Paul Wurzer, Ludwik K Branski, Robert P Clayton, Gabriel Hundeshagen, Abigail A Forbes, Charles D Voigt, Clark R Andersen, Lars-P Kamolz, Lee C Woodson, Oscar E Suman, Celeste C Finnerty, David N Herndon
PURPOSE: The aim of this study was to quantify the effect of propranolol on hemodynamic parameters assessed using the PiCCO system in burned children. METHODS: We analyzed hemodynamic data from patients who were randomized to receive either propranolol (4 mg/kg/day) or placebo (control), which was initiated as a prospective randomized controlled trial. Endpoints were cardiac index (CI), percent predicted heart rate (%HR), mean arterial pressure (MAP), percent predicted stroke volume (%SV), rate pressure product (RPP), cardiac work (CW), systemic vascular resistance index (SVRI), extravascular lung water index (EVLWI), arterial blood gases, events of lactic acidosis, and mortality...
November 2016: Shock