Saleh A Almatroodi, Ahmad Almatroudi, Hajed Obaid A Alharbi, Amjad Ali Khan, Arshad Husain Rahmani
Luteolin, a flavonoid, is mainly found in various vegetables and fruits, including carrots, cabbages, onions, parsley, apples, broccoli, and peppers. Extensive research in vivo and in vitro has been performed to explore its role in disease prevention and treatment. Moreover, this compound possesses the ability to combat cancer by modulating cell-signaling pathways across various types of cancer. The studies have confirmed that luteolin can inhibit cancer-cell survival and proliferation, angiogenesis, invasion, metastasis, mTOR/PI3K/Akt, STAT3, Wnt/β-catenin, and cell-cycle arrest, and induce apoptosis...
February 29, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry