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https://www.readbyqxmd.com/read/29776453/dye-residue-analysis-in-raw-and-processed-aquaculture-products-matrix-extension-of-aoac-international-official-method-%C3%A2-2012-25
#1
Wendy C Andersen, Christine R Casey, Tara J Nickel, Susan L Young, Sherri B Turnipseed
Background : Triphenylmethane dyes and metabolites are known or suspected mutagens and areprohibited in animals intended for human consumption. Despite toxicity, triphenylmethane dyes are used illegally as inexpensive treatments for fungal and parasite infections in aquatic animals. Objective: AOAC INTERNTIONAL Official Method ℠ 2012.25 for the LC-MS/MS determination of malachite green, crystal violet, brilliant green, and metabolites leucomalachite green and leucocrystal violet in seafood products was previously validated for finfish (trout, salmon, catfish, and tilapia) and shrimp, but had not been fully validated for other types of aquacultured products such as eel, molluscan shellfish, or frog or for processed seafoods...
May 18, 2018: Journal of AOAC International
https://www.readbyqxmd.com/read/29769381/tosr-mediated-regulation-of-adhesins-and-biofilm-formation-in-uropathogenic-escherichia-coli
#2
Courtney L Luterbach, Valerie S Forsyth, Michael D Engstrom, Harry L T Mobley
Uropathogenic Escherichia coli strains utilize a variety of adherence factors that assist in colonization of the host urinary tract. TosA (<u>t</u>ype <u>o</u>ne <u>s</u>ecretion <u>A</u>) is a nonfimbrial adhesin that is predominately expressed during murine urinary tract infection (UTI), binds to kidney epithelial cells, and promotes survival during invasive infections. The tosRCBDAEF operon encodes the secretory machinery necessary for TosA localization to the E...
June 27, 2018: MSphere
https://www.readbyqxmd.com/read/29764457/video-mediastinoscopy-assisted-fish-bone-extraction-and-superior-medistinal-abscess-debridement
#3
Jun Wang, Wei Bing Wu, Liang Chen, Quan Zhu
BACKGROUND: Mediastinum abscess caused by sharp esophageal foreign body perforation usually needs surgical treatment, and the surgical procedures vary according to size of perforation and scope of abscess, etc. For special case with small esophageal mucosal crevasse and focal abscess confined to mediastinum, minimally invasive surgery with guidance of video-mediastinoscopy would be an alternative method, however, application of video-mediastinoscopy in this life-threatening situation was rarely reported...
May 15, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29764104/the-response-to-and-impact-of-the-ebola-epidemic-towards-an-agenda-for-interdisciplinary-research
#4
Michael Calnan, Erica W Gadsby, Mandy Kader Kondé, Abdourahime Diallo, Jeremy S Rossman
BACKGROUND: The 2013-2016 Ebola virus disease (EVD) epidemic in West Africa was the largest in history and resulted in a huge public health burden and significant social and economic impact in those countries most affected. Its size, duration and geographical spread presents important opportunities for research than might help national and global health and social care systems to better prepare for and respond to future outbreaks. This paper examines research needs and research priorities from the perspective of those who directly experienced the EVD epidemic in Guinea...
September 3, 2017: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/29740383/nervous-system-injury-and-neuroimaging-of-zika-virus-infection
#5
REVIEW
Shanshan Wu, Yu Zeng, Alexander Lerner, Bo Gao, Meng Law
In 2016, World Health Organization announced Zika virus infection and its neurological sequalae are a public health emergency of global scope. Preliminary studies have confirmed a relationship between Zika virus infection and certain neurological disorders, including microcephaly and Guillain-Barre syndrome (GBS). The neuroimaging features of microcephaly secondary to Zika virus infection include calcifications at the junction of gray-white matter and subcortical white matter with associated cortical abnormalities, diminution of white matter, large ventricles with or without hydrocephalus, cortical malformations, hypoplasia of cerebellum and brainstem, and enlargement of cerebellomedullary cistern...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29733243/managing-an-epidemic-zika-interventions-and-community-responses-in-belize
#6
Deven Gray, Joanna Mishtal
Implementing effective health interventions in recent epidemics has been difficult due to the potentially global nature of their spread and sociocultural dynamics, raising questions concerning how to develop culturally-appropriate preventive measures, and how these health threats are understood locally. In Belize, health policy makers have only been marginally effective in managing infections and mosquito vectors, and Zika has been declared endemic in certain regions, particularly on the island of Caye Caulker...
