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https://www.readbyqxmd.com/read/28727796/effects-of-health-risk-assessment-and-counselling-on-physical-activity-in-older-people-a-pragmatic-randomised-trial
#1
Anna Marie Herghelegiu, André Moser, Gabriel Ioan Prada, Stephan Born, Matthias Wilhelm, Andreas E Stuck
BACKGROUND: Interventions to increase physical activity (PA) among older community-dwelling adults may be enhanced by using multidimensional health risk assessment (HRA) as a basis for PA counselling. METHODS: The study was conducted among nondisabled but mostly frail persons 65 years of age and older at an ambulatory geriatric clinic in Bucharest, Romania. From May to July 2014, 200 participants were randomly allocated to intervention and control groups. Intervention group participants completed an initial HRA questionnaire and then had monthly counselling sessions with a geriatrician over a period of six months that were aimed at increasing low or maintaining higher PA...
2017: PloS One
https://www.readbyqxmd.com/read/28723712/the-role-of-oncogenic-hpv-determination-for-diagnosis-of-high-grade-anal-intraepithelial-neoplasia-in-hiv-infected-msm
#2
Joaquin Burgos, J Hernández-Losa, S Landolfi, A Guelar, Mªc Dinares, J Villar, J Navarro, E Ribera, V Falcó, A Curran
OBJECTIVE: To assess the oncogenic human papillomavirus (HPV) determination and the co-testing HPV and anal cytology value to detect high-grade anal intraepithelial neoplasia (HGAIN) in a cohort of HIV-MSM. DESIGN AND METHODS: Prospective study of HIV-infected MSM who underwent screening for anal dysplasia. Screening program includes anal cytology, HPV testing, and high-resolution anoscopy (HRA) at each visit. Histological samples were obtained if suspicious lesions were revealed by HRA...
July 18, 2017: AIDS
https://www.readbyqxmd.com/read/28715928/lack-of-evidence-the-anti-stepwise-introduction-of-metal-on-metal-hip-replacements
#3
Aleksi Reito, Lari Lehtovirta, Olli Lainiala, Keijo Mäkelä, Antti Eskelinen
Background and purpose - Orthopedics and especially joint replacement surgery have had more than their fair share of unsuccessful innovations that have violated widely endorsed principles for the introduction of new surgical innovations. We aimed to investigate (1) the trends in the use of the Birmingham Hip Resurfacing (BHR), the ASR hip resurfacing (ASR HRA) and the ASR XL total hip replacement (ASR XL THR) system with very different market approval processes and (2) whether their use was corroborated by clinical trials published in the peer-reviewed literature...
July 18, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28708673/the-association-of-employee-engagement-at-work-with-health-risks-and-presenteeism
#4
Wayne N Burton, Chin-Yu Chen, Xingquan Li, Alyssa B Schultz
INTRODUCTION: Employee engagement is a key factor in work performance and employee retention. The current study seeks to examine the relationship between employee engagement and health risks and productivity. METHODS: In 2012, employees of a global financial services corporation participated in a health risk appraisal (HRA) which measured employee engagement, health risks, and on-the-job productivity loss (presenteeism). Three engagement categories were created...
July 13, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28704629/enhanced-hazard-analysis-and-risk-assessment-for-human-in-the-loop-systems
#5
David Kaber, Maryam Zahabi
OBJECTIVE: The objective of this study was to enhance the existing system hazard analysis (SHA) technique by introducing the concepts of human and automation reliability quantification as well as fuzzy classification of system risks. These enhancements led to formulation of a new overall system risk-reliability score. BACKGROUND: Many system safety analysis methods focus on individual physical component failure. Some human reliability analyses (HRA) consider human-automation interaction in determining system failure rates...
