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https://www.readbyqxmd.com/read/28042321/pre-vascularization-enhances-therapeutic-effects-of-human-mesenchymal-stem-cell-sheets-in-full-thickness-skin-wound-repair
#1
Lei Chen, Qi Xing, Qiyi Zhai, Mitchell Tahtinen, Fei Zhou, Lili Chen, Yingbin Xu, Shaohai Qi, Feng Zhao
Split thickness skin graft (STSG) implantation is one of the standard therapies for full thickness wound repair when full thickness autologous skin grafts (FTG) or skin flap transplants are inapplicable. Combined transplantation of STSG with dermal substitute could enhance its therapeutic effects but the results remain unsatisfactory due to insufficient blood supply at early stages, which causes graft necrosis and fibrosis. Human mesenchymal stem cell (hMSC) sheets are capable of accelerating the wound healing process...
2017: Theranostics
https://www.readbyqxmd.com/read/28041749/minced-skin-grafting-for-promoting-epithelialization-of-the-donor-site-after-split-thickness-skin-grafting
#2
Toru Miyanaga, Yasuo Haseda, Akihiko Sakagami
It is important to minimize time to healing in the donor site after split-thickness skin grafting (STSG). It has been shown that minced skin grafting improves the appearance of the STSG donor site. The objective of this study was to investigate whether mincing the leftover harvested skin and grafting it back onto the donor site during minced grafting (MG) reduces healing time of the donor site. Normal healing time of the donor site after STSG is 10-20 days; therefore, healing time more than a month is abnormal...
December 29, 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28028957/allogeneic-vs-autologous-skin-grafts-in-the-therapy-of-patients-with-burn-injuries-a-restrospective-open-label-clinical-study-with-pair-matching
#3
Diana Kitala, Marek Kawecki, Agnieszka Klama-Baryła, Wojciech Łabuś, Małgorzata Kraut, Justyna Glik, Ireneusz Ryszkiel, Marek P Kawecki, Mariusz Nowak
BACKGROUND: Early application of autologous skin may lead to the loss of split thickness skin graft due to unclarified wound bed. Allogeneic skin grafts are performed on patients with extensive burn injuries after escharotomy, tangential excisions and deep debridement for the purpose of stabilizing the general condition and reducing the scope of local complications. OBJECTIVES: The aim of this paper is to determine how the use of allografts improves the conditions for the intake of autografts in burns treatment, and how it accelerates wound healing in comparison to the autografts-only option...
September 2016: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28012339/rare-nodular-malignant-melanoma-of-the-heel-in-the-caribbean-a-case-report
#4
Wayne A Warner, Vandana Devika Sookdeo, Srikanth Umakanthan, Kevin Sarran, Lemuel Pran, Maurice Fortuné, Wesley Greaves, Sharda Narinesingh, Dave Harnanan, Ravi Maharaj
INTRODUCTION: Malignant melanoma of the heel is a rare melanoma subtype with incidence rates that reflect the complex relationship between sun exposure at certain geographic locations, individual melanin levels and overall melanoma risk. It is oftentimes characterized by poor prognosis because of delays in presentation resulting in longitudinal tumor invasion, lymph node involvement and metastasis. PRESENTATION OF CASE: A 59-year-old woman was admitted to the Eric Williams Medical Sciences Complex, Trinidad and Tobago with a 5mm pruritic lesion on her left heel...
November 27, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27974988/surgical-management-of-giant-genital-condyloma-acuminata-by-using-double-keystone-flaps
#5
Peri Eriad Yunir, Chaidir A Mochtar, Agus Rizal A H Hamid, Chaula L Sukasah, Rainy Umbas
Condyloma acuminata in the external genitalia (genital warts) is a sexually transmitted disease that is often caused by human papillomavirus (HPV). We report a case of giant genital condyloma acuminata in a 35-year-old male patient with HIV comorbidity treated by wide surgical excision. Excision defect was covered with split thickness skin graft (STSG) and double keystone flaps. There was no complication after surgery. Ten months following surgery, there was no new condyloma lesion and the patient had normal voiding and erectile functions...
