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https://www.readbyqxmd.com/read/29117823/feasibility-and-advantages-of-full-thickness-skin-graft-from-the-anterolateral-thigh
#1
Seung-Han Shin, Chulkyu Kim, Yong-Suk Lee, Jin-Woo Kang, Yang-Guk Chung
BACKGROUND: Full thickness skin graft (FTSG) gives better outcomes than split thickness skin graft (STSG), but it has the drawback of limited donor sites. Anterolateral thigh (ALT), a popular donor site of STSG, is also a popular donor site of perforator flaps. This area has the advantage of large flap size available with primary closure. Based on this we harvested FTSG instead of STSG from the ALT. METHODS: We retrospectively reviewed 10 cases of FTSG from the ALT, with the recipient site of foot in 3, ankle in 2, lower leg in 2, forearm in 2, and wrist in 1 patient...
December 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29063226/induced-granulation-tissue-but-not-artificial-dermis-enhances-early-host-graft-interactions-in-full-thickness-burn-wounds
#2
Heli Lagus, Esko Kankuri, Kristo Nuutila, Susanna Juteau, Maarit Sarlomo-Rikala, Jyrki Vuola
BACKGROUND: Cellular grafts used for skin repair require rapid integration with the host tissue to remain viable and especially to nourish the epidermal cells. Here, we evaluated the responses in the split-thickness skin grafts (STSGs) grafted on three differently treated wound beds: directly on excised wound bed (EX), on an artificial dermal template (DT) and on granulation tissue (GT) induced by cellulose sponge. METHODS: In ten burn patients, after excision, a test area was divided into three sections: One transplanted with STSG instantaneously and two sections had a pre-treatment for 2 weeks with either DT or a cellulose sponge inducing granulation tissue formation and thereafter grafted with STSGs...
October 23, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29049258/autologous-platelet-rich-plasma-thrombin-gel-combined-with-split-thickness-skin-graft-to-manage-postinfectious-skin-defects-a-randomized-controlled-study
#3
Barbara Hersant, Mounia SidAhmed-Mezi, Romain Bosc, Jean-Paul Meningaud
BACKGROUND: Managing cutaneous substance loss after debridement is challenging, especially if it is secondary to necrotizing soft tissue infection, such as necrotizing fasciitis and Fournier gangrene. After skin graft reconstruction, the healing process is longer and may be difficult, depending on the wound site, skin defect size, and patient comorbidities. OBJECTIVE: The aim of this study was to investigate whether autologous platelet-rich plasma (A-PRP) could accelerate and improve wound healing after cutaneous reconstruction for tissue loss secondary to soft tissue infection...
November 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28958281/an-innovative-way-to-separate-gastrointestinal-and-abdominal-wall-reconstruction-after-complex-abdominal-trauma
#4
David H Livingston, David V Feliciano
Despite advances in trauma care, a subset of patients surviving damage control cannot achieve fascial closure and require split-thickness skin grafting (STSG) of their open abdomen. Controversy exists as to whether reconstruction of the gastrointestine (GI) should be staged or performed at the time of abdominal wall reconstruction (AWR). Many surgeons do not believe that operations through the STSG can be completed safely or without loss of graft. This series reviews the outcomes of operations for GI reconstruction performed through the elevated healed STSG...
September 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28922518/accelerated-epithelialization-and-improved-wound-healing-metrics-in-porcine-full-thickness-wounds-transplanted-with-full-thickness-skin-micrografts
#5
Christina L Rettinger, John L Fletcher, Anders H Carlsson, Rodney K Chan
Split-thickness skin grafting (STSG) is the current gold standard for treatment of extensive burn and traumatic skin injuries. However, STSG is limited by donor-site morbidity and availability, and often leads to scarring and wound contracture. Furthermore, these thin grafts lack dermal elements such as nerves and adnexa which are important in recapitulating normal skin function. Methods of fractional skin replacement either as minced STSGs or microscopic skin tissue columns have been proposed, though these techniques have not been fully characterized and lack evidence of regenerated adnexal structures...
