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https://www.readbyqxmd.com/read/28285976/high-altitude-illness-in-pilgrims-after-rapid-ascent-to-4380%C3%A2-m
#1
Ken Zafren, Matiram Pun, Nirajan Regmi, Gobinda Bashyal, Bhuwan Acharya, Subarna Gautam, Sujan Jamarkattel, Shankar Raj Lamichhane, Suman Acharya, Buddha Basnyat
BACKGROUND: The goal of the study was to characterize high altitude illness in Nepali pilgrims. METHODS: We kept standardized records at the Himalayan Rescue Association (HRA) Temporary Health Camp at Gosainkund Lake (4380 m) in the Nepal Himalaya during the annual Janai Purnima Festival in 2014. Records included rate of ascent and Lake Louise Score (LLS). We defined High Altitude Headache (HAH) as headache alone or LLS = 2. Acute Mountain Sickness (AMS) was LLS≥3...
March 9, 2017: Travel Medicine and Infectious Disease
https://www.readbyqxmd.com/read/28252530/risk-factors-of-high-grade-anal-intraepithelial-neoplasia-recurrence-in-hiv-infected-men-who-have-sex-with-men
#2
Joaquin Burgos, Adria Curran, Stefania Landolfi, Ana Guelar, Lucia Miguel, MCarmen Dinares, Judith Villar, Jordi Navarro, Javier Hernandez-Losa, Vicenç Falcó
OBJECTIVE: To assess risk factors of high-grade anal intraepithelial neoplasia (HGAIN) recurrence in a cohort of HIV-infected men who have sex with men (MSM). DESIGN AND METHODS: Consecutive HIV-infected 100 MSM with a history of successfully treated intra-anal HGAIN with electrocautery were followed with anal cytology, human papillomavirus (HPV) determination, and high-resolution anoscopy (HRA) at 3-6 month intervals. HGAIN recurrence was analyzed using Kaplan-Meier analysis...
March 1, 2017: AIDS
https://www.readbyqxmd.com/read/28239321/determining-the-optimal-surveillance-interval-after-a-colonoscopic-polypectomy-for-the-korean-population
#3
Jung Lok Lee, Jae Myung Cha, Hye Min Lee, Jung Won Jeon, Min Seob Kwak, Jin Young Yoon, Hyun Phil Shin, Kwang Ro Joo, Joung Il Lee, Dong Il Park
BACKGROUND/AIMS: Western surveillance strategies cannot be directly adapted to the Korean population. The aim of this study was to estimate the risk of metachronous neoplasia and the optimal surveillance interval in the Korean population. METHODS: Clinical and pathological data from index colonoscopy performed between June 2006 and July 2008 and who had surveillance colonoscopies up to May 2015 were compared between low- and high-risk adenoma (LRA and HRA) groups...
January 2017: Intestinal Research
https://www.readbyqxmd.com/read/28237425/aqueous-angiography-in-living-nonhuman-primates-shows-segmental-pulsatile-and-dynamic-angiographic-aqueous-humor-outflow
#4
Alex S Huang, Meng Li, Diya Yang, Huaizhou Wang, Ningli Wang, Robert N Weinreb
PURPOSE: To evaluate the feasibility of safely performing aqueous angiography in intact eyes of living nonhuman primates (NHPs) for evaluating aqueous humor outflow and segmental patterns. DESIGN: Cross-sectional, observational study. SUBJECTS: Six nonhuman primates. METHODS: Aqueous angiography was performed in 6 nonhuman primates. After anesthesia, an anterior chamber (AC) maintainer was placed through a temporal 1-mm side-port wound...
February 22, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28229612/preliminary-results-of-a-screening-program-for-anal-cancer-and-its-precursors-for-hiv-infected-men-who-have-sex-with-men-in-vigo-spain
#5
Mauricio Iribarren Díaz, Antonio Ocampo Hermida, Joaquín González-Carreró Fojón, Rebeca Longueira Suárez, Alberto Rivera Gallego, Enrique Casal Núñez, Antón Ocampo Álvarez, Edward Cachay
BACKGROUND: Men who have sex with men (MSM) infected with human immunodeficiency virus (HIV) have the highest risk of developing anal cancer (AC). The objective of this study was to describe our screening implementation program in this population, and report the prevalence of human papillomavirus (HPV) anal infection, and cytological and histological findings in a Spanish medium-size community (Vigo, Spain). METHOD: Prospective cohort analysis of 240 HIV-infected MSM...
