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https://www.readbyqxmd.com/read/27909542/which-factors-influence-resident-physicians-to-prescribe-noacs-to-patients-with-non-valvular-atrial-fibrillation
#1
Zardasht Oqab Md Frcpc, William F McIntyre Md Frcpc, Wilma M Hopman Ma, Adrian Baranchuk Md Facc Frcp
The Canadian Cardiovascular Society and the European Society of Cardiology recommend the use of non-vitamin K antagonists (NOAC) in preference to warfarin for stroke prevention in most patients with non-valvular atrial fibrillation (AF). The aim of this study was to identify factors that predict selection of a NOAC by resident physicians when faced with patients with non-valvular AF. A web-based survey was distributed to residents across Canada to learn the attitudes and behaviours regarding stroke, bleeding risk and choices of therapy in different clinical scenarios involving the same patient and one additional co-morbidity...
August 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27880009/antianginal-efficacy-of-ivabradine-metoprolol-combination-in-patients-with-stable-angina
#2
John Zarifis, Manolis Kallistratos, Apostolos Katsivas
Medical treatment is the main clinical strategy for controlling patients with chronic stable angina and improving their quality of life (QoL). Ivabradine treatment on top of metoprolol decreases angina symptoms and improves QoL in patients with stable angina and coronary artery disease (CAD). This is a post hoc analysis (636 CAD patients given ivabradine/metoprolol free combination) of a prospective, noninterventional study that included 2403 patients with CAD and stable angina. Data were recorded at baseline at 1 and 4 months after inclusion...
November 23, 2016: Clinical Cardiology
https://www.readbyqxmd.com/read/27875377/spinal-cord-stimulation-for-refractory-angina-pectoris-a-systematic-review-and-meta-analysis
#3
Xiaoxiao Pan, Hongguang Bao, Yanna Si, Chenjie Xu, Hao Chen, Xianzhong Gao, Xinyi Xie, Yajie Xu, Fan Sun, Lingqing Zeng
OBJECTIVES: Parasthesia free stimulation, such as high frequency and burst have been demonstrated as effective therapies for neuropathic pain. The aim of this meta-analysis was to evaluate the efficacy and safety of conventional spinal cord stimulation (SCS) in the treatment of refractory angina pectoris (RAP). METHODS: Relevant randomized controlled trial (RCT) studies that investigated SCS for patients with RAP were comprehensively searched in Medline, Pubmed, Embase, and Cochrane Library...
November 21, 2016: Clinical Journal of Pain
https://www.readbyqxmd.com/read/27865641/canadian-cardiovascular-society-guidelines-on-perioperative-cardiac-risk-assessment-and-management-for-patients-who-undergo-noncardiac-surgery
#4
Emmanuelle Duceppe, Joel Parlow, Paul MacDonald, Kristin Lyons, Michael McMullen, Sadeesh Srinathan, Michelle Graham, Vikas Tandon, Kim Styles, Amal Bessissow, Daniel I Sessler, Gregory Bryson, P J Devereaux
The Canadian Cardiovascular Society Guidelines Committee and key Canadian opinion leaders believed there was a need for up to date guidelines that used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system of evidence assessment for patients who undergo noncardiac surgery. Strong recommendations included: 1) measuring brain natriuretic peptide (BNP) or N-terminal fragment of proBNP (NT-proBNP) before surgery to enhance perioperative cardiac risk estimation in patients who are 65 years of age or older, are 45-64 years of age with significant cardiovascular disease, or have a Revised Cardiac Risk Index score ≥ 1; 2) against performing preoperative resting echocardiography, coronary computed tomography angiography, exercise or cardiopulmonary exercise testing, or pharmacological stress echocardiography or radionuclide imaging to enhance perioperative cardiac risk estimation; 3) against the initiation or continuation of acetylsalicylic acid for the prevention of perioperative cardiac events, except in patients with a recent coronary artery stent or who will undergo carotid endarterectomy; 4) against α2 agonist or β-blocker initiation within 24 hours before surgery; 5) withholding angiotensin-converting enzyme inhibitor and angiotensin II receptor blocker starting 24 hours before surgery; 6) facilitating smoking cessation before surgery; 7) measuring daily troponin for 48 to 72 hours after surgery in patients with an elevated NT-proBNP/BNP measurement before surgery or if there is no NT-proBNP/BNP measurement before surgery, in those who have a Revised Cardiac Risk Index score ≥1, age 45-64 years with significant cardiovascular disease, or age 65 years or older; and 8) initiating of long-term acetylsalicylic acid and statin therapy in patients who suffer myocardial injury/infarction after surgery...
