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Preterm infants

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https://www.readbyqxmd.com/read/29783269/adding-paracetamol-to-ibuprofen-for-the-treatment-of-patent-ductus-arteriosus-in-preterm-infants-a-double-blind-randomized-placebo-controlled-pilot-study
#1
Ori Hochwald, Gur Mainzer, Liron Borenstein-Levin, Huda Jubran, Gil Dinur, Meirav Zucker, Malka Mor, Asaad Khoury, Amir Kugelman
OBJECTIVE:  The objective of this study was to compare the closure rate of hemodynamically significant patent ductus arteriosus (hsPDA) of intravenous ibuprofen + paracetamol (acetaminophen) versus ibuprofen + placebo, in preterm infants of 24 to 316/7 weeks postmenstrual age. STUDY DESIGN:  This is a single-center, double-blind, randomized controlled pilot study. Infants were assigned for treatment with either intravenous ibuprofen + paracetamol ( n  = 12) or ibuprofen + placebo ( n  = 12)...
May 21, 2018: American Journal of Perinatology
https://www.readbyqxmd.com/read/29782437/skin-injuries-and-chlorhexidine-gluconate-based-antisepsis-in-early-premature-infants-a-case-report-and-review-of-the-literature
#2
Valentina Vanzi, Rosanna Pitaro
Early premature infants are subjected to many invasive procedures in neonatal intensive care units, and effective skin antisepsis is an essential step in caring for these vulnerable patients. Nevertheless, preterm infants have an anatomically and physiologically immature skin and preserving their skin integrity is essential to avoid the risk of local and systemic complications. Skin particularities of newborns reduce the list of available antiseptics in neonatology. Chlorhexidine gluconate (CHG) has excellent antiseptic properties and its antimicrobial efficacy cannot be understated, but there is great concern about its use for premature infants, referring to the risk of development skin injuries, such as skin erythema, burns, and blisters...
May 17, 2018: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/29782435/biobehavioral-responses-of-preterm-infants-to-conventional-and-swaddled-tub-baths-a-randomized-crossover-trial
#3
Patrícia de Freitas, Mariana Bueno, Diane Holditch-Davis, Hudson Pires Santos, Amélia Fumiko Kimura
Bathing is a routine care procedure that exposes preterm infants to prolonged handling, which could cause stress and potentially disrupt infants' biobehavioral responses. The aim of this double-blind randomized crossover trial was to compare the preterm infant's body temperature, heart rate (HR), peripheral capillary oxygen saturation (SpO2), salivary cortisol levels, and sleep-wake states during and after swaddled and conventional tub baths. Forty-three infants born at 32 to 36 weeks postmenstrual age, weighing 2225 g or less, were enrolled in the study...
May 18, 2018: Journal of Perinatal & Neonatal Nursing
https://www.readbyqxmd.com/read/29781955/involvements-of-parents-in-the-care-of-preterm-infants-a-pilot-study-evaluating-a-family-centered-care-intervention-in-a-chinese-neonatal-icu
#4
Rong Zhang, Rui-Wena Huang, Xi-Ronga Gao, Xiao-Minga Peng, Li-Hui Zhu, Ramanathan Rangasamy, Jos M Latour
OBJECTIVES: To evaluate the effectiveness and safety of a family-centered care intervention in a Chinese neonatal ICU. DESIGN: Pilot study using a randomized controlled trial design to inform a main randomized controlled trial study. SETTING: Stand-alone tertiary children's hospital in China with a 60-bed neonatal ICU serving as a regional neonatal ICU center. PATIENTS: Premature infants (n = 61) and their parents (n = 110)...
