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https://www.readbyqxmd.com/read/28240008/role-of-plasticity-region-genes-and-cage-gene-of-cagpai-of-helicobacter-pylori-in-development-of-gastrointestinal-gi-diseases
#1
Shokufe GholizadeTobnagh, Seyedeh Zahra Bakhti, Saeid Latifi Navid, Saber Zahri, Fatemeh Sadat Bakhti
Background: Helicobacter pylori is a Gram-negative, micro aerophilic bacterium in the human stomach that is associated with the development of gastrointestinal ailments such as peptic ulcer (PU) and gastric cancer (GC). In the present study, plasticity region genes (jhp0940, jhp0945 and jhp0947) and and cagE gene of cagPAI were assessed independently and in combination for their ability to predict clinical consequences. Materials and Methods: A total of 211 strains which were isolated from patients with different gastrointestinal diseases (114 with non-atrophic gastritis, 59 with PU, and 38 with GC) were genotyped by PCR and sequencing...
1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28239984/cost-effectiveness-of-extended-release-naltrexone-to-prevent-relapse-among-criminal-justice-involved-persons-with-a-history-of-opioid-use-disorder
#2
Sean M Murphy, Daniel Polsky, Joshua D Lee, Peter D Friedmann, Timothy W Kinlock, Edward V Nunes, Richard J Bonnie, Michael Gordon, Donna T Chen, Tamara Y Boney, Charles P O'Brien
BACKGROUND/AIMS: Criminal-justice-involved persons are highly susceptible to opioid relapse and overdose-related deaths. In a recent randomized trial, we demonstrated the effectiveness of extended release naltrexone (XR-NTX; Vivitrol®) in preventing opioid relapse among criminal-justice-involved U.S. adults with a history of opioid use disorder. The cost of XR-NTX may be a significant barrier to adoption. Thus, it is important to account for improved quality of life, and downstream cost-offsets...
February 26, 2017: Addiction
https://www.readbyqxmd.com/read/28239958/differential-sex-effects-of-systolic-blood-pressure-and-ldl-c-on-type-2-diabetes-life-course-data-from-the-bogalusa-heart-study
#3
Benjamin D Pollock, Wei Chen, Emily W Harville, Tian Shu, Vivian Fonseca, Franck Mauvais-Jarvis, Tanika N Kelly, Lydia A Bazzano
BACKGROUND: There may be sex-specific cardiometabolic mechanisms early in life that affect the development of type 2 diabetes (T2DM) through mid-adulthood. Yet, there have been few studies examining whether early life-course interactions between cardiometabolic risk factors and sex are associated with incident T2DM. METHODS: We followed n = 7,725 children from the Bogalusa Heart Study through mid-adulthood to examine whether low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), body mass index (BMI), or systolic blood pressure (SBP) differentially impact the risk of T2DM for females versus males...
February 27, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28239952/increased-hippocampal-thalamus-and-amygdala-volume-in-long-term-lithium-treated-bipolar-i-disorder-patients-compared-with-unmedicated-patients-and-healthy-subjects
#4
Carlos López-Jaramillo, Cristian Vargas, Ana M Díaz-Zuluaga, Juan David Palacio, Gabriel Castrillón, Carrie Bearden, Eduard Vieta
OBJECTIVE: Magnetic resonance imaging (MRI) studies in bipolar I disorder (BD-I) suggest that lithium is associated with increased volumes of cortico-limbic structures. However, more rigorous control of confounding factors is needed to obtain further support for this hypothesis. The aim of the present study was to assess differences in brain volumes among long-term lithium-treated BD-I patients, unmedicated BD-I patients, and healthy controls. METHODS: This was a cross-sectional study with 32 euthymic BD-I patients (16 on lithium monotherapy for a mean of 180 months, and 16 receiving no medication for at least the 2 months prior to the study) and 20 healthy controls...
February 27, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28239917/decrease-in-mortality-of-adult-epilepsy-patients-since-1980-lessons-learned-from-a-hospital-based-cohort
#5
C A Granbichler, W Oberaigner, G Kuchukhidze, J-P Ndayisaba, A Ndayisaba, A Taylor, G Bauer, G Luef, E Trinka
BACKGROUND AND PURPOSE: Data on mortality in patients with epilepsy have been available since the 1800s. They consistently show a 2-3-fold increase compared to the general population. Despite major advances in diagnostic tools and treatment options, there is no evidence for a decrease in premature deaths. The temporal trend of mortality in a hospital-based epilepsy cohort over three decades was assessed. METHODS: A hospital-based incidence cohort was recruited from a specialized epilepsy outpatient clinic at Innsbruck Medical University between 1980 and 2007, divided by decade into three cohorts and followed for 5 years after initial epilepsy diagnosis...