2016: Case Reports in Urology
https://www.readbyqxmd.com/read/27974929/crushing-injuries-of-the-foot-and-ankle-with-complex-open-fractures-result-of-a-prospective-study-with-a-3-year-follow-up
#6
Edelstein DA, Florescu I
The objective of this study was to determine the compared results of both the reconstruction surgery and the amputation in severe crushing of the foot, which led to open fractures. The type of study. Prospective. Background. Two major trauma hospitals (Floreasca Clinical Emergency Hospital and "Bagdasar Arseni" Clinical Emergency Hospital) from the university center in Bucharest. Patients. 21 patients, who sustained crushing of the foot with resulting Gustilo type III open fractures, were involved. The exclusion criteria were represented by open fractures that had very gross destructions of the neurovascular bundle, for which the amputation was the only solution, with no modality to reconstruct whatsoever...
July 2016: Journal of Medicine and Life
https://www.readbyqxmd.com/read/27936549/mechanisms-of-sodium-insertion-extraction-on-the-surface-of-defective-graphenes
#7
James C Pramudita, Aditya Rawal, Mohammad Choucair, Daniele Pontiroli, Giacomo Magnani, Mattia Gaboardi, Mauro Riccò, Neeraj Sharma
Two chemically synthesized defective graphene materials with distinctly contrasting extended structures and surface chemistry are used to prepare sodium-ion battery electrodes. The difference in electrode performance between the chemically prepared graphene materials is qualified based on correlations with intrinsic structural and chemical dissimilarities. The overall effects of the materials' physical and chemical discrepancies are quantified by measuring the electrode capacities after repeated charge/discharge cycles...
December 28, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27905181/effectiveness-of-collagen-oxidised-regenerated-cellulose-silver-containing-composite-wound-dressing-for-the-treatment-of-medium-depth-split-thickness-skin-graft-donor-site-wounds-in-multi-morbid-patients-a-prospective-non-comparative-single-centre-study
#8
Alexander Konstantinow, Tatjana V Fischer, Johannes Ring
Split-thickness skin grafting (STSG) is a widely used method in reconstructive surgery, but donor site wounds (DSWs) are often slow healing and painful. This prospective study evaluated the performance of a composite wound dressing containing collagen/oxidised regenerated cellulose in the treatment of medium-depth (0·4 mm) DSWs in 25 multi-morbid patients with chronic leg ulcers requiring STSG. The range of patients' ages was 44-84 years (mean 71·6 years) with DSW sizes ranging between 12 and 162 cm(2) (mean 78 cm(2) )...
December 1, 2016: International Wound Journal
https://www.readbyqxmd.com/read/27810611/management-of-skin-defect-following-resection-of-stage-iv-scalp-melanoma-a-case-report
#9
Yana Puckett, Eileen Bui, Sharmila Dissanaike
INTRODUCTION: Surgical defect left following excision of a large and neglected scalp melanoma of can pose a significant challenge for the surgeon. Scalp reconstruction encompasses options such as skin flaps, grafts, and various mechanical techniques. In scalp excision that involves dissection beyond the galea, skin grafts and flaps may not take well and not enough tissue may be available for a skin flap. PRESENTATION OF CASE: We present the case of a 64 year-old male with a giant scalp melanoma...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27746062/glansectomy-and-split-thickness-skin-graft-for-penile-cancer
#10
Arie S Parnham, Maarten Albersen, Varun Sahdev, Michelle Christodoulidou, Raj Nigam, Peter Malone, Alex Freeman, Asif Muneer
BACKGROUND: Penile cancer is a rare malignancy that is confined to the glans in up to four out of five cases. Although descriptions of glansectomy exist, there are no contemporary video explanations or large published single centre series. OBJECTIVE: To show the efficacy and safety of glansectomy and split-thickness skin graft (STSG) reconstruction. DESIGN, SETTING, AND PARTICIPANTS: Data were collected retrospectively for patients identified from surgical theatre diaries between February 2005 and January 2016...
