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https://www.readbyqxmd.com/read/29765510/correlation-between-metabolic-syndrome-and-sleep-apnea
#1
REVIEW
Alejandro Castaneda, Edgar Jauregui-Maldonado, Iqbal Ratnani, Joseph Varon, Salim Surani
The so-called "metabolic syndrome" (MS), constitutes a cluster of metabolic and cardiovascular abnormalities, including fasting glucose, blood pressure, triglycerides, high density lipoprotein cholesterol (HDL-C), and waist circumference that arise from insulin resistance. Obstructive sleep apnea (OSA) syndrome is characterized by recurrent episodes of partial or complete obstruction of the upper airway, involving cessation or significant decreased airflow, with intermittent hypoxemia, frequent arousals from sleep and recurrent oxyhemoglobin desaturations that interfere with normal sleep patterns generating difficulty falling asleep, unrefreshing sleep and loud snoring...
April 15, 2018: World Journal of Diabetes
https://www.readbyqxmd.com/read/29758115/antepartum-care-of-women-who-are-obese-during-pregnancy-systematic-review-of-the-current-evidence
#2
REVIEW
Nicole S Carlson, Sharon Lynn Leslie, Alexis Dunn
INTRODUCTION: Nearly 40% of US women of childbearing age are obese. Obesity during pregnancy is associated with multiple risks for both the woman and fetus, yet clinicians often feel unprepared to provide optimal antepartum care for this group of women. We collected and reviewed current evidence concerning antepartum care of women who are obese during pregnancy. METHODS: We conducted a systematic review using PRISMA guidelines. Current evidence relating to the pregnancy care of women with a prepregnancy body mass index of 30kg/m2 or higher was identified using MEDLINE databases via PubMed, Embase, and Web of Science Core Collection between January 2012 and February 2018...
May 14, 2018: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29756059/pre-selection-of-primary-intubation-technique-is-associated-with-a-low-incidence-of-difficult-intubation-in-patients-with-a-bmi-of-35-kg-m-2-or-higher
#3
Tiberiu Ezri, Ronen Waintrob, Yuri Avelansky, Alexander Izakson, Katia Dayan, Mordechai Shimonov
Background: The incidence of difficult intubation (DI) in obese patients may reach a two-digit figure. No studies have assessed the effect of primary use of special intubation devices on lowering the incidence of DI. We assessed the effect of primary selection of special intubation techniques on the incidence of DI in patients with a BMI of 35 kg/m2 or higher. Patients and methods: Data from 546 patients with a BMI of 35 kg/m2 or higher who underwent bariatric surgery at Wolfson Medical Center from 2010 through 2014 was retrospectively extracted and analyzed for demographics, predictors of DI and intubation techniques employed...
April 2018: Romanian Journal of Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29755810/evaluation-of-traffic-accident-risk-in-in-city-bus-drivers-the-use-of-berlin-questionnaire
#4
Mehmet Sezai Taşbakan, Pervin Korkmaz Ekren, Funda Elmas Uysal, Özen K Başoğlu
OBJECTIVES: Traffic accidents associated with high mortality rate may produce serious problems especially in highways. Obstructive sleep apnea (OSA) has been associated with a high risk for traffic accidents due to excessive daytime sleepiness even in in-city drivers. In the present study, it was aimed to evaluate the rate of OSA symptoms and to identify risk factors associated with traffic accidents in in-city bus drivers. MATERIAL AND METHODS: A self-administered questionnaire including demographic and anthropometric features, sleep and work schedules, Berlin questionnaire, Epworth sleepiness score (ESS), and history of traffic accidents was used...
April 2018: Turkish Thoracic Journal
https://www.readbyqxmd.com/read/29752170/treating-obstructive-sleep-apnea-and-chronic-intermittent-hypoxia-improves-the-severity-of-nonalcoholic-fatty-liver-disease-in-children
#5
Shikha S Sundaram, Ann C Halbower, Jelena Klawitter, Zhaoxing Pan, Kristen Robbins, Kelley E Capocelli, Ronald J Sokol
OBJECTIVE: To determine the effects of treating obstructive sleep apnea/nocturnal hypoxia on pediatric nonalcoholic fatty liver disease (NAFLD) severity and oxidative stress. STUDY DESIGN: Biopsy proven participants (n = 9) with NAFLD and obstructive sleep apnea/hypoxia were studied before and after treatment with continuous positive airway pressure (CPAP) for sleep disordered breathing, including laboratory testing and markers of oxidative stress, urine F(2)-isoprostanes...