May 17, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/29780796/cerebral-blood-volume-during-neonatal-transition-in-term-and-preterm-infants-with-and-without-respiratory-support
#5
Bernhard Schwaberger, Gerhard Pichler, Corinna Binder-Heschl, Nariae Baik-Schneditz, Alexander Avian, Berndt Urlesberger
Background: Recently, we demonstrated that in healthy newborn infants cerebral blood volume (CBV) was decreasing continuously after birth. We hypothesized that this was due to the increase in oxygen delivery to the brain during neonatal transition. Thus delayed cerebral oxygen delivery in infants in need for respiratory support (RS) during postnatal stabilization might influence changes in CBV. Objective: Aim of the study was to evaluate transitional changes in CBV immediately after birth in term and preterm infants with and without need of RS...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29780352/the-nomogram-of-penile-length-and-circumference-in-iranian-term-and-preterm-neonates
#6
Fahimeh Soheilipour, Farzaneh Rohani, Elham Hashemi Dehkordi, Roya Isa Tafreshi, Parisa Mohagheghi, Seyed-Mohammadsalar Zaheriani, Fatemeh Jesmi, Hamid Salehiniya
Background and objectives: The normal length of penis in preterm and term neonates is different among different nations, and is affected by various factors. The present study aimed to determine stretched penile length (SPL) values and cutoff level of micropenis in term and preterm Iranian neonates, for the first time. Materials and methods: All male neonates born in two general hospitals of Tehran (Akbarabadi, and Rasoul hospitals), center of Iran, with gestational age of 28-42 weeks were included and their SPL and penile circumference (PC) were examined on the first 3 days after birth by the same physician...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29779763/bathing-a-premature-infant-in-the-intensive-care-unit-a-systematic-review
#7
REVIEW
Daniel Fernández, Rebeca Antolín-Rodríguez
PROBLEM: Daily bathing of the preterm infant in the Neonatal Intensive Care Unit (NICU) is a process that is usually done routinely, but it can cause many adverse effects on the stability of the infant. Highlights include decreased body temperature and increased stress, which can cause alterations in its proper growth and development. ELIGIBILITY CRITERIA: We included both descriptive studies and analytical studies that evaluated the effects of bathing on the physiological state of the preterm infants admitted to NICU...
May 17, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29779419/an-evaluation-of-hearing-in-infants-administered-with-colistin-in-the-premature-neonatal-intensive-care-unit
#8
Selman Sarıca, Sadık Yurttutan
AIM: The aim of this study was to investigate the effects of colistin on hearing by evaluating the otoacoustic emission tests and clinical auditory brainstem responses in preterm infants treated with colistin in the neonatal intensive care unit. METHOD: The study included 30 neonates (male: n = 16, female: n = 14) born before 37 weeks who were admitted to the Neonatal Intensive Care Unit at the Kahramanmaras Sutcu Imam Medical Faculty between January 2014 and January 2015 and who were treated with colistin during their time in intensive care because of infection...
May 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29777555/impact-of-nicu-oral-feeding-on-neuropsychomotor-outcomes-at-9-months-of-corrected-age-in-chinese-low-birth-weight-preterm-infants-a-retrospective-study
#9
Wenwen Ding, Lijin Zhao, Nan Sheng, Jiali Ma, Ying Zhang
AIMS AND OBJECTIVES: To examine the changes in neuropsychomotor development and investigate the effect of feeding progression in Neonatal Intensive Care Unit (NICU) on neuropsychomotor outcomes in low-birth-weight preterm infants within 9 months of corrected age. BACKGROUND: Low-birth-weight (LBW) preterm infants (<37 weeks of gestation and birth weight < 2500 g) are at a high risk for neuropsychomotor development delay. Therefore, exploring NICU practices related to neuropsychomotor development is important...
May 18, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29776928/enrichment-of-clinically-relevant-organisms-in-spontaneous-preterm-delivered-placenta-and-reagent-contamination-across-all-clinical-groups-in-a-large-uk-pregnancy-cohort
#10
Lydia J Leon, Ronan Doyle, Ernest Diez-Benavente, Taane G Clark, Nigel Klein, Philip Stanier, Gudrun E Moore
In this study differences in the placental microbiota of term and preterm deliveries from a large UK pregnancy cohort were studied using 16S targeted amplicon sequencing. The impact of contamination from DNA extraction, PCR reagents, as well as those from delivery itself were also examined. A total of 400 placental samples from 256 singleton pregnancies were analysed and differences investigated between spontaneous preterm, non-spontaneous preterm, and term delivered placenta. DNA from recently delivered placenta was extracted, and screening for bacterial DNA was carried out using targeted sequencing of the 16S rRNA gene on the Illumina MiSeq platform...
