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Risk factor rheumatic heart disease

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https://www.readbyqxmd.com/read/27906042/what-is-the-impact-of-biologic-therapies-on-common-co-morbidities-in-patients-with-rheumatoid-arthritis
#1
REVIEW
Jenny Humphreys, Kimme Hyrich, Deborah Symmons
Biologic therapies have revolutionised disease control in patients with rheumatoid arthritis (RA). Theoretically, they have the potential to influence co-morbid disease associated with RA through better control of systemic inflammation. Conversely, co-morbidity may occur as an adverse effect of the drugs. The latest evidence from observational data shows an increased risk of infection in the first 6 months of treatment with tumour necrosis factor inhibitor (TNFi) therapies and potentially other biologic therapies...
December 1, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/27892897/the-importance-of-selected-spices-in-cardiovascular-diseases
#2
Bartosz Kulczyński, Anna Gramza-Michałowska
Cardiovascular diseases are the leading cause of death worldwide. Literature data indicate that, due to these diseases, approximately 17.5 million people died in 2012. Types of cardiovascular disease include ischemic heart disease, cerebrovascular disease, peripheral vascular disease, congenital heart disease, rheumatic heart disease, cardiomyopathy and arrhythmia. Proper nutrition is an important factor in reducing the risk of cardiovascular events. An interesting element of our diets is spices. For thousands of years, they have been used in the treatment of many diseases: bacterial infections, coughs, colds, and liver diseases...
November 14, 2016: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/27886692/cardiovascular-disease-risk-in-patients-with-rheumatic-diseases
#3
REVIEW
Rachel H Mackey, Lewis H Kuller, Larry W Moreland
Evidence suggests the greater than 1.5 increased risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA) is related to an accelerated burden of subclinical atherosclerosis that develops before the diagnosis of RA. Dyslipidemia in RA is better quantified by lipoproteins and apolipoproteins than cholesterol levels. Current risk factors likely underestimate CVD risk partly by underestimating prior risk factor levels. To reduce CVD risk in RA, control disease activity and aggressively treat CVD risk factors...
February 2017: Clinics in Geriatric Medicine
https://www.readbyqxmd.com/read/27883978/outcomes-of-borderline-rheumatic-heart-disease-a-prospective-cohort-study
#4
Geneviève Bertaina, Bernard Rouchon, Bertrand Huon, Nina Guillot, Corinne Robillard, Baptiste Noël, Marie Nadra, Christophe Tribouilloy, Eloi Marijon, Xavier Jouven, Mariana Mirabel
CONTEXT AND AIMS: The advent of systematic screening for rheumatic heart disease (RHD) by echocardiography in endemic regions has led to a new entity: borderline RHD. The pathogenicity and natural history of borderline RHD needs to be addressed. The aim of this study was to assess the outcomes of children detected by echocardiography as having borderline RHD. METHODS: Schoolchildren in 4th grade (i.e., aged 9-10years) who were prospectively echo-screened for RHD (2012-2014) in Nouméa, New Caledonia, were asked to participate...
November 14, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27836917/sugar-dental-caries-and-the-incidence-of-acute-rheumatic-fever-a-cohort-study-of-m%C3%A4-ori-and-pacific-children
#5
Simon Thornley, Roger J Marshall, Katie Bach, Pauline Koopu, Gary Reynolds, Gerhard Sundborn, Win Le Shwe Sin Ei
OBJECTIVE: To determine whether dental caries, as an indicator of cumulative exposure to sugar, is associated with the incidence of acute rheumatic fever and chronic rheumatic heart disease, in Māori and Pacific children aged 5 and 6 years at their first dental visit. MATERIALS AND METHODS: A cohort study was undertaken which linked school dental service records of caries with national hospital discharge and mortality records. Cox models were used to investigate the strength of the association between dental caries and rheumatic fever incidence...
November 11, 2016: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/27793103/the-sphinx-s-riddle-cardiovascular-involvement-in-autoimmune-rheumatic-disease
#6
REVIEW
Sophie Mavrogeni, George Markousis-Mavrogenis, Genovefa Kolovou
Factors leading to Cardiovascular Disease (CVD) in Autoimmune Rheumatic Diseases (ARD) include: a) atherosclerosis and macro-microvascular coronary artery disease b) pericardial, myocardial and vascular inflammation c) heart valve disease d) heart failure and e) pulmonary hypertension.Cardiology utilizes various non-invasive imaging modalities, such as rest/stress Electrocardiogram (ECG), echocardiography, nuclear imaging and more recently Cardiovascular Magnetic Resonance (CMR) to detect ischemic or inflammatory disease in ARD...
October 28, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27773865/air-pollution-in-early-life-and-adult-mortality-from-chronic-rheumatic-heart-disease
#7
David I W Phillips, Clive Osmond, Martin L Williams, Alexander Jones
BACKGROUND: Chronic rheumatic heart disease (RHD) remains a globally important cause of heart disease. The reasons for the continuing high prevalence of this disease are obscure, but it may have its origins in the poor social and economic conditions with which the disease has been consistently and strongly linked. Mortality studies from the UK have suggested the importance of adverse environmental factors in early life; these studies demonstrated specific geographical associations between high rates of chest infection during infancy and subsequent RHD...
October 23, 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/27773412/pulmonary-hypertension-registry-of-kerala-prokerala-rationale-design-and-methods
#8
S Harikrishnan, G Sanjay, M Ashishkumar, Jaideep Menon, G Rajesh, R Krishna Kumar
BACKGROUND: Pulmonary hypertension (PH) is a disease associated with a high morbidity and mortality. There is paucity of data regarding PH from the developing countries including India. Idiopathic pulmonary arterial hypertension is the most important etiological factor in the western world, but PH secondary to rheumatic heart disease, chronic obstructive pulmonary disease and untreated congenital heart disease could well be the predominant causes in developing countries like India. The main objective of the PROKERALA study - Pulmonary hypertension Registry Of Kerala is to collect data regarding the etiology, practice patterns and one-year outcomes of patients diagnosed to have PH...
September 2016: Indian Heart Journal
https://www.readbyqxmd.com/read/27758878/correlation-of-angiotensin-i-converting-enzyme-gene-insertion-deletion-polymorphism-with-rheumatic-heart-disease-a-meta-analysis
#9
Yulong Tian, Zhongchun Ge, Yuliang Xing, Yan Sun, Jie Ying
Rheumatic heart disease (RHD) is a serious cardiovascular disorder worldwide. Several articles have reported the effect of angiotensin I-converting enzyme gene insertion/deletion (ACE I/D) polymorphism in RHD risk. However, the results still remain inconsistent. The objective of this study was to assess more precise estimations of the relationship between ACE I/D variant and RHD susceptibility. Relevant case-control studies published between January 2000 and 2016 were searched in the electronic databases. The odds ratio (OR) with its 95% confidence interval (CI) was employed to calculate the strength of the effect...
October 10, 2016: Bioscience Reports
https://www.readbyqxmd.com/read/27703088/rheumatic-mitral-valve-disease-is-associated-with-worse-outcomes-in-stroke-a-thailand-national-database-study
#10
Adrian D Wood, Gurdeep S Mannu, Allan B Clark, Somsak Tiamkao, Kannikar Kongbunkiat, Joao H Bettencourt-Silva, Kittisak Sawanyawisuth, Narongrit Kasemsap, Raphae S Barlas, Mamas Mamas, Phyo Kyaw Myint
BACKGROUND AND PURPOSE: Rheumatic valvular heart disease is associated with the increased risk of cerebrovascular events, although there are limited data on the prognosis of patients with rheumatic mitral valve disease (RMVD) after stroke. METHODS: We examined the association between RMVD and both serious and common cardiovascular and noncardiovascular (respiratory and infective) complications in a cohort of hospitalized stroke patients based in Thailand. Factors associated with in-hospital mortality were also explored...
November 2016: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/27481271/the-relevance-of-performing-exercise-test-before-starting-supervised-physical-exercise-in-asymptomatic-cardiovascular-patients-with-rheumatic-diseases
#11
Bárbara Nascimento de Carvalho Klemz, Edgard Torres Dos Reis-Neto, Fábio Jennings, Usmary Sardinha Siqueira, Fábio Kadratz Klemz, Helder Henrique Costa Pinheiro, Emília Inoue Sato, Jamil Natour, Vera Lúcia Szejnfeld, Marcelo de Medeiros Pinheiro
OBJECTIVES: To evaluate the impact and risk factors associated with an abnormal exercise test (ET) in systemic inflammatory rheumatic disease (SIRD) patients before commencing supervised physical exercise. METHODS: A total of 235 SIRD patients were enrolled in three controlled clinical trials, including 103 RA, 42 SLE and 57 AS patients. The control group consisted of 231 healthy, sedentary subjects matched for age, gender and BMI. All performed an ET, according to Bruce's or Ellestad's protocol...
