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https://www.readbyqxmd.com/read/29458138/pharmacokinetic-and-pharmacodynamic-evaluation-of-5-methoxy-2-aminoindane-meai-a-new-binge-mitigating-agent
#1
Jakob A Shimshoni, Eyal Sobol, Ezekiel Golan, Yulius Ben Ari, Orit Gal
5-Methoxy-2-aminoindane (MEAI) is a novel psychoactive aminoindane derivative, exerting euphoric, alcohol-like tipsy experience and reduced desire to consume alcoholic beverages. Our previous toxicological evaluation of MEAI in rats, clearly indicated MEAI's potential to be further evaluated as a promising binge mitigating agent due to its favorable safety profile. In the light of these observations, we have determined MEAI's pharmacokinetic (PK) profile in rats and evaluated in-vitro its pharmacodynamics (PD) profile...
February 16, 2018: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/29458115/effect-of-acek-acesulfame-potassium-on-brain-function-under-dietary-restriction-in-mice
#2
Daisuke Ibi, Fumika Suzuki, Masayuki Hiramatsu
People preferably take zero or low-calorie beverages and foods with artificial sweeteners even though it has been recently suggested that long-term artificial sweetener use affects physiological functions. In addition, a lower body weight was considered to be more healthful, but an abnormally low body weight caused by an excessive diet has been reported to cause health problems. Acesulfame potassium (AceK) is one of the most commonly used for foods and beverages because of its resistance to thermal degradation and marked sweetness...
February 16, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29457580/food-and-beverage-intakes-according-to-physical-activity-levels-in-european-children-the-idefics-identification-and-prevention-of-dietary-and-lifestyle-induced-health-effects-in-children-and-infants-study
#3
Alba M Santaliestra-Pasías, Jaime E Llamas Dios, Ole Sprengeler, Antje Hebestreit, Stefaan De Henauw, Gabriele Eiben, Regina Felsö, Fabio Lauria, Michael Tornaritis, Toomas Veidebaum, Valeria Pala, Luis A Moreno
OBJECTIVE: Physical activity (PA) levels and dietary habits are considered some of the most important factors associated with obesity. The present study aimed to examine the association between PA level and food and beverage consumption in European children (2-10 years old). Design/Setting/Subjects A sample of 7229 children (49·0 % girls) from eight European countries participating in the IDEFICS (Identification and prevention of Dietary and lifestyle induced health EFfects In Children and infantS) study was included...
February 19, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29457512/perceived-diet-and-exercise-behaviors-among-social-network-members-with-personal-lifestyle-habits-of-public-housing-residents
#4
Kimberly A Gudzune, Jennifer Peyton, Craig Evan Pollack, J Hunter Young, David M Levine, Carl A Latkin, Jeanne M Clark
Our objective was to characterize the relationship between public housing residents' diet/exercise habits with similar behaviors among their social network. We conducted a cross-sectional survey of randomly selected households in Baltimore, Maryland, from August 2014 to August 2015. Adult heads of household completed questions on diet, exercise, and perceived habits among network members. Our dependent variables were high added sugar intake (≥39.9 teaspoons/day), high fruit/vegetable intake (≥6.1 servings/day), and being physically active (≥moderately activity)...
February 1, 2018: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/29457239/patient-care-to-public-health-to-synthetic-biology
#5
EDITORIAL
(no author information available yet)
The January-February 2018 issue of the Hastings Center Report includes pieces addressing patient care concerns that lie at the original core of bioethics and pieces that reflect the field's growing breadth. Among the pieces getting at the original core is an article by philosopher Daniel Brudney on the moral values underpinning surrogate decision-making. The article and the two commentaries that follow it contribute to the debate on the moral authority of surrogate decision-makers. Several items in the issue take up matters of public health and health policy...