September 18, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28868232/penile-reconstruction-with-skin-grafts-and-dermal-matrices-indications-and-management
#6
Paloma Triana Junco, Mariela Dore, Vanesa Nuñez Cerezo, Javier Jimenez Gomez, Miriam Miguel Ferrero, Mercedes Díaz González, Pedro Lopez-Pereira, Juan Carlos Lopez-Gutierrez
Introduction  The penis eventually needs specific cutaneous coverage in the context of reconstructive procedures following trauma or congenital anomalies. Local flaps are the first choice but are not always available after multiple previous procedures. In these cases, skin graft and dermal matrices should be considered. Materials and Methods  This study was a retrospective review of the past 4 years of four patients with severe loss of penile shaft skin who underwent skin reconstruction. Dermal matrices and skin grafts were utilized...
January 2017: European Journal of Pediatric Surgery Reports
https://www.readbyqxmd.com/read/28862979/negative-pressure-wound-therapy-for-a-giant-wound-secondary-to-malignancy-induced-necrotizing-fasciitis-case-report-and-review-of-the-literature
#7
Jiayi Hu, Serge Goekjian, Nicolas Stone, Alexandra Nelson, Michael James Cooper
BACKGROUND: Necrotizing fasciitis (NF) is a life-threatening condition in which rapid diagnosis, debridement of nonviable tissue, and broad-spectrum antibiotics are critical to effective treatment. The debridement required can be extensive, resulting in large wounds that can sometimes be covered with split-thickness skin grafts (STSGs) with the help of negative pressure wound therapy (NPWT), or vacuum-assisted closure, to decrease the wound size. CASE REPORT: The authors report a rare case of NF due to malignancy-associated bowel perforation with a giant lower extremity wound secondary to debridement that involved 20% of the total body surface area (TBSA) in a 64-year-old, previously healthy, nonsmoking man...
August 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28801147/variability-in-split-thickness-skin-graft-depth-when-using-an-air-powered-dermatome-a-paediatric-cohort-study
#8
Craig A McBride, Margit Kempf, Roy M Kimble, Kellie Stockton
AIM: Split-thickness skin grafts (STSG) taken using calibrated powered dermatomes are assumed to yield a graft of uniform thickness, though this assumption has never been analysed statistically. This study aims to test that assumption in a paediatric population. METHOD: STSGs from a consecutive cohort of paediatric patients were analysed for mean thickness, measured from a central biopsy. All STSGs were taken from the thigh at a dialled thickness of 0.007in. Data were analysed using non-parametric methods...
November 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28797684/surgical-and-functional-outcomes-following-buried-penis-repair-with-limited-panniculectomy-and-split-thickness-skin-graft
#9
Lindsay A Hampson, Wade Muncey, Paul H Chung, C C Ma, Jeffrey Friedrich, Hunter Wessells, Bryan B Voelzke
OBJECTIVE: To report surgical and functional outcomes of buried penis surgery. METHODS: Outcomes following buried penis surgery at the University of Washington were assessed from June 1, 2005 to June 1, 2016. Patient demographic and surgical data were abstracted from a retrospective chart review. All patients were attempted to be contacted by phone for long-term follow-up. Uni- and multivariate analysis was performed to evaluate for association with any complication...
August 7, 2017: Urology
https://www.readbyqxmd.com/read/28795884/results-of-directly-applied-activated-carbon-cloth-in-chronic-wounds-a-preliminary-study
#10
H S Scheer, M Kaiser, U Zingg
OBJECTIVE: Activated carbon (AC) has been used in wound therapy as an active substance inside dressings. Applying AC directly on a wound is a new concept. The aim of this study was to analyse the outcomes of chronic wounds which were managed with directly applied activated carbon knitted cloth (ACC, Zorflex) in Swiss patients. METHOD: A retrospective analysis of the records of all patients with chronic wounds treated with ACC between 1 October 2013 and 31 December 2015 in an outpatient wound clinic...
