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https://www.readbyqxmd.com/read/27919964/implementing-the-risk-of-ovarian-malignancy-algorithm-adding-obesity-as-a-predictive-factor
#1
Emanuela Anastasi, Danila Capoccia, Teresa Granato, Gianfranco Silecchia, Mario Rizzello, Maria Grazia Porpora, Luigi Frati, Antonio Angeloni, Frida Leonetti
AIM: To evaluate whether obesity represents a risk factor for the onset of ovarian cancer. PATIENTS AND METHODS: One hundred and sixty-three patients with a body mass index (BMI) >30 kg/m(2) (group 1) and 130 women with a BMI of <25 kg/m(2) (group 2) were included in the study. RESULTS: A Risk of Ovarian Malignancy Algorithm (ROMA) index above the cut-off (>13%) was found in 24.5% of group 1 patients, whereas a high ROMA score was identified in 5...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27876443/are-we-certain-about-which-measure-of-intolerance-of-uncertainty-to-use-yet
#2
Vincenzo G Roma, Debra A Hope
Intolerance of Uncertainty (IU) has been understood as a dispositional tendency to view the presence of negative events as unacceptable and threatening, regardless of the likelihood of those events occurring. The preference over the 12-item vs. 27-item of the IUS has been central to debate. The goals of the present study were to evaluate two competing models of measuring IU with model-fitting analyses and explore model invariance of gender (e.g. men vs. women). A sample of 980 individuals completed an online IUS survey...
November 23, 2016: Cognitive Behaviour Therapy
https://www.readbyqxmd.com/read/27847365/contribution-of-maternal-immunity-to-decreased-rotavirus-vaccine-performance-in-low-and-middle-income-countries
#3
Katayi Mwila, Roma Chilengi, Michelo Simuyandi, Sallie R Permar, Sylvia Becker-Dreps
The role of maternal immunity received by infants either transplacentally or orally from breast milk on rotavirus vaccine (RV) performance is evaluated. Breast feeding withholding has no effect on vaccine response, but higher levels of transplacental rotavirus-specific IgG antibody contribute to reduced vaccine seroconversion. The gaps in knowledge on the factors associated with low RV efficacy in low and middle income countries (LMIC) remain and further research is needed to shed more light on these issues...
November 9, 2016: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/27727032/the-roma-vaccination-gap-evidence-from-twelve-countries-in-central-and-south-east-europe
#4
Laetitia Duval, François-Charles Wolff, Martin McKee, Bayard Roberts
AIM: To investigate differences in vaccination coverage between Roma and otherwise comparable non-Roma children, including factors associated with the vaccination gap, health care access and discrimination faced by Roma. METHODS: We analyse data from the Roma Regional Survey 2011 implemented in twelve countries of Central and South-East Europe. Our sample comprises 8233 children aged up to 6 with 7072 Roma children and 1161 non-Roma children. Estimates of the Roma vaccination gap are estimated using Logit regressions...
October 7, 2016: Vaccine
https://www.readbyqxmd.com/read/27717696/falls-and-their-association-with-physical-tests-functional-capacity-clinical-and-demographic-factors-in-patients-with-rheumatoid-arthritis
#5
Mariana de Almeida Lourenço, Izabela Roma, Marcos Renato de Assis
OBJECTIVE: To evaluate the occurrence of falls reported by rheumatoid arthritis (RA) patients and its relation to disease activity, functional capacity and physical fitness. MATERIAL AND METHODS: A cross-sectional study constituted by a sample of 97 RA patients from the city of Marília (SP) from 2012 to 2013, were assessed for disease activity. Instruments validated for Brazilian population in order to evaluate physical and functional capacity were used. Data analysis was carried out with descriptive statistics, Spearman correlation and Chi-squared test, considering p<0...
September 22, 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/27694159/low-vaccination-coverage-of-greek-roma-children-amid-economic-crisis-national-survey-using-stratified-cluster-sampling
#6
Dimitris Papamichail, Ioanna Petraki, Chrisoula Arkoudis, Agis Terzidis, Emmanouil Smyrnakis, Alexis Benos, Takis Panagiotopoulos
BACKGROUND: Research on Roma health is fragmentary as major methodological obstacles often exist. Reliable estimates on vaccination coverage of Roma children at a national level and identification of risk factors for low coverage could play an instrumental role in developing evidence-based policies to promote vaccination in this marginalized population group. METHODS: We carried out a national vaccination coverage survey of Roma children. Thirty Roma settlements, stratified by geographical region and settlement type, were included; 7-10 children aged 24-77 months were selected from each settlement using systematic sampling...
October 2, 2016: European Journal of Public Health
https://www.readbyqxmd.com/read/27646618/quality-of-life-and-patient-satisfaction-with-family-practice-care-in-a-roma-population-with-chronic-conditions-in-northeast-slovenia
#7
Erika Zelko, Igor Švab, Danica Rotar Pavlič
OBJECTIVES: Health-related quality of life (HRQoL) measures a patient's subjective experience of his or her health status. We aimed to show how the presence of chronic diseases and satisfaction with family physicians (FPs) were associated with the HRQoL of a Roma population. METHODS: A cross-sectional study was carried out in May 2011 on a representative sample of 650 Roma living in Prekmurje, Slovenia. The EQ-5D questionnaire was used for measuring the HRQoL of the Roma...
March 2015: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/27644127/pre-and-postdiagnostic-diet-in-relation-to-mortality-among-breast-cancer-survivors-in-the-cps-ii-nutrition-cohort
#8
Marjorie L McCullough, Susan M Gapstur, Roma Shah, Peter T Campbell, Ying Wang, Colleen Doyle, Mia M Gaudet
PURPOSE: Due to the limited evidence on the role of diet and cause-specific mortality among breast cancer survivors, current nutrition guidelines for this population are consistent with those for cancer prevention. We evaluated whether diets consistent with the American Cancer Society recommendations for cancer prevention were associated with risk of death in breast cancer survivors. METHODS: Participants reported information on diet and other factors at baseline in 1992-1993 and twice during follow-up...
September 19, 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27629577/dietary-energy-density-and-postmenopausal-breast-cancer-incidence-in-the-cancer-prevention-study-ii-nutrition-cohort
#9
Terryl J Hartman, Susan M Gapstur, Mia M Gaudet, Roma Shah, W Dana Flanders, Ying Wang, Marjorie L McCullough
BACKGROUND: Dietary energy density (ED) is a measure of diet quality that estimates the amount of energy per unit of food (kilocalories per gram) consumed. Low-ED diets are generally high in fiber and fruits and vegetables and low in fat. Dietary ED has been positively associated with body mass index (BMI) and other risk factors for postmenopausal breast cancer. OBJECTIVE: We evaluated the associations of total dietary ED and energy-dense (high-ED) foods with postmenopausal breast cancer incidence...
October 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/27613936/high-prevalence-of-smoking-in-the-roma-population-seems-to-have-no-genetic-background
#10
Szilvia Fiatal, Réka Tóth, Ágota Moravcsik-Kornyicki, Zsigmond Kósa, János Sándor, Martin McKee, Róza Ádány
INTRODUCTION: The prevalence of smoking in Romani of both genders is significantly higher than in the general population. Our aim was to determine whether a genetic susceptibility contributes to the high prevalence of smoking among Roma in a study based on data collected from cross-sectional surveys. METHODS: Twenty single nucleotide polymorphisms known to be closely related to smoking behavior were investigated in DNA samples of Hungarian Roma (N = 1273) and general (N = 2388) populations...
December 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/27568335/comparison-of-the-effects-of-acute-and-chronic-administration-of-tetrahydroisoquinoline-amines-on-the-in-vivo-dopamine-release-a-microdialysis-study-in-the-rat-striatum
#11
Agnieszka Wąsik, Irena Romańska, Lucyna Antkiewicz-Michaluk
The etiology of Parkinson's disease (PD) may involve endogenous and exogenous factors. 1-Benzyl-1,2,3,4-tetrahydroisoquinoline (1BnTIQ), which was shown to be neurotoxic for dopaminergic neurons, is one of such factors, thus it can be used to construct an animal model of PD. In contrast, 1,2,3,4-tetrahydroisoquinoline (TIQ) and 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) produce neuroprotective effects acting as monoamino oxidase (MAO) inhibitors and free radical scavengers that reduce oxidative stress in the mammalian brain...
November 2016: Neurotoxicity Research
https://www.readbyqxmd.com/read/27499385/association-between-hepatitis-b-co-infection-and-elevated-liver-stiffness-among-hiv-infected-adults-in-lusaka-zambia
#12
Michael J Vinikoor, Lloyd Mulenga, Alice Siyunda, Kalo Musukuma, Roma Chilengi, Carolyn Bolton Moore, Benjamin H Chi, Mary-Ann Davies, Matthias Egger, Gilles Wandeler
OBJECTIVE: To describe liver disease epidemiology among HIV-infected individuals in Zambia. METHODS: We recruited HIV-infected adults (≥18 years) at antiretroviral therapy initiation at two facilities in Lusaka. Using vibration controlled transient elastography, we assessed liver stiffness, a surrogate for fibrosis/cirrhosis, and analysed liver stiffness measurements (LSM) according to established thresholds (>7.0 kPa for significant fibrosis and >11.0 kPa for cirrhosis)...
November 2016: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/27476084/safety-analysis-association-with-response-and-previous-treatments-of-everolimus-and-exemestane-in-181-metastatic-breast-cancer-patients-a-multicenter-italian-experience
#13
L Moscetti, P Vici, T Gamucci, C Natoli, E Cortesi, P Marchetti, D Santini, R Giuliani, I Sperduti, M Mauri, L Pizzuti, M L Mancini, M A Fabbri, V Magri, L Iezzi, V Sini, L D'Onofrio, L Mentuccia, A Vaccaro, S Ramponi, C L Roma, E M Ruggeri
PURPOSE: The everolimus and exemestane combination represents a treatment option for the endocrine sensitive metastatic breast cancer (MBC) patients. The toxicity profile reported in the Bolero 2 trial showed the feasibility in the selected patients. Few data are available for the unselected population. METHODS: In order to evaluate the safety in the unselected population of the clinical practice and to evaluate a possible association of toxicities with previous treatments, clinical data from 181 consecutive patients were retrospectively collected...