August 2017: Human Factors
https://www.readbyqxmd.com/read/28695429/cryotherapy-for-intra-and-perianal-high-grade-squamous-intraepithelial-lesions-in-hiv-positive-men-who-have-sex-with-men
#6
Matthijs L Siegenbeek van Heukelom, Karien C M Gosens, Jan M Prins, Henry J C de Vries
BACKGROUND: Available treatment options for anal high-grade squamous intraepithelial lesions (HSIL) in HIV-positive men who have sex with men (MSM) are limited by low response rates and frequent recurrences. Cryotherapy is an established therapeutic option for several pre-malignant skin disorders. METHODS: This retrospective, non-randomized study included HIV-positive MSM who received intra- and/or perianal HSIL cryotherapy treatment between 30 December 2008 and 23 April 2015...
July 10, 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28682089/associations-among-psychological-distress-high-risk-activism-and-conflict-between-ethnic-racial-and-sexual-minority-identities-in-lesbian-gay-bisexual-racial-ethnic-minority-adults
#7
Carlos E Santos, Rachel A VanDaalen
In this brief report, we present results from a study exploring the associations of high-risk activism (HRA) orientation in lesbian, gay, and bisexual (LGB) issues; HRA orientation in racial/ethnic issues; conflicts in allegiances (CIA) between one's ethnic-racial and sexual minority identities; and anxiety among LGB racial/ethnic minority adults. A racially and ethnically diverse sample of 208 LGB racial/ethnic minority adults (age: M = 27.52, SD = 8.76) completed an online survey. Bivariate correlations showed that HRA orientation in LGB and in racial/ethnic issues, as well as CIA, were each positively associated with anxiety...
July 6, 2017: Journal of Counseling Psychology
https://www.readbyqxmd.com/read/28667225/using-patient-reported-outcome-measures-proms-to-promote-quality-of-care-and-safety-in-the-management-of-patients-with-advanced-chronic-kidney-disease-pro-track-project-a-mixed-methods-project-protocol
#8
Olalekan Lee Aiyegbusi, Derek Kyte, Paul Cockwell, Tom Marshall, Mary Dutton, Anita Slade, Neil Marklew, Gary Price, Rav Verdi, Judi Waters, Keeley Sharpe, Melanie Calvert
INTRODUCTION: Advanced chronic kidney disease (CKD) has a major effect on the quality of life and health status of patients and requires accurate and responsive management. The use of electronic patient-reported outcome measures (ePROMs) could assist patients with advanced pre-dialysis CKD, and the clinicians responsible for their care, by identifying important changes in symptom burden in real time. We report the protocol for 'Using Patient-Reported Outcome measures (PROMs) to promote quality of care and safety in the management of patients with Advanced Chronic Kidney Disease' (PRO-trACK) project, which will explore the feasibility and validity of an ePROM system for use in patients with advanced CKD...
June 30, 2017: BMJ Open
https://www.readbyqxmd.com/read/28663390/risk-factors-for-wear-related-failures-after-hip-resurfacing-in-patients-with-a-low-contact-patch-to-rim-distance
#9
H C Amstutz, M J Le Duff, S K Bhaurla
AIMS: A contact patch to rim (CPR) distance of < 10 mm has been associated with edge-loading and excessive wear. However, not all arthroplasties with a low CPR distance show problems with wear. Therefore, CPR distance may not be the only variable affecting the post-operative metal ion concentrations. PATIENTS AND METHODS: We used multiple logistic regression to determine what variables differed between the patients who had high and low cobalt (CoS) and chromium (CrS) serum ion concentrations within a cohort of patients with low (< 10 mm) CPR distances...
July 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28660146/bile-cast-nephropathy-in-patients-with-acute-kidney-injury-due-to-hepatorenal-syndrome-a-postmortem-kidney-biopsy-study
#10
Suman Lata Nayak, Manoj Kumar, Chhagan Bihari, Archana Rastogi
Background and Aims: The role of bile cast nephropathy (BCN) in pathogenesis of hepatorenal syndrome (HRS) in decompensated cirrhosis and acute on chronic liver failure (ACLF) is unknown. This study aimed to determine the frequency of BCN detected on postmortem renal biopsy among patients with decompensated cirrhosis and ACLF who had been admitted with acute kidney injury due to HRS (HRA-AKI) and expired during that hospitalization. Methods: One-hundred-twenty-seven postmortem renal biopsies with adequate size (>1 cm in length) were included for analysis...