May 7, 2018: Global Public Health
https://www.readbyqxmd.com/read/29732990/ozenoxacin-a-novel-drug-discovery-for-the-treatment-of-impetigo
#7
Jagdish K Sahu, Arun K Mishra
OBJECTIVE: Ozenoxacin is one of the potent quinolone antibiotics, recently approved by the United States Food and Drug Administration (USFDA) with reported pharmacology to treat the impetigo. The demand for better acting topical formulation is increasing day by day. The present review is an attempt to summarize the facts behind the chemistry and biological applications of Ozenoxacin. Mechanism of action: This novel drug being a quinolone antibiotic compound, acts by inhibiting DNA gyrase A and topoisomerase IV and affects supercoiling, supercoil relaxation, chromosomal condensation, chromosomal decatenation and many others...
May 2, 2018: Current Drug Discovery Technologies
https://www.readbyqxmd.com/read/29729831/infection-control-iv-moving-forward-infection-preventionists-scope-of-practice
#8
Harold W Horowitz
No abstract text is available yet for this article.
May 2, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29718884/epidural-versus-intravenous-steroids-application-following-percutaneous-endoscopic-lumbar-discectomy
#9
Annan Hu, Xin Gu, Xiaofei Guan, Guoxin Fan, Shisheng He
Retrospectively study.The purpose of this study was to compare the effects of intraoperative epidural steroids and single dose intravenous steroids following a percutaneous endoscopic lumbar discectomy (PELD).Inflammatory irritation of dorsal root ganglia or sensory nerve roots may cause postoperative pain. Epidural steroids have been applied after a lumbar discectomy for more than 20 years. Epidural steroid application after a PELD is easier to perform and safer because the operations are under observation of the scope...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29713570/hepatitis-c-infection-patterns-at-a-tertiary-care-center-in-new-york-a-cross-sectional-study
#10
Ahmed Mahgoub, Talal El Imad, Hassan Al Moussawi, Danial Daneshvar, Fady G Haddad, Joseph Saabiye, George Abdelsayed, Sherif Andrawes, Liliane Deeb
Introduction In the United States, 2.7 to 3.9 million patients are infected with the hepatitis C virus (HCV) with 3,500 new cases reported yearly. According to the Centers for Disease Control and Prevention, HCV was the underlying or contributing cause of death of 19,659 patients in 2014. These facts underscore the need for a better understanding of the scope of this disease. Our epidemiologic study aimed at analyzing the pattern of occurrence of HCV infection at Staten Island University Hospital (SIUH) by evaluating the characteristics of newly infected patients with hepatitis C in 2014...
February 26, 2018: Curēus
https://www.readbyqxmd.com/read/29713447/over-the-scope-clip-otsc%C3%A2-closure-of-a-recto-acetabular-fistula
#11
Tobias S Schiergens, Cord-Christian Becker, Patrick Weber, Alena Sint, Markus Albertsmeier, Bernhard W Renz, Maria Burian, Axel Kleespies, Angela Reichelt, Markus O Guba, Markus Rentsch, Jens Werner, Christian P Schneider
A 25-year-old male Syrian refugee presented in our hospital with recurrent hip infections after having undergone hip arthroplasty abroad following destruction of his right hip joint by shell splinters in the Syrian civil war. The patient underwent hip arthroplasty revision with implantation of a cement spacer. CT-scan with rectal contrast media filling revealed a recto-acetabular fistula. Consecutively, the patient underwent ileostomy formation. The fistula was then successfully closed by endoscopic over-the-scope clipping (OTSC® )...