November 2016: Rheumatology
https://www.readbyqxmd.com/read/27448416/obstructive-sleep-apnea-increases-the-perioperative-risk-of-cardiac-valve-replacement-surgery-a-prospective-single-center-study
#12
Ning Ding, Bu-Qing Ni, Hong Wang, Wen-Xiao Ding, Rong Xue, Wei Lin, Zhang Kai, Shi-Jiang Zhang, Xi-Long Zhang
STUDY OBJECTIVES: Sleep apnea is common in patients referred for cardiac valve replacement (CVR). We aimed to determine the association of obstructive sleep apnea (OSA) and central sleep apnea (CSA) with perioperative events in CVR surgery in patients with rheumatic valvular heart disease (RVHD). METHODS: Between April 2010 and April 2014, 290 patients with RVHD undergoing CVR were screened for sleep apnea 1 to 7 days before CVR. Baseline medications, cardiac function, sleep parameters, perioperative events, and related risk factors were evaluated...
October 15, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27418982/left-main-percutaneous-coronary-intervention-and-transcatheter-aortic-valve-replacement-in-a-young-male-with-rheumatic-heart-disease-and-porcelain-aorta
#13
Vinod Chainani, Osman Perez, Ram Hanno, Patrick Hourani, Pablo Rengifo-Moreno, Pedro Martinez-Clark, Carlos E Alfonso
We highlight the presence of a calcified mass in the left main coronary artery without significant atherosclerosis seen in the other coronary arteries or in the peripheral large arteries. In our view, the calcified character of the obstruction and the calcification of the aortic valve are characteristic of a variant type of coronary artery disease (CAD) not associated with the same risk factors as diffuse coronary atherosclerosis, but, in this case, with rheumatic heart disease. This case report also emphasizes the interventional approach for patients with aortic valve stenosis secondary to rheumatic heart disease...
2016: Case Reports in Cardiology
https://www.readbyqxmd.com/read/27407071/long-term-outcomes-from-acute-rheumatic-fever-and-rheumatic-heart-disease-a-data-linkage-and-survival-analysis-approach
#14
Vincent Y F He, John R Condon, Anna P Ralph, Yuejen Zhao, Kathryn Roberts, Jessica L de Dassel, Bart J Currie, Marea Fittock, Keith N Edwards, Jonathan R Carapetis
BACKGROUND: We investigated adverse outcomes for people with acute rheumatic fever (ARF) and rheumatic heart disease (RHD) and the effect of comorbidities and demographic factors on these outcomes. METHODS: Using linked data (RHD register, hospital, and mortality data) for residents of the Northern Territory of Australia, we calculated ARF recurrence rates, rates of progression from ARF to RHD to severe RHD, RHD complication rates (heart failure, endocarditis, stroke, and atrial fibrillation), and mortality rates for 572 individuals diagnosed with ARF and 1248 with RHD in 1997 to 2013 (94...
July 19, 2016: Circulation
https://www.readbyqxmd.com/read/27372607/echocardiographic-prevalence-of-rheumatic-heart-disease-in-brazilian-schoolchildren-data-from-the-provar-study
#15
Bruno R Nascimento, Andrea Z Beaton, Maria Carmo P Nunes, Adriana C Diamantino, Gabriel A L Carmo, Kaciane K B Oliveira, Cassio M Oliveira, Zilda Maria A Meira, Sandra Regina T Castilho, Eduardo L V Lopes, Iara M Castro, Vitória M L R Rezende, Graziela Chequer, Taylor Landay, Allison Tompsett, Antônio Luiz P Ribeiro, Craig Sable
BACKGROUND: Accurate estimates of Rheumatic Heart Disease (RHD) burden are needed to justify improved integration of RHD prevention and screening into the public health systems, but data from Latin America are still sparse. OBJECTIVE: To determine the prevalence of RHD among socioeconomically disadvantaged youth (5-18years) in Brazil and examine risk factors for the disease. METHODS: The PROVAR program utilizes non-expert screeners, telemedicine, and handheld and standard portable echocardiography to conduct echocardiographic screening in socioeconomically disadvantaged schools in Minas Gerais, Brazil...