October 13, 2016: European Urology
https://www.readbyqxmd.com/read/27642803/clinical-application-of-subdermal-areolar-tissue-and-superficial-fascia-graft-as-a-new-material-for-coverage-of-small-exposure-of-bone-cortex-or-orthopaedic-fixation-device
#11
Masahide Gondo, Hajime Matsumura, Katsueki Watanabe
BACKGROUND: The presence of cortical bone, tendon that has been exposed by defects, may result in infection or osteomyelitis. In such cases, perifascial areolar tissue grafting (PATG) may be performed as a minimally invasive surgical procedure. However, perifascial areolar tissue (PAT) is located deep in the subcutaneous layer. It was considered that grafting of the superficial vascular network might enable less invasive surgery. This study reports use of subdermal areolar tissue (SAT) and superficial fascia (SF) to close avascular areas...
September 19, 2016: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/27625025/auricular-split-thickness-skin-graft-for-ear-canal-coverage
#12
Yarah M Haidar, Sartaaj Walia, Ronald Sahyouni, Yaser Ghavami, Harrison W Lin, Hamid R Djalilian
Split-thickness skin graft (STSG) continues to be the preferred means of external auditory canal (EAC) reconstruction. We thus sought to describe our experience using skin from the posterior aspect of the auricle (SPAA) as a donor site in EAC reconstruction. Grafts were, on average, 5 × 10 mm in size and obtained with a No. 10 blade after tumescence injection. The cases of 39 patients who underwent 41 procedures were retrospectively reviewed. Of the 38 patients with both 3- and 6-month follow-ups, no postoperative stenosis or bony exposure occurred...
December 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/27618726/surgical-preparation-of-nasal-defects-to-enhance-the-implant-retained-facial-prostheses-a-case-report
#13
Theresa M Hofstede, Rhonda F Jacob, Patricia Montgomery, Peggy Wesley
BACKGROUND: Skin cancers requiring nasal resection may be surgically reconstructed and/or prosthetically reconstructed. Singular surgical reconstruction may be ideal for smaller defects in which the nasal bone and cartilaginous portions of the nose are maintained, but surgical reconstruction falls short of providing acceptable aesthetic results for more extensive nasal defects. Prosthetic rehabilitation, or a combination of surgical and prosthetic rehabilitation, is more appropriate for larger defects, but prosthesis retention can be challenging when adhesives are required on adjacent mobile and secreting skin...
January 2017: Head & Neck
https://www.readbyqxmd.com/read/27574679/hyperpigmentation-after-surgery-for-a-deep-dermal-burn-of-the-dorsum-of-the-hand-partial-thickness-debridement-followed-by-medium-split-thickness-skin-grafting-vs-full-thickness-debridement-followed-by-thick-split-thickness-skin-grafting
#14
Yoshitaka Kubota, Nobuyuki Mitsukawa, Kumiko Chuma, Shinsuke Akita, Yoshitaro Sasahara, Naoaki Rikihisa, Kaneshige Satoh
BACKGROUND: Early excision and skin grafting are commonly used to treat deep dermal burns (DDBs) of the dorsum of the hand. Partial-thickness debridement (PTD) is one of the most commonly used procedures for the excision of burned tissue of the dorsum of the hand. In contrast, full-thickness debridement (FTD) has also been reported. However, it is unclear whether PTD or FTD is better. METHODS: In this hospital-based retrospective study, we compared the outcomes of PTD followed by a medium split-thickness skin graft (STSG) with FTD followed by a thick STSG to treat a DDB of the dorsum of the hand in Japanese patients...
2016: Burns and trauma
https://www.readbyqxmd.com/read/27441935/split-thickness-skin-graft-to-lower-leg
#15
David A Fuller
PURPOSE: The purpose of this video is to demonstrate the steps of harvesting, meshing, and applying a split thickness skin graft (STSG) to a lower leg to cover a lateral fasciotomy wound. METHODS: A patient with a gunshot wound to his tibia has already undergone intramedullary rodding of the fracture and has had and medial and lateral fasciotomies for compartment syndrome. In the video, the lateral leg wound is covered with an STSG from the ipsilateral, lateral thigh...