October 4, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27760636/-safety-and-efficacy-of-off-pump-coronary-artery-bypass-grafting-in-octogenarians
#5
T S Liu, B T Chen, R Dong, Y Li, Y Zhao, K Hua
Objective: To discuss the clinical safety and efficacy about off-pump coronary artery bypass grafting (OPCABG) in octogenarians. Methods: From June 2005 to July 2014, 252 patients (male 208, female 44, with a mean age of 81.7 years old) underwent OPCABG in Beijing Anzhen Hospital who were aged 80 years or older were enrolled. Results: Eight (3.2%) patients were diagnosed as single vessel coronary artery disease (CAD), 29 cases (11.5%) were diagnosed as bifurcation vessel CAD, and 215 cases (85.3%) were multivessel CAD...
September 27, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27743759/quality-of-care-for-percutaneous-coronary-intervention-development-of-canadian-cardiovascular-society-quality-indicators
#6
Ata Ur Rehman Quraishi, Laurie J Lambert, Mina Madan, Yanyan Gong, Anne Forsey, Diane Galbraith, Neala Gill, Garth H Oakes, Andrea Lavoie, Ronald G Carere, Robert C Welsh
Currently there are more than 40 centres in Canada that perform more than 65,000 percutaneous coronary interventions (PCIs) in a year. Considering the high volume of procedures and number of operators, the potential for variation in processes of care is high, and might lead to variation in the quality of care. As part of its quality initiative, the Canadian Cardiovascular Society convened a working group to develop a set of PCI Quality Indicators (QIs) that would be relevant, scientifically acceptable, and feasible to measure and report...
July 25, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27712954/2016-canadian-cardiovascular-society-guidelines-for-the-management-of-dyslipidemia-for-the-prevention-of-cardiovascular-disease-in-the-adult
#7
Todd J Anderson, Jean Grégoire, Glen J Pearson, Arden R Barry, Patrick Couture, Martin Dawes, Gordon A Francis, Jacques Genest, Steven Grover, Milan Gupta, Robert A Hegele, David C Lau, Lawrence A Leiter, Eva Lonn, G B John Mancini, Ruth McPherson, Daniel Ngui, Paul Poirier, John L Sievenpiper, James A Stone, George Thanassoulis, Richard Ward
Since the publication of the 2012 guidelines new literature has emerged to inform decision-making. The 2016 guidelines primary panel selected a number of clinically relevant questions and has produced updated recommendations, on the basis of important new findings. In subjects with clinical atherosclerosis, abdominal aortic aneurysm, most subjects with diabetes or chronic kidney disease, and those with low-density lipoprotein cholesterol ≥ 5 mmol/L, statin therapy is recommended. For all others, there is an emphasis on risk assessment linked to lipid determination to optimize decision-making...
July 25, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27703034/clinical-impact-of-subsequent-depression-in-patients-with-a-new-diagnosis-of-stable-angina-a-population-based-study
#8
Natalie Szpakowski, Maria C Bennell, Feng Qiu, Dennis T Ko, Jack V Tu, Paul Kurdyak, Harindra C Wijeysundera
BACKGROUND: Depression is prevalent among patients with myocardial infarction and is associated with a worse prognosis. However, little is known about its importance in patients with chronic stable angina. We conducted a retrospective population-based cohort study to determine the occurrence and predictors of developing depression in patients with a new diagnosis of chronic stable angina. In addition, we sought to understand its impact on subsequent clinical outcomes. METHODS AND RESULTS: Our cohort included patients in Ontario, Canada, with stable angina based on obstructive coronary artery disease found on angiogram...
October 4, 2016: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/27692116/ensuring-cardiac-rehabilitation-access-for-the-majority-of-those-in-need-a-call-to-action-for-canada
#9
Sherry L Grace, Karam Turk-Adawi, Carolina Santiago de Araújo Pio, David A Alter
Cardiac rehabilitation (CR) is a proven model of secondary prevention. Indicated cardiac conditions for CR are well established, and participation of these patients results in significantly lower mortality and morbidity when compared with usual care. There are approximately 170 CR programs in Canada, which varies widely by province. There is a grossly insufficient capacity to treat all patients with cardiac indications in Canada and beyond. The density of CR services is about half that in the United States, at 1 program per 208,823 inhabitants or 1 program per 7779 patients with cardiac disease...
October 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27609430/2016-focused-update-of-the-canadian-cardiovascular-society-guidelines-for-the-management-of-atrial-fibrillation
#10
Laurent Macle, John Cairns, Kori Leblanc, Teresa Tsang, Allan Skanes, Jafna L Cox, Jeff S Healey, Alan Bell, Louise Pilote, Jason G Andrade, L Brent Mitchell, Clare Atzema, David Gladstone, Mike Sharma, Subodh Verma, Stuart Connolly, Paul Dorian, Ratika Parkash, Mario Talajic, Stanley Nattel, Atul Verma
The Canadian Cardiovascular Society (CCS) Atrial Fibrillation (AF) Guidelines Committee provides periodic reviews of new data to produce focused updates that address clinically important advances in AF management. This 2016 Focused Update deals with: (1) the management of antithrombotic therapy for AF patients in the context of the various clinical presentations of coronary artery disease; (2) real-life data with non-vitamin K antagonist oral anticoagulants; (3) the use of antidotes for the reversal of non-vitamin K antagonist oral anticoagulants; (4) digoxin as a rate control agent; (5) perioperative anticoagulation management; and (6) AF surgical therapy including the prevention and treatment of AF after cardiac surgery...