February 23, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28218371/adverse-reaction-to-metal-debris-in-a-consecutive-series-of-durom%C3%A2-hip-resurfacing-pseudotumour-incidence-and-metal-ion-concentration
#6
Albrecht Hartmann, Jan-Dirk Kieback, Jörg Lützner, Klaus-Peter Günther, Jens Goronzy
INTRODUCTION: The aim of this study was to evaluate the incidence of adverse reactions to metal debris (ARMD) in a consecutive series of DUROM™ Hip Resurfacing Arthroplasty (HRA) at mid-term follow-up. METHODS: Between October 2003 and March 2007 a total of 134 consecutive DUROM™ HRA in 121 patients were performed at our institution. Follow-up could be obtained in 101 unrevised patients (83%) at a mean time of 8.51 ± 0.97 years postoperatively and included patient-related outcome measurement, plain radiographs, MARS-MRI as well as whole blood metal ion assessment...
February 8, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28174606/lateralization-of-erps-to-speech-and-handedness-in-the-early-development-of-autism-spectrum-disorder
#7
Kayla H Finch, Anne M Seery, Meagan R Talbott, Charles A Nelson, Helen Tager-Flusberg
BACKGROUND: Language is a highly lateralized function, with typically developing individuals showing left hemispheric specialization. Individuals with autism spectrum disorder (ASD) often show reduced or reversed hemispheric lateralization in response to language. However, it is unclear when this difference emerges and whether or not it can serve as an early ASD biomarker. Additionally, atypical language lateralization is not specific to ASD as it is also seen more frequently in individuals with mixed- and left-handedness...
2017: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/28166123/prevalence-of-metabolic-syndrome-in-an-employed-population-as-determined-by-analysis-of-three-data-sources
#8
Ron Z Goetzel, Karen Kent, Rachel Mosher Henke, Cory Pack, Malinda D'Arco, Jordana Thomas, James Luckett, Traci Arthur-Hartranft
OBJECTIVE: The aim of this study was to compare estimates of the prevalence and incidence of metabolic syndrome (MetS) using various data sources. METHODS: We integrated health risk assessment (HRA), claims, and biometric screening data from Lockheed Martin Corporation. We measured the extent to which MetS risk factors measured using HRA and medical claims correlated with biometric screening data. RESULTS: Using biometric data, 24.9% of employees were identified as having MetS...
February 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28141783/prevalence-of-anal-hpv-and-anal-dysplasia-in-hiv-infected-women-from-johannesburg-south-africa
#9
Bridgette J Goeieman, Cynthia S Firnhaber, Eefje Jong, Pam Michelow, Avril Swarts, Anna-Lise Williamson, Bruce Allan, Jennifer S Smith, Patricia Kegorilwe, Timothy J Wilkin
BACKGROUND: Anal cancer is a relatively common cancer among HIV-infected populations. There are limited data on the prevalence of anal high-risk human papillomavirus (HR-HPV) infection and anal dysplasia in HIV-infected women from resource-constrained settings. METHODS: A cross-sectional study of HIV-infected women age 25-65 recruited from an HIV clinic in Johannesburg, South Africa. Cervical and anal swabs were taken for conventional cytology and HR-HPV testing...
January 30, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28135858/perception-interpretation-and-impact-of-health-risk-appraisal-feedback
#10
Kathryn Berlin, Vicki Simpson, Gerry Hyner
One mandate of the Affordable Care Act is continued support of workplace wellness programs. A tool used to encourage behavior change is a health risk appraisal (HRA). However, research indicates there is limited benefit to HRAs unless supported by additional health interventions. The purpose of these two pilot studies was to examine effects of the individual HRA personalized feedback, including the perceived value of the feedback and its influence on behavior change. Six months after completing and receiving HRA personalized feedback, participants in two separate Indiana organizations answered survey questions about the HRA value, motivational influence, and ability to prompt behavior change...
January 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28130434/selective-progesterone-receptor-modulator-sprm-ulipristal-acetate-upa-and-its-effects-on-the-human-endometrium
#11
L H R Whitaker, A A Murray, R Matthews, G Shaw, A R W Williams, P T K Saunders, H O D Critchley
STUDY QUESTION: What is the impact of administration of the selective progesterone receptor modulator (SPRM), ulipristal acetate (UPA) on the endometrium of women with fibroids? SUMMARY ANSWER: UPA administration altered expression of sex-steroid receptors and progesterone-regulated genes and was associated with low levels of glandular and stromal cell proliferation. WHAT IS KNOWN ALREADY: Administration of all SPRM class members results in PAEC (progesterone receptor modulator associated endometrial changes)...
January 26, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28126455/a-coaching-by-telephone-intervention-for-veterans-and-care-team-engagement-activate-a-study-protocol-for-a-hybrid-type-i-effectiveness-implementation-randomized-controlled-trial
#12
Eugene Z Oddone, Laura J Damschroder, Jennifer Gierisch, Maren Olsen, Angela Fagerlin, Linda Sanders, Jordan Sparks, Marsha Turner, Carrie May, Felicia McCant, David Curry, Courtney White-Clark, Karen Juntilla
INTRODUCTION: A large proportion of deaths and many illnesses can be attributed to three modifiable risk factors: tobacco use, overweight/obesity, and physical inactivity. Health risk assessments (HRAs) are widely available online but have not been consistently used in healthcare systems to activate patients to participate in prevention programs aimed at improving lifestyle behaviors. OBJECTIVES: The goal of this study is to test whether adding telephone-based coaching to use of a comprehensive HRA increases at-risk patients' activation and enrollment into a prevention program compared to HRA use alone...
April 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28100480/detection-of-posterior-vortex-veins-in-eyes-with-pathologic-myopia-by-ultra-widefield-indocyanine-green-angiography
#13
Muka Moriyama, Kejia Cao, Satoko Ogata, Kyoko Ohno-Matsui
AIMS: To analyse the characteristics of posterior vortex veins detected in highly myopic eyes by wide-field indocyanine green angiography (ICGA). METHODS: One hundred and fifty-eight consecutive patients (302 eyes) with high myopia (myopic refractive error >8.0 dioptres (D) or axial length ≥26.5 mm) were studied. Wide-field ICGA was performed with the Spectralis HRA module. RESULTS: Posterior vortex veins were found in 80 eyes (26%)...
January 18, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28091842/squamous-cell-dysplasia-in-the-proximal-rectum-of-three-patients-treated-for-ulcerative-colitis-on-immunomodulators
#14
James G Connolly, Stephen E Goldstone
BACKGROUND: Anal canal high-grade squamous intraepithelial lesion (HSIL) is the precursor to anal cancer. Immunocompromised patients are at increased risk and disease is usually within 3 cm from the anal verge. High-resolution anoscopy (HRA) with an 8-cm anoscope is used to identify and guide cautery treatment of HSIL. PURPOSE: We report three patients with a long-term history of ulcerative colitis (UC) treated with systemic immunomodulators who developed proximally located rectal HSIL...
January 13, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28069281/-effect-of-donor-graft-characteristics-on-clinical-outcomes-in-descemet-stripping-automated-endothelial-keratoplasty-dsaek
#15
G Ho Wang Yin, M Sampo, S Soare, L Hoffart
INTRODUCTION: The purpose of our study was to evaluate the progression of lamellar corneal grafts after endothelial keratoplasty by Descemet stripping automated endothelial keratoplasty (DSAEK) and the effect of their characteristics on the clinical and functional results. MATERIALS AND METHODS: This was a prospective study in which 74 patients who had undergone endothelial keratoplasty by DSAEK were included. The corneal grafts were obtained from a French tissue bank and were delivered in a preservation medium containing a deturgescent agent (Corneajet(®) or Stemalpha 3(®))...
