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Tooth transplant

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https://www.readbyqxmd.com/read/28544606/effects-of-tooth-storage-media-on-periodontal-ligament-preservation
#1
Md Riasat Hasan, Hiroaki Takebe, Nazmus Shalehin, Nobuko Obara, Takashi Saito, Kazuharu Irie
BACKGROUND / AIMS: An easily available tooth storage medium is required to preserve a tooth after avulsion. Milk and Hank's balanced salt solution (HBSS) are recommended as tooth storage media, and egg white is also reported to be comparable with milk. The aim of the present study was to histologically and immunohistochemically evaluate the effect of different tooth storage media on the periodontal ligament (PDL) of extracted teeth. MATERIAL AND METHODS: This experiment used HBSS, milk and egg white as tooth storage media...
May 24, 2017: Dental Traumatology: Official Publication of International Association for Dental Traumatology
https://www.readbyqxmd.com/read/28541773/induction-of-salivary-gland-like-cells-from-dental-follicle-epithelial-cells
#2
Q L Xu, A Furuhashi, Q Z Zhang, C M Jiang, T-H Chang, A D Le
The dental follicle (DF), most often associated with unerupted teeth, is a condensation of ectomesenchymal cells that surrounds the tooth germ in early stages of tooth development. In the present study, we aim to isolate epithelial stem-like cells from the human DF and explore their potential differentiation into salivary gland (SG) cells. We demonstrated the expression of stem cell-related genes in the epithelial components of human DF tissues, and these epithelial progenitor cells could be isolated and ex vivo expanded in a reproducible manner...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28529149/autotransplantation-of-third-molars-with-platelet-rich-plasma-for-immediate-replacement-of-extracted-non-restorable-teeth-a-case-series
#3
Jorge Gonzalez-Ocasio, Mark Stevens
PURPOSE: The aim of this study was to examine the use of platelet-rich plasma (PRP) for autotransplantation of third molars as a successful technique to provide immediate tooth structure for space maintenance and masticatory function when premature loss of a permanent tooth occurs and other dental restorative options are not indicated. MATERIALS AND METHODS: This study included 10 healthy patients 10 to 17 years of age with at least 1 immature third molar (one to two thirds of root formation) used to replace extracted non-restorable teeth...
April 25, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28512542/cambra-system-in-patients-awaiting-hematopoietic-progenitor-cell-transplant-and-high-caries-risk
#4
Ana Hernández-Fernández, Antonio-José Ortiz-Ruiz, Felipe De Arriba-de la Fuente, Vicente Vicente-García, Pastora Iniesta-López-Matencio, Ricardo-Elias Oñate-Sánchez
BACKGROUND: Recent times have witnessed a significant increase in the number of patients affected by problems related to oncological treatment Aims of this study is to evaluate dental affectation among patients awaiting hematopoietic progenitor cell transplant (HPCT), and they showed high caries risk, so it should establish a protocol prior to transplantation. MATERIAL AND METHODS: The study included 72 patients due for HPCT. Clinical and radiological explorations were performed and oral photos taken...
May 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28497078/joubert-syndrome-misleading-presentation-of-two-cases-as-pseudo-tumor-cerebri-and-literature-review
#5
Farrokh Seylanian Toosi, Samineh Boloursaz, Bita Abbasi, Reza Hekmat, Reihaneh Mortazavi Ardestani, Mina Mohajerzadeh
Joubert syndrome is a rare autosomal recessive disorder that may have different clinical presentation such as ataxia, hyperpnea, sleep apnea, nystagmus, hypotonia, seizure and retinitis pigmentosa. We present a 22-year-old girl and her older sibling, labeled as cerebral palsy. She had renal transplant years ago without the true diagnosis of the disorder. Brain imaging revealed the classic "molar tooth sign" appearance, and clinical evaluation established the diagnosis for both of the siblings. Imaging should be done to evaluate the neuroradiological findings of Joubert syndrome...
