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https://www.readbyqxmd.com/read/29779289/-orthodontic-intrusion-of-the-first-and-second-mandibular-molars-with-a-vacuum-formed-removable-appliance-a-case-report
#1
Qing Liu, Xin-Qi Huang, Dan Jiang, Hao-Jun Chi, Ling-Jie Wang, Wen-Tian Sun, Jun Liu
This case report focused on a patient with supraeruption of the first and second mandibular molars as a result of loss of the first and second maxillary molars for a long time. We adopted a combination of a vacuum-formed removable appliance and elastics to intrude the first and second mandibular molars by using a continuous, light force to acquire sufficient restoration space for maxillary molars. Thus, the dental-implant treatment was successful, and a good and stable occlusal relationship was established.
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779281/-effects-of-tumor-necrosis-factor-%C3%AE-on-osteogenic-differentiation-and-notch-signaling-pathway-in-human-periodontal-ligament-stem-cells
#2
Yu Ma, Shu-Hui Li, Xin-Xin Ding, Pei-Ling Wu
OBJECTIVE: To evaluate the effects of tumor necrosis factor-α (TNF-α) on osteogenic differentiation and Notch signaling pathway of periodontal ligament stem cells (PDLSCs) and to investigate the regulatory role of Notch signaling pathway on the osteogenic differentiation of PDLSCs under the influence of TNF-α. METHODS: PDLSCs were obtained through enzyme digestion and tissue block method. The expression levels of stem cell surface markers CD105, CD90, CD146, CD45, and CD31 were detected by fluorescence activated cell sorter (FACS)...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779279/-effects-of-recasting-in-vacuum-with-argon-on-the-chemical-composition-of-ceramic-alloys
#3
Ying-Hui Wang, Fen-Fang Qiu, Wei-Qing Wu, Hui Cheng
OBJECTIVE: This study aimed to determine the effect of recasting in vacuum with argon on the chemical composition of cobalt-chromium (Co-Cr), commercially pure titanium (cpTi), palladium-based (Pd-based), and aurum-platinum (Au-
Pt) ceramic alloys. METHODS: Without adding new alloys, Co-Cr, cpTi, Pd-based, and Au-Pt ceramic alloys were recast one to three times under the condition of vacuum compressive casting with argon. Before recasting, four previously cast ceramic alloys were treated with the corresponding method...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779278/-time-lapse-between-endodontic-and-periodontal-treatments-of-combined-periodontal-endodontic-lesion-a-systematic-review
#4
Yue Jin, Bin Chen, Yan-Hong Ni, Fu-Hua Yan
OBJECTIVE: This study aims to evaluate the time lapse between the endodontic and periodontal treatments of the combined periodontal-endodontic lesion to guide the clinical treatment. METHODS: A systemic literature search was performed in articles published from 1980 to March 2017 using the electronic databases, including PubMed, EMbase, Cochrane, Web of Science, CNKI, CBM, and Wanfang Databases. RESULTS: After screening, two randomized controlled trials, two prospective case series studies, and eight case reports were ultimately included...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779274/-outcome-and-influential-factors-of-speech-therapy-delivered-to-cleft-patients-with-post-operative-velopharyngeal-competence
#5
Chun-Li Guo, Heng Yin, Jing-Tao Li, Cheng-Hao Li, Yang Li, Bing Shi, Qian Zheng
OBJECTIVE: To analyze the training technique, intervention timing, and other related factors involved in the speech therapy delivered to cleft patients with velopharyngeal competence after surgery. METHODS: A retrospective study was conducted on 32 patients who received phonology-articulation speech therapies during 2012 to 2013 in Dept. of Cleft Lip and Palate, West China Hospital of Stomatology, Sichuan University. All patients achieved normal speech one year after therapy...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779273/-effects-of-inhibitory-concentration-minocycline-on-the-proliferation-differentiation-and-mineralization-of-osteoblasts
#6
Hua-Ying Shao, Yi-Gong Zhang, Xue Yang, Qiong-Yue Zhang, Xiao-Hong Wu
OBJECTIVE: To study the effect of the inhibitory concentration minocycline on the proliferation, differentiation, and expression of Runt-related transcription factor 2 (Runx2), alkaline phosphatase (ALP) and osteopontin (OPN) mRNA of osteoblasts. METHODS: Primary osteoblasts were cultured in osteogenic induction medium containing 0, 0.1, 0.5, 1, 10 μg·mL⁻¹ minocycline. Cell counting kit-8 was used to observe cell proliferation. ALP activity assay, alizarin red S staining, and real-time quantitative polymerase chain reaction (PCR) were used to determine cell differentiation and mineralization...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779272/-effects-of-protein-kinase-c-and-motigen-activated-protein-kinase-kinase-extracellular-regulated-protein-kinases-signaling-pathway-on-mrna-level-of-inducible-nitric-oxide-synthase-in-tca8113-cells
#7
Xue-Feng Gao, Hai-Bin Jiao, Chang-Cheng Ye, Ying-Qun Liu
OBJECTIVE: To explore the regulatory mechanism of inducible nitric oxide synthase (NOS-2) expression related to proliferation of Tca8113 cells. METHODS: RNAi mediated by short hairpin RNAs was utilized to knock down NOS-2, protein kinase C (PKC)-α, PKC-β and PKC-δ. Griess Reagent played a significant role on the detection of NO product after NOS-2 silence. The cell proliferation was determined by CCK8 method. Quantitative real-time polymerase chain reaction (q-PCR) was recruited to check the mRNA level of NOS-2, PKC-α, PKC-β and PKC-δ after treated by a variety of ways...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779271/-local-injection-of-exogenous-nerve-growth-factor-improves-early-bone-maturation-of-implants
#8
Yang Yao, Yu Du, Xia Gu, Meng-Kai Guang, Bo Huang, Ping Gong
OBJECTIVE: To investigate the effects of nerve growth factor (NGF) in the osteogenic action of implants and the maturation and reconstruction changes in bone tissues in the early stage of osseointegration. METHODS: The mouse implant model was established by placing titanium in the femoral head of the mouse and locally injecting NGF in the implant zone. On 1, 2 and 4 weeks after operation, stain samples were collected from animals using hematoxylin-eosin (HE) staining and Masson staining...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779270/-protective-effects-of-hydrogen-rich-medium-on-lipopolysaccharides-induced-injury-in-human-periodontal-ligament-cells
#9
Min Zhou, Zuo-Lin Wang
OBJECTIVE: In this study, lipopolysaccharides (LPS) was used to damage human periodontal ligament cells (hPDLCs) and consequently investigate the protective effects of hydrogen on reducing oxidative stress and cell apoptosis rate. METHODS: hPDLCs were isolated, and then cultured with normal medium+1 μg·mL⁻¹ LPS or with hydrogen-rich medium+
1 μg·mL⁻¹ LPS. Cell proliferation activity was assessed using a cell counting kit-8 (CCK-8), and lactic dehydrogenase (LDH) release was also detected...
April 1, 2018: Hua Xi Kou Qiang Yi Xue za Zhi, Huaxi Kouqiang Yixue Zazhi, West China Journal of Stomatology
https://www.readbyqxmd.com/read/29779267/%C3%AE-synuclein-activates-innate-immunity-but-suppresses-interferon-%C3%AE-expression-in-murine-astrocytes
#10
Jintang Wang, Zheng Chen, Jeremy Walston, Peisong Gao, Maolong Gao, Sean X Leng
Glial activation and neuroinflammation contribute to pathogenesis of neurodegenerative diseases, linked to neuron loss and dysfunction. α-Synuclein (α-syn), as a metabolite of neuron, can induce microglia activation to trigger innate immune response. However, whether α-syn, as well as its mutants (A53T, A30P and E46K), induces astrocyte activation and inflammatory response is not fully elucidated. In this study, we used A53T mutant and wildtype α-syns to stimulate primary astrocytes in dose- and time-dependent manners (0...