June 28, 2017: Journal of Clinical and Translational Hepatology
https://www.readbyqxmd.com/read/28616243/a-global-cross-cultural-study-examining-the-relationship-between-employee-health-risk-status-and-work-performance-metrics
#11
Ana Howarth, Jose Quesada, Peter R Mills
BACKGROUND: Health risk assessments (HRA) are used by many organisations as a basis for developing relevant and targeted employee health and well-being interventions. However, many HRA's have a western-centric focus and therefore it is unclear whether the results can be directly extrapolated to those from non-western countries. More information regarding the differences in the associations between country status and health risks is needed along with a more global perspective of employee health risk factors and well-being overall...
2017: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28613142/mutations-in-the-fusion-protein-heptad-repeat-domains-of-human-metapneumovirus-impact-on-the-formation-of-syncytia
#12
Julia Dubois, Marie-Hélène Cavanagh, Olivier Terrier, Marie-Ève Hamelin, Bruno Lina, Rong Shi, Manuel Rosa-Calatrava, Guy Boivin
Human metapneumovirus (HMPV) is an important cause of respiratory tract infections. The mechanism by which its fusion (F) protein is responsible for variable cytopathic effects in vitro remains unknown. We aligned the F sequences of the poorly fusogenic B2/CAN98-75 strain and the hyperfusogenic A1/C-85473 strain and identified divergent residues located in the two functional heptad repeats domains (HRA and HRB). We generated recombinant viruses by inserting the mutations N135T-G139N-T143K-K166E-E167D in HRA and/or K479R-N482S in HRB, corresponding to swapped sequences from C-85473, into CAN98-75 background and investigated their impact on in vitro phenotype and fusogenicity...
June 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28588733/differences-in-the-sensitivity-of-ovarian-cancer-to-photodynamic-therapy-and-the-mechanisms-for-those-differences
#13
Yoshihito Yokoyama, Tatsuhiko Shigeto, Rie Miura, Asami Kobayashi, Makito Mizunuma, Aisa Yamauchi, Masayuki Futagami, Hideki Mizunuma
Protoporphyrin IX (PpIX) levels are crucial to the antitumor action of photodynamic therapy (PDT). In the present study, the underling molecular mechanisms for the variation in PpIX levels in ovarian cancer cells were investigated. Five ovarian cancer cell lines were subcutaneously grafted onto the backs of nude mice. Once tumors had developed, 5-aminolevulinic acid methyl ester hydrochloride (methyl-ALA) was administered intraperitoneally and the tumor was irradiated twice/week. PpIX levels in the tumor were assayed using high-performance liquid chromatography...
June 2017: Oncology Letters
https://www.readbyqxmd.com/read/28554627/heavy-metal-exposure-from-cooked-rice-grain-ingestion-and-its-potential-health-risks-to-humans-from-total-and-bioavailable-forms-analysis
#14
S M Praveena, N A Omar
Heavy metal in rice studies has attracted a greater concern worldwide. However, there have been limited studies on marketed rice samples although it represents a vital ingestion portion for a real estimation of human health risk. This study was aimed to determine both total and bioaccessible of trace elements and heavy metals (Cd, Cr, Cu, Co, Al, Zn, As, Pb and Fe) in 22 varieties of cooked rice using an inductively coupled plasma-optical emission spectroscopy. Both total and bioaccessible of trace elements and heavy metals were digested using closed-nitric acid digestion and Rijksinstituut voor Volksgezondheid en Milieu (RIVM) in vitro digestion model, respectively...
November 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28543395/contact-urticaria-syndrome-with-ige-antibody-against-a-cefotiam-unique-structure-evoked-by-nonapparent-exposure-to-cefotiam
#15
S Takahagi, A Tanaka, K Iwamoto, K Ishii, M Hide
A 26-year-old woman presented with recurrent attacks of widespread urticaria and systemic symptoms. The patient was a nurse, and the attacks occurred only in her workplace, without an apparent trigger. A patch test to cefotiam (CTM) induced an immediate skin reaction. ELISA detected the patient's serum IgE antibody binding to CTM conjugated with human serum albumin (CTM-HSA), and her basophils released histamine in response to CTM-HSA in a histamine release assay (HRA). Both reactions in ELISA and HRA were inhibited by pretreatment of the patient's serum or basophils with cefotiam...