April 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29708490/audiology-assistants-results-of-a-multicenter-survey
#12
Roanne Karzon, Lisa Hunter, Wendy Steuerwald
BACKGROUND: Although audiologists have been using support personnel for over 45 yr, controversy and variability continue with respect to the entry-level education, training methods, and scope of practice. PURPOSE: As part of a larger clinical practices survey, this report focuses on use of audiology assistants (AAs) for pediatric settings and "life-span" facilities that had a significant population of pediatric patients. RESEARCH DESIGN: A questionnaire was sent to 116 facilities in geographically diverse locations...
May 2018: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/29707388/risk-factors-and-co-morbidities-associated-with-changes-in-renal-function-among-antiretroviral-treatment-na%C3%A3-ve-adults-in-south-africa-a-chart-review
#13
Shirelle Assaram, Tivani P Mashamba-Thompson, Nombulelo P Magula
Introduction: Our systematic scoping review has demonstrated a research gap in antiretroviral treatment (ART) nephrotoxicity as well as in the long-term outcomes of renal function for patients on ART in South Africa. Bearing in mind the high prevalence of human immunodeficiency virus (HIV) in South Africa, this is of great concern. Objectives: To determine the risk factors and co-morbidities associated with changes in renal function in HIV-infected adults in South Africa...
2018: Southern African Journal of HIV Medicine
https://www.readbyqxmd.com/read/29701090/a-consensus-exercise-identifying-priorities-for-research-into-clinical-effectiveness-among-children-s-orthopaedic-surgeons-in-the-united-kingdom
#14
D C Perry, J G Wright, S Cooke, A Roposch, M S Gaston, N Nicolaou, T Theologis
Aims High-quality clinical research in children's orthopaedic surgery has lagged behind other surgical subspecialties. This study used a consensus-based approach to identify research priorities for clinical trials in children's orthopaedics. Methods A modified Delphi technique was used, which involved an initial scoping survey, a two-round Delphi process and an expert panel formed of members of the British Society of Children's Orthopaedic Surgery. The survey was conducted amongst orthopaedic surgeons treating children in the United Kingdom and Ireland...
May 1, 2018: Bone & Joint Journal
https://www.readbyqxmd.com/read/29698934/a-review-of-clinical-radioprotection-and-chemoprotection-for-oral-mucositis
#15
REVIEW
Bryan Oronsky, Sharad Goyal, Michelle M Kim, Pedro Cabrales, Michelle Lybeck, Scott Caroen, Neil Oronsky, Erica Burbano, Corey Carter, Arnold Oronsky
The first tenet of medicine, "primum non nocere" or "first, do no harm", is not always compatible with oncological interventions e.g., chemotherapy, targeted therapy and radiation, since they commonly result in significant toxicities. One of the more frequent and serious treatment-induced toxicities is mucositis and particularly oral mucositis (OM) described as inflammation, atrophy and breakdown of the mucosa or lining of the oral cavity. The sequelae of oral mucositis (OM), which include pain, odynodysphagia, dysgeusia, decreased oral intake and systemic infection, frequently require treatment delays, interruptions and discontinuations that not only negatively impact quality of life but also tumor control and survivorship...
April 23, 2018: Translational Oncology
https://www.readbyqxmd.com/read/29694574/sexual-violence-against-children-authors-victims-and-consequences
#16
Vanessa Borges Platt, Isabela de Carlos Back, Daniela Barbieri Hauschild, Jucélia Maria Guedert
The scope of this study was to identify the characteristics of sexual abuse against children including the profiles of the victims and the perpetrators, and associated factors notified in a health service of reference with the database of the Brazilian Case Registry Database, in a city in the south of Brazil. Categorical variables are presented in prevalence with 95% confidence intervals. There were 489 notifications from 2008 to 2014 of confirmed or suspected child sexual abuse. The majority was related to female victims, but the repeated abuse was reported mainly with male victims...