August 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28779991/surgical-management-of-adult-acquired-buried-penis-escutcheonectomy-scrotectomy-and-penile-split-thickness-skin-graft
#11
Thomas W Fuller, Katherine Theisen, Paul Rusilko
OBJECTIVE: To demonstrate the surgical management of adult acquired buried penis (AABP). Affected patients have poor sexual function, urinary dribbling with subsequent skin breakdown, mood disturbance, lichen sclerosus with subsequent urethral stricture, and poor quality of life. Previous efforts have described limited repairs including an isolated resection of the escutcheon, which unfortunately often leads to reburying. We present a more extensive surgical repair including escutcheonectomy, scrotoplasty, and penile split-thickness skin graft (STSG) to provide a durable definitive repair...
October 2017: Urology
https://www.readbyqxmd.com/read/28727650/acquired-external-auditory-canal-atresia-a-comparison-of-acellular-dermal-matrix-and-split-thickness-skin-grafting-techniques
#12
Michel A Evans, Eric M Sugihara, Eleanor Y Chan
OBJECTIVE: To describe the use of acellular dermal matrix (ADM) in the repair of acquired external auditory canal atresia (AEACA), and compare surgical results to AEACA repair by split-thickness skin grafting (STSG). STUDY DESIGN: Retrospective chart review. SETTING: Neurotology clinical practice. PATIENTS AND INTERVENTION: From 2007 to 2015, 25 AEACA surgeries (8 ADM and 17 STSG) were identified meeting inclusion and exclusion criteria...
September 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28639977/topical-delivery-of-immunosuppression-to-prolong-xenogeneic-and-allogeneic-split-thickness-skin-graft-survival
#13
Melissa Mastroianni, Zhi Yang Ng, Ritu Goyal, Christopher Mallard, Evan A Farkash, David A Leonard, Alexander Albritton, Kumaran Shanmugarajah, Josef M Kurtz, David H Sachs, Lauren K Macri, Joachim Kohn, Curtis L Cetrulo
Cadaveric skin allograft is the current standard of treatment for temporary coverage of large burn wounds. Porcine xenografts are viable alternatives but undergo α-1,3-galactose (Gal)-mediated hyperacute rejection and are lost by POD 3 because of naturally occurring antibodies to Gal in primate recipients. Using baboons, we previously demonstrated that xenografts from GalT-KO swine (lacking Gal) provided wound coverage comparable with allografts with systemic immunosuppression. In this study, we investigate topical immunosuppression as an alternative to prolong xenograft survival...
June 7, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28615809/role-of-customised-negative-pressure-wound-therapy-in-the-integration-of-split-thickness-skin-grafts-a-randomised-control-study
#14
Mir Mohsin, Haroon Rashid Zargar, Adil Hafeez Wani, Mohammad Inam Zaroo, Peerzada Umar Farooq Baba, Sheikh Adil Bashir, Altaf Rasool, Akram Hussain Bijli
BACKGROUND: Split-thickness skin grafting (STSG) is a time-tested technique in wound cover, but many factors lead to suboptimal graft take. Role of custom-made negative-pressure wound therapy (NPWT) is compared with conventional dress in the integration of STSG and its cost is compared with widely used commercially available NPWT. MATERIALS AND METHODS: This is a parallel group randomised control study. Block randomisation of 100 patients into one of the two groups (NPWT vs...
January 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/28607863/immediate-regrafting-of-the-split-thickness-skin-graft-donor-site-assists-healing
#15
Brian P Bradow, Geoffrey G Hallock, Samuel P Wilcock
BACKGROUND: Delayed or even lack of healing of a split-thickness skin graft (STSG) donor site is a potential problem with elderly patients or those with poor wound healing capabilities. A proactive solution that may minimize this risk is to regraft that donor site using otherwise discarded skin graft remnants. METHODS: A prospective, nonrandomized, consecutive study was designed to compare the time to healing of the commonly used anterior thigh STSG donor site in patients who had routine dressings (n = 113) versus those with comorbidities known to adversely affect wound healing and had planned regrafting (n = 204)...
