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https://www.readbyqxmd.com/read/28346975/hypothyroidism-is-associated-with-all-cause-mortality-in-a-national-cohort-of-chronic-hemodialysis-patients
#1
Hsuan-Jen Lin, Chung-Chih Lin, Hsuan Ming Lin, Hsuan-Ju Chen, Che-Chen Lin, Chiz-Tzung Chang, Che-Yi Chou, Chiu-Ching Huang
BACKGROUND: The prevalence of hypothyroidism is high in hemodialysis (HD) patients and hypothyroidism increases all-cause mortality in HD patients. Comorbidities are common in HD patients and are associated with both mortality and hypothyroidism. The aim of the study is to explore the effect of the interactions of comorbidities and hypothyroidism on all-cause mortality in HD patients. METHOD: Patients with hypothyroidism (ICD-9-CM 244.0, 244.1, and 244.9) and matched patients without hypothyroidism in the Registry for Catastrophic Illness Patient Database of Taiwan Health Insurance from 2000 to 2010 were analyzed...
March 27, 2017: Nephrology
https://www.readbyqxmd.com/read/28346954/evaluation-of-probably-benign-adnexal-masses-in-postmenopausal-women
#2
Burcu Kisa Karakaya, Emre Ozgu, Hatice Celik Kansu, Ozlem Evliyaoglu, Esma Sarikaya, Bugra Coskun, Salim Erkaya
Background Preoperatively identification of malignancy potential of a postmenopausal adnexal masses is important. Aim To evaluate the effectiveness of the Risk of Malignancy Index-2 in presumably benign adnexal masses in postmenopausal women. Study Design Retrospective, observational study. Methods 119 women with postmenopausal adnexal masses with a preliminary diagnosis of benign tumors according to the Risk of Malignancy Index-2 were included. Age, duration of menopause, ultrasonographic findings, and serum CA-125 levels were recorded preoperatively...
March 27, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28346913/selected-food-consumption-mediates-the-association-between-education-level-and-metabolic-syndrome-in-korean-adults
#3
Oh Yoen Kim, So-Young Kwak, Boeun Kim, Young-Sun Kim, Hye Young Kim, Min-Jeong Shin
BACKGROUND/AIMS: Low socioeconomic status (SES) is linked to higher incidence/mortality of cardiovascular disease, but emerging evidence inconsistently reported that education level, a proxy for SES, is related to cardiovascular risk and metabolic syndrome (MetS) in Koreans. Furthermore, limited information is available on whether dietary components would mediate the relationship between education level and cardiovascular risk. We hypothesized that selected food consumption mediates the association between education level and MetS prevalence...
March 28, 2017: Annals of Nutrition & Metabolism
https://www.readbyqxmd.com/read/28346907/long-term-associations-of-modeled-and-self-reported-measures-of-exposure-to-air-pollution-and-noise-at-residence-on-prevalent-hypertension-and-blood-pressure
#4
Anitha Pitchika, Regina Hampel, Kathrin Wolf, Ute Kraus, Josef Cyrys, Wolfgang Babisch, Annette Peters, Alexandra Schneider
Air pollution, traffic noise and noise annoyance are suggested to be associated with hypertension and blood pressure (BP); however, the evidence remains inconsistent. Our study examined the long-term associations of modeled and self-reported measures of air pollution and traffic noise on prevalent hypertension and BP. We analyzed cross-sectional data from 2552 participants aged 31-72years from the KORA F4 (2006-2008) study conducted in the region of Augsburg, Germany. Land-use regression models were used to estimate residential long-term exposure to particulate matter <2...
March 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28346825/fabrication-of-nico2-anchored-graphene-nanosheets-by-liquid-phase-exfoliation-for-excellent-microwave-absorber
#5
Ruilong Yang, Bochong Wang, Jianyong Xiang, Congpu Mu, Can Zhang, Fusheng Wen, Cong Wang, Can Su, Zhongyuan Liu
Graphene nanosheets (GNS) were prepared by an efficient liquid phase exfoliation method, and then the NiCo2/GNS nanohybrids were fabricated using the single-mode microwave-assisted hydrothermal technique. The NiCo2/GNS composites with different GNS proportion were investigated as a microwave absorber. Morphology investigation suggested that NiCo2 nanocrystals were uniformly anchored on the GNS without aggregation. The electromagnetic parameters of NiCo2/GNS nanohybrids could be artificially adjusted by changing the GNS proportion, which led to an exceptional microwave absorbing performance...
