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Anorectal dermatology

Alessandra Latini, Mauro Zaccarelli, Maria Grazia Paglia, Maria Gabriella Donà, Amalia Giglio, Domenico Moretto, Antonella Vulcano, Massimo Giuliani, Manuela Colafigli, Marina Ambrifi, Fulvia Pimpinelli, Antonio Cristaudo
BACKGROUND: Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by L1, L2, L3 serovars of C. trachomatis (CT). Since 2003, LGV cases have been increasing in Europe. Aim of this report is to describe the LGV cases diagnosed in the largest STI center in Rome, Italy, from 2000 to 2016. This report shows that two clinically and epidemiologically different series of cases exist, and that, at present, the ano-rectal LGV represents the clinical variant occurring more frequently among men having sex with men (MSM), particularly those HIV-infected...
June 2, 2017: BMC Infectious Diseases
Murugan Swamiappan
Anogenital pruritus is defined as intense itching, acute or chronic, affecting the anal, perianal, perineal and genital skin, which is a dominant problem in the course of various cutaneous and systemic conditions. It is one of the common, extremely annoying symptom for which patients attend the Dermatology Outpatient Department (OPD). Anogenital skin is highly sensitive to soaps, perfumes, clothing and superficial trauma and it is more prone for itchy dermatoses as a result of warmth, friction, lack of aeration, sweating and occlusive inner garments...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
S Lorcy, C Gaudy-Marqueste, D Botta, I Portal, N Quiles, V Oulies, J Mancini, J-J Grob, M-A Richard
BACKGROUND: Telaprevir, sale of which was suspended, has been approved in combination with pegylated interferon and ribavirin (triple therapy) in the treatment of chronic hepatitis C virus (HCV). Skin eruptions and isolated cases of severe cutaneous adverse reactions (SCAR) have been reported. AIMS: Our aim was to assess the incidence of skin eruption and the clinical characteristics of mucocutaneous adverse events (AE), and to identify potential risk factors for telaprevir-associated skin eruption...
May 2016: Annales de Dermatologie et de Vénéréologie
Elżbieta Kłujszo, Piotr Parcheta, Dorota Zarębska-Michaluk, Ewa Ochwanowska, Anna Witkowska, Adriana Rakowska, Lidia Rudnicka, Wiesław Kryczka
BACKGROUND: Combination therapy with pegylated interferon, ribavirin and a first-generation NS3/4A protease inhibitor, telaprevir or boceprevir, is the new strategy for treatment of genotype 1 chronic hepatitis C virus infection. This combination improves therapeutic efficacy but it also increases the risk of adverse events. OBJECTIVE: The aim of the study was to analyze frequency and severity of dermatological adverse events during protease inhibitor-based therapy and to evaluate the risk factors for their development...
December 31, 2014: Journal of Dermatological Case Reports
Mohammad Gharedaghi, Fariborz Samini, Hosein Mashhadinejad, Mahdi Khajavi, Mohammad Samini
BACKGROUND: Many of the patients with tethered cord syndrome (TCS) are admitted because of neurological symptoms, while some are admitted because of their orthopedic, urologic, anorectal, and dermatologic manifestations. Consequently, this study aimed to evaluate the importance of early diagnosis and treatment of tethered cord syndrome on patient outcome. METHODS: Fourty-three patients who underwent surgery because of tethered cord syndrome from 2006 to 2010 were studied...
June 2014: Archives of Bone and Joint Surgery
Shyam B Verma, Uwe Wollina
Two cases of infantile perianal pyramidal protrusions (IPPP), one pyramidal in shape and one leaf shaped, are being described by us. Both were notable for coexisting hemangiomas in the close vicinity. To the best of our knowledge we are reporting these two variants of IPPP with the associated neighboring hemangiomas for the first time in Indian dermatologic literature. We suggest that this presentation may be a part of one of the syndromes that comprise anorectal malformations with hemangiomas like PELVIS syndrome and others mentioned in the table...