May 18, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29776872/oral-glucose-and-listening-to-lullaby-to-decrease-pain-in-preterm-infants-supported-with-ncpap-a-randomized-controlled-trial
#11
Kadir Şerafettin Tekgündüz, Sevinç Polat, Ayşe Gürol, Serap Ejder Apay
Preterm infants spend the early days of their lives in neonatal intensive care units, where they undergo many minor painful procedures. There are many nonpharmacologic methods that can effectively reduce the pain response of neonates who undergo routine procedures. This study aimed to investigate whether oral glucose and listening to lullabies could bring pain relief during the removal and reinsertion of the tracheal tube and also oronasopharyngeal suctioning in premature infants to whom nasal continuous positive airway pressure was applied...
May 15, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29776801/determinants-of-a-good-perinatal-outcome-in-588-pregnancies-in-women-with-type-1-diabetes
#12
J Lepercq, C Le Ray, C Godefroy, L Pelage, D Dubois-Laforgue, J Timsit
AIM: This study assessed pregnancy outcomes in women with type 1 diabetes (T1D) over the last 15 years and identified modifiable factors associated with good perinatal outcomes. METHODS: Pregnancy outcomes were prospectively assessed in this cohort study of 588 singleton pregnancies (441 women) managed by standardized care from 2000 to 2014. A good perinatal outcome was defined as the uncomplicated delivery of a normally formed, non-macrosomic, full-term infant with no neonatal morbidity...
May 8, 2018: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29776704/cerebellar-peduncle-injury-predicts-motor-impairments-in-preterm-infants-a-quantitative-tractography-study-at-term-equivalent-age
#13
Tatsuji Hasegawa, Kei Yamada, Takenori Tozawa, Tomohiro Chiyonobu, Sachiko Tokuda, Akira Nishimura, Hajime Hosoi, Masafumi Morimoto
PURPOSE: Cerebellar injury is well established as an important finding in preterm infants with cerebral palsy (CP). In this study, we investigated associations between injury to the cerebellar peduncles and motor impairments in preterm infants using quantitative tractography at term-equivalent age, which represents an early phase before the onset of motor impairments. METHODS: We studied 64 preterm infants who were born at <33 weeks gestational age. These infants were divided into three groups: CP, Non-CP (defined as infants with periventricular leukomalacia but having normal motor function), and a Normal group...
May 15, 2018: Brain & Development
https://www.readbyqxmd.com/read/29775884/social-emotional-development-in-very-preterm-infants-during-early-infancy
#14
Peter H Gray, Dawn M Edwards, Ian P Hughes, Margo Pritchard
No abstract text is available yet for this article.
May 15, 2018: Early Human Development
https://www.readbyqxmd.com/read/29775434/births-final-data-for-2016
#15
Joyce A Martin, Brady E Hamilton, Michelle J K Osterman, Anne K Driscoll, Patrick Drake
This report presents 2016 data on U.S. births according to a wide variety of characteristics. Trends in fertility patterns and maternal and infant characteristics are described and interpreted.Descriptive tabulations of data reported on the birth certificates of the 3.95 million births that occurred in 2016 are presented. Data are presented for maternal age, live-birth order, race and Hispanic origin, marital status, tobacco use, prenatal care, source of payment for the delivery, method of delivery, gestational age, birthweight, and plurality...
January 2018: National Vital Statistics Reports
https://www.readbyqxmd.com/read/29773561/postnatal-brain-growth-assessed-by-sequential-cranial-ultrasonography-in-infants-born-30-weeks-gestational-age
#16
R Cuzzilla, A J Spittle, K J Lee, S Rogerson, F M Cowan, L W Doyle, J L Y Cheong
BACKGROUND AND PURPOSE: Brain growth in the early postnatal period following preterm birth has not been well described. This study of infants born at <30 weeks' gestational age and without major brain injury aimed to accomplish the following: 1) assess the reproducibility of linear measures made from cranial ultrasonography, 2) evaluate brain growth using sequential cranial ultrasonography linear measures from birth to term-equivalent age, and 3) explore perinatal predictors of postnatal brain growth...
May 17, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29772833/the-effect-of-increasing-the-protein-content-of-human-milk-fortifier-to-1-8-g-100-ml-on-growth-in-preterm-infants-a-randomised-controlled-trial
#17
Jessica Reid, Maria Makrides, Andrew J McPhee, Michael J Stark, Jacqueline Miller, Carmel T Collins
The aim of this study was to assess the effect of feeding high protein human milk fortifier (HMF) on growth in preterm infants. In this single-centre randomised trial, 60 infants born 28⁻32 weeks' gestation were randomised to receive a higher protein HMF providing 1.8 g protein ( n = 31) or standard HMF providing 1 g protein per 100 mL expressed breast milk (EBM) ( n = 29). The primary outcome was rate of weight gain. Baseline characteristics were similar between groups. There was no difference between high and standard HMF groups for weight gain (mean difference (MD) -14 g/week; 95% CI -32, 4; p = 0...
May 17, 2018: Nutrients
https://www.readbyqxmd.com/read/29772785/comparison-of-human-milk-immunoglobulin-survival-during-gastric-digestion-between-preterm-and-term-infants
#18
Veronique Demers-Mathieu, Mark A Underwood, Robert L Beverly, Søren D Nielsen, David C Dallas
Human milk provides immunoglobulins (Igs) that supplement the passive immune system of neonates; however, the extent of survival of these Igs during gastric digestion and whether this differs between preterm and term infants remains unknown. Human milk, and infant gastric samples at 2 h post-ingestion were collected from 15 preterm (23⁻32 week gestational age (GA)) mother-infant pairs and from 8 term (38⁻40 week of GA) mother-infant pairs within 7⁻98 days postnatal age. Samples were analyzed via ELISA for concentration of total IgA (secretory IgA (SIgA)/IgA), total secretory component (SC/SIgA/SIgM), total IgM (SIgM/IgM), and IgG as well as peptidomics...
May 17, 2018: Nutrients
https://www.readbyqxmd.com/read/29772246/preterm-birth-disrupts-cerebellar-development-by-affecting-granule-cell-proliferation-program-and-bergmann-glia
#19
Igor Y Iskusnykh, Randal K Buddington, Victor V Chizhikov
Preterm birth is a leading cause of long-term motor and cognitive deficits. Clinical studies suggest that some of these deficits result from disruption of cerebellar development, but the mechanisms that mediate cerebellar abnormalities in preterm infants are largely unknown. Furthermore, it remains unclear whether preterm birth and precocious exposure to the ex-utero environment directly disrupt cerebellar development or indirectly by increasing the probability of cerebellar injury, including that resulting from clinical interventions and protocols associated with the care of preterm infants...
May 14, 2018: Experimental Neurology
https://www.readbyqxmd.com/read/29769190/pneumoperitoneum-in-a-neonate-weighing-less-than-500-g-what-do-we-really-know-about-it
#20
Audrienne Sammut, Miguel Soares Oliveira, Claire Jackson, Cristine Sortica da Costa
Pneumoperitoneum in preterm infants is a surgical emergency as it is usually indicative of intestinal perforation. Rare cases of idiopathic pneumoperitoneum have been described in the literature, the underlying causes and pathophysiology of which remain uncertain. We present a case of pneumoperitoneum in an extremely preterm infant with severe growth restriction. This occurred while she was receiving high frequency oscillatory ventilation. She had respiratory distress syndrome with pulmonary interstitial emphysema...
May 16, 2018: BMJ Case Reports
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