March 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28346659/is-universal-hla-b-15-02-screening-a-cost-effective-option-in-an-ethnically-diverse-population-a-case-study-of-malaysia
#6
H Y Chong, Z Mohamed, L L Tan, D B C Wu, F H Shabaruddin, M Dahlui, Y D Apalasamy, S R Snyder, M S Williams, J Hao, L H Cavallari, N Chaiyakunapruk
BACKGROUND: Strong association was documented between human leukocyte antigen (HLA)-B*15:02 and carbamazepine-induced severe cutaneous adverse reactions (SCARs) in Asians. Beyond Asia, the HLA testing is potentially valuable in many countries with increasingly diverse communities of Asian ancestry, to facilitate an early recognition of patient susceptibility to SCARs. OBJECTIVE: To determine the cost-effectiveness of universal HLA-B*15:02 screening in preventing carbamazepine-induced Stevens-Johnson syndrome/ toxic epidermal necrolysis in an ethnically-diverse Malaysian population...
March 27, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28346655/high-prevalence-of-alcohol-use-disorders-in-patients-with-inflammatory-skin-diseases
#7
K Al-Jefri, D Newbury-Birch, C R Muirhead, E Gilvarry, V Araújo-Soares, N J Reynolds, E Kaner, P J Hampton
BACKGROUND: There is a known association between psoriasis and heavy alcohol consumption. Causality remains unclear with evidence supporting both alcohol triggering psoriasis and psoriasis predisposing to heavy alcohol consumption. However, the association between heavy alcohol consumption and other inflammatory skin diseases remains to be defined. OBJECTIVE: To examine the prevalence of heavy drinking using the Alcohol Use Disorders Identification Test (AUDIT) in patients with inflammatory skin disease...
March 27, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28346597/association-of-risk-of-viremia-immunosuppression-serious-clinical-events-and-mortality-with-increasing-age-in-perinatally-human-immunodeficiency-virus-infected-youth
#8
Anne M Neilan, Brad Karalius, Kunjal Patel, Russell B Van Dyke, Mark J Abzug, Allison L Agwu, Paige L Williams, Murli Purswani, Deborah Kacanek, James M Oleske, Sandra K Burchett, Andrew Wiznia, Miriam Chernoff, George R Seage, Andrea L Ciaranello
Importance: As perinatally human immunodeficiency virus-infected youth (PHIVY) in the United States grow older and more treatment experienced, clinicians need updated information about the association of age, CD4 cell count, viral load (VL), and antiretroviral (ARV) drug use with risk of opportunistic infections, key clinical events, and mortality to understand patient risks and improve care. Objective: To examine the incidence or first occurrence during follow-up of key clinical events (including Centers for Disease Control and Prevention stage B [CDC-B] and stage C [CDC-C] events) and mortality among PHIVY stratified by age, CD4 cell count, and VL and ARV status...
March 27, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28346595/association-of-gastric-acid-suppression-with-recurrent-clostridium-difficile-infection-a-systematic-review-and-meta-analysis
#9
Raseen Tariq, Siddharth Singh, Arjun Gupta, Darrell S Pardi, Sahil Khanna
Importance: Gastric acid suppression has been associated with an increased risk of primary Clostridium difficile infection (CDI), but the risk of recurrent CDI in patients taking gastric acid suppressant medications is unclear. Objective: To perform a systematic review and meta-analysis to evaluate the association between gastric acid suppressants and recurrent CDI. Data Sources: MEDLINE, EMBASE, the Cochrane Central Register, the Cochrane Database, and Web of Science were searched from January 1, 1995, to September 30, 2015, for studies assessing the association between gastric acid suppressant exposure and recurrent CDI...
March 27, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28346582/rates-and-characteristics-of-paid-malpractice-claims-among-us-physicians-by-specialty-1992-2014
#10
Adam C Schaffer, Anupam B Jena, Seth A Seabury, Harnam Singh, Venkat Chalasani, Allen Kachalia
Importance: Although physician concerns about medical malpractice are substantial, national data are lacking on the rate of claims paid on behalf of US physicians by specialty. Objective: To characterize paid malpractice claims by specialty. Design, Setting, and Participants: A comprehensive analysis was conducted of all paid malpractice claims, with linkage to physician specialty, from the National Practitioner Data Bank from January 1, 1992, to December 31, 2014, a period including an estimated 19...
