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patients and perception and disease

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https://www.readbyqxmd.com/read/28327202/patients-perspective-of-disease-and-medication-adherence-for-type-2-diabetes-in-an-urban-area-in-bangladesh-a-qualitative-study
#1
Sheikh Mohammed Shariful Islam, Tuhin Biswas, Faiz A Bhuiyan, Kamrun Mustafa, Anwar Islam
BACKGROUND: Patients' perspective of diabetes and adherence to its prescribed medications is a significant predictor of glycemic control and overall management of the disease. However, there is a paucity of such information in Bangladesh. This study aimed to explore patients' perspective of diabetes, their experience of taking oral hypoglycemic medications and explore factors that contribute to medication adherence in patients with type 2 diabetes in Bangladesh. METHODS: We conducted in-depth face-to-face interviews with 12 type 2 diabetes patients attending a tertiary hospital in Dhaka city between February and March, 2014...
March 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28326356/effect-of-four-monthly-doses-of-a-human-monoclonal-anti-fgf23-antibody-krn23-on-quality-of-life-in-x-linked-hypophosphatemia
#2
Mary D Ruppe, Xiaoping Zhang, Erik A Imel, Thomas J Weber, Mark A Klausner, Takahiro Ito, Maria Vergeire, Jeffrey S Humphrey, Francis H Glorieux, Anthony A Portale, Karl Insogna, Munro Peacock, Thomas O Carpenter
X-linked hypophosphatemia (XLH) is characterized by lower extremity deformities that lead to bone and/or joint pain that result from decreased renal tubular reabsorption leading to hypophosphatemia caused by elevated levels of fibroblast growth factor 23 (FGF23). OBJECTIVE: Validate the use of SF-36v2 Health Survey (SF-36v2) and the Western Ontario and McMaster Osteoarthritis Index (WOMAC) to measure previously unstudied health-related quality of life (HRQoL) in XLH patients and determine the change in HRQoL before and after treatment with KRN23, a human monoclonal anti-FGF23 antibody...
December 2016: Bone Reports
https://www.readbyqxmd.com/read/28325166/color-perception-differentiates-alzheimer-s-disease-ad-from-vascular-dementia-vad-patients
#3
N A Arnaoutoglou, M Arnaoutoglou, P Nemtsas, V Costa, S J Baloyannis, K P Ebmeier
BACKGROUND: Alzheimer's Disease (AD) and Vascular Dementia (VaD) are the most common causes of dementia in older people. Both diseases appear to have similar clinical symptoms, such as deficits in attention and executive function, but specific cognitive domains are affected. Current cohort studies have shown a close relationship between αβ deposits and age-related macular degeneration (Johnson et al., 2002; Ratnayaka et al., 2015). Additionally, a close link between the thinning of the retinal nerve fiber (RNFL) and AD patients has been described, while it has been proposed that AD patients suffer from a non-specific type of color blindness (Pache et al...
March 22, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28319316/barriers-to-the-management-of-obstructed-defecation-according-to-colorectal-surgeons
#4
Nagham Al-Mozany, Caroline Wright, Greg O'Grady, Christopher J Young, Michael J Solomon
INTRODUCTION: Obstructive defecation (OD) has a high prevalence and disease impact, however patients often experience suboptimal management. This problem reflects the complex pathophysiology of OD, as well as health service delivery factors. This study aimed to identify factors acting as a barrier to effective OD management as perceived by specialist colorectal surgeons treating this disorder. METHOD: A postal questionnaire was administered to a bi-national sampling of colorectal specialists in Australia and New Zealand who were registered with their specialty society...
March 20, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28317607/nutritional-aspects-of-dysphagia-management
#5
C Gallegos, E Brito-de la Fuente, P Clavé, A Costa, G Assegehegn
This chapter describes the nutritional aspects of dysphagia management by starting with the definition of these two conditions (dysphagia and malnutrition) that share three main clinical characteristics: (a) their prevalence is very high, (b) they can lead to severe complications, and (c) they are frequently underrecognized and neglected conditions. From an anatomical standpoint, dysphagia can result from oropharyngeal and/or esophageal causes; from a pathophysiological perspective, dysphagia can be caused by organic or structural diseases (either benign or malignant) or diseases causing impaired physiology (mainly motility and/or perception disorders)...
