keyword
MENU ▼
Read by QxMD icon Read
search

Apes

keyword
https://www.readbyqxmd.com/read/28448977/is-human-oxoguanine-glycosylase-1-genetic-variant-successful-even-on-oral-squamous-cell-carcinoma
#1
Levent Aydemir, Elif Sinem Bireller, Hakan Avci, Zeynep Boy Metin, Kemal Deger, Meral Unur, Bedia Cakmakoglu
BACKGROUND: Oral squamous cell carcinoma (OSCC) is one of the most widespread cancer types that arise from different sites of oral cavity and has a 5-year survival rate. This study is aimed at investigating the human oxoguanine glycosylase 1 (hOGG1)-Ser326Cys and APE-Asp148Glu polymorphisms of DNA repair genes in OSCC. MATERIALS AND METHODS: We investigated the hOGG1-Ser326Cys and APE-Asp148Glu polymorphisms of DNA repair genes in the oral cavity. Genotyping was conducted using polymerase chain reaction-restriction fragment length polymorphism analysis based on 132 patients who were diagnosed as having OSCC and 160 healthy subjects...
April 28, 2017: Pathobiology: Journal of Immunopathology, Molecular and Cellular Biology
https://www.readbyqxmd.com/read/28447741/effect-of-isosecotanapartholide-isolated-from-artemisia%C3%A2-princeps-pampanini-on-il%C3%A2-33-production-and-stat%C3%A2-1-activation-in-hacat-keratinocytes
#2
Chang Taek Oh, Yu-Jin Jang, Tae-Rin Kwon, Songi Im, Soon Re Kim, Joon Seok, Gun-Yong Kim, Young-Heui Kim, Seog Kyun Mun, Beom Joon Kim
The present study aimed to investigate the anti‑inflammatory effect and mechanism of action of isosecotanapartholide (ISTP), isolated from Artemisia princeps Pampanini extract (APE). The effects of ISTP and APE on the proliferation of human keratinocytes following stimulation by tumor necrosis factor‑α/interferon‑γ were assessed. ISTP and APE downregulated the expression levels of signal transducer and activator of transcription‑1 (STAT‑1), and reduced interleukin‑33 (IL‑33) production. ISTP and APE inhibited the mRNA expression levels of thymus and activation‑regulated chemokine (TARC/CCL17) in a dose‑dependent manner...
March 9, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28446233/no-impact-of-strongylid-infections-on-the-detection-of-plasmodium-spp-in-faeces-of-western-lowland-gorillas-and-eastern-chimpanzees
#3
Mwanahamisi I Mapua, Barbora Pafčo, Jade Burgunder, Ilona Profousová-Pšenková, Angelique Todd, Chie Hashimoto, Moneeb A Qablan, David Modrý, Klára J Petrželková
BACKGROUND: Although a high genetic diversity of Plasmodium spp. circulating in great apes has been revealed recently due to non-invasive methods enabling detection in faecal samples, little is known about the actual mechanisms underlying the presence of Plasmodium DNA in faeces. Great apes are commonly infected by strongylid nematodes, including hookworms, which cause intestinal bleeding. The impact of strongylid infections on the detection of Plasmodium DNA in faeces was assessed in wild, western, lowland gorillas from Dzanga Sangha Protected Areas, Central African Republic and eastern chimpanzees from Kalinzu Forest Reserve, Uganda...
April 26, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28441555/rapid-evolution-of-the-cerebellum-in-humans-and-other-great-apes
#4
Robert A Barton, Chris Venditti
No abstract text is available yet for this article.
April 24, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28437739/experimental-study-on-evaluation-and-optimization-of-tilt-angle-of-parallel-plate-electrodes-using-electrocoagulation-device-for-oily-water-demulsification
#5
Yang Liu, Wen-Ming Jiang, Jie Yang, Yu-Xing Li, Ming-Can Chen, Jian-Na Li
Tilt angle of parallel-plate electrodes (APE) is very important as it improves the economy of diffusion controlled Electrocoagulation (EC) processes. This study aimed to evaluate and optimize APE of a self-made EC device including integrally rotary electrodes, at a fixed current density of 120 Am(-2). The APEs investigated in this study were selected at 0°, 30°, 45°, 60°, 90°, and a special value (α(d)) which was defined as a special orientation of electrode when the upper end of anode and the lower end of cathode is in a line vertical to the bottom of reactor...
April 12, 2017: Chemosphere
https://www.readbyqxmd.com/read/28434534/comparative-analysis-of-trabecular-bone-structure-and-orientation-in-south-african-hominin-tali
#6
Anne Su, Kristian J Carlson
Tali of several hominin taxa are preserved in the fossil record and studies of the external morphology of these often show a mosaic of human-like and ape-like features. This has contributed to a growing recognition of variability characterizing locomotor kinematics of Australopithecus. In contrast, locomotor kinematics of another Plio-Pleistocene hominin, Paranthropus, are substantially less well-documented, in part, because of the paucity of postcranial fossils securely attributed to the genus. Since the talus transmits locomotor-based loads through the ankle and its internal structure is hypothesized to reflect accommodation to such loads, it is a cornerstone structure for reconstructing locomotor kinematics...
May 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28433937/perturbation-effect-of-reduced-graphene-oxide-quantum-dots-rgoqds-on-aryl-hydrocarbon-receptor-ahr-pathway-in-zebrafish
#7
Jing-Hui Zhang, Tai Sun, Aping Niu, Yu-Mei Tang, Shun Deng, Wei Luo, Qun Xu, Dapeng Wei, De-Sheng Pei
Graphene quantum dots (GQDs) has been widely used in enormous fields, however, the inherent molecular mechanism of GQDs for potential risks in biological system is still elusive to date. In this study, the outstanding reduced graphene quantum dots (rGOQDs) with the QY as high as 24.62% were successfully synthesized by the improved Hummers method and DMF hydrothermal treatment approach. The rGOQDs were N-doped photoluminescent nanomaterials with functional groups on the surface. The fluorescent bio-imaging was performed by exposing zebrafish in different concentrations of the as-prepared rGOQDs, and the distribution of rGOQDs was successfully observed...
April 15, 2017: Biomaterials
https://www.readbyqxmd.com/read/28432829/trabecular-mapping-leveraging-geometric-morphometrics-for-analyses-of-trabecular-structure
#8
Adam D Sylvester, Claire E Terhune
OBJECTIVES: Trabecular microstructure of limb bone epiphyses has been used to elucidate the relationship between skeletal form and behavior among mammals. Such studies have often relied on the analysis of a single volume of interest (VOI). Here we present a method for evaluating variation in bone microstructure across articular surfaces by leveraging sliding semilandmarks. METHODS: Two samples were used to demonstrate the proposed methodology and test the hypothesis that microstructural variables are homogeneously distributed: tali from two ape genera (Pan and Pongo, n = 9) and modern human distal femora (n = 10)...
April 22, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28431873/a-novel-clinical-index-for-the-assessment-of-rvd-in-acute-pulmonary-embolism-blood-pressure-index
#9
Hale Ates, Ihsan Ates, Harun Kundi, Mehmet Fettah Arikan, Fatma Meric Yilmaz
BACKGROUND: This study aims to investigate the role of the blood pressure index (BPI), which is a new index that we developed, in detection of right ventricular dysfunction (RVD) in acute pulmonary embolism (APE). METHODS: A total of 539 patients, (253 males and 286 females), diagnosed with APE using computer tomography pulmonary angiography were included in the study. The BPI was obtained by dividing systolic blood pressure (SBP) by diastolic blood pressure (DBP)...
April 12, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28431000/left-brain-asymmetry-of-the-planum-temporale-in-a-nonhominid-primate-redefining-the-origin-of-brain-specialization-for-language
#10
Damien Marie, Muriel Roth, Romain Lacoste, Bruno Nazarian, Alice Bertello, Jean-Luc Anton, William D Hopkins, Konstantina Margiotoudi, Scott A Love, Adrien Meguerditchian
The planum temporale (PT) is a critical region of the language functional network in the human brain showing a striking size asymmetry toward the left hemisphere. Historically considered as a structural landmark of the left-brain specialization for language, a similar anatomical bias has been described in great apes but never in monkeys-indicating that this brain landmark might be unique to Hominidae evolution. In the present in vivo magnetic resonance imaging study, we show clearly for the first time in a nonhominid primate species, an Old World monkey, a left size predominance of the PT among 96 olive baboons (Papio anubis), using manual delineation of this region in each individual hemisphere...
April 19, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28418109/sagittal-crest-formation-in-great-apes-and-gibbons
#11
Katharine L Balolia, Christophe Soligo, Bernard Wood
The frequency of sagittal crest expression and patterns of sagittal crest growth and development have been documented in hominoids, including some extinct hominin taxa, and the more frequent expression of the sagittal crest in males has been traditionally linked with the need for larger-bodied individuals to have enough attachment area for the temporalis muscle. In the present study, we investigate sagittal cresting in a dentally mature sample of four hominoid taxa (Pan troglodytes schweinfurthii, Gorilla gorilla gorilla, Pongo pygmaeus pygmaeus and Hylobates lar)...
April 18, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28407328/distinctiveness-enhances-long-term-event-memory-in-non-human-primates-irrespective-of-reinforcement
#12
Amy Lewis, Josep Call, Dorthe Berntsen
Non-human primates are capable of recalling events that occurred as long as 3 years ago, and are able to distinguish between similar events; akin to human memory. In humans, distinctiveness enhances memory for events, however, it is unknown whether the same occurs in non-human primates. As such, we tested three great ape species on their ability to remember an event that varied in distinctiveness. Across three experiments, apes witnessed a baiting event in which one of three identical containers was baited with food...
April 13, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28407267/orangutans-enamel-defects-and-developmental-health-a-comparison-of-borneo-and-sumatra
#13
Mark F Skinner, Matthew M Skinner
Orangutans (Pongo sp.) show among the highest occurrence of three types of developmental enamel defect. Two are attributed to nutritional factors that reduce bone growth in the infant's face early in development. Their timing and prevalence indicate that Sumatra provides a better habitat than does Borneo. The third type, repetitive linear enamel hypoplasia (rLEH) is very common but its etiology is not understood. Our objective is to draw attention to this enigmatic, episodic stressor in the lives of orangutans...
April 13, 2017: American Journal of Primatology
https://www.readbyqxmd.com/read/28406569/ischial-form-as-an-indicator-of-bipedal-kinematics-in-early-hominins-a-test-using-extant-anthropoids
#14
Kristi L Lewton, Jeremiah E Scott
Human ischia contrast with those of great apes in being craniocaudally short and dorsally projecting. This configuration is thought to facilitate greater hip extension in humans during bipedal locomotion. This link has been used to infer kinematics in early hominins, but the consequences of variation in ischial configuration for gait remain uncertain. Kinematic data for a limited sample of extant nonhuman primates demonstrate that there is variation in hip extension in these taxa during bipedal behaviors-specifically, Hylobates and Ateles are capable of greater extension than Pan and Macaca...
May 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28406563/evolution-of-the-human-pelvis
#15
Karen R Rosenberg, Jeremy M DeSilva
No bone in the human postcranial skeleton differs more dramatically from its match in an ape skeleton than the pelvis. Humans have evolved a specialized pelvis, well-adapted for the rigors of bipedal locomotion. Precisely how this happened has been the subject of great interest and contention in the paleoanthropological literature. In part, this is because of the fragility of the pelvis and its resulting rarity in the human fossil record. However, new discoveries from Miocene hominoids and Plio-Pleistocene hominins have reenergized debates about human pelvic evolution and shed new light on the competing roles of bipedal locomotion and obstetrics in shaping pelvic anatomy...