January 2018: Hastings Center Report
https://www.readbyqxmd.com/read/29457232/tackling-obesity-and-disease-the-culprit-is-sugar-the-response-is-legal-regulation
#6
Lawrence O Gostin
It is staggering to observe the new normal in America: 37.9 percent of adults are obese, and 70.7 percent are either obese or overweight. One out of every five minors is obese. The real tragedy, of course, is the disability, suffering, and early death that devastates families and communities. But all of society pays, with the annual medical cost estimated at $147 billion. The causal pathways are complex, but if we drill down, sugar is a deeply consequential pathway to obesity, and the single greatest dietary source is sugar-sweetened beverages (SSBs)...
January 2018: Hastings Center Report
https://www.readbyqxmd.com/read/29455757/federal-nutrition-program-revisions-impact-low-income-households-food-purchases
#7
Shu Wen Ng, Bridget A Hollingsworth, Emily A Busey, Julie L Wandell, Donna R Miles, Jennifer M Poti
INTRODUCTION: The Special Supplemental Nutrition Program for Women, Infants and Children (WIC) required major revisions to food packages in 2009; effects on nationwide low-income household purchases remain unexamined. METHODS: This study examines associations between WIC revisions and nutritional profiles of packaged food purchases from 2008 to 2014 among 4,537 low-income households with preschoolers in the U.S. (WIC participating versus nonparticipating) utilizing Nielsen Homescan Consumer Panel data...
March 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29454813/development-and-psychometric-evaluation-of-a-new-measure-to-assess-pregaming-motives-in-spanish-speaking-young-adults
#8
Angelina Pilatti, Jennifer P Read
AIMS: The present study was divided into two different stages that sought to develop (Stage 1) and validate (Stage 2) the Argentinean-version of the Pregaming Motives Questionnaire (PMQ-Arg), a new, ecologically valid measure to assess pregaming (i.e., the consumption of alcohol prior to attending a social/sporting event where alcohol may or may not be available) motives among Spanish-speaking youth. METHOD: Two separate samples of Argentinian young adults (all last-year pregamers) were recruited by disseminating an invitation through online social networks and e-mail listings...
January 31, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29453120/mycobiota-and-co-occurrence-of-mycotoxins-in-south-african-maize-based-opaque-beer
#9
Ifeoluwa Adekoya, Adewale Obadina, Cynthia Chilaka Adaku, Marthe De Boevre, Sheila Okoth, Sarah De Saeger, Patrick Njobeh
Beer, a beverage consumed throughout the world, is mainly derived from cereals. In this study, fungal and mycotoxin contamination, as well as the physicochemical properties of maize-based opaque beer (umqombothi) obtained from the Gauteng province of South Africa, was investigated. The mean water activity, pH and total titratable acidity of the analysed beer samples were 0.91, 3.76 and 1.20% lactic acid, respectively. The investigation revealed Aspergillus, Penicillium, Phoma and Saccharomyces as the predominant fungal genera with a mean fungal load of 3...
February 9, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29452189/roasted-and-green-coffee-extracts-show-antioxidant-and-cytotoxic-activity-in-myoblast-and-endothelial-cell-lines-in-a-cell-specific-manner
#10
Alexandros Priftis, Eleftheria-Maria Panagiotou, Konstantinos Lakis, Christina Plika, Maria Halabalaki, Georgia Ntasi, Aristidis S Veskoukis, Dimitrios Stagos, Leandros A Skaltsounis, Dimitrios Kouretas
Coffee is one of the most highly consumed beverages with potential beneficial health implications, however its molecular mechanism of action has not been completely elucidated yet. To that cause, the polyphenolic composition of different coffee extracts (from Light, Medium and Dark roasts as well as green beans) was examined by UHPLC-HRMS analysis, indicating chlorogenic acids isomers as the main constituents. In the following step, the toxicity of the extracts was tested in myoblasts and endothelial cells and differential toxicity of green and roasted samples was displayed as the myoblasts were more sensitive to green coffee extracts, in contrast to the endothelial cells...
