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https://www.readbyqxmd.com/read/28100480/detection-of-posterior-vortex-veins-in-eyes-with-pathologic-myopia-by-ultra-widefield-indocyanine-green-angiography
#1
Muka Moriyama, Kejia Cao, Satoko Ogata, Kyoko Ohno-Matsui
AIMS: To analyse the characteristics of posterior vortex veins detected in highly myopic eyes by wide-field indocyanine green angiography (ICGA). METHODS: One hundred and fifty-eight consecutive patients (302 eyes) with high myopia (myopic refractive error >8.0 dioptres (D) or axial length ≥26.5 mm) were studied. Wide-field ICGA was performed with the Spectralis HRA module. RESULTS: Posterior vortex veins were found in 80 eyes (26%)...
January 18, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28091842/squamous-cell-dysplasia-in-the-proximal-rectum-of-three-patients-treated-for-ulcerative-colitis-on-immunomodulators
#2
James G Connolly, Stephen E Goldstone
BACKGROUND: Anal canal high-grade squamous intraepithelial lesion (HSIL) is the precursor to anal cancer. Immunocompromised patients are at increased risk and disease is usually within 3 cm from the anal verge. High-resolution anoscopy (HRA) with an 8-cm anoscope is used to identify and guide cautery treatment of HSIL. PURPOSE: We report three patients with a long-term history of ulcerative colitis (UC) treated with systemic immunomodulators who developed proximally located rectal HSIL...
January 13, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28069281/-effect-of-donor-graft-characteristics-on-clinical-outcomes-in-descemet-stripping-automated-endothelial-keratoplasty-dsaek
#3
G Ho Wang Yin, M Sampo, S Soare, L Hoffart
INTRODUCTION: The purpose of our study was to evaluate the progression of lamellar corneal grafts after endothelial keratoplasty by Descemet stripping automated endothelial keratoplasty (DSAEK) and the effect of their characteristics on the clinical and functional results. MATERIALS AND METHODS: This was a prospective study in which 74 patients who had undergone endothelial keratoplasty by DSAEK were included. The corneal grafts were obtained from a French tissue bank and were delivered in a preservation medium containing a deturgescent agent (Corneajet(®) or Stemalpha 3(®))...
January 6, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28039281/association-of-rate-dependent-conduction-block-between-eccentric-coronary-sinus-to-left-atrial-connections-with-inducible-atrial-fibrillation-and-flutter
#4
Dong Huang, Joseph E Marine, Jing-Bo Li, Tarek Zghaib, Esra Gucuk Ipek, Sunil Sinha, David D Spragg, Hiroshi Ashikaga, Ronald D Berger, Hugh Calkins, Saman Nazarian
BACKGROUND: We sought to describe the prevalence and variability of coronary sinus (CS) and left atrial (LA) myocardium connections, their susceptibility to rate-dependent conduction block, and association with atrial fibrillation (AF) and flutter induction. METHODS AND RESULTS: The study cohort included 30 consecutive AF patients (age 63.3±10.5 years, 63% male). Multipolar catheters were positioned in the CS, high right atrium (HRA), and LA parallel to and near the CS...
January 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28029495/an-algorithm-of-image-heterogeneity-with-contrast-enhanced-ultrasound-in-differential-diagnosis-of-solid-thyroid-nodules
#5
Lifang Jin, Changsong Xu, Xueqian Xie, Fan Li, Xiuhong Lv, Lianfang Du
Enhancement heterogeneity on contrast-enhanced ultrasonography (CEUS) is used to differentiate between benign and malignant thyroid nodules. In this study, we used an algorithm to quantify enhancement heterogeneity of solid thyroid nodules on CEUS. The heterogeneity value (HV) is calculated as standard deviation/mean intensity × 100 (using Adobe Photoshop). The heterogeneity ratio (HR) is calculated as the ratio of the HV of the nodule to that of the surrounding parenchyma. Three phases-ascending, peak and descending phases-were studied...
October 28, 2016: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28026999/the-association-of-sleep-duration-and-morbid-obesity-in-a-working-population-the-baptist-health-south-florida-employee-study
#6
Muhammad Aziz, Chukwuemeka U Osondu, Adnan Younus, Rehan Malik, Maribeth Rouseff, Sankalp Das, Henry Guzman, Wasim Maziak, Salim Virani, Theodore Feldman, Arthur S Agatston, Emir Veledar, Ehimen C Aneni, Khurram Nasir
BACKGROUND: The current study aimed to determine the relationship between self-reported sleep duration and morbid obesity in an employee population. METHODS: Baptist Health South Florida conducts an annual Health Risk Assessment (HRA) for its employees. Data for this cross-sectional study was collected via this HRA in 2014, and included information on self-reported sleep duration, height and weight for body mass index (BMI), and other biometric measures. Average sleep duration was categorized as short sleep (<6 hr), optimal sleep (6-7...