October 2016: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/27462596/analysis-of-falsely-elevated-risk-of-ovarian-malignancy-algorithm-in-women-with-ovarian-endometrioma
#14
Jae Jun Shin, Ye Ji Lee, Ranah Kim, Da Yong Lee, Kyu-Hee Won, Byung Chul Jee
OBJECTIVE: To estimate the incidence of falsely elevated risk of ovarian malignancy algorithm (ROMA) in a group of women with pathologically confirmed endometrioma and to investigate the associated factors. METHODS: One hundred premenopausal women surgically diagnosed with ovarian endometrioma were selected. Preoperative clinical, laboratory, and surgical characteristics were compared between the elevated-risk group (ROMA-premenopausal value, ≥7.4%) and normal-risk group (ROMA-premenopausal value, <7...
July 2016: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/27442406/influence-of-the-ethnic-affiliation-level-of-education-and-place-of-living-on-oral-health-at-geriatric-population-with-total-and-partial-dentures-in-republic-of-macedonia
#15
COMPARATIVE STUDY
Natasha Stavreva, Ljuben Guguvcevchi, Biljana Kapusevska
INTRODUCTION: Health is the main component of the quality of life, while oral health is component of the general health. The socio-demographic characteristics are one of the important factors for perception of the oral health and the quality of life. The main purpose of this study was to perform an evaluation of the quality of life of geriatric patients (older than 65) with built-in oral prosthetic dentures depending on the ethnic affiliation, level of education and place of living, as socio-demographic characteristics...
2015: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/27426308/diagnostic-performance-and-establishment-of-reference-limits-of-he4-in-korean-healthy-women
#16
Shinae Yu, Jin Kyung Lee, Jea-Hoon Kim, Hyosoon Park, Mi Yeon Lee, Seungho Ryu, Min-Jung Kwon, Hee-Yeon Woo
OBJECTIVE: We aimed to establish distribution and reference limits of HE4 and risk of ovarian malignancy algorithm (ROMA) in healthy Korean women and investigated the factors influencing HE4 levels. We also investigated the diagnostic performances of HE4 and ROMA score, compared with CA125. METHODS: We collected specimens from 1809 healthy Korean women, 140 specimens from patients with ovarian cancers (OCs) and 123 specimens from patients with benign ovarian tumor...
October 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27417144/assessment-of-cardiovascular-risk-factors-in-a-roma-community-from-southwestern-france
#17
Catherine Papon, Nicolas Delarche, Christophe Le Borgne, Frédéric Bauduer
OBJECTIVES: Roma from Central-Eastern Europe experience a reduced life expectancy in comparison with the general population. Predisposing cardiovascular risk factors could be the underlying reason for this. Here for the first time epidemiologic data on the distribution of cardiovascular risk factors in a subgroup of French Roma has been presented. METHODS: A descriptive epidemiological field survey was conducted in the Manouche community of Pau, Southwestern France...
July 15, 2016: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/27405445/intolerance-of-uncertainty-predicts-anxiety-outcomes-following-cbt-in-youth-with-asd
#18
Amy Keefer, Nicole L Kreiser, Vini Singh, Audrey Blakeley-Smith, Amie Duncan, Catherine Johnson, Laura Klinger, Allison Meyer, Judy Reaven, Roma A Vasa
Modified cognitive-behavioral therapy (MCBT) has been demonstrated to reduce anxiety in youth with autism spectrum disorder (ASD). However, non-response rates are fairly high. Few studies have investigated factors associated with response. Intolerance of uncertainty (IU) is a treatment target for anxiety and worry in neurotypical populations and has been linked to anxiety and ASD. We sought to examine whether IU affects outcomes following MCBT in 43 children, ages 8-14 years, with ASD without intellectual disability...
July 12, 2016: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/27354794/peptide-coated-gold-nanoparticles-for-modulation-of-angiogenesis-in-vivo
#19
Catarina Roma-Rodrigues, Amelie Heuer-Jungemann, Alexandra R Fernandes, Antonios G Kanaras, Pedro V Baptista
In this work, peptides designed to selectively interact with cellular receptors involved in the regulation of angiogenesis were anchored to oligo-ethylene glycol-capped gold nanoparticles (AuNPs) and used to evaluate the modulation of vascular development using an ex ovo chick chorioallantoic membrane assay. These nanoparticles alter the balance between naturally secreted pro- and antiangiogenic factors, under various biological conditions, without causing toxicity. Exposure of chorioallantoic membranes to AuNP-peptide activators of angