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https://www.readbyqxmd.com/read/28648026/-serum-uric-acid-is-associated-with-disease-severity-and-an-important-predictor-for-clinical-outcome-in-patients-with-pulmonary-hypertension
#1
D L Luo, C J Zhang, Y G Huang, T Huang, H Z Li
Objective: The growing body of literature showed a link between uric acid and pulmonary hypertension (PH), but the impact of hyperuremia on outcome of patients with PH has not been well defined. Therefore, the present study was performed to analyze the impact of uric acid on outcome of PH patients. Methods: One hundred seventy-three PH patients (112 females, mean age 38 years old), who were hospitalized in our department between January 2010 and December 2015, were included in our study, the PH diagnosis was made based on right heart catheterization examination result (mean pulmonary artery pressure≥25 mmHg(1 mmHg=0...
June 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/28648012/-validation-of-the-caprini-risk-assessment-model-for-venous-thromboembolism-in-chinese-hospitalized-patients-in-a-general-hospital
#2
X Y Luo, F X Zhang
Objective: To assess the validity of Caprini risk assessment model in prediction of venous thromboembolism in Chinese hospitalized patients in a general hospital. Methods: Medical record review was performed in Beijing Shijitan Hosital for all eligible hospitalized patients who underwent screening for venous thromboembolism between January and December 2015. The Caprini score of patients with or without venous thromboemboilism and incidence of venous thromboembolism in patients with various Caprini risk levels, surgery and medical patients was compared...
June 27, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28647999/-relationship-between-the-ratio-of-neutrophil-lymphocyte-and-risk-stratification-prognosis-in-patients-with-non-st-elevation-acute-coronary-syndrome
#3
Y Wang, S J Jia, Z Chi
Objective: To investigate the value of neutrophil to lymphocyte ratio (NLR) in predicting risk stratification and prognosis in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS). Methods: A total of 227 NSTE-ACS patients after percutaneous coronary intervention (PCI) were collected from September 2012 to September 2014 in Beijing Anzhen Hospital.Groups: (1)According to NLR, the patients were divided into 3 groups: NLR<2.20 group; 2.2≤NLR<3.33 group; NLR≥3.33 group.(2)According to the global registry of acute coronary events (GRACE) score, the patients were divided into 3 groups: Low-risk group, Medium-risk group and High-risk group...
June 20, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28647996/-curative-effects-and-influenced-factors-of-primary-chemotherapy-with-single-agent-methotrexate-on-low-risk-gestational-trophoblastic-neoplasia
#4
X D Wu, L L Chen, T Shen, S S Chen, Q Q Chen, J L Qin, Y F Fu, W G Lü
Objective: To evaluate the efficacy of primary chemotherapy with single-agent methotrexate (MTX) for low-risk gestational trophoblastic neoplasia and to analysis the influenced factors. Methods: We retrospectively reviewed 259 cases with low-risk gestational trophoblastic neoplasia whose primary chemotherapies were MTX 0.4 mg·kg(-1) (maximum 25 mg) daily for 5 days every other week. Patients' data between January 2001 and June 2015 was collected and the relationships of different factors to outcomes of chemotherapy were also evaluated...
June 20, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28647971/-association-between-body-fat-percentage-visceral-fat-index-and-cardiometabolic-risk-factor-clustering-among-population-aged-35-year-old-or-over-in-tibet-autonomous-region-and-xinjiang-uygur-autonomous-region
#5
J L Wang, Z Chen, L F Zhang, X Wang, Y Dong, J Y Nie, C Y Zheng, L Shao, Y Tian, Z W Wang
Objective: To investigate the association between body fat percentage (BFP), visceral fat index (VFI) and Cardiometabolic Risk Factor Clustering (CRFC), among population aged 35 or older in Tibet and Xinjiang areas. Methods: Using the stratified multi-stage random sampling method, 7 571 residents aged 35 or above were examined with international standardized examination between 2015 and 2016. Of the eligible 5 643 participants, association of BFP and VFI with CRFC was defined as having two or more of the four risk factors: hypertension, diabetes mellitus, high TG and low HDL-C, at the same time...
June 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28647915/impact-of-the-21-gene-recurrence-score-on-outcome-in-patients-with-invasive-lobular-carcinoma-of-the-breast
#6
Scott Kizy, Jing Li Huang, Schelomo Marmor, Todd M Tuttle, Jane Yuet Ching Hui
PURPOSE: Invasive lobular carcinoma (ILC) of the breast has unique clinicopathologic characteristics, compared to invasive ductal carcinoma. The role of the 21-gene Recurrence Score (RS) has not been clearly defined for ILC. We sought to determine the prognostic value of RS and the impact of adjuvant chemotherapy on long-term survival in patients with ILC. METHODS: Utilizing the Surveillance, Epidemiology and End Results database from 2004 to 2013, we identified records of women aged 18-74 years, diagnosed with estrogen receptor (ER)-positive ILC (stage I to III) with RS available...
June 24, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28647904/a-cost-precision-model-for-marine-environmental-monitoring-based-on-time-integrated-averages
#7
Ulf Båmstedt, Sonia Brugel
Ongoing marine monitoring programs are seldom designed to detect changes in the environment between different years, mainly due to the high number of samples required for a sufficient statistical precision. We here show that pooling over time (time integration) of seasonal measurements provides an efficient method of reducing variability, thereby improving the precision and power in detecting inter-annual differences. Such data from weekly environmental sensor profiles at 21 stations in the northern Bothnian Sea was used in a cost-precision spatio-temporal allocation model...
July 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28647900/breast-cancer-risk-associated-with-genotype-polymorphisms-of-the-aurora-kinase-a-gene-aurka-a-case-control-study-in-a-high-altitude-ecuadorian-mestizo-population
#8
Andrés López-Cortés, Alejandro Cabrera-Andrade, Fabián Oña-Cisneros, Felipe Rosales, Malena Ortiz, Eduardo Tejera, César Paz-Y-Miño
Breast cancer (BC) is the leading cause of cancer related death among women in 2014. The AURKA gene that encodes the protein called Aurora kinase A plays an important role in the progression of the cell cycle, by controlling and promoting the entry into the phase of mitosis. The single nucleotide polymorphism AURKA T91A (rs2273535) (Phe21Ile) has been identified as functional alternator of this kinase, the Ile allele is associated with the occurrence of chromosome segregation errors and tumor progression. Therefore, it is essential to know how BC risk is associated with histopathological characteristics, immunohistochemical characteristics, and genotype polymorphism in a high altitude Ecuadorian mestizo population...
June 24, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28647899/value-of-contrast-enhanced-mri-in-the-differentiation-between-nasopharyngeal-lymphoid-hyperplasia-and-t1-stage-nasopharyngeal-carcinoma
#9
Ming-Liang Wang, Xiao-Er Wei, Meng-Meng Yu, Wen-Bin Li
OBJECTIVES: To investigate the value of contrast-enhanced MRI in differentiation between benign nasopharyngeal lymphoid hyperplasia (NPLH) and T1 stage nasopharyngeal carcinoma (NPC). METHODS: Eighty-six NPLH patients and 38 T1 stage NPC patients who underwent a contrast-enhanced MRI and an endoscopic biopsy were included. The patients' symptoms and MRI features of nasopharyngeal mucosal thickening like location, symmetry, nasopharyngeal bubble, superficial mucus, nasopharyngeal retention cysts, serrated protrusions, contrast-enhancement type were documented...
June 24, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28647897/varicocele-and-semen-quality-a-retrospective-case-control-study-of-4230-patients-from-a-single-centre
#10
F Pallotti, D Paoli, T Carlini, A R Vestri, G Martino, A Lenzi, F Lombardo
PURPOSE: The aim of the present study is to assess impairment of spermatogenesis induced by varicocele in, to our knowledge, the largest single-centre caseload available to date. MATERIALS AND METHODS: We conducted a retrospective study on 4230 consecutive patients attending our Department for andrological outpatient assessment and preconception check-ups between 2011 and 2014. A total of 2113 patients had varicocele (Group V), while the remaining 2117 were selected as the control group (Group C)...
June 24, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28647896/omics-based-hybrid-prediction-in-maize
#11
Matthias Westhues, Tobias A Schrag, Claas Heuer, Georg Thaller, H Friedrich Utz, Wolfgang Schipprack, Alexander Thiemann, Felix Seifert, Anita Ehret, Armin Schlereth, Mark Stitt, Zoran Nikoloski, Lothar Willmitzer, Chris C Schön, Stefan Scholten, Albrecht E Melchinger
Complementing genomic data with other "omics" predictors can increase the probability of success for predicting the best hybrid combinations using complex agronomic traits. Accurate prediction of traits with complex genetic architecture is crucial for selecting superior candidates in animal and plant breeding and for guiding decisions in personalized medicine. Whole-genome prediction has revolutionized these areas but has inherent limitations in incorporating intricate epistatic interactions. Downstream "omics" data are expected to integrate interactions within and between different biological strata and provide the opportunity to improve trait prediction...
June 24, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/28647855/short-term-annoyance-from-nocturnal-aircraft-noise-exposure-results-of-the-norah-and-strain-sleep-studies
#12
Julia Quehl, Uwe Müller, Franco Mendolia
PURPOSE: The German Aerospace Center (DLR) investigated in the NORAH sleep study the association between a distinct change in nocturnal aircraft noise exposure due to the introduction of a night curfew (11:00 p.m.-5:00 a.m.) at Frankfurt Airport and short-term annoyance reactions of residents in the surrounding community. Exposure-response curves were calculated by random effects logistic regression to evaluate the aircraft noise-related parameters (1) number of overflights and (2) energy equivalent noise level LASeq for the prediction of short-term annoyance...
June 24, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/28647850/wound-healing-protein-profiles-in-the-postoperative-exudate-of-bisphosphonate-related-osteonecrosis-of-mandible
#13
Soung Min Kim, Mi Young Eo, Yun Ju Cho, Yeon Sook Kim, Suk Keun Lee
Recurrent bacterial infections in cases of bisphosphonate-related osteonecrosis of jaw (BRONJ) frequently occur. Therefore, BRONJ are usually treated by radical saucerization followed by intensive antibiotic medications without bisphosphonate therapy. The postoperative exudate (POE) from BRONJ lesions may directly indicate the inflammatory status of osteomyelitis in patients, but so far, the POE has rarely been examined for its expression of various cytokines and wound healing proteins. A total of 27 cases of BRONJ, which involved the mandible, were selected and their individual POE collected 6 h, 1 day, and 2 days after surgical intervention was analyzed by immunoprecipitation high performance liquid chromatography (IP-HPLC)...
June 24, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28647839/do-bumble-bee-bombus-impatiens-queens-signal-their-reproductive-and-mating-status-to-their-workers
#14
Etya Amsalem, Mario Padilla, Paul M Schreiber, Naomi S Altman, Abraham Hefetz, Christina M Grozinger
Reproduction in social insect societies reflects a delicate balance between cooperation and conflict over offspring production, and worker reproduction is widespread even in species showing strong reproductive skew in favor of the queen. To navigate these conflicts, workers are predicted to develop the means to estimate the queen's fecundity - potentially through behavioral and/or chemical cues - and to adjust their reproduction to maximize their fitness. Here, we introduced bumble bee, Bombus impatiens, workers to queens of different mating and reproductive status and examined worker reproduction and expression levels of two genes which were previously shown to be sensitive to the presence of the queen, vitellogenin and Krüppel-homolog 1...
June 24, 2017: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/28647814/the-effects-of-variable-practice-on-locomotor-adaptation-to-a-novel-asymmetric-gait
#15
Jacob W Hinkel-Lipsker, Michael E Hahn
Very little is known about the effects of specific practice on motor learning of predictive balance control during novel bipedal gait. This information could provide an insight into how the direction and magnitude of predictive errors during acquisition of a novel gait task influence transfer of balance control, as well as yield a practice protocol for the restoration of balance for those with locomotor impairments. This study examined the effect of a variable practice paradigm on transfer of a novel asymmetric gait pattern in able-bodied individuals...
June 24, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28647806/pre-anesthetic-stroke-volume-variation-can-predict-cardiac-output-decrease-and-hypotension-during-induction-of-general-anesthesia
#16
Takashi Juri, Koichi Suehiro, Sayaka Tsujimoto, Shigemune Kuwata, Akira Mukai, Katsuaki Tanaka, Tokuhiro Yamada, Takashi Mori, Kiyonobu Nishikawa
This study aimed to assess the reliability of stroke volume variation (SVV) in predicting cardiac output (CO) decrease and hypotension during induction of general anesthesia. Forty-five patients undergoing abdominal surgery under general anesthesia were enrolled. Before induction of anesthesia, patients were required to maintain deep breathing (6-8 times/min), and pre-anesthetic SVV was measured for 1 min by electrical cardiometry. General anesthesia was induced with propofol, remifentanil, rocuronium, and sevoflurane...
June 24, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28647803/chronic-joint-pain-and-handgrip-strength-correlates-with-osteoporosis-in-mid-life-women-a-singaporean-cohort
#17
S Logan, W P P Thu, W K Lay, L Y Wang, J A Cauley, E L Yong
This study aimed to identify novel correlates which may relate to low bone mass at lumbar spine in mid-life Asian women. The possibility of developing a prediction model for osteoporosis (OP) was explored which resulted in a risk assessment tool that performed better than currently available tools. INTRODUCTION: In order to identify novel correlates associated with low spinal bone mineral density (BMD) in mid-life women, we examined a large number of lifestyle and medical and performance measurements and developed a prediction model for triage to BMD scanning...
June 24, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28647801/prognostic-factors-of-atrial-fibrillation-following-coronary-artery-bypass-graft-surgery
#18
Mantas Kievišas, Vytenis Keturakis, Egidijus Vaitiekūnas, Lukas Dambrauskas, Loreta Jankauskienė, Šarūnas Kinduris
OBJECTIVE: Postoperative atrial fibrillation (POAF) is the most common complication after cardiac surgery. To prevent this complication, routine pharmacological prophylactic drugs could be administered. Our study aimed to analyze the various perioperative factors associated with the development of POAF after coronary artery bypass graft (CABG) surgery. METHODS: This prospective study included 617 patients, who received CABG surgery in the year 2014. RESULTS: There were 429 (69...
June 24, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28647791/premonitory-symptoms-of-migraine-in-childhood-and-adolescence
#19
REVIEW
N Karsan, P Prabhakar, P J Goadsby
PURPOSE OF REVIEW: Premonitory symptoms in migraine; symptoms occurring before the onset of migraine pain or aura, are an increasingly recognised area of interest within headache research. It has been recently documented in the literature that these symptoms also occur in children and adolescents, with a comparable phenotype to adults. This review discusses the wide presentation of premonitory symptoms in migraine in children and adolescents, and the importance of understanding how these early symptoms are mediated in order to ensure that targeted abortive therapies are developed in the future...
July 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28647783/a-sample-predictive-model-for-intraocular-pressure-following-laser-in-situ-keratomileusis-for-myopia-and-an-intraocular-pressure-constant
#20
Ayse Ebru Bahadir Kilavuzoglu, Tahir Kansu Bozkurt, Cemile Banu Cosar, Asım Bozkurt Sener
PURPOSE: To describe a sample predictive model for intraocular pressure (IOP) following laser in situ keratomileusis (LASIK) for myopia and an IOP constant. METHODS: The records of patients that underwent LASIK for myopia and myopic astigmatism via WaveLight Allegretto Wave Eye-Q 400 Hz excimer laser and Hansatome XP microkeratome were retrospectively reviewed. Patients with no systemic or ocular disease other than myopia or myopic astigmatism were included in the study...
June 24, 2017: International Ophthalmology
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