January 2014: Indian Journal of Dermatology
Georgi Tchernev, Kristina Semkova, Stanislav Philipov, Radoswet Gornev, Julian Ananiev, Uwe Wollina
Anorectal malignant melanoma (ARMM) is an extremely rare condition, often misdiagnosed and mistreated until development of metastatic disease. Clinical presentation mimicking hemorrhoids is a well-known pitfall. We present a male patient with hemorrhoidal nodules who was referred to the policlinic of dermatology for management of anal pruritus. A dark macule was detected over one of the hemorrhoidal nodules histologically verified as melanoma. Subsequent CT and PET/CT showed lymph nodes involvement and the patient underwent wide local excision (WSE) followed by abdominoperineal resection (APR)...
November 2013: Wiener Medizinische Wochenschrift
Helen Köhl, Stephan Lautenschlager
No abstract text is available yet for this article.
November 13, 2013: Praxis
F Hali, K Khadir, K Zouhair, H Benchikhi, S Azzouzi
BACKGROUND: The gluteal region is a complex area of the body that may be the seat of several diseases with dermatological manifestations. The purpose of this series was to study the aetiological profile of suppurative lesions of the gluteal region in patients in Morocco. PATIENTS AND METHODS: A retrospective study was carried out on patients presenting suppuration of the gluteal region hospitalised in our department between 1987 and 2008. The epidemiological, clinical and aetiological data for 60 cases were reviewed...
October 2010: Annales de Dermatologie et de Vénéréologie
Dean A Hertzler, John J DePowell, Charles B Stevenson, Francesco T Mangano
Tethered cord syndrome (TCS) is a clinical condition of various origins that arises from tension on the spinal cord. Radiographic findings may include the conus medullaris in a lower than normal position, fatty infiltration of the filum terminale, lipomyelomeningocele, myelomeningocele, myelocystocele, meningocele, split cord malformations, dermal sinus, anorectal malformations, and intraspinal tumors. The clinical constellation of signs and symptoms associated with TCS may include dermatologic, urological, gastrointestinal, neurological, and orthopedic findings...
July 2010: Neurosurgical Focus
Jivko Kamarashev, Christoph E Riess, Josephine Mosimann, Severin Läuchli
BACKGROUND: Whereas until 2003 Lymphogranuloma venereum (LGV) was rare in industrialised countries, there have been increasing reports of cases of LGV proctitis in men having sex with men (MSM) over the last six years in Europe, America and Australia. PATIENTS AND METHODS: After the alarming message from the Netherlands in 2003, physicians in a dermatological and STI private clinic in Zurich started examining rectal swabs from patients with proctitis for LGV serovars of C...
April 3, 2010: Swiss Medical Weekly
Ahmet Oğuz Hasdemir, Oktay Büyükaşik, Cavit Cöl
INTRODUCTION AND HYPOTHESIS: Our aim was to review our experience with Fournier's gangrene in female patients. METHODS: A retrospective review of ten consecutive female patients with Fournier's gangrene was performed. Etiological and predisposing factors, causative microbiological organisms, and clinical outcome were investigated. RESULTS: Mean age of the patients was 52.7 years, and the mean duration of hospitalization was 17.6 days. The etiologic origin of the gangrene was anorectal, dermatological, and urogenital infection in 50%, 20%, and 10% of patients, respectively...
December 2009: International Urogynecology Journal and Pelvic Floor Dysfunction
S Siddiqi, V Vijay, M Ward, R Mahendran, S Warren
INTRODUCTION: Pruritus ani is a common condition with many causes, predominately anorectal pathology. There are some new insights and therapies, but the most recommendations are based on low-level evidence. PATIENTS AND METHODS: A literature search was carried out using Medline and the internet with the keywords 'pruritus ani' from 1950 to 2007. RESULTS: A review of the evidence is presented and a management plan based on the elimination of irritants and scratching, general control measures and active treatment measures is offered...
September 2008: Annals of the Royal College of Surgeons of England
F G Bader, R Bouchard, A Lubienski, R Keller, L Mirow, R Czymek, J K Habermann, H-P Bruch, U J Roblick
Diagnostics and therapy of anorectal disorders remain a surgical question. In close cooperation between different departments (radiology and gastroenterology, urology and gynecology, dermatology and psychology), the role of radiologic imaging is of growing importance. Exact knowledge of functional anatomy and precise clinical examination constitute the basis of the according therapeutic strategies. In this context radiology has contributed decisively. Developments in imaging techniques, e.g. dynamic MRI, highly contributed to better understanding of complex functional pelvic floor disorders...
May 2008: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
Maureen S Macmillan, Mary Wells, Sheila MacBride, Gillian M Raab, Alastair Munro, Hugh MacDougall
PURPOSE: We present the results of a randomized controlled clinical trial that evaluated the effect of a hydrogel or dry dressing on the time to healing of moist desquamation after radiotherapy to the head-and-neck, breast, or anorectal areas. METHODS AND MATERIALS: A total of 357 patients were randomized before radiotherapy to receive simple dry dressings (Tricotex) or a hydrogel (Intrasite), with Tricotex as a secondary dressing. Patients were instructed to use their dressings from the onset of moist desquamation, if it occurred...
July 1, 2007: International Journal of Radiation Oncology, Biology, Physics
H Bäcker, M Dobmeier, M Landthaler
Anorexia nervosa (AN) is one of the most dangerous psychiatric diseases; it bears a poor prognosis, marked addictive potential and a high risk of suicide. The earlier the eating disorder is diagnosed and treated, the better the prognosis of AN. A number of dermatological conditions may be associated with AN, although none are specific for AN. These findings include xerosis cutis, effluvium, gingivitis, cheilitis, acne and nail lesions. The cutaneous findings often observed in AN may be localized to the hands ("anorectic hand"), which should therefore always be examined if AN is suspected...
March 2007: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
Scott Edelman, Peter A S Johnstone
PURPOSE: We report toxicity and survival data of human immunodeficiency virus (HIV)-infected men with anal carcinoma treated with combined modality therapy (CMT) of radiotherapy and concurrent chemotherapy. METHODS AND MATERIALS: A retrospective review was performed on the records of 17 HIV-positive patients with anal squamous cell carcinoma treated with CMT at our institution between 1991 and 2004. Radiotherapy consisted of 30.6 to 45 Gy to the pelvis, total dose of 50...
September 1, 2006: International Journal of Radiation Oncology, Biology, Physics
R Gurfinkel, Y Slovik, R Glezinger, S Walfisch
BACKGROUND: Fournier's gangrene is recognized as a synergistic necrotizing fasciitis of the perineum and abdominal wall along with the scrotum and penis in men and the vulva in women. The major sources of Fournier's Gangrene are dermatologic, anorectal and genitourinary infections. Although anorectum is remarkably rich in bacterial flora, transanal procedures are generally free of infectious or septic complications. Nevertheless, five cases of Fournier's gangrene post hemorrhoidectomy have been published...
June 2005: Harefuah
Mary Wells, Maureen Macmillan, Gillian Raab, Sheila MacBride, Nancy Bell, Karen MacKinnon, Hugh MacDougall, Leslie Samuel, Alastair Munro
BACKGROUND AND PURPOSE: Evidence on which to base decisions about the management of radiation skin reactions is lacking. The purpose of this study was to investigate whether sucralfate or aqueous cream reduced acute skin toxicity during radiotherapy to the head and neck, breast or anorectal area (phase A), and to evaluate the effect of hydrogels and dry dressings on moist desquamation (phase B). This paper presents the results of phase A. PATIENTS AND METHODS: Three hundred and fifty seven patients were randomised to apply aqueous cream, sucralfate cream or no cream to the irradiated area from day one of radical radiotherapy treatment...
November 2004: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
No abstract text is available yet for this article.
May 1954: Nebraska State Medical Journal
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