2017: Journal of Renal Injury Prevention
https://www.readbyqxmd.com/read/28478868/autotransplantation-of-teeth-using-computer-aided-rapid-prototyping-of-a-three-dimensional-replica-of-the-donor-tooth-a-systematic-literature-review
#6
REVIEW
J P Verweij, F A Jongkees, D Anssari Moin, D Wismeijer, J P R van Merkesteyn
This systematic review provides an overview of studies on autotransplantation techniques using rapid prototyping for preoperative fabrication of donor tooth replicas for preparation of the neo-alveolus. Different three-dimensional autotransplantation techniques and their treatment outcomes are discussed. The systematic literature search yielded 19 articles that satisfied the criteria for inclusion. These papers described one case-control study, four clinical observational studies, one study with a clinical and in vitro part, four in vitro studies, and nine case reports...
May 3, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28462188/the-role-of-nuclear-factor-i-c-in-tooth-and-bone-development
#7
REVIEW
Song Yi Roh, Joo-Cheol Park
Nuclear factor I-C (NFI-C) plays a pivotal role in various cellular processes such as odontoblast and osteoblast differentiation. Nfic-deficient mice showed abnormal tooth and bone formation. The transplantation of Nfic-expressing mouse bone marrow stromal cells rescued the impaired bone formation in Nfic(-/-) mice. Studies suggest that NFI-C regulate osteogenesis and dentinogenesis in concert with several factors including transforming growth factor-β1, Krüppel-like factor 4, and β-catenin. This review will focus on the function of NFI-C during tooth and bone formation and on the relevant pathways that involve NFI-C...
April 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/28453949/replacing-heavily-damaged-teeth-by-third-molar-autotransplantation-with-the-use-of-cone-beam-computed-tomography-and-rapid-prototyping
#8
J P Verweij, D Anssari Moin, D Wismeijer, J P R van Merkesteyn
This article describes the autotransplantation of third molars to replace heavily damaged premolars and molars. Specifically, this article reports on the use of preoperative cone-beam computed tomographic planning and 3-dimensional (3D) printed replicas of donor teeth to prepare artificial tooth sockets. In the present case, an 18-year-old patient underwent autotransplantation of 3 third molars to replace 1 premolar and 2 molars that were heavily damaged after trauma. Approximately 1 year after the traumatic incident, autotransplantation with the help of 3D planning and rapid prototyping was performed...
April 4, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28412234/premolar-autotransplantation-in-juvenile-dentition-quantitative-assessment-of-vertical-bone-and-soft-tissue-growth
#9
Inessa Michl, Dirk Nolte, Claudia Tschammler, Martin Kunkel, Robert Linsenmann, Johannes Angermair
OBJECTIVE: Premolar autotransplantation represents an effective therapeutic option for the treatment of juvenile dentition with either aquired or congenital hypodontia. The objective of this prospective clinical study was to quantitatively assess bone and soft tissue levels after autogenous premolar transplantation by clinical and radiographic parameters. STUDY DESIGN: In the study, 26 premolars were transplanted in 20 patients after traumatic tooth loss (n = 16) or congenital aplasia (n = 10) in the anterior maxilla...
February 22, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28381733/tooth-auto-transplantation-an-alternative-treatment
#10
Jawaad Ahmed Asif, Tahir Yusuf Noorani, Mohammad Khursheed Alam
Auto-transplantation is the repositioning of an autogenously erupted, partially erupted, or unerupted tooth from one site to another in the same individual. The purpose of this case report is to describe the auto-transplantation of the mandibular third molars as an alternative means of replacing second molars requiring extraction. An orthopantomogram revealed horizontal impaction of teeth #37 and 47 and mesio-angular impaction of teeth #38 and 48. Cone beam computed tomography revealed that the roots of #37 and 47 were in close proximity to the inferior alveolar canal bilaterally...