February 13, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29451991/exogenous-ketone-salts-do-not-improve-cognitive-responses-after-a-high-intensity-exercise-protocol-in-healthy-college-aged-males
#11
Hunter S Waldman, Steven A Basham, Ffi G Price, JohnEric W Smith, Harish Chander, Adam C Knight, Ben M Krings, Matthew J McAllister
This study examined the effects of a D-ß-hydroxybutyrate (ßHB) containing beverage on cognitive and performance measures during a bout of repeated Wingates. Fifteen healthy, college-aged males (mean ± SD age: 23.1 ± 2.4 years, height: 165.4 ± 2.0 cm, mass: 81.4 ± 9.2 kg) volunteered for the present study. Trial 1 consisted of baseline measures and familiarization for the protocol. During trials 2 and 3, subjects reported to the laboratory, after a 10 h fast, and ingested 11.38 grams of ßHB or a placebo (PLA) beverage 30 min before exercise...
February 16, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29451639/-analysis-of-foods-advertised-to-childhood-audience-on-chilean-television
#12
Catalina González-Hidalgo
OBJECTIVE: To examine food advertising aimed at childhood's audience broadcast on Chilean television. MATERIALS AND METHODS: Cross-sectional study. Food advertising broadcast by 4 open signal TV channels was recorded for 12 hours daily on twelve days randomly selected. Notices were classified according to food groups and level of processing. The frequency of food advertisement aimed to childhood audience was compared with those for adults. Nutrient profile of foods advertised was described...
November 2017: Salud Pública de México
https://www.readbyqxmd.com/read/29451630/-pattern-changes-in-food-and-beverages-expenditure-in-mexican-households-1984-2014
#13
Beatriz Gabriela Garza-Montoya, María Elena Ramos-Tovar
OBJECTIVE: To analyze the proportion of expenditure and its frequency in food and beverages consumed inside and outside of households, at national and regional level, in Mexico between 1984 and 2014. MATERIALS AND METHODS: It analyzes data of household expenditure of food and beverages taken from the National Survey of Mexican Household Income and Expenditures 1984, 1994, 2005 and 2014. It conducted descriptive statistics analyses such as percentages, growth rates and crosstabs...
November 2017: Salud Pública de México
https://www.readbyqxmd.com/read/29450895/a-test-of-multi-session-automatic-action-tendency-retraining-to-reduce-alcohol-consumption-among-young-adults-in-the-context-of-a-human-laboratory-paradigm
#14
Robert F Leeman, Christine Nogueira, Reinout W Wiers, Janna Cousijn, Kelly Serafini, Kelly S DeMartini, John A Bargh, Stephanie S O'Malley
BACKGROUND: Young adult heavy drinking is an important public health concern. Current interventions have efficacy but with only modest effects, thus novel interventions are needed. In prior studies, heavy drinkers, including young adults, have demonstrated stronger automatically triggered approach tendencies to alcohol-related stimuli than lighter drinkers. Automatic action tendency retraining has been developed to correct this tendency and consequently reduce alcohol consumption. The current study is the first to test multiple iterations of automatic action tendency retraining, followed by laboratory alcohol self-administration...
February 16, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29450747/efficacy-of-bifidobacterium-breve-fermented-milk-in-maintaining-remission-of-ulcerative-colitis
#15
Katsuyoshi Matsuoka, Yukari Uemura, Takanori Kanai, Reiko Kunisaki, Yasuo Suzuki, Kaoru Yokoyama, Naoki Yoshimura, Toshifumi Hibi
BACKGROUND: Fermented milk products containing Bifidobacterium breve strain Yakult (BFM) may improve clinical status in ulcerative colitis (UC) patients. AIMS: To assess efficacy of BFM in maintaining remission in Japanese patients with quiescent UC. METHODS: This double-blind study (B-FLORA) enrolled 195 patients with quiescent UC, randomized to receive one pack of BFM fermented milk per day [Bifidobacterium breve strain Yakult (10 billion bacteria) and Lactobacillus acidophilus (1 billion bacteria)] (n = 98) or matching placebo (n = 97) for 48 weeks...
February 15, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29450221/drinking-game-participation-gender-performance-and-normalization-of-intoxication-among-nigerian-university-students
#16
Emeka Dumbili, Clare Williams
Background: Most research on drinking games (DGs) and the associated risks focuses on Western countries. In the Nigerian context, DGs activity has not attracted scholarly attention but growing media reports indicate that Nigerian youths play DGs, and that a number of gamers have died during or immediately after game-playing. Methods: Drawing on gender performance scripts, we explored the performance of gender through DGs practices and the factors that motivate DGs participation...
June 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29449081/urinary-concentrations-of-benzophenone-type-ultra-violet-light-filters-and-reproductive-parameters-in-young-men
#17
Evdochia Adoamnei, Jaime Mendiola, Miriam Moñino-García, Fernando Vela-Soria, Luz M Iribarne-Durán, Mariana F Fernández, Nicolás Olea, Niels Jørgensen, Shanna H Swan, Alberto M Torres-Cantero
BACKGROUND: Benzophenone (BP)-type ultraviolet (UV) light filters are chemicals frequently added to personal care products, insect repellents, sunscreens, and beverage and food packaging to diminish the harmful effects of UV sunlight on human skin or foodstuffs. BP-type UV filters have shown negative effects on male reproduction function in in vitro and animal models, but human epidemiologic studies are limited. The goal of this study was to examine associations between urinary concentrations of BP-type UV filters and semen quality and reproductive hormone levels...
February 9, 2018: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/29449024/surrogate-alcohol-or-nonbeverage-alcohol-consumption-the-surrogate-alcohol-questionnaire-saq
#18
Ariela Green, Daniel Neff, Greg Giuliano, Nathan Lee, Rachel Turchin, Elisabeth J S Kunkel
BACKGROUND: Diagnosis and treatment of alcohol use disorders and their sequelae are common clinical questions for the consultation-liaison psychiatrist. At an urban, academic medical center, the authors consulted on several patients whose consumption of alcohol included nonbeverage forms of alcohol, (described in the literature as surrogate alcohols, nonbeverage alcohols, e.g., mouthwash). METHODS: The authors describe 4 patients who presented with surrogate alcohol consumption...
January 4, 2018: Psychosomatics
https://www.readbyqxmd.com/read/29447669/highly-sensitive-glucose-sensor-based-on-monodisperse-palladium-nickel-activated-carbon-nanocomposites
#19
Yağmur Koskun, Aysun Şavk, Betül Şen, Fatih Şen
Glucose enzyme biosensors have been used for a variety of applications such as medical diagnosis, bioprocess engineering, beverage industry and environmental scanning etc. and there is still a growing interest in glucose sensors. For this purpose, addressed herein, as a novel glucose sensor, highly sensitive activated carbon (AC) decorated monodisperse nickel and palladium alloy nanocomposites modified glassy carbon electrode (Ni-Pd@AC/GCE NCs) have been synthesized by in-situ reduction technique. Raman Spectroscopy (RS), X-ray Photoelectron Spectroscopy (XPS), X-ray Diffraction (XRD), Transmission Electron Microscopy (TEM), cyclic voltammetry (CV) and chronoamperometry (CA) were used for the characterization of the prepared non-enzymatic glucose sensor...
June 20, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29446654/hypouricaemic-effects-of-yogurt-containing-lactobacillus-gasseri-pa-3-in-patients-with-hyperuricaemia-and-or-gout-a-randomized-double-blind-placebo-controlled-study
#20
Hisashi Yamanaka, Atsuo Taniguchi, Hiroshi Tsuboi, Hiroshi Kano, Yukio Asami
PURPOSE: Lactobacillus gasseri PA-3 (PA-3) has been previously shown to decrease serum uric acid (SUA) levels in subjects with increased SUA. In this study, we investigated whether PA-3 is also capable of decreasing SUA levels in patients with hyperuricaemia and/or gout. METHODS: Twenty-five patients with hyperuricaemia and/or gout completed this study. Urate-lowering drugs were discontinued for 12 weeks (week -4 to week 8). After flushing of urate-lowering drugs for 4 weeks (week 0), patients were randomized equally to receive diets containing yogurt beverages with PA-3 or without PA-3 for a duration of 8 weeks (week 8)...
February 15, 2018: Modern Rheumatology
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