May 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28406561/lower-ilium-evolution-in-apes-and-hominins
#16
Ashley S Hammond, Sergio Almécija
Elucidating the pelvic morphology of the Pan-Homo last common ancestor (LCA) is crucial for understanding ape and human evolution. The pelvis of Ardipithecus ramidus has been the basis of controversial interpretations of the LCA pelvis. In particular, it was proposed that the lower ilium became elongate independently in the orangutan and chimpanzee clades, making these taxa poor analogues for the pelvis of the LCA. This study examines the variation in relative lower ilium height between and within living and fossil hominoid species (and other anthropoids), and models its evolution using available fossil hominoids as calibration points...
May 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28406557/determinants-of-iliac-blade-orientation-in-anthropoid-primates
#17
Emily R Middleton, Zachariah J Winkler, Ashley S Hammond, J Michael Plavcan, Carol V Ward
Orientation of the iliac blades is a key feature that appears to distinguish extant apes from monkeys. Iliac morphology is hypothesized to reflect variation in thoracic shape that, in turn, reflects adaptations for shoulder and forearm function in anthropoids. Iliac orientation is traditionally measured relative to the acetabulum, whereas functional explanations pertain to its orientation relative to the cardinal anatomical planes. We investigated iliac orientation relative to a median plane using digital models of hipbones registered to landmark data from articulated pelves...
May 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28400988/the-%C3%AE-133p53-isoform-reduces-wtp53-induced-stimulation-of-dna-pol-%C3%AE-activity-in-the-presence-and-absence-of-d4t
#18
Kai Liu, Yunjin Zang, Xianghua Guo, Feili Wei, Jiming Yin, Lijun Pang, Dexi Chen
The mitochondrial toxicity of nucleoside reverse transcriptase inhibitors (NRTIs) is due to the inhibition of mitochondrial DNA (mtDNA) polymerase γ (pol γ). Previous studies have shown that wild type p53 (wtp53) can interact with pol γ and mtDNA to enhance mitochondrial DNA base excision repair (mtBER) activity and increase the accuracy of DNA synthesis. The N-terminal transactivation domain and central specific DNA-binding domain of p53 play critical roles in the stimulation of BER. In this study, we identified the possible roles of wtp53, Δ40p53 and Δ133p53 in regulating mtDNA pol γ activity in cells with d4T treatment...
April 2017: Aging and Disease
https://www.readbyqxmd.com/read/28400951/contribution-of-community-health-workers-to-improving-access-to-timely-and-appropriate-case-management-of-childhood-fever-in-mozambique
#19
Tanya Guenther, Salim Sadruddin, Karen Finnegan, Erica Wetzler, Fatima Ibo, Paulo Rapaz, Jeanne Koepsell, Ibad Ul Haque Khan, Agbessi Amouzou
BACKGROUND: Large scale evaluations in several settings have demonstrated that lay community health workers can be trained to provide quality case management of childhood illnesses. In 2010, Mozambique introduced the integrated community case management (iCCM) strategy to reach children in remote areas with care provided through Agentes Polivalentes Elementares (APEs). We assessed the contribution of the program to improved care-seeking and appropriate treatment of childhood febrile illness in Nampula Province...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28393042/utilization-of-eye-care-services-among-those-with-unilateral-visual-impairment-in-rural-south-india-andhra-pradesh-eye-disease-study-apeds
#20
Srinivas Marmamula, Pyda Giridhar, Rohit C Khanna
AIM: To report on the utilization of eye care services and its associated factors among those with unilateral visual impairment (VI) in a rural South Indian population. METHODS: A population based cross-sectional study was conducted in three districts (Adilabad, Mahbubnagar and West Godavari) in the state of Andhra Pradesh, India. A detailed interview and a comprehensive eye examination were conducted. Those with unilateral VI were asked questions about noticing any change in vision and on utilization of eye care services...
2017: International Journal of Ophthalmology
keyword
keyword
118651
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"