December 27, 2016: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/27965301/high-rates-of-anal-high-grade-squamous-intraepithelial-lesions-in-hiv-infected-women-who-do-not-meet-screening-guidelines
#7
Michael Gaisa, Fanny Ita-Nagy, Keith Sigel, Yotam Arens, Mary Ann Hennessy, Gabriela Rodriguez-Caprio, Michael Mullen, Judith A Aberg, Michelle Cespedes
BACKGROUND: Human immunodeficiency virus (HIV)-infected women have a higher burden of anal high-grade squamous intraepithelial lesions (HSIL) and anal cancer (AC) compared with HIV-uninfected women. Guidelines for AC screening in this population are heterogeneous. Here we report outcomes and risk factors for anal HSIL following implementation of universal AC screening offered to all HIV-infected women. METHODS: Data from women who underwent AC screening with anal cytology from April 2009 to July 2014 were analyzed...
February 1, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/27958616/the-effect-of-atrial-pacing-site-on-electrophysiological-properties-of-the-atrioventricular-junction-and-induction-of-atrioventricular-nodal-reentry-in-patients-with-typical-atrioventricular-nodal-reentrant-tachycardia
#8
Radosław Marek Kiedrowicz, Jarosław Kaźmierczak, Maciej Wielusiński
BACKGROUND: Clinical studies in humans have shown the site of atrial stimulation to influence atrioventricular (AV) conduction times and refractory periods, the demonstration of dual atrioventricular nodal (AVN) pathways and induction of AVN reentry. These studies often found conflicting results. Moreover among enrolled patients the minority of them were found to have atrioventricular nodal reentrant tachycardia (AVNRT). The purpose of this study was to investigate the effect of the right and left atrial pacing on electrophysiological properties of the AV junction in the typical AVNRT population...
December 13, 2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27915994/is-educational-attainment-associated-with-increased-risk-of-mortality-in-people-with-dementia-a-population-based-study
#9
Israel Contador, Yaakov Stern, Félix Bermejo-Pareja, Álvaro Sánchez-Ferro, Julián Benito-León
OBJECTIVE: The association between higher education and increased mortality in Alzheimer's disease (AD) is controversial. Further it is unknown whether education predicts survival in all dementia subtypes. We assessed mortality rates and death causes of persons with dementia compared to participants without dementia. METHODS: Participants derive from the Neurological Disorders in Central Spain, a prospective population-based cohort study of older adults. We compared 269 persons with dementia to 2944 participants without dementia...
December 1, 2016: Current Alzheimer Research
https://www.readbyqxmd.com/read/27888094/nano-analyses-of-wear-particles-from-metal-on-metal-and-non-metal-on-metal-dual-modular-neck-hip-arthroplasty
#10
Zhidao Xia, Benjamin F Ricciardi, Zhao Liu, Christopher von Ruhland, Mike Ward, Alex Lord, Louise Hughes, Steven R Goldring, Edward Purdue, David Murray, Giorgio Perino
Increased failure rates due to metallic wear particle-associated adverse local tissue reactions (ALTR) is a significant clinical problem in resurfacing and total hip arthroplasty. Retrieved periprosthetic tissue of 53 cases with corrosion/conventional metallic wear particles from 285 revision operations for ALTR was selected for nano-analyses. Three major classes of hip implants associated with ALTR, metal-on-metal hip resurfacing arthroplasty (MoM HRA) and large head total hip replacement (MoM LHTHA) and non-metal-on-metal dual modular neck total hip replacement (Non-MoM DMNTHA) were included...
November 22, 2016: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/27883260/the-use-of-incretin-agents-and-risk-of-acute-and-chronic-pancreatitis-a-population-based-cohort-study
#11
Lotte M Knapen, Roy G P J de Jong, Johanna H M Driessen, Yolande C Keulemans, Nielka P van Erp, Marie L De Bruin, Hubert G M Leufkens, Sander Croes, Frank de Vries
BACKGROUND: Incretin-based therapies (Dipeptidyl Peptidase 4 inhibitors and Glucagon-Like Peptide-1 Receptor Agonists) are effective new agents for the treatment of Type 2 Diabetes Mellitus (T2DM). While incretin-based therapies have been associated with pancreatitis, evidence is conflicting for acute pancreatitis and lacks for chronic pancreatitis. OBJECTIVE: To determine the association between the use of incretin agents and the risk of any, acute and chronic pancreatitis...