2017: Bulletin of Tokyo Dental College
https://www.readbyqxmd.com/read/28331230/dentin-sialoprotein-facilitates-dental-mesenchymal-cell-differentiation-and-dentin-formation
#11
Wentong Li, Lei Chen, Zhuo Chen, Lian Wu, Junsheng Feng, Feng Wang, Lisa Shoff, Xin Li, Kevin J Donly, Mary MacDougall, Shuo Chen
Dentin sialoprotein (DSP) is a dentin extracellular matrix protein. It is involved in dental mesenchymal cell lineages and dentin formation through regulation of its target gene expression. DSP mutations cause dentin genetic diseases. However, mechanisms of DSP in controlling dental mesenchymal cell differentiation are unknown. Using DSP as bait, we screened a protein library from mouse odontoblastic cells and found that DSP is a ligand and binds to cell surface receptor, occludin. Further study identified that the C-terminal DSP domain(aa 363-458) interacts with the occludin extracellular loop 2(aa 194-241)...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28317353/-clinical-application-on-restoration-of-dentition-defects-using-tooth-alveolar-bone-grafts
#12
Chen Zhifang, Zhang Wei
OBJECTIVE: To evaluate the clinical effectiveness of tooth-alveolar bone grafts in repairing dentition defects. METHODS: Forty-five patients with dentition defect were divided into two groups according to different operation methods. In group A (n=24), the tooth-alveolar bone grafts of the transplanted tooth and its surrounding alveolar bone were cut using modified surgical orthodontics and then embedded into the designated planting hole. In group B (n=21), the teeth were extracted through conventional tooth transplantation and then embedded into the prepared planting holes...
August 1, 2016: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/28300208/practical-whole-tooth-restoration-utilizing-autologous-bioengineered-tooth-germ-transplantation-in-a-postnatal-canine-model
#13
Mitsuaki Ono, Masamitsu Oshima, Miho Ogawa, Wataru Sonoyama, Emilio Satoshi Hara, Yasutaka Oida, Shigehiko Shinkawa, Ryu Nakajima, Atsushi Mine, Satoru Hayano, Satoshi Fukumoto, Shohei Kasugai, Akira Yamaguchi, Takashi Tsuji, Takuo Kuboki
Whole-organ regeneration has great potential for the replacement of dysfunctional organs through the reconstruction of a fully functional bioengineered organ using three-dimensional cell manipulation in vitro. Recently, many basic studies of whole-tooth replacement using three-dimensional cell manipulation have been conducted in a mouse model. Further evidence of the practical application to human medicine is required to demonstrate tooth restoration by reconstructing bioengineered tooth germ using a postnatal large-animal model...
March 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28286291/human-%C3%AE-defensin-2-and-interleukin-1%C3%AE-expression-in-response-to-porphyromonas-gingivalis-challenge-in-mice-transplanted-with-periodontitic-human-gingiva
#14
Tomoko Shimizu, Masahiro To, Yohei Kamata, Juri Saruta, Takenori Sato, Shinya Fuchida, Nobushiro Hamada, Keiichi Tsukinoki
Inter-individual variability in the host response contributes significantly to expression of periodontal disease. Thus, research into the human host response is considered important in the analysis of periodontal disease. Human β-defensin-2 (hBD-2) is typically produced by epithelial tissues after stimulation with microorganisms and inflammatory mediators, and it contributes to the initial defense in the innate immune response. However, hBD-2 expression in response to infection has not been investigated in human gingival tissue with periodontitis...
March 9, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28224037/tooth-extraction-in-a-patient-after-autologous-skeletal-myoblast-sheet-transplantation-for-severe-dilated-cardiomyopathy
#15
Kohei Okuyama, Yuki Sakamoto, Tomofumi Naruse, Souichi Yanamoto, Masahiro Umeda
The authors describe the first case of tooth extraction in a patient treated with autologous skeletal myocardial sheet transplantation for severe dilated cardiomyopathy. This condition is associated with significant morbidity and mortality that may have identifiable causes or may be idiopathic or inherited. In addition to local disinfection, antimicrobial prophylaxis and continuous anticoagulant therapy during the perioperative period of tooth extraction were needed to prevent infective endocarditis and ensure the success of regenerative therapy of the heart...
March 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28217369/regenerative-medicine-using-dental-pulp-stem-cells-for-liver-diseases
#16
EDITORIAL
Shogo Ohkoshi, Hajime Hara, Haruka Hirono, Kazuhiko Watanabe, Katsuhiko Hasegawa
Acute liver failure is a refractory disease and its prognosis, if not treated using liver transplantation, is extremely poor. It is a good candidate for regenerative medicine, where stem cell-based therapies play a central role. Mesenchymal stem cells (MSCs) are known to differentiate into multiple cell lineages including hepatocytes. Autologous cell transplant without any foreign gene induction is feasible using MSCs, thereby avoiding possible risks of tumorigenesis and immune rejection. Dental pulp also contains an MSC population that differentiates into hepatocytes...
February 6, 2017: World Journal of Gastrointestinal Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28185382/autogenous-bone-block-grafting-provides-facial-implant-tissue-stability-long-term
#17
Fernando Verdugo, Agurne Uribarri, Antonio D'Addona
BACKGROUND: Mucosal recession (MR) and bone loss can compromise anterior implant esthetics. PURPOSE: To evaluate tissue stability and clinical outcomes of anterior implants augmented with autogenous block transplants long-term. MATERIALS AND METHODS: This prospective cross-sectional clinical study analyzed facial tissue recession of anterior implants augmented with autogenous bone blocks and compared them to adjacent teeth in forty patients 52 months post-augmentation...
February 10, 2017: Clinical Implant Dentistry and related Research
https://www.readbyqxmd.com/read/28179939/autogenous-transplantation-for-replacing-a-hopeless-tooth
#18
Mehrsa Zakershahrak, Amirabbas Moshari, Mehdi Vatanpour, Zohreh Khalilak, Afsoon Jalali Ara
Autogenous tooth transplantation (ATT) is a simple and reasonable choice for replacing the missing teeth when a proper donor tooth is available. This report presents a case of successful ATT of a maxillary right third molar for replacement of mandibular right second molar with a concomitant endodontic-periodontal disease. The mandibular second molar was believed to be hopeless due to a severe damage to coronal tooth structure, inappropriate root canal treatment and apical radiolucency. After extraction of mandibular second molar and maxillary third molar (the donor), the tooth was re-implanted into the extracted socket of second molar site...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28177531/recruitment-of-bone-marrow-derived-cells-to-the-periodontal-ligament-via-the-stromal-cell-derived-factor-1-c-x-c-chemokine-receptor-type-4-axis
#19
M Kaku, M Kitami, J M Rosales Rocabado, T Ida, Y Akiba, K Uoshima
BACKGROUND/OBJECTIVES: The periodontal ligament (PDL) is a non-mineralized connective tissue that exists between the alveolar bone and root surface cementum and plays important roles in tooth function. The PDL harbors a remarkable reserve of multipotent stem cells, which maintain various types of cells. However, the sources of these stem cells, other than their developmental origin, are not well understood. MATERIAL AND METHODS: To elucidate the recruitment of bone marrow (BM)-derived stem cells in the PDL, green fluorescent protein (GFP)-expressing BM-derived cells were transplanted into the femoral BM of immunodeficient rats, and the distribution and expression of stem cell markers in the PDL were analyzed in vivo...
February 8, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28168900/a-translational-medicine-approach-to-tooth-transplantation
#20
Giovanpaolo Pini Prato, Giliana Zuccati, Carlo Clauser
No abstract text is available yet for this article.
February 7, 2017: Journal of Periodontology
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