January 6, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28039281/association-of-rate-dependent-conduction-block-between-eccentric-coronary-sinus-to-left-atrial-connections-with-inducible-atrial-fibrillation-and-flutter
#16
Dong Huang, Joseph E Marine, Jing-Bo Li, Tarek Zghaib, Esra Gucuk Ipek, Sunil Sinha, David D Spragg, Hiroshi Ashikaga, Ronald D Berger, Hugh Calkins, Saman Nazarian
BACKGROUND: We sought to describe the prevalence and variability of coronary sinus (CS) and left atrial (LA) myocardium connections, their susceptibility to rate-dependent conduction block, and association with atrial fibrillation (AF) and flutter induction. METHODS AND RESULTS: The study cohort included 30 consecutive AF patients (age 63.3±10.5 years, 63% male). Multipolar catheters were positioned in the CS, high right atrium (HRA), and LA parallel to and near the CS...
January 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28029495/an-algorithm-of-image-heterogeneity-with-contrast-enhanced-ultrasound-in-differential-diagnosis-of-solid-thyroid-nodules
#17
Lifang Jin, Changsong Xu, Xueqian Xie, Fan Li, Xiuhong Lv, Lianfang Du
Enhancement heterogeneity on contrast-enhanced ultrasonography (CEUS) is used to differentiate between benign and malignant thyroid nodules. In this study, we used an algorithm to quantify enhancement heterogeneity of solid thyroid nodules on CEUS. The heterogeneity value (HV) is calculated as standard deviation/mean intensity × 100 (using Adobe Photoshop). The heterogeneity ratio (HR) is calculated as the ratio of the HV of the nodule to that of the surrounding parenchyma. Three phases-ascending, peak and descending phases-were studied...
October 28, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28026999/the-association-of-sleep-duration-and-morbid-obesity-in-a-working-population-the-baptist-health-south-florida-employee-study
#18
Muhammad Aziz, Chukwuemeka U Osondu, Adnan Younus, Rehan Malik, Maribeth Rouseff, Sankalp Das, Henry Guzman, Wasim Maziak, Salim Virani, Theodore Feldman, Arthur S Agatston, Emir Veledar, Ehimen C Aneni, Khurram Nasir
BACKGROUND: The current study aimed to determine the relationship between self-reported sleep duration and morbid obesity in an employee population. METHODS: Baptist Health South Florida conducts an annual Health Risk Assessment (HRA) for its employees. Data for this cross-sectional study was collected via this HRA in 2014, and included information on self-reported sleep duration, height and weight for body mass index (BMI), and other biometric measures. Average sleep duration was categorized as short sleep (<6 hr), optimal sleep (6-7...
December 27, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27965301/high-rates-of-anal-high-grade-squamous-intraepithelial-lesions-in-hiv-infected-women-who-do-not-meet-screening-guidelines
#19
Michael Gaisa, Fanny Ita-Nagy, Keith Sigel, Yotam Arens, Mary Ann Hennessy, Gabriela Rodriguez-Caprio, Michael Mullen, Judith A Aberg, Michelle Cespedes
BACKGROUND: Human immunodeficiency virus (HIV)-infected women have a higher burden of anal high-grade squamous intraepithelial lesions (HSIL) and anal cancer (AC) compared with HIV-uninfected women. Guidelines for AC screening in this population are heterogeneous. Here we report outcomes and risk factors for anal HSIL following implementation of universal AC screening offered to all HIV-infected women. METHODS: Data from women who underwent AC screening with anal cytology from April 2009 to July 2014 were analyzed...
February 1, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27958616/the-effect-of-atrial-pacing-site-on-electrophysiological-properties-of-the-atrioventricular-junction-and-induction-of-atrioventricular-nodal-reentry-in-patients-with-typical-atrioventricular-nodal-reentrant-tachycardia
#20
Radosław Marek Kiedrowicz, Jarosław Kaźmierczak, Maciej Wielusiński
BACKGROUND: Clinical studies in humans have shown the site of atrial stimulation to influence atrioventricular (AV) conduction times and refractory periods, the demonstration of dual atrioventricular nodal (AVN) pathways and induction of AVN reentry. These studies often found conflicting results. Moreover among enrolled patients the minority of them were found to have atrioventricular nodal reentrant tachycardia (AVNRT). The purpose of this study was to investigate the effect of the right and left atrial pacing on electrophysiological properties of the AV junction in the typical AVNRT population...
December 13, 2016: Kardiologia Polska
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