May 19, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29779264/compliance-to-follow-up-and-adherence-to-medication-in-hypertensive-patients-in-an-urban-informal-settlement-in-kenya-comparison-of-three-models-of-care
#11
Ng'endo Kuria, Anthony Reid, Philip Owiti, Hannock Tweya, Caleb Kipkurui Kibet, Lilian Mbau, Marcel Manzi, Victor Murunga, Tecla Namusonge, Joseph Kibachio
OBJECTIVE: To determine and compare, among three models of care, compliance to scheduled clinic appointments and adherence to anti-hypertensive medication of patients in an informal settlement of Kibera, Kenya. METHODS: Routinely collected patient data were used from three health facilities, six walkway clinics and one weekend/church clinic. Patients were eligible if they had received hypertension care for more than six months. Compliance with clinic appointments and self-reported adherence to medication were determined from clinic records and compared using the Chi-square test...
May 19, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29779262/-salivary-exrna-biomarkers-to-detect-gingivitis-and-monitor-disease-regression
#12
Karolina Elżbieta Kaczor-Urbanowicz, Harsh M Trivedi, Patricia O Lima, Paulo M Camargo, William V Giannobile, Tristan R Grogan, Frederico O Gleber-Netto, Yair Whiteman, Feng Li, Hyo Jung Lee, Karan Dharia, Katri Aro, Carmen Martin Carerras-Presas, Saarah Amuthan, Manjiri Vartak, David Akin, Hiba Al-Adbullah, Kanika Bembey, Perry R Klokkevold, David Elashoff, Virginia Monsul Barnes, Rose Richter, William DeVizio, James G Masters, David Wong
AIM: This study tests the hypothesis that salivary extracellular RNA (exRNA) biomarkers can be developed for gingivitis detection and monitoring disease regression. MATERIALS AND METHODS: Salivary exRNA biomarker candidates were developed from a total of 100 gingivitis and non-gingivitis individuals using Affymetrix's expression microarrays. The top ten differentially expressed exRNAs were tested in a clinical cohort to determine if the discovered salivary exRNA markers for gingivitis were associated with clinical gingivitis and disease regression...
May 19, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29779260/fifteen-years-of-pmtct-hiv-and-syphilis-outcomes-in-haiti-from-monotherapy-to-option-b
#13
Marie Marcelle Deschamps, Deanna Jannat-Khah, Vanessa Rouzier, Jerry Bonhomme, Julma Pierrot, Myung Hee Lee, Elaine Abrams, Jean Pape, Margaret L McNairy
OBJECTIVE: To evaluate mother and infant outcomes in the largest prevention of mother-to-child-transmission (PMTCT) program in Haiti in order to identify gaps towards elimination of HIV and syphilis. METHODS: Based on retrospective data from HIV+ pregnant women and their infants enrolled in PMTCT care from 1999-2014, we assessed maternal enrolment in PMTCT, receipt of antiretrovirals before delivery, maternal retention through delivery, as well as infant enrolment in PMTCT, HIV testing, and HIV infection...
May 19, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29779258/hyperpolarized-porous-silicon-nanoparticles-potential-theragnostic-material-for-%C3%A2-%C3%A2-si-magnetic-resonance-imaging
#14
Hyeonglim Seo, Ikjang Choi, Nicholas Whiting, Jingzhe Hu, Quy Son Luu, Shivanand Pudakalakatti, Caitlin McCowan, Yaewon Kim, Niki Zacharias, Seunghyun Lee, Pratip Bhattacharya, Youngbok Lee
Porous silicon nanoparticles have recently garnered attention as potentially-promising biomedical platforms for drug delivery and medical diagnostics. Here, we demonstrate porous silicon nanoparticles as contrast agents for ²⁹Si magnetic resonance imaging. Size-controlled porous silicon nanoparticles were synthesized by magnesiothermic reduction of silica nanoparticles and were surface activated for further functionalization. Particles were hyperpolarized via dynamic nuclear polarization to enhance their ²⁹Si MR signals; the particles demonstrated long ²⁹Si spin-lattice relaxation (T₁) times (~ 25 mins), which suggests potential applicability for medical imaging...