November 24, 2016: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/27872117/protocol-for-a-multicentre-randomised-feasibility-trial-evaluating-early-surgery-alone-in-low-rectal-cancer-sailor
#12
Dean A Harris, Kymberley Thorne, Hayley Hutchings, Saiful Islam, Gail Holland, Olivia Hatcher, Sarah Gwynne, Ian Jenkins, Peter Coyne, Michael Duff, Melanie Feldman, Des C Winter, Simon Gollins, Phil Quirke, Nick West, Gina Brown, Deborah Fitzsimmons, Alan Brown, John Beynon
INTRODUCTION: There are 11 500 rectal cancers diagnosed annually in the UK. Although surgery remains the primary treatment, there is evidence that preoperative radiotherapy (RT) improves local recurrence rates. High-quality surgery in rectal cancer is equally important in minimising local recurrence. Advances in MRI-guided prediction of resection margin status and improvements in abdominoperineal excision of the rectum (APER) technique supports a reassessment of the contribution of preoperative RT...
November 21, 2016: BMJ Open
https://www.readbyqxmd.com/read/27852400/-diagnostic-performance-of-laser-retinal-imaging-in-the-epiretinal-membrane
#13
Y J Huo, L L Yang, W B Wei
Objective: To determine the diagnostic performance of confocal scanning laser ophthalmoscope (cSLO)-based retinal imaging in the epiretinal membrane (ERM) patients. Methods: Prospective case series study. Twenty-six patients (32 eyes) with ERM determined by spectral domain optical coherence tomography (SD-OCT) were recruited from June 2015 to October 2015 in the Beijing Tongren Eye Center. All subjects underwent retinal imaging using the cSLO-based Heidelberg MultiColor (Spectralis HRA-2; Heidelberg Engineering) technology and the traditional color fundus camera...
November 11, 2016: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27845887/a-review-of-heavy-metals-in-indoor-dust-and-its-human-health-risk-implications
#14
Sock Yin Tan, Sarva Mangala Praveena, Emilia Zainal Abidin, Manraj Singh Cheema
Indoor dust acts as a media for heavy metal deposition. Past studies have shown that heavy metal concentration in indoor dust is affected by local human activities and atmospheric transport can have harmful effects on human health. Additionally, children are more sensitive to heavy metals due to their hand-to-mouth behaviour and rapid body development. However, limited information on health risks were found in past dust studies as these studies aimed to identify heavy metal concentrations and sources of indoor dust...
December 1, 2016: Reviews on Environmental Health
https://www.readbyqxmd.com/read/27830330/risk-factors-of-nonadherence-to-colonoscopy-surveillance-after-polypectomy-and-its-impact-on-clinical-outcomes-a-kasid-multicenter-study
#15
Chung Hyun Tae, Chang Mo Moon, Seong-Eun Kim, Sung-Ae Jung, Chang Soo Eun, Jae Jun Park, Geom Seog Seo, Jae Myung Cha, Sung Chul Park, Jaeyoung Chun, Hyun Jung Lee, Yunho Jung, Jin Oh Kim, Young-Eun Joo, Dong Il Park
BACKGROUND: An optimal surveillance program is important to prevent advanced colorectal neoplasm. In this context, we have evaluated the cumulative risk of high-risk adenoma (HRA) or colorectal cancer (CRC) according to surveillance interval time after polypectomy. In addition, we assessed risk factors for late surveillance to determine whether late surveillance can impact the risk of subsequent advanced colorectal neoplasm. METHODS: This was a multicenter retrospective cohort study involving 3562 subjects who had undergone removal of at least one adenoma at the index colonoscopy and who subsequently underwent a surveillance colonoscopy...