2017: Advances in Food and Nutrition Research
https://www.readbyqxmd.com/read/28316939/application-of-established-pathophysiologic-processes-brings-greater-clarity-to-diagnosis-and-treatment-of-hyponatremia
#6
EDITORIAL
John K Maesaka, Louis J Imbriano, Nobuyuki Miyawaki
Hyponatremia, serum sodium < 135 mEq/L, is the most common electrolyte abnormality and is in a state of flux. Hyponatremic patients are symptomatic and should be treated but our inability to consistently determine the causes of hyponatremia has hampered the delivery of appropriate therapy. This is especially applicable to differentiating syndrome of inappropriate antidiuresis (SIAD) from cerebral salt wasting (CSW) or more appropriately, renal salt wasting (RSW), because of divergent therapeutic goals, to water-restrict in SIAD and administer salt and water in RSW...
March 6, 2017: World Journal of Nephrology
https://www.readbyqxmd.com/read/28316774/glutathione-metabolism-in-the-prefrontal-brain-of-adults-with-high-functioning-autism-spectrum-disorder-an-mrs-study
#7
Dominique Endres, Ludger Tebartz van Elst, Simon A Meyer, Bernd Feige, Kathrin Nickel, Anna Bubl, Andreas Riedel, Dieter Ebert, Thomas Lange, Volkmar Glauche, Monica Biscaldi, Alexandra Philipsen, Simon J Maier, Evgeniy Perlov
BACKGROUND: Autism spectrum disorder (ASD) is a neurodevelopmental disease characterized by difficulties in social communication, unusually restricted, repetitive behavior and interests, and specific abnormalities in language and perception. The precise etiology of ASD is still unknown and probably heterogeneous. In a subgroup of patients, toxic environmental exposure might lead to an imbalance between oxidative stress and anti-oxidant systems. Previous serum and postmortem studies measuring levels of glutathione (GSH), the main cellular free radical scavenger in the brain, have supported the hypothesis that this compound might play a role in the pathophysiology of autism...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28316572/eccentric-ergometer-training-promotes-locomotor-muscle-strength-but-not-mitochondrial-adaptation-in-patients-with-severe-chronic-obstructive-pulmonary-disease
#8
Norah J MacMillan, Sophia Kapchinsky, Yana Konokhova, Gilles Gouspillou, Riany de Sousa Sena, R Thomas Jagoe, Jacinthe Baril, Tamara E Carver, Ross E Andersen, Ruddy Richard, Hélène Perrault, Jean Bourbeau, Russell T Hepple, Tanja Taivassalo
Eccentric ergometer training (EET) is increasingly being proposed as a therapeutic strategy to improve skeletal muscle strength in various cardiorespiratory diseases, due to the principle that lengthening muscle actions lead to high force-generating capacity at low cardiopulmonary load. One clinical population that may particularly benefit from this strategy is chronic obstructive pulmonary disease (COPD), as ventilatory constraints and locomotor muscle dysfunction often limit efficacy of conventional exercise rehabilitation in patients with severe disease...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28315610/sensory-processing-in-huntington-s-disease
#9
Ana Mirallave, Merche Morales, Christopher Cabib, Esteban J Muñoz, Pilar Santacruz, Xavier Gasull, Josep Valls-Sole
OBJECTIVE: An intriguing electrophysiological feature of patients with Huntington's disease (HD) is the delayed latency and decreased amplitude of somatosensory long-latency evoked potentials (LLeps). We investigated whether such dysfunction was associated with delayed conscious perception of the sensory stimulus. METHODS: Sixteen HD patients and 16 control subjects faced a computer screen showing the Libet's clock (Libet et al., 1983). In Rest trials, subjects had to memorize the position of the clock handle at perception of either electrical or thermal stimuli (AW)...
February 14, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28315129/influenza-vaccination-coverage-among-polish-patients-with-chronic-diseases
#10
Aneta Nitsch-Osuch, Izabella Gołębiak, Dorota Wyszkowska, Renata Rosińska, Lidia Kargul, Bożena Szuba, Piotr Tyszko, Lidia Brydak
Patients at a high-risk of severe influenza, because of their underlying health disorders, are recommended to receive a seasonal influenza vaccination. In Poland, influenza coverage rate in the general population is very low (3.4 %). However, there is little known about the coverage rate among high-risk patients. The aim of this study was to describe a general knowledge, perception, and influenza vaccination coverage rate among Polish patients with enhanced risk for influenza. We conducted a self-reported survey among 500 patients with chronic disorders: 120 pulmonary, 80 hemodialyzed, 100 thyroid cancer, and 200 cardiovascular patients...