May 8, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29735001/obstructive-sleep-apnea-in-community-members-exposed-to-world-trade-center-dust-and-fumes
#6
Shilpi Ahuja, Zhaoyin Zhu, Yongzhao Shao, Kenneth I Berger, Joan Reibman, Omer Ahmed
STUDY OBJECTIVES: A relationship between obstructive sleep apnea (OSA) and exposure to the World Trade Center (WTC) dust and fumes has been suggested in responders but little is known about a possible relationship in community members. We characterized sleep studies performed in community members with WTC dust exposure to improve our understanding of the relationship between the diagnosis and severity of OSA and WTC dust exposure in this population. METHODS: Single-center, retrospective study of patients enrolled in a clinical treatment program for community members with WTC dust exposure...
April 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29734986/prevalence-associated-clinical-features-and-impact-on-continuous-positive-airway-pressure-use-of-a-low-respiratory-arousal-threshold-among-male-united-states-veterans-with-obstructive-sleep-apnea
#7
Andrey Zinchuk, Bradley A Edwards, Sangchoon Jeon, Brian B Koo, John Concato, Scott Sands, Andrew Wellman, Henry K Yaggi
STUDY OBJECTIVES: Determine the prevalence of, and clinical features associated with, a low respiratory arousal threshold (ArTH) among patients with obstructive sleep apnea (OSA), and to assess whether a low ArTH is associated with reduced long-term CPAP use. METHODS: Cross-sectional and longitudinal analyses were performed in an observational study conducted among 940 male veterans with OSA. Data for clinical characteristics, polysomnography characteristics, and long-term (5 ± 2 years) CPAP use were obtained from clinical records...
April 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29734985/clinical-reproducibility-of-the-epworth-sleepiness-scale-for-patients-with-suspected-sleep-apnea
#8
Angela J Campbell, Alister M Neill, Daniel A R Scott
STUDY OBJECTIVES: To determine the reproducibility of the Epworth Sleepiness Scale (ESS) score in a clinical population referred for diagnostic testing with suspected obstructive sleep apnea. METHODS: A retrospective audit of patients referred for a diagnostic sleep study with suspected sleep apnea was undertaken. Data collection was two 3-month time periods from January to March in 2012 and 2014. To evaluate reproducibility, the ESS score at primary care referral was compared to the ESS score at first specialist assessment/sleep assessment...
April 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29730042/clinical-and-polysomnographic-predictors-of-laryngopharyngeal-reflux-in-obstructive-sleep-apnea-syndrome
#9
Fábio Azevedo Caparroz, Milena de Almeida Torres Campanholo, Caroline Gomez Regina, Sung Woo Park, Leonardo Haddad, Luís Carlos Gregório, Fernanda Louise Martinho Haddad
INTRODUCTION: Obstructive sleep apnea syndrome and laryngopharyngeal reflux are diseases with a high prevalence in the overall population; however, it remains unclear whether they are diseases with the same risk factors present in the same populations or if there is any association between them. OBJECTIVES: To evaluate and determine the prevalence of laryngopharyngeal reflux in patients with moderate and severe obstructive apnea syndrome and also to determine its predictive factors...
April 14, 2018: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29703506/safety-and-short-term-outcomes-of-laparoscopic-sleeve-gastrectomy-for-patients-over-65-years-old-with-severe-obesity
#10
Panagiotis Lainas, Carmelisa Dammaro, Martin Gaillard, Gianfranco Donatelli, Hadrien Tranchart, Ibrahim Dagher
BACKGROUND: Laparoscopic sleeve gastrectomy (LSG) is a widely accepted, stand-alone bariatric operation. Data on elderly patients undergoing LSG are scarce. OBJECTIVES: The aim of this study was to demonstrate that LSG is safe and effective for patients>65 years old with severe obesity. SETTING: Department of Minimally Invasive Digestive Surgery, Antoine-Beclere Hospital, AP-HP, Paris-Saclay University, France. METHODS: Prospectively collected data from consecutive patients undergoing LSG were retrospectively analyzed...
March 8, 2018: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29695811/associations-of-obstructive-sleep-apnea-with-truncal-skeletal-muscle-mass-and-density
#11
Takeshi Matsumoto, Kiminobu Tanizawa, Ryo Tachikawa, Kimihiko Murase, Takuma Minami, Morito Inouchi, Tomohiro Handa, Toru Oga, Toyohiro Hirai, Kazuo Chin
Sarcopenia has been associated with several conditions relevant to obstructive sleep apnea (OSA), such as aging and obesity, but a direct relationship between OSA and skeletal muscle alterations has not been identified. This study investigated associations between computed tomography (CT)-measured skeletal muscle indices and OSA severity. Analyzed were 334 patients who underwent polysomnography to diagnose OSA. Lumbar skeletal muscles were assessed with CT for the skeletal muscle mass index (SMI, cross-sectional area, normalized for height squared) and skeletal muscle density (SMD, fat infiltration)...
April 25, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29691799/the-discriminative-power-of-stop-bang-as-a-screening-tool-for-suspected-obstructive-sleep-apnea-in-clinically-referred-patients-considering-gender-differences
#12
Jin Mou, Bethann M Pflugeisen, Brian A Crick, Paul J Amoroso, Kirk T Harmon, Stephen F Tarnoczy, S Shirley Ho, Kimberly A Mebust
PURPOSE: Obstructive sleep apnea (OSA) is the most commonly seen clinical sleep disorder. STOP-Bang, a widely used screening tool, yields a composite score based on eight dichotomized items including male gender. This study was designed to validate STOP-Bang among clinically referred patients and tested alternative scoring designs on tool performance, with a focus on gender differences in OSA. METHOD: STOP-Bang was administered to 403 female and 532 male subjects, followed by comprehensive sleep evaluation that included measurement of apnea-hypopnea indexes...
April 24, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29690686/-impaired-hypoxic-ventilatory-response-and-related-factors-in-han-and-uygur-patients-with-obstructive-sleep-apnea-hypopnea-syndrome
#13
Z M He, H Guo, X L Jiang, J P Li, Q L Zhang, Y P Yang, X S Dong, Piliqing Da, J Shi, M Li, M C Shi, F Han
Objective: To investigate the respiratory central hypoxia response and its related factors in Han and Uygur patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Methods: One hundred and sixty six OSAHS patients were selected from Jan. 2016 to Dec. 2016 in Department of Respiratory and Critical Care Medicine, Kelamayi Central Hospital, including 69 cases of Han nationality and 97 cases of Uygur nationality. Seventy-three healthy subjects of Uygur nationality were enrolled as the control group. All of them under went sleep monitoring, nocturnal oxygen saturation (SaO(2)), pulmonary function and respiratory central hypoxia response...
April 12, 2018: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29688821/risk-of-postoperative-complications-in-patients-with-obstructive-sleep-apnea-following-skull-base-surgery
#14
Phillip Huyett, Ryan J Soose, Amy E Schell, Juan C Fernandez-Miranda, Paul A Gardner, Carl H Snyderman, Eric W Wang
Objectives Obstructive sleep apnea (OSA) presents several challenges in skull base surgery, including increased intracranial pressure, worsened OSA with nasal packing, and avoidance of positive airway pressure (PAP) therapy postoperatively. The objective of this study was to examine the risk of postoperative complications in a skull base population with OSA in which PAP therapy is withheld. Study Design Retrospective cohort study. Setting Tertiary care hospital. Subjects and Methods Medical records of 414 adult patients undergoing anterior skull base procedures between January 1, 2014, and January 7, 2017, were retrospectively reviewed...
April 1, 2018: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29684667/demographics-and-socioeconomic-status-as-predictors-of-weight-loss-after-laparoscopic-sleeve-gastrectomy-a-prospective-cohort-study
#15
Amani Jambhekar, Amy Maselli, Shawn Robinson, Krystyna Kabata, Piotr Gorecki
BACKGROUND: Prior studies have established that race and socioeconomic factors may influence weight loss after bariatric surgery. Few studies have focused on laparoscopic sleeve gastrectomy (LSG). The objective of this study is to determine if demographic factors may predict postoperative weight loss following LSG. METHODS: Prospectively collected data on 713 consecutive primary LSG operations performed with the same technique between February 2010 and May 2016 by a single surgeon (PG) were analyzed...
April 20, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29684316/continuous-positive-airway-pressure-adherence-predictors-in-a-randomized-controlled-trial-enriched-with-women-and-minorities
#16
Anna M May, Tarek Gharibeh, Lu Wang, Amanda Hurley, Harneet Walia, Kingman P Strohl, Reena Mehra
BACKGROUND: Suboptimal continuous positive airway pressure (CPAP) adherence in obstructive sleep apnea (OSA) clinical trials involving predominantly Caucasian males limits interpretability and generalizability. We examined predictors of CPAP adherence in a clinical trial enriched with minorities. METHODS: The Sleep Apnea Stress Study - a randomized double-blind, sham-controlled trial of moderate-severe OSA patients - included participants with complete 8-week adherence data (n=138)...
April 20, 2018: Chest
https://www.readbyqxmd.com/read/29682848/the-stop-bang-questionnaire-shows-an-insufficient-specificity-for-detecting-obstructive-sleep-apnea-in-patients-with-atrial-fibrillation
#17
Asmaa M Abumuamar, Paul Dorian, David Newman, Colin M Shapiro
Obstructive sleep apnea (OSA) is a sleep disorder associated with significant cardiovascular comorbidities, including cardiac arrhythmia. The STOP-BANG questionnaire is an eight-item self-report questionnaire designed to screen patients for OSA and was validated in preoperative surgical patients. The STOP items are snoring, daytime tiredness, observed apneas and high blood pressure. The BANG items are body mass index >35 kg/m2 , age >50 years, neck circumference >40 cm and male gender. We aimed to determine the screening properties of the STOP-BANG questionnaire in patients with arrhythmia...
April 22, 2018: Journal of Sleep Research
https://www.readbyqxmd.com/read/29676929/the-role-of-upper-airway-morphology-in-apnea-versus-hypopnea-predominant-obstructive-sleep-apnea-patients-an-exploratory-study
#18
Tülay Özer, Adin Selcuk, Zahide Yılmaz, Nuray Voyvoda, İsa Çam, İsa Çam, Halil Erdem Ozel, Fatih Özdogan, Erkan Esen, Gülden Genç, Gulden Genc, Selahattin Genc
OBJECTIVES: The objective of this study was to investigate the association between upper airway morphology and apnea versus hypopnea predominance in patients with obstructive sleep apnea syndrome. METHODS: A retrospective study on consecutively computerized tomography scans obtained from 54 obstructive sleep apnea patients and 53 non-snoring controls. Computerized tomography scans were measured to evaluate upper airway and surrounding structures' morphologic characteristics...
April 20, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29671205/impact-of-continuous-positive-airway-pressure-on-vascular-endothelial-growth-factor-in-patients-with-obstructive-sleep-apnea-a-meta-analysis
#19
REVIEW
Jia-Chao Qi, LiangJi Zhang, Hao Li, Huixue Zeng, Yuming Ye, Tiezhu Wang, Qiyin Wu, Lida Chen, Qiaozhen Xu, Yifeng Zheng, Yaping Huang, Li Lin
PURPOSE: Cumulative evidence supports the clear relationship of obstructive sleep apnea (OSA) with cardiovascular disease (CVD). And, adherence to continuous positive airway pressure (CPAP) treatment alleviates the risk of CVD in subjects with OSA. Vascular endothelial growth factor (VEGF), a potent angiogenic cytokine regulated by hypoxia-inducible factor, stimulates the progression of CVD. Thus, whether treatment with CPAP can actually decrease VEGF in patients with OSA remains inconclusive...
April 18, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29664048/effect-of-rapid-eye-movement-sleep-behavior-disorder-on-obstructive-sleep-apnea-severity-and-cognition-of-parkinson-s-disease-patients
#20
Jun-Ying Huang, Jin-Ru Zhang, Yun Shen, Hui-Jun Zhang, Yu-Lan Cao, Cheng-Jie Mao, Ya-Ping Yang, Jing Chen, Chun-Feng Liu, Jie Li
Background: Rapid eye movement (REM) sleep behavior disorder (RBD) and obstructive sleep apnea (OSA) are the most common sleep disorders in Parkinson's disease (PD). The aim of this study was to identify whether RBD could alleviate OSA severity in PD patients and its effect on cognitive impairment. Methods: From February 2014 to May 2017, we recruited 174 PD patients from the Second Affiliated Hospital of Soochow University, all of whom underwent polysomnography (PSG)...
April 20, 2018: Chinese Medical Journal
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