: Acta Neurologica Belgica
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