March 18, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28314139/patients-experiences-of-atrial-fibrillation-and-non-vitamin-k-antagonist-oral-anticoagulants-noacs-and-their-educational-needs-a-qualitative-study
#11
Danielle E Clarkesmith, Gregory Y H Lip, Deirdre A Lane
PURPOSE: Qualitative research on atrial fibrillation (AF) patient's experiences and perceptions of taking the non-vitamin K antagonist oral anticoagulants (NOACs) for stroke prevention is limited. This study explores patients' experiences of dabigatran and their recommendations for development of educational materials. PATIENTS AND METHODS: Semi-structured individual interviews with 8 warfarin-naive and 8 warfarin-experienced AF patients, using qualitative deductive thematic analysis...
March 7, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28306611/the-patients-perspective-hematological-cancer-patients-experiences-of-adverse-events-as-part-of-care
#12
Jamie Bryant, Mariko Carey, Rob Sanson-Fisher, Heidi Turon, Andrew Wei, Bryone Kuss
OBJECTIVE: To describe in a sample of patients with a confirmed diagnosis of a hematological cancer: (a) the proportion who self-report experiencing an unexpected adverse event as part of their care; (b) how the adverse event was handled by the health-care organization; and (c) the sociodemographic, disease, and treatment characteristics associated with experiencing an adverse event. DESIGN: Cross sectional survey. SETTING: Three Australian hematological oncology treatment centers...
March 17, 2017: Journal of Patient Safety
https://www.readbyqxmd.com/read/28300952/the-individual-with-epilepsy-perceptions-about-the-disease-and-implications-on-quality-of-life
#13
Christiane Del Claro Hopker, Ana Paula Berberian, Gisele Massi, Mariluci Hautsch Willig, Rita Tonocchi
Purpose: The present study aims to analyze the perceptions of individuals with epilepsy about the disease and its impact in their quality of life (QoL). Methods: This is a cross-sectional, qualitative and quantitative study conducted in a tertiary referral hospital associated with the Brazilian National Health System (SUS). Data were collected from 30 individuals with diagnosis of refractory temporal lobe epilepsy (RTLE). The study participants responded to a questionnaire to collect sociodemographic and clinical data, as well as their perceptions about the disease...
March 9, 2017: CoDAS
https://www.readbyqxmd.com/read/28299421/evaluation-of-sexual-dysfunction-in-female-patients-presenting-with-faecal-incontinence-or-defecation-disorder
#14
Gianluca Pellino, Lisa Ramage, Constantinos Simillis, Oliver Warren, Christos Kontovounisios, Emile Tan, Paris Tekkis
PURPOSE: Female patients with pelvic floor diseases may suffer from several sexual disorders and sexual life impairments. The aim of this manuscript was to evaluate sexual dysfunction in female patients presenting with faecal incontinence (FI) and defecation disorder (DD). METHODS: A retrospective review was performed of a prospectively collected database of sexually active women referred to the pelvic floor clinic, who completed the Pelvic Organ Prolapse/Incontinence Sexual Questionnaire-12 (PISQ-12) at first visit...
March 15, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28299161/healthcare-professionals-awareness-knowledge-attitudes-perceptions-and-beliefs-about-ebola-at-gondar-university-hospital-northwest-ethiopia-a-cross-sectional-study
#15
Tamrat Befekadu Abebe, Akshaya Srikanth Bhagavathula, Yonas Getaye Tefera, Akram Ahmad, Muhammad Umair Khan, Sewunet Admasu Belachew, Brandon Brown, Tadesse Melaku Abegaz
A poor understanding of Ebola Virus Disease (EVD) among Health Care Professionals (HCPs) may put our lives at risk. We aimed to assess the awareness, knowledge, attitudes, perceptions, beliefs of HCPs towards Ebola at Gondar University Hospital (GUH) in Northwest Ethiopia. We conducted a hospital based, cross-sectional survey among 245 randomly selected HCPs working at GUH from August-October, 2015. A validated, self-administered questionnaire was used to collect the data. We calculated descriptive statistics with P<0...