May 20, 2018: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/29779255/outcome-following-right-extended-split-liver-transplantation-in-the-recent-transplant-era-single-centre-analysis-of-a-german-transplant-centre
#15
Uta Herden, Lutz Fischer, Martina Koch, Jun Li, Eike-Gert Achilles, Björn Nashan
INTRODUCTION: When a sufficiently high-quality liver is available, classic liver graft splitting is performed. In such cases, a small child receives the left-lateral split graft, with subsequent transplantation of the right-extended graft in an adult. METHODS: We analysed 64 patients who received right-extended liver grafts from 2007-2015, and compared outcomes between cases of external versus in-house graft splitting. RESULTS: We found excellent donor data and comparable recipient characteristics...
May 20, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29779244/diversity-of-epicotyl-dormancy-among-tropical-montane-forest-species-in-sri-lanka
#16
Yasoja S Athugala, K M G G Jayasuriya, A M T A Gunarathne, Carol C Baskin
Fruiting season of many Sri Lankan tropical montane species is not synchronized and may not occur when conditions are favorable for seedling establishment. We hypothesized that species with different fruiting seasons have different seed dormancy mechanisms to synchronize timing of germination with a favorable season for establishment. Using six species with different fruiting seasons, we tested this hypothesis. Germination and imbibition of intact and manually-scarified seeds were studied. Effect of GA3 on germination was examined...
May 20, 2018: Plant Biology
https://www.readbyqxmd.com/read/29779240/synthesis-characterization-and-reactivity-of-3-mercaptopyruvic-acid
#17
Erwan Galardon, Jean-Chrstophe Lec
A synthesis of the sulfur metabolic compound 3-mercaptopyruvic acid (3-MPH) is reported and allowed its isolation and characterization for the first time. Detailed kinetic, thermodynamic and spectroscopic studies of its complex behaviour in solution are discussed.
May 20, 2018: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/29779234/testing-the-role-of-climate-in-speciation-new-methods-and-applications-to-squamate-reptiles-lizards-and-snakes
#18
Tereza Jezkova, John J Wiens
Climate may play important roles in speciation, such as causing the range fragmentation that underlies allopatric speciation (through niche conservatism) or driving divergence of parapatric populations along climatic gradients (through niche divergence). Here, we developed new methods to test the frequency of climate niche conservatism and divergence in speciation, and applied it to species pairs of squamate reptiles (lizards and snakes). We used a large-scale phylogeny to identify 242 sister-species pairs for analysis...
May 19, 2018: Molecular Ecology
https://www.readbyqxmd.com/read/29779233/long-term-high-intensity-sound-stimulation-inhibits-h-current-i-h-in-ca1-pyramidal-neurons
#19
A O S Cunha, C C Ceballos, J L de Deus, R M Leão
Afferent neurotransmission to hippocampal pyramidal cells can lead to long-term changes to their intrinsic membrane properties and affect many ion currents. One of the most plastic neuronal currents is the hyperpolarization activated cationic current (Ih ), which changes in CA1 pyramidal cells in response to many types of physiological and pathological processes, including auditory stimulation. Recently we demonstrated that long-term potentiation (LTP) in rat hippocampal Schaffer-CA1 synapses is depressed by high-intensity sound stimulation...
May 19, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29779231/specialist-perioperative-allergy-clinic-services-in-the-uk-2018-results-from-the-royal-college-of-anaesthetists-sixth-national-audit-project-nap6-investigation-of-perioperative-anaphylaxis
#20
W Egner, T M Cook, T Garcez, S Marinho, H Kemp, D N Lucas, K Floss, S Farooque, H Torevell, M Thomas, K Ferguson, S Nasser, S Karanam, K-L Kong, N McGuire, M Bellamy, A Warner, J Hitchman, L Farmer, N J N Harper
BACKGROUND: The Royal College of Anaesthetists 6th National Audit Project examined Grade 3-5 perioperative anaphylaxis for one year in the UK. OBJECTIVE: To describe the causes and investigation of anaphylaxis in the NAP6 cohort, in relation to published guidance and previous baseline survey results. METHODS: We used a secure registry to gather details of Grade 3-5 perioperative anaphylaxis. Anonymous reports were aggregated for analysis and reviewed in detail...
May 19, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
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