March 27, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28346566/gene-gene-interaction-between-pparg-and-apoe-gene-on-late-onset-alzheimer-s-disease-a-case-control-study-in-chinese-han-population
#11
S Wang, L Guan, D Luo, J Liu, H Lin, X Li, X Liu
AIMS: The aim was to investigate the impact of PPARG and APOE gene single nucleotide polymorphisms (SNPs) and additional gene- gene interaction on late-onset Alzheimer's disease (LOAD) risk based on Chinese Han population. METHODS: A total of 928 participants (466 males, 462 females), with a mean age of 81.3 ± 16.4 years old, were included in the study, including 460 LOAD patients and 468 normal controls participants. Logistic regression was performed to investigate association between SNP and LOAD risk and generalized multifactor dimensionality reduction (GMDR) was used to analysis the gene-gene interaction...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28346565/anticholinergic-burden-and-functional-status-in-older-people-with-cognitive-impairment-results-from-the-regal-project
#12
V Boccardi, M Baroni, L Paolacci, S Ercolani, A Longo, M Giordano, C Ruggiero, P Mecocci
OBJECTIVE: The use of drugs with intrinsic anticholinergic properties is widespread among old age persons. A growing body of evidences suggest that a high anticholinergic burden is associated with physical and cognitive impairment. However, the association between anticholinergic drug use and functional status is still poorly investigated, particularly among subjects with initial cognitive impairment. DESIGN: Cross-sectional study examining the association between drug-related anticholinergic burden and functional status in cognitively healthy (CH) (n=691), mild cognitive impairment (MCI) (n=541) or mild Alzheimer's diseases (AD) (n=1127) subjects...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28346564/the-relationship-between-body-mass-index-and-10-year-trajectories-of-physical-functioning-in-middle-aged-and-older-russians-prospective-results-of-the-russian-hapiee-study
#13
Y Hu, S Malyutina, H Pikhart, A Peasey, M V Holmes, J Hubacek, D Denisova, Y Nikitin, M Bobak
OBJECTIVE: To investigate the associations of overweight and obesity with longitudinal decline in physical functioning (PF) among middle-aged and older Russians. DESIGN: Prospective cohort study. SETTING: Four rounds of data collection in the Russian Health, Alcohol and Psychosocial factors In Eastern Europe study with up to 10 years of follow-up. PARTICIPANTS: 9,222 men and women aged 45-69 years randomly selected from the population of two districts of Novosibirsk, Russia...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28346562/joint-association-of-obesity-and-hypertension-with-disability-in-the-elderly-a-community-based-study-of-residents-in-shanghai-china
#14
P Su, H Ding, W Zhang, G Duan, Y Yang, J Long, L Du, C Xie, C Jin, C Hu, Z Sun, Z Duan, L Gong, W Tian
BACKGROUND: Although both obesity and hypertension are known risk factors for disability, the joint association of obesity and hypertension with risk of disability is unknown. This paper is aim to examine the joint association of obesity and hypertension with risk of disability. METHODS: Cross-sectional study with 8060 elderly community-dwelling individuals participating in the survey initiated by Shanghai Health and Family Planning Commission from March to September 2013...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28346539/is-there-a-relation-between-novelty-seeking-striatal-dopamine-release-and-frontal-cortical-thickness
#15
Natalia Jaworska, Sylvia M Cox, Kevin F Casey, Isabelle Boileau, Mariya Cherkasova, Kevin Larcher, Alain Dagher, Chawki Benkelfat, Marco Leyton
BACKGROUND: Novelty-seeking (NS) and impulsive personality traits have been proposed to reflect an interplay between fronto-cortical and limbic systems, including the limbic striatum (LS). Although neuroimaging studies have provided some evidence for this, most are comprised of small samples and many report surprisingly large effects given the challenges of trying to relate a snapshot of brain function or structure to an entity as complex as personality. The current work tested a priori hypotheses about associations between striatal dopamine (DA) release, cortical thickness (CT), and NS in a large sample of healthy adults...