May 22, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28535717/association-of-wage-with-employee-participation-in-health-assessments-and-biometric-screening
#16
Bruce W Sherman, Carol Addy
PURPOSE: To understand differences in health risk assessment (HRA) and biometric screening participation rates among benefits-enrolled employees in association with wage category. DESIGN: Cross-sectional analysis of employee eligibility file and health benefits (wellness and claims) data. SETTING: Data from self-insured employers participating in the RightOpt private exchange (Conduent HR Services) during 2014. PARTICIPANTS: Active employees from 4 companies continuously enrolled in health insurance for which wage data were available...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/28516424/differing-developmental-trajectories-in-heart-rate-responses-to-speech-stimuli-in-infants-at-high-and-low-risk-for-autism-spectrum-disorder
#17
Katherine L Perdue, Laura A Edwards, Helen Tager-Flusberg, Charles A Nelson
We investigated heart rate (HR) in infants at 3, 6, 9, and 12 months of age, at high (HRA) and low (LRC) familial risk for ASD, to identify potential endophenotypes of ASD risk related to attentional responses. HR was extracted from functional near-infrared spectroscopy recordings while infants listened to speech stimuli. Longitudinal analysis revealed that HRA infants and males generally had lower baseline HR than LRC infants and females. HRA infants showed decreased HR responses to early trials over development, while LRC infants showed increased responses...
August 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28510514/door-is-open-for-hras-to-make-a-comeback
#18
Jan Greene
For four years, businesses that wanted to reimburse employees for their health insurance premiums rather than buying their coverage for them were told that that was no longer allowed under the ACA. But the health reimbursement arrangement (HRA) is back, brought back to life by provisions tucked into last year's 21st Century Cure Act.
March 2017: Managed Care
https://www.readbyqxmd.com/read/28418575/effects-of-previous-osteotomy-on-outcome-of-hip-resurfacing-arthroplasty
#19
Harlan Cabot Amstutz, Michel Jean Le Duff
The effect of previous conservative surgeries on the outcome of metal-on-metal hip resurfacing arthroplasty (HRA) has not been studied. This study compared postoperative clinical scores and survivorship results of hips with and without previous osteotomies in a population of patients who underwent HRA. A total of 1101 patients (1375 hips) with a mean age of 51.3 years at the time of surgery underwent HRA at a single center. Sixty-nine patients had undergone prior surgery on the operated hip including 14 osteotomies (1 pelvic, 6 femoral, and 7 combined pelvic and femoral osteotomies)...
July 1, 2017: Orthopedics
https://www.readbyqxmd.com/read/28416973/the-utility-of-atrial-pacing-for-identifying-the-electrical-breakthrough-sites-between-the-left-atrium-and-pulmonary-veins
#20
Shinya Sugiura, Koji Matsuoka, Hideki Noda, Naoya Kurata, Misa Uemori, Hirokazu Shioji, Akihiro Takasaki, Takafumi Koji, Takashi Tanigawa, Masaaki Ito
BACKGROUND: Circumferential pulmonary vein (PV) isolation for atrial fibrillation (AF) is occasionally difficult to achieve because electrical breakthrough sites (EBSs) between the left atrium (LA) and PVs cannot be identified during ablation especially in the carina regions. METHODS: The left PVs (Lt.PVs) of 60 AF patients and the right PVs (Rt.PVs) of 37 patients undergoing PV isolation were studied. When PV isolation was not achieved after the initial circumferential PV isolation, atrial pacing was repeatedly performed from the distal coronary sinus (CSd) and high right atrium (HRA), and the time interval from the stimulus to the earliest PV potential (stimulus-PV interval) was measured using circular mapping catheters at each PV until PV isolation was achieved...
April 2017: Journal of Arrhythmia
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