February 27, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28239910/adverse-symptoms-of-immunosuppressants-a-survey-of-canadian-transplant-clinicians
#6
J J Harrison, H Mansell, T Blydt-Hansen
Adverse symptoms of immunosuppressants (ASI) impact quality of life (QOL) in solid organ transplant recipients, however standardized approaches for active ASI surveillance and intervention are lacking. While management is highly clinician-dependent, clinician views remain largely unexplored. We surveyed Canadian Society of Transplantation members on their perceptions of ASI including frequency, perceived QOL impact, causal attribution, management strategies and success. Sixty-one clinicians participated in the survey of 12 ASI (tremor, diarrhea, nausea, constipation, dyspnea, insomnia, edema, dyspnea, arthralgia, acne, mouth sores, paresthesias), for a 22% response rate...
February 26, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28239857/neospora-caninum-in-beef-herds-in-new-south-wales-australia-1-seroprevalence-study
#7
B J Moloney, P D Kirkland, C Heuer
OBJECTIVE: To determine the seroprevalence of Neospora caninum antibodies in beef breeding herds across New South Wales (NSW) and to determine if there are any differences associated with geographic location and other herd-level factors. METHODS: Cross-sectional survey of beef breeding cows (n = 3298) from 63 properties (approximately 55 cows per herd) sampled randomly from six regions in NSW using a multistage survey design. Samples were tested by ELISA for N...
March 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28239800/intermediate-cd14-cd16-monocyte-predicts-severe-coronary-stenosis-and-extensive-plaque-involvement-in-asymptomatic-individuals
#8
Shyh-Chyi Lo, Wen-Jeng Lee, Ching-Yi Chen, Bai-Chin Lee
Circulating leukocyte subtypes and monocyte subsets are independent predictors of cardiovascular events. We hypothesized that an increased leukocyte subtype would predict severe coronary stenosis and extensive plaque involvement. We retrospectively analyzed clinical, laboratory, and coronary CT data in a total of 588 asymptomatic adults (69% men; mean age, 57 ± 9 years) undergoing a general health check-up. Intermediate CD14(++)CD16(+) monocyte count had the strongest association with mixed and calcified plaque scores, whereas the numbers of neutrophils and classical CD14(++)CD16(-) monocytes were significantly associated with non-calcified plaque score...
February 26, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28239722/transient-inhomogeneous-flow-patterns-in-supercooled-liquids-under-shear
#9
Ingo Fuereder, Patrick Ilg
Supercooled liquids and other soft glassy systems show characteristic spatial inhomogeneities in their local dynamical properties. Using detailed molecular dynamics simulations, we find that for sufficiently low temperatures and sufficiently high shear rates supercooled liquids also show transient inhomogeneous flow patterns (shear banding) in the start-up of steady shear flow, similar to what has already been observed for many other soft glassy systems. We verify that the onset of transient shear banding coincides quite well with the appearance of a stress overshoot for temperatures in the supercooled regime...
February 27, 2017: Soft Matter
https://www.readbyqxmd.com/read/28239601/public-versus-private-drug-insurance-and-outcomes-of-patients-requiring-biologic-therapies-for-inflammatory-bowel-disease
#10
Amir Rumman, Roberto Candia, Justina J Sam, Kenneth Croitoru, Mark S Silverberg, A Hillary Steinhart, Geoffrey C Nguyen
Background. Antitumor necrosis factor (anti-TNF) therapy is a highly effective but costly treatment for inflammatory bowel disease (IBD). Methods. We conducted a retrospective cohort study of IBD patients who were prescribed anti-TNF therapy (2007-2014) in Ontario. We assessed if the insurance type was a predictor of timely access to anti-TNF therapy and nonroutine health utilization (emergency department visits and hospitalizations). Results. There were 268 patients with IBD who were prescribed anti-TNF therapy...
2017: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28239598/general-self-efficacy-and-diabetes-management-self-efficacy-of-diabetic-patients-referred-to-diabetes-clinic-of-aq-qala-north-of-iran
#11
Hajar Dehghan, Abdurrahman Charkazi, Ghorban Mohammad Kouchaki, Bagher Pahlevan Zadeh, Bibi Azizieh Dehghan, Mohammad Matlabi, Morteza Mansourian, Mostafa Qorbani, Omid Safari, Tahereh Pashaei, Babak Rastegari Mehr
BACKGROUND: Self-efficacy is one of the factors involved in successful self-care of diabetic patients. The aim of this study was to evaluate general self-efficacy and diabetes management self-efficacy and to determine their association with glycemic control in diabetic individuals, referred to the diabetes clinic of Aq Qala city, North of Iran. METHODS: In this cross-sectional study, 251 type 2 diabetes mellitus patients were enrolled using census method. Data collection tools consisted of Sherer General Self-Efficacy Scale (SGSES) and Diabetes Management Self-Efficacy Scale (DMSES) with minor demographic adjustments and hemoglobin A1C test...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/28239560/risk-factors-for-hearing-impairment-among-adults-with-diabetes-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#12
Kathleen E Bainbridge, Catherine C Cowie, Franklyn Gonzalez, Howard J Hoffman, Elizabeth Dinces, Jeremiah Stamler, Karen J Cruickshanks
AIM: The aim was to examine risk factors for hearing impairment among Hispanic/Latino adults with diabetes. METHODS: Findings are based on 3384 participants aged 18-76 years with diagnosed or previously undetected diabetes who completed audiometric testing as part of the Hispanic Community Health Study/Study of Latinos. We defined hearing impairment as the pure-tone average (PTA) >25 decibels hearing level [dB HL] of pure-tone thresholds at high frequencies (3000, 4000, 6000, and 8000 Hz) in the worse ear and defined a second hearing impairment outcome with the additional requirement of PTA >25 dB HL of low/mid-frequency (500, 1000, and 2000 Hz) thresholds in the worse ear...
December 2016: Journal of Clinical & Translational Endocrinology
https://www.readbyqxmd.com/read/28239452/intervening-with-healthcare-workers-hand-hygiene-compliance-knowledge-and-perception-in-a-limited-resource-hospital-in-indonesia-a-randomized-controlled-trial-study
#13
Dewi Santosaningsih, Dewi Erikawati, Sanarto Santoso, Noorhamdani Noorhamdani, Irene Ratridewi, Didi Candradikusuma, Iin N Chozin, Thomas E C J Huwae, Gwen van der Donk, Eva van Boven, Anne F Voor In 't Holt, Henri A Verbrugh, Juliëtte A Severin
BACKGROUND: Hand hygiene is recognized as an important measure to prevent healthcare-associated infections. Hand hygiene adherence among healthcare workers is associated with their knowledge and perception. This study aimed to evaluate the effect of three different educational programs on improving hand hygiene compliance, knowledge, and perception among healthcare workers in a tertiary care hospital in Indonesia. METHODS: The study was performed from May to October 2014 and divided into a pre-intervention, intervention, and post-intervention phase...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28239393/thermo-sensitive-polymer-nanospheres-as-a-smart-plugging-agent-for-shale-gas-drilling-operations
#14
Wei-Ji Wang, Zheng-Song Qiu, Han-Yi Zhong, Wei-An Huang, Wen-Hao Dai
Emulsifier-free poly(methyl methacrylate-styrene) [P(MMA-St)] nanospheres with an average particle size of 100 nm were synthesized in an isopropyl alcohol-water medium by a solvothermal method. Then, through radical graft copolymerization of thermo-sensitive monomer N-isopropylacrylamide (NIPAm) and hydrophilic monomer acrylic acid (AA) onto the surface of P(MMA-St) nanospheres at 80 °C, a series of thermo-sensitive polymer nanospheres, named SD-SEAL with different lower critical solution temperatures (LCST), were prepared by adjusting the mole ratio of NIPAm to AA...
2017: Pet Sci
https://www.readbyqxmd.com/read/28239223/exercise-reduces-depressive-symptoms-in-adults-with-arthritis-evidential-value
#15
George A Kelley, Kristi S Kelley
PURPOSE: Determine whether evidential value exists that exercise reduces depressive symptoms in adults with arthritis and other rheumatic diseases. METHODS: Using data from a previous meta-analysis of 29 published studies that included 2449 participants (1470 exercise, 979 control) with fibromyalgia, osteoarthritis, rheumatoid arthritis or systemic lupus erythematosus, a novel, recently developed method, p-curve, was used to assess for evidential value and rule out selective reporting of statistically significant findings regarding exercise and depressive symptoms in adults with arthritis and other rheumatic diseases...
May 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28239217/sibling-relationship-quality-and-mexican-origin-adolescents-and-young-adults-familism-values-and-adjustment
#16
Sarah E Killoren, Sue A Rodríguez De Jesús, Kimberly A Updegraff, Lorey A Wheeler
We examined profiles of sibling relationship qualities in 246 Mexican-origin families living in the United States using latent profile analyses. Three profiles were identified: Positive, Negative and Affect-Intense. Links between profiles and youths' familism values and adjustment were assessed using longitudinal data. Siblings in the Positive profile reported the highest familism values, followed by siblings in the Affect-Intense profile and, finally, siblings in the Negative profile. Older siblings in the Positive and Affect-Intense profiles reported fewer depressive symptoms than siblings in the Negative profile...
March 2017: International Journal of Behavioral Development
https://www.readbyqxmd.com/read/28239015/financial-strain-is-associated-with-medication-nonadherence-and-worse-self-rated-health-among-cardiovascular-patients
#17
Chandra Y Osborn, Sunil Kripalani, Kathryn M Goggins, Kenneth A Wallston
Non-traditional indicators of socioeconomic status (SES; e.g., home ownership) may be just as or even more predictive of health outcomes as traditional indicators of SES (e.g., income). This study tested whether financial strain (i.e., difficulty paying monthly bills) predicted medication non-adherence and worse self-rated health. Research assistants administered surveys to 1,527 patients with acute coronary syndromes or acute decom-pensated heart failure. In adjusted models, having a higher income was associated with being more adherent (p < ...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28239011/the-changing-face-of-treatment-mental-health-concerns-and-integrated-care-in-an-hiv-clinic
#18
Eliot J Lopez, Thomas Toomey, Kimberly Lewis, Shirin Khazvand, Rebecca M Floyd, Kena R Arnold, Lara M Stepleman
Though advances in medical treatment have increased lifespans for those living with HIV, quality of life concerns often remain under-treated by health care providers. The integration of mental health services within the HIV medical setting can provide comprehensive care for patients, including brief screening, intervention, and appropriate follow-up. In this study, investigators examined mental health concerns identified during behavioral health screens at appointments in an Infectious Disease Clinic and compared them with previously published data from the same setting to assess changes in patient-reported problems...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28239006/cancer-treatment-delays-in-american-indians-and-alaska-natives-enrolled-in-medicare
#19
Scott V Adams, Aasthaa Bansal, Andrea N Burnett-Hartman, Stacey A Cohen, Andrew Karnopp, Victoria Warren-Mears, Scott D Ramsey
To assess whether timing of initial post-diagnosis cancer care differs between American Indian and Alaska Native (AI/AN) and non-Hispanic White (NHW) patients, we accessed SEER-Medicare data for breast, colorectal, lung, and prostate cancers (2001-2007). Medicare claims data were examined for initiation of cancer-directed treatment. Overall, AI/ANs experienced longer median times to starting treatment than NHWs (45 and 39 days, p < .001) and lower rates of treatment initiation (HR[95%CI]: 0.86[0.79-0.93])...
2017: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/28239004/cancer-mortality-in-the-mississippi-delta-region-descriptive-epidemiology-and-needed-future-research-and-interventions
#20
Whitney E Zahnd, Wiley D Jenkins, Georgia S Mueller-Luckey
The Delta Region is a federally designated, socioeconomically disadvantaged region of the United States covering 252 counties in eight states along the Mississippi River. The objective of this study is to describe the Region's cancer mortality burden. National Center for Health Statistics data were used to calculate age-adjusted mortality rates and rate ratios for the Delta Region for all cancers, lung, colorectal, breast (female), cervical, and prostate cancers. Rates were also calculated for comparison groups, and were stratified by gender, race, rurality, and socioeconomic status...
2017: Journal of Health Care for the Poor and Underserved
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