October 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27592324/there-is-no-association-between-the-omega-3-index-and-depressive-symptoms-in-patients-with-heart-disease-who-are-low-fish-consumers
#11
Shaoxin Cai, Alison M Coates, Jonathan D Buckley, Narelle M Berry, Lisa Burres, John Beltrame, Peter R C Howe, Geoffrey Schrader
BACKGROUND: Long chain Omega-3 polyunsaturated fatty acids (LCn3PUFAs) may improve cardiovascular health and depression. This study investigated the relationships between erythrocyte membrane LCn3PUFA status, depression and angina symptoms in patients with heart disease. METHODS: We recruited 91 patients (65 males and 26 females, mean age 59.2±10.3 years) with heart disease and depressive symptoms (Center for Epidemiological Studies Depression Scale, CES-D ≥ 16) and low fish/fish oil intakes...
August 16, 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27591692/rotational-atherectomy-of-three-overlapping-stent-layers
#12
Tiberio M Frisoli, Harold Friedman, William W O'Neill
A patient was referred to us for Canadian Cardiovascular Society class III refractory angina. He was found to have in-stent restenosis within three layers of underexpanded stents implanted in 2004, 2011, and 2014. Rotational atherectomy safely yielded stent strut ablation (reduced to one layer), lesion expansion, and very good angiographic and physiologic results.
September 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27475811/short-term-cardioprotective-effects-of-the-original-perindopril-amlodipine-fixed-dose-combination-in-patients-with-stable-coronary-artery-disease-results-of-the-papa-cad-study
#13
Tamás Forster, Csaba András Dézsi
INTRODUCTION: Long-term therapy with a combination of perindopril and amlodipine has shown a beneficial effect on the morbidity and mortality of patients with stable coronary artery disease (SCAD) and hypertension. On the basis of the antiproliferative, antithrombotic, and antiatherogenic effects of the active substances, we initiated data collection to examine the short-term cardioprotective effect of perindopril/amlodipine fixed-dose combination therapy in this patient group. The aim of this study was to evaluate the effect of perindopril/amlodipine fixed-dose combination on the Canadian Cardiovascular Society (CCS) class and exercise capacity of patients with SCAD in everyday medical practice...
October 2016: Advances in Therapy
https://www.readbyqxmd.com/read/27432382/effectiveness-and-tolerability-of-ivabradine-with-or-without-concomitant-beta-blocker-therapy-in-patients-with-chronic-stable-angina-in-routine-clinical-practice
#14
Stefan Perings, Georg Stöckl, Malte Kelm
INTRODUCTION: In the prospective, open-label, non-interventional, multicenter RESPONSIfVE study, the effectiveness, response rates and tolerability of ivabradine with or without beta blocker (BB) were evaluated in patients with chronic stable angina pectoris (AP) in daily clinical practice. METHODS: In patients with AP, ivabradine was given twice daily in flexible doses for 4 months. Resting heart rate (HR), number of angina attacks, short-acting nitrate use, severity of symptoms [by Canadian Cardiovascular Society (CCS) score] and tolerability with or without existing BB therapy were documented and analyzed using descriptive statistical methods...
September 2016: Advances in Therapy
https://www.readbyqxmd.com/read/27343741/canadian-cardiovascular-society-guidelines-for-evaluation-and-management-of-cardiovascular-complications-of-cancer-therapy
#15
Sean A Virani, Susan Dent, Christine Brezden-Masley, Brian Clarke, Margot K Davis, Davinder S Jassal, Christopher Johnson, Julie Lemieux, Ian Paterson, Igal A Sebag, Christine Simmons, Jeffrey Sulpher, Kishore Thain, Paaldinesh Thavendiranathan, Jason R Wentzell, Nola Wurtele, Marc André Côté, Nowell M Fine, Haissam Haddad, Bradley D Hayley, Sean Hopkins, Anil A Joy, Daniel Rayson, Ellamae Stadnick, Lynn Straatman
Modern treatment strategies have led to improvements in cancer survival, however, these gains might be offset by the potential negative effect of cancer therapy on cardiovascular health. Cardiotoxicity is now recognized as a leading cause of long-term morbidity and mortality among cancer survivors. This guideline, authored by a pan-Canadian expert group of health care providers and commissioned by the Canadian Cardiovascular Society, is intended to guide the care of cancer patients with established cardiovascular disease or those at risk of experiencing toxicities related to cancer treatment...
July 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27307471/the-anticoagulation-choices-of-internal-medicine-residents-for-stroke-prevention-in-non-valvular-atrial-fibrillation
#16
Nathaniel Moulson, William F McIntyre, Zardasht Oqab, Payam Yazdan-Ashoori, Kieran L Quinn, Erik van Oosten, Wilma M Hopman, Adrian Baranchuk
PURPOSE OF THE STUDY: To explore the oral anticoagulation (OAC) prescribing choices of Canadian internal medicine residents, at different training levels, in comparison with the Canadian Cardiovascular Society (CCS) guidelines for non-valvular atrial fibrillation (NVAF). STUDY DESIGN: Cross-sectional, web-based survey, involving clinical scenarios designed to favour the use of non-vitamin K antagonists (NOACs) as per the 2014 CCS NVAF guidelines. Additional questions were also designed to determine resident attitudes towards OAC prescribing...
June 15, 2016: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/27297003/the-development-and-feasibility-assessment-of-canadian-quality-indicators-for-atrial-fibrillation
#17
Jafna L Cox, Sulan Dai, Yanyan Gong, Robert McKelvie, M Sean McMurtry, Garth H Oakes, Allan Skanes, Atul Verma, Stephen B Wilton, D George Wyse
In 2010, the Canadian Cardiovascular Society embarked on an initiative to develop pan-Canadian quality indicators (QIs) and standardized data definitions with the ultimate goal of monitoring, comparing, and contrasting national cardiovascular care and its outcomes. One of the first working groups to be established was tasked with identifying and then defining a set of QIs for atrial fibrillation/flutter (AF/AFL). The Canadian Cardiovascular Society "Best Practices for Developing Cardiovascular Quality Indicators" methodology was used to develop an initial catalogue of 25 QIs intended to measure critical issues around access, process, and outcomes relating to AF/AFL management...
February 27, 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27233892/canadian-cardiovascular-society-canadian-society-of-cardiac-surgeons-canadian-society-for-vascular-surgery-joint-position-statement-on-open-and-endovascular-surgery-for-thoracic-aortic-disease
#18
Jehangir J Appoo, John Bozinovski, Michael W A Chu, Ismail El-Hamamsy, Thomas L Forbes, Michael Moon, Maral Ouzounian, Mark D Peterson, Jacques Tittley, Munir Boodhwani
In 2014, the Canadian Cardiovascular Society (CCS) published a position statement on the management of thoracic aortic disease addressing size thresholds for surgery, imaging modalities, medical therapy, and genetics. It did not address issues related to surgical intervention. This joint Position Statement on behalf of the CCS, Canadian Society of Cardiac Surgeons, and the Canadian Society for Vascular Surgery provides recommendations about thoracic aortic disease interventions, including: aortic valve repair, perfusion strategies for arch repair, extended arch hybrid reconstruction for acute type A dissection, endovascular management of arch and descending aortic aneurysms, and type B dissection...
June 2016: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/27119029/solid-right-ventricular-compression-by-intraventricular-septum-hematoma-induced-after-percutaneous-coronary-intervention
#19
Ibrahim El-Battrawy, Ibrahim Akin, Benedikt Münz, David Manuel Leistner, Michael Behnes, Thomas Henzler, Holger Haubenreisser, Theano Papavassiliu, Martin Borggrefe, Ralf Lehmann
Intraventricular septum-hematoma is a rare complication following percutaneous coronary intervention (PCI). This complication may represent a challenge for accurate diagnosis and treatment. This case report is about a 60-year-old male patient being admitted with an acute coronary syndrome. Despite successful PCI with drug eluting stent implantation into the right coronary artery (RCA) the patient complained about recurrent angina pectoris according to Canadian Cardiovascular Society (CCS) class IV. Cardiac magnetic resonance imaging and transthoracic echocardiography revealed a massive 4...
2016: Case Reports in Cardiology
https://www.readbyqxmd.com/read/27055955/a-lipidologist-perspective-of-global-lipid-guidelines-and-recommendations-part-2-lipid-treatment-goals
#20
REVIEW
Harold E Bays
Having knowledge of worldwide areas of harmonization and consensus regarding lipid guidelines and recommendations may provide clinicians a more global perspective on lipid management. This review examines 8 international scientific/medical organizations that have issued lipid guidelines, recommendations, and position papers: the National Lipid Association (2014), National Institute for Health and Care Excellence (2014), International Atherosclerosis Society (2013), American College of Cardiology/American Heart Association (2013), Canadian Cardiovascular Society (2013), Japan Atherosclerosis Society (2012), European Society of Cardiology/European Atherosclerosis Society (2012), and Adult Treatment Panel III (2001/2004)...
March 2016: Journal of Clinical Lipidology
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