August 2016: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/27387706/firefighter-willingness-to-participate-in-a-stem-cell-clinical-trial-for-burns-a-mixed-methods-study
#16
Jenny D Horch, Eloise C J Carr, Patricia Harasym, Lindsay Burnett, Jeff Biernaskie, Vincent Gabriel
: Adult stem cells represent a potentially renewable and autologous source of cells to regenerate skin and improve wound healing. Firefighters are at risk of sustaining a burn and potentially benefiting from a split thickness skin graft (STSG). This mixed methods study examined firefighter willingness to participate in a future stem cell clinical trial, outcome priorities and factors associated with this decision. METHODS: A sequential explanatory mixed methods design was used...
December 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/27335695/demographic-characteristics-and-outcome-of-burn-patients-requiring-skin-grafts-a-tertiary-hospital-experience
#17
Saud Othman Al Shlash, Jamal Omran Al Madani, Jamal Ismail El Deib, Fatemah Suliman Alsubhi, Sara Saud Al Saifi, Ayman Mohammed Adel Helmi, Sultan Khalaf Al-Mutairi, Javed Akhtar Khurram
Split thickness skin graft (STSG) and full thickness skin graft (FTSG) are the integral part of burn wound management. However the impact of these graft types on the outcome still remain a matter of controversy. The purpose of this study was to determine the demographic characteristics and outcome of graft surgery of the patients undergone STSG and FTSG at Plastic Surgery Department of Prince Sultan Military Medical City (PSMMC), Riyadh, Kingdom of Saudi Arabia. This retrospective study included 85 burn patients who received STSG (56 cases) and FTSG (29 cases) at PSMMC during 2010-2015...
2016: International Journal of Burns and Trauma
https://www.readbyqxmd.com/read/27155806/pediatric-penile-reconstruction-using-autologous-split-thickness-skin-graft
#18
E C Diaz, J F Corcoran, E K Johnson
This video provides a case report of penis entrapment secondary to excessive skin removal during circumcision. It highlights the technical aspects of pediatric penile reconstruction using autologous split-thickness skin graft (STSG). Key points include: 1. Infection prevention is paramount and antibiotic prophylaxis is routine. 2. The usual harvest site for the STSG is the lateral thigh because of its source of glabrous skin and convenient proximity to the penis. The lateral thigh is also outside of the diapered area, which helps lessen postoperative pain and infectious risks...
June 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27152580/classification-system-for-individualized-treatment-of-adult-buried-penis-syndrome
#19
Timothy J Tausch, Isamu Tachibana, Jordan A Siegel, Ronald Hoxworth, Jeremy M Scott, Allen F Morey
BACKGROUND: The authors present their experience with reconstructive strategies for men with various manifestations of adult buried penis syndrome, and propose a comprehensive anatomical classification system and treatment algorithm based on pathologic changes in the penile skin and involvement of neighboring abdominal and/or scrotal components. METHODS: The authors reviewed all patients who underwent reconstruction of adult buried penis syndrome at their referral center between 2007 and 2015...
September 2016: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27068845/composite-skin-grafting-with-human-acellular-dermal-matrix-scaffold-for-treatment-of-diabetic-foot-ulcers-a-randomized-controlled-trial
#20
Zhicheng Hu, Jiayuan Zhu, Xiaoling Cao, Chufen Chen, Shuting Li, Dong Guo, Jian Zhang, Peng Liu, Fen Shi, Bing Tang
BACKGROUND: Composite split-thickness skin grafting (STSG) with acellular dermal matrix (ADM) has been used successfully in burn injuries and trauma, but its use in treating diabetic foot ulcers (DFUs) has not been reported to date. This study investigated the efficacy and safety of composite STSG with ADM in the treatment of DFUs. STUDY DESIGN: Fifty-two patients with DFUs were randomized into experimental and control groups. Patients in the experimental group received composite STSG over ADM; the control group received STSG alone...
June 2016: Journal of the American College of Surgeons
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