December 31, 2016: Journal of Public Health in Africa
https://www.readbyqxmd.com/read/28297040/repair-of-total-tractional-retinal-detachment-in-norrie-disease-report-of-technique-and-successful-surgical-outcome
#16
Bozho Todorich, Aristomenis Thanos, Yoshihiro Yonekawa, Antonio Capone
Norrie disease is a rare, but devastating cause of pediatric retinal detachment, universally portending a poor visual prognosis. This paper describes successful surgical management of an infant with total retinal detachment associated with Norrie disease mutation. The infant was a full-term white male who presented with bilateral total funnel retinal detachments (RDs). He underwent genetic testing, which demonstrated single-point mutation 133 G>A transition in exon 2 of the NDP gene. The retinal detachment was managed with translimbal iridectomy, lensectomy, capsulectomy, and vitrectomy...
March 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28297036/wide-field-landers-keratoprothesis-in-various-combined-corneal-and-vitreoretinal-problems-twelve-month-results
#17
Ziya Kapran, Abdullah Ozkaya, Gurkan Erdogan, Yalcin Karakucuk, Tugba Aydogan Gezginaslan, Irfan Perente, Muhittin Taskapili
BACKGROUND AND OBJECTIVE: To investigate the outcomes of combined pars plana vitrectomy (PPV), transient keratoprosthesis (TKP), and penetrating keratoplasty (PKP) in patients with coexisting corneal and vitreoretinal diseases. PATIENTS AND METHODS: Patients who underwent PPV, TKP, and PKP were included. The main outcome measures were change in visual acuity (VA), clarity of the graft, and retinal attachment. RESULTS: Twenty eyes were included...
March 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28295744/contributing-factors-for-therapeutic-diet-adherence-in-patients-receiving-haemodialysis-treatment-an-integrative-review
#18
REVIEW
Lissete González Oquendo, José Miguel Morales Asencio, Candela Bonill de Las Nieves
AIMS AND OBJECTIVES: The objective of this integrative review is to identify the factors that contribute to diet adherence in people suffering from kidney disease who are receiving haemodialysis treatment. BACKGROUND: Adherence to the therapeutic regimen determines therapeutic success, quality of life, and survival in patients on haemodialysis. Lack of diet adherence ranges from 25 to 86% in patients receiving haemodialysis treatment and affects patient morbidity and mortality...
March 15, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28295206/molecular-clinical-and-neuropsychological-study-in-31-patients-with-kabuki-syndrome-and-kmt2d-mutations
#19
Natacha Lehman, Anne Claire Mazery, Antoine Visier, Clarisse Baumann, Dominique Lachesnais, Yline Capri, Annick Toutain, Sylvie Odent, Myriam Mikaty, Cyril Goizet, Emmanuelle Taupiac, Marie Line Jacquemont, Elodie Sanchez, Elise Schaefer, Vincent Gatinois, Laurence Faivre, Delphine Minot, Honorine Kayirangwa, Kim-Hanh Le Qang Sang, Nathalie Boddaert, Sophie Bayard, Didier Lacombe, Sébastien Moutton, Isabelle Touitou, Marlène Rio, Jeanne Amiel, Stanislas Lyonnet, Damien Sanlaville, Marie Christine Picot, David Geneviève
Kabuki syndrome (KS - OMIM 147920) is a rare developmental disease characterized by the association of multiple congenital anomalies and intellectual disability. This study aimed to investigate intellectual performance in children with Kabuki syndrome and link the performance to several clinical features and molecular data. We recruited 31 children with KMT2D mutations who were 6 to 16 years old. They all completed the Weschler Intelligence Scale for Children, fourth edition. We calculated all indexes: the Full Scale Intellectual Quotient (FSIQ), Verbal Comprehension Index (VCI), Perceptive Reasoning Index (PRI), Processing Speed Index (PSI), and Working Memory Index (WMI)...
March 14, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/28294545/oral-health-related-quality-of-life-depending-on-oral-health-and-specific-factors-in-patients-after-lung-transplantation
#20
Gerhard Schmalz, Horst Wendorff, Anna Marcinkowski, Gerhard Weinreich, Helmut Teschler, Rainer Haak, Urte Sommerwerck, Dirk Ziebolz
INTRODUCTION: Patients after lung transplantation (LuTx) were found to present oral health deficiencies. The investigation of potentially underlying or influencing factors appears to be of clinical relevance. OBJECTIVES: Aim of this study was to evaluate the oral health related quality of life (OHRQoL) in a group of patients after LuTx and compare this to a healthy control group (HC). Furthermore, the influence of dental and periodontal condition, as well as specific factors like immunosuppression, time after LuTx and causal underlying disease should be investigated...
March 13, 2017: Clinical Respiratory Journal
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