September 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27355045/a-study-of-clinical-microbiological-and-echocardiographic-profile-of-patients-of-infective-endocarditis
#16
Soumik Ghosh, Ratnakar Sahoo, Ranjit Kumar Nath, Nandini Duggal, Adesh Kumar Gadpayle
Infective endocarditis, a great masquerader, is a clinical entity which may present with a myriad of manifestations. Its changing epidemiological profile has been studied in the previous decades in both the developed and the developing nations. In this study, we strived to uphold the evolving clinical profile and its outcome from a government tertiary care hospital in Northern India. It was a descriptive, cross-sectional, observational study conducted over two years' period involving 44 patients diagnosed with definite infective endocarditis, according to modified Dukes' criteria...
2014: International Scholarly Research Notices
https://www.readbyqxmd.com/read/27354820/atrial-fibrillation-among-the-black-population-in-a-ugandan-tertiary-hospital
#17
Charles Lugero, Davis Kibirige, James Kayima, Charles Kizza Mondo, Jurgen Freers
BACKGROUND: Atrial fibrillation (AF) is the most common type of sustained cardiac arrhythmia in adults, accounting for one-third of hospitalizations due to arrhythmia and related complications worldwide. Previously, rheumatic heart disease was documented as the commonest cause of AF in sub-Saharan Africa. However, due to the prevailing epidemiological transition in sub-Saharan Africa, the risk factors and ensuing complications of AF have changed and are on the increase. METHODS: This was a descriptive cross-sectional study involving 102 patients presenting with AF who were recruited from the cardiology unit of Mulago National Referral Hospital, Uganda, over 3 months...
2016: International Journal of General Medicine
https://www.readbyqxmd.com/read/27252564/county-health-factors-associated-with-avoidable-deaths-from-cardiovascular-disease-in-the-united-states-2006-2010
#18
Sophia Greer, Linda J Schieb, Matthew Ritchey, Mary George, Michele Casper
OBJECTIVE: Many cardiovascular deaths can be avoided through primary prevention to address cardiovascular disease (CVD) risk factors or better access to quality medical care. In this cross-sectional study, we examined the relationship between four county-level health factors and rates of avoidable death from CVD during 2006-2010. METHODS: We defined avoidable deaths from CVD as deaths among U.S. residents younger than 75 years of age caused by the following underlying conditions, using International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) codes: ischemic heart disease (I20-I25), chronic rheumatic heart disease (I05-I09), hypertensive disease (I10-I15), or cerebrovascular disease (I60-I69)...
May 2016: Public Health Reports
https://www.readbyqxmd.com/read/27203400/an-epidemiological-study-to-assess-the-true-incidence-and-prevalence-of-rheumatic-heart-disease-and-acute-rheumatic-fever-in-new-caledonian-school-children
#19
Philippe Corsenac, Rachel C Heenan, Adam Roth, Bernard Rouchon, Nina Guillot, Damian Hoy
AIM: To provide in New Caledonian school children (i) the prevalence of rheumatic heart disease (RHD) detected by annual screening program using new World Heart Federation diagnostic criteria; (ii) the point prevalence of acute rheumatic fever (ARF); and (iii) to investigate socio-demographic risk factors associated with RHD. METHODS: This study linked data from national ARF/RHD programs by combining ARF incidence data from the register with RHD prevalence data from echocardiographic screening data for a single age year of the population for overall point prevalence ARF/RHD rates...
July 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/27118427/association-study-of-inflammatory-genes-with-rheumatic-heart-disease-in-north-indian-population-a-multi-analytical-approach
#20
Usha Gupta, Snober S Mir, Naveen Garg, Surendra K Agarwal, Shantanu Pande, Balraj Mittal
Rheumatic heart disease (RHD) is an inflammatory, autoimmune disease; occurring as a consequence of group A streptococcal infection complicated by rheumatic fever (RF). An inappropriate immune response is the central signature tune to the complex pathogenesis of RHD. However, some of those infected develop RHD, and genetic host susceptibility factors are thought to play a key role in diseasedevelopment. Therefore, the present study was designed to explore the role of genetic variants in inflammatory genes in conferring risk of RHD...
June 2016: Immunology Letters
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