April 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29686960/shifting-the-paradigm-of-emergency-care-in-developing-countries
#17
Ayesha Khan, Bradley T Penoff, Elizabeth A Pirrotta, Robert Hosang
Background The global agenda does not address a significant amount of preventable death in low- and middle-income countries (LMICs). While illnesses requiring acute care are increasing at an alarming rate in these countries, there are inadequate numbers of physicians or nurses to deal with the growing burden. Many people feel that emergency systems are too expensive and restricted in scope to have public health implications in resource-limited areas. Little empirical data exists to suggest otherwise. The goal of this study was to delineate the type and frequency of emergency conditions and define a novel method to estimate the burden of emergency diseases in Fort Liberte, Haiti...
February 22, 2018: Curēus
https://www.readbyqxmd.com/read/29670614/human-v%C3%AE-9v%C3%AE-2-t-cells-synergize-cd4-t-follicular-helper-cells-to-produce-influenza-virus-specific-antibody
#18
Qingyun Chen, Kun Wen, Aizhen Lv, Ming Liu, Ke Ni, Zheng Xiang, Yinping Liu, Wenwei Tu
Human Vγ9Vδ2-T cells recognize nonpeptidic antigens and exert effector functions against microorganisms and tumors, but little is known about their roles in humoral immune response against influenza virus infection. Herein, in the coculture of autologous human B cells, dendritic cells and/or naïve CD4 T cells, and Vγ9Vδ2-T cells, we demonstrated that Vγ9Vδ2-T cells could facilitate H9N2 influenza virus-specific IgG and IgM productions in a CD4 T cell-dependent manner. Vγ9Vδ2-T cells promoted the differentiation of CXCR5+ PD1+ CD4+ T follicular helper (Tfh) cells, CD19+ IgD- CD38++ plasma cells (PCs), and drove B cell proliferation as well as immunoglobulin class switching...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29655666/environmental-considerations-in-the-selection-of-isolation-gowns-a-life-cycle-assessment-of-reusable-and-disposable-alternatives
#19
Eric Vozzola, Michael Overcash, Evan Griffing
BACKGROUND: Isolation gowns serve a critical role in infection control by protecting healthcare workers, visitors, and patients from the transfer of microorganisms and body fluids. The decision of whether to use a reusable or disposable garment system is a selection process based on factors including sustainability, barrier effectiveness, cost, and comfort. Environmental sustainability is increasingly being used in the decision-making process. Life cycle assessment is the most comprehensive and widely used tool used to evaluate environmental performance...
April 11, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29652100/how-should-hiv-resources-be-allocated-lessons-learnt-from-applying-optima-hiv-in-23-countries
#20
REVIEW
Robyn M Stuart, Laura Grobicki, Hassan Haghparast-Bidgoli, Jasmina Panovska-Griffiths, Jolene Skordis, Olivia Keiser, Janne Estill, Zofia Baranczuk, Sherrie L Kelly, Iyanoosh Reporter, David J Kedziora, Andrew J Shattock, Janka Petravic, S Azfar Hussain, Kelsey L Grantham, Richard T Gray, Xiao F Yap, Rowan Martin-Hughes, Clemens J Benedikt, Nicole Fraser-Hurt, Emiko Masaki, David J Wilson, Marelize Gorgens, Elizabeth Mziray, Nejma Cheikh, Zara Shubber, Cliff C Kerr, David P Wilson
INTRODUCTION: With limited funds available, meeting global health targets requires countries to both mobilize and prioritize their health spending. Within this context, countries have recognized the importance of allocating funds for HIV as efficiently as possible to maximize impact. Over the past six years, the governments of 23 countries in Africa, Asia, Eastern Europe and Latin America have used the Optima HIV tool to estimate the optimal allocation of HIV resources. METHODS: Each study commenced with a request by the national government for technical assistance in conducting an HIV allocative efficiency study using Optima HIV...
April 2018: Journal of the International AIDS Society
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