May 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28598907/treating-pain-on-skin-graft-donor-sites-review-and-clinical-recommendations
#16
REVIEW
Sarthak Sinha, Amanda J Schreiner, Jeff Biernaskie, Duncan Nickerson, Vincent A Gabriel
Split-thickness skin grafting is the most common reconstructive procedure in managing burn injuries. Harvesting split-thickness skin creates a new partial thickness wound referred to as the donor site. Pain at the donor site is reported to be one of the most distressing symptoms during the early postoperative period. Here, we (a) identify strategies for managing donor site pain, (b) assess the quality of individual studies, and (c) formulate evidence-based recommendations based on the amount and consistency of evidence...
November 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28598760/the-use-of-modern-dressings-in-managing-split-thickness-skin-graft-donor-sites-a-single-centre-randomised-controlled-trial
#17
M Kazanavičius, A Cepas, V Kolaityte, R Simoliuniene, R Rimdeika
OBJECTIVE: To identify the most appropriate, most suitable and most efficient dressing for split-thickness skin graft (STSG) donor sites. Comparing the wound healing rate, pain severity and duration, as well as the dressing change frequency in four randomised patient groups. METHODS: A single-centre non-blinded randomised controlled trial was carried out during 2010-2014. All patients treated for skin defects/lesions (due to burns, trauma or ulcers) using STSG were included in the study...
June 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28592936/grafting-both-acute-wound-site-and-adjacent-donor-site-with-the-same-graft-an-easy-and-safe-procedure-to-improve-healing-and-minimize-pain-in-elderly-and-bedridden-patients
#18
C Keilani, D Agard, A Duhoux, A Lakhel, O Giraud, M Brachet, P Duhamel, E Bey
In harvesting skin to cover the defect caused by a burn, a second wound is created, the donor site wound. We propose an alternative method to manage the donor site: taking a split-thickness skin graft (STSG) from a donor site adjacent to the burn wound to be treated, and meshing at a 3:1 ratio to cover both sites at once. The main objective of this study is to evaluate the effectiveness of covering both burn wound and adjacent donor site with the same STSG in elderly and bedridden patients. We retrospectively reviewed the medical records of 6 patients over 60 years old or/and bedridden presenting with a small burn wound who underwent STSG of both burn wound and adjacent donor site between April 2016 and November 2016 in the Department of Plastic Surgery and Burn Treatment at Percy Military Hospital (France)...
March 31, 2017: Annals of Burns and Fire Disasters
https://www.readbyqxmd.com/read/28526905/effectiveness-of-acellular-dermal-matrix-on-autologous-split-thickness-skin-graft-in-treatment-of-deep-tissue-defect-esthetic-subjective-and-objective-evaluation
#19
Yoo Jung Lee, Myong Chul Park, Dong Ha Park, Hyung Min Hahn, Sue Min Kim, Il Jae Lee
BACKGROUND: A split-thickness skin graft (STSG) is performed to cover a large full-thickness skin defect. Esthetic and functional deficits can result, and many studies have sought to overcome them. This study compared the effectiveness of the acellular dermal matrix (ADM) graft and STSG concerning esthetic and functional effectiveness of ADM on scar quality. METHODS: Of the patients who underwent anterolateral thigh free flap from 2011 to 2015, patients who received skin graft only (n = 10) or skin graft with ADM (n = 20) for coverage of the donor site were enrolled...
October 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28400148/accelerated-re-epithelialization-of-partial-thickness-skin-wounds-by-a-topical-betulin-gel-results-of-a-randomized-phase-iii-clinical-trials-program
#20
Juan P Barret, Fred Podmelle, Břetislav Lipový, Hans-Oliver Rennekampff, Hauke Schumann, Agnes Schwieger-Briel, Tobias R Zahn, Hans-Robert Metelmann
The clinical significance of timely re-epithelialization is obvious in burn care, since delayed wound closure is enhancing the risk of wound site infection and extensive scarring. Topical treatments that accelerate wound healing are urgently needed to reduce these sequelae. Evidence from preliminary studies suggests that betulin can accelerate the healing of different types of wounds, including second degree burns and split-thickness skin graft wounds. The goal of this combined study program consisting of two randomized phase III clinical trials in parallel is to evaluate whether a topical betulin gel (TBG) is accelerating re-epithelialization of split-thickness skin graft (STSG) donor site wounds compared to standard of care...
April 8, 2017: Burns: Journal of the International Society for Burn Injuries
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