2017: PloS One
https://www.readbyqxmd.com/read/28346536/water-sanitation-and-hygiene-wash-and-environmental-risk-factors-for-soil-transmitted-helminth-intensity-of-infection-in-timor-leste-using-real-time-pcr
#16
Suzy J Campbell, Susana V Nery, Rebecca Wardell, Catherine A D'Este, Darren J Gray, James S McCarthy, Rebecca J Traub, Ross M Andrews, Stacey Llewellyn, Andrew J Vallely, Gail M Williams, Archie C A Clements
BACKGROUND: No investigations have been undertaken of risk factors for intensity of soil-transmitted helminth (STH) infection in Timor-Leste. This study provides the first analysis of risk factors for intensity of STH infection, as determined by quantitative PCR (qPCR), examining a broad range of water, sanitation and hygiene (WASH) and environmental factors, among communities in Manufahi District, Timor-Leste. METHODS: A baseline cross-sectional survey of 18 communities was undertaken as part of a cluster randomised controlled trial, with additional identically-collected data from six other communities...
March 27, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28346522/decline-in-lung-function-rather-than-baseline-lung-function-is-associated-with-the-development-of-metabolic-syndrome-a-six-year-longitudinal-study
#17
Soo Kyoung Kim, Ji Cheol Bae, Jong-Ha Baek, Jae Hwan Jee, Kyu Yeon Hur, Moon-Kyu Lee, Jae Hyeon Kim
This study was conducted to investigate whether baseline lung function or change in lung function is associated with the development of metabolic syndrome (MS) in Koreans. We analyzed clinical and laboratory data from 3,768 Koreans aged 40-60 years who underwent medical check-ups over a six-year period between 2006 and 2012. We calculated the percent change in forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1) over the study period. We tested for an association between baseline lung function or lung function change during the follow-up period and the development of MS...
2017: PloS One
https://www.readbyqxmd.com/read/28346513/cystatin-c-estimated-glomerular-filtration-rate-to-assess-renal-function-in-early-stages-of-autosomal-dominant-polycystic-kidney-disease
#18
Laia Sans, Aleksandar Radosevic, Claudia Quintian, Rosario Montañés, Silvia Gràcia, Carles Vilaplana, Sergi Mojal, José A Ballarin, Patricia Fernández-Llama, Roser Torra, Julio Pascual
BACKGROUND/AIMS: Height-adjusted total kidney volume (htTKV) is the best marker of disease progression in early autosomal dominant polycystic kidney disease (ADPKD) when renal function still remains normal. The usefulness of cystatin-C as a biomarker to assess renal function according to renal volume has not been studied in ADPKD patients. METHODS: Observational and cross-sectional study of 62 ADPKD patients. htTKV, creatinine and cystatin-C estimated glomerular filtration rate (eGFR) were determined...
2017: PloS One
https://www.readbyqxmd.com/read/28346416/jacie-accreditation-for-blood-and-marrow-transplantation-past-present-and-future-directions-of-an-international-model-for-healthcare-quality-improvement
#19
J A Snowden, E McGrath, R F Duarte, R Saccardi, K Orchard, N Worel, J Kuball, C Chabannon, M Mohty
Blood and marrow transplantation (BMT) is a complex and evolving medical speciality that makes substantial demands on healthcare resources. To meet a professional responsibility to both patients and public health services, the European Society for Blood and Marrow Transplantation (EBMT) initiated and developed the Joint Accreditation Committee of the International Society for Cellular Therapy and EBMT-better known by the acronym, JACIE. Since its inception, JACIE has performed over 530 voluntary accreditation inspections (62% first time; 38% reaccreditation) in 25 countries, representing 40% of transplant centres in Europe...
March 27, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28346353/intake-and-dietary-food-sources-of-fibre-in-spain-differences-with-regard-to-the-prevalence-of-excess-body-weight-and-abdominal-obesity-in-adults-of-the-anibes-study
#20
Liliana G González-Rodríguez, José Miguel Perea Sánchez, Javier Aranceta-Bartrina, Ángel Gil, Marcela González-Gross, Lluis Serra-Majem, Gregorio Varela-Moreiras, Rosa M Ortega
The aim was to study the intake and food sources of fibre in a representative sample of Spanish adults and to analyse its association with excess body weight and abdominal obesity. A sample of 1655 adults (18-64 years) from the ANIBES ("Anthropometric data, macronutrients and micronutrients intake, practice of physical activity, socioeconomic data and lifestyles") cross-sectional study was analysed. Fibre intake and dietary food sources were determined by using a three-day dietary record. Misreporters were identified using the protocol of the European Food Safety Authority...
March 25, 2017: Nutrients
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