November 9, 2016: Journal of Gastroenterology
https://www.readbyqxmd.com/read/27829336/effectiveness-of-a-standardized-and-specific-follow-up-in-memory-centers-in-patients-with-alzheimer-s-disease
#16
Laure Rouch, Philippe Cestac, Charlène Cool, Catherine Helmer, Jean-François Dartigues, Claudine Berr, Olivier Rouaud, Bruno Vellas, Sandrine Andrieu
OBJECTIVES: To compare the 4-year survival, institutionalization, cognitive and functional decline of Alzheimer's patients with specific follow-up in memory centers versus usual care. DESIGN: Four year longitudinal follow-up. SETTINGS: The French Network of memory centers in Alzheimer's disease (REAL-FR study) and The French population-based study (3C study). PARTICIPANTS: 728 patients aged ≥ 65, living at home, meeting criteria for probable Alzheimer's disease and having Mini Mental State Examination (MMSE) scores between 10 and 26 at baseline were included...
November 8, 2016: Current Alzheimer Research
https://www.readbyqxmd.com/read/27806411/anal-chromoendoscopy-using-gastroenterological-video-endoscopes-a-new-method-to-perform-high-resolution-anoscopy-for-diagnosing-intraepithelial-neoplasia-and-anal%C3%A2-carcinoma-in-hiv-infected-patients
#17
Mark Oette, Ulrike Wieland, Marko Schünemann, Johannes Haes, Stefan Reuter, Björn Erik Ole Jensen, Abdurrahman Sagir, Herbert Pfister, Dieter Häussinger
Introduction Anal carcinoma represents an increasing problem in HIV-infected patients. Anal intraepithelial neoplasia (AIN), the precursor lesion, is currently diagnosed by high-resolution anoscopy (HRA) using optical magnification derived from gynecological colposcopy. This prospective study evaluates anal chromoendoscopy (ACE) using standard gastroenterological video-endoscopes in diagnosing AIN. Methods After clinical examination, proctoscopy and surface staining with acetic acid followed by Lugol's solution, ACE was performed with a mucosectomy cap on the tip of the endoscope...
January 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/27780174/clinical-spectrum-of-macular-foveal-capillaries-evaluated-with-optical-coherence-tomography-angiography
#18
Maria V Cicinelli, Adriano Carnevali, Alessandro Rabiolo, Lea Querques, Ilaria Zucchiatti, Vincenzo Scorcia, Francesco Bandello, Giuseppe Querques
PURPOSE: To describe macular-foveal capillaries (MFC) by means of optical coherence tomography angiography and to identify the clinical spectrum of this angiographic feature. METHODS: Patients with MFC presenting at the Medical Retina & Imaging Unit of the Department of Ophthalmology, University Vita-Salute San Raffaele in Milan were recruited. Patients underwent a complete ophthalmologic examination that included slit-lamp examination, fundus examination, measurement of best-corrected visual acuity, fundus autofluorescence, and spectral-domain optical coherence tomography (Spectralis HRA + OCT; Heidelberg Engineering, Heidelberg, Germany)...
July 12, 2016: Retina
https://www.readbyqxmd.com/read/27765999/hydrophobic-resorufamine-derivatives-potent-and-selective-red-fluorescent-probes-of-the-endoplasmic-reticulum-of-mammalian-cells
#19
Sahishna Phaniraj, Zhe Gao, Digamber Rane, Blake R Peterson
The endoplasmic reticulum (ER) of eukaryotic cells plays critical roles in the processing of secreted and transmembrane proteins. Defects in these functions are associated with a wide range of pathologies. To image this organelle, cells are often treated with fluorescent ER-Tracker dyes. Although these compounds are selective, existing red fluorescent probes of the ER are costly glibenclamide derivatives that inhibit ER-associated sulphonylurea receptors. To provide simpler and more cost-effective red fluorescent probes of the ER, we synthesized amino analogues of the fluorophore resorufin...
December 2016: Dyes and Pigments: An International Journal
https://www.readbyqxmd.com/read/27759474/poor-10-year-survivorship-of-hip-resurfacing-arthroplasty
#20
Matti Seppänen, Mikko Karvonen, Petri Virolainen, Ville Remes, Pekka Pulkkinen, Antti Eskelinen, Antti Liukas, Keijo T Mäkelä
Background and purpose - In a previous registry report, short-term implant survival of hip resurfacing arthroplasty (HRA) in Finland was found to be comparable to that of total hip arthroplasty (THA). Since then, it has become evident that adverse reactions to metal debris (ARMDs) may also be associated with HRA, not only with large-diameter head metal-on-metal THA. The aim of the study was to assess medium- to long-term survivorship of HRA based on the Finnish Arthroplasty Register (FAR). Patients and methods - 5,068 HRAs performed during the period 2001-2013 in Finland were included...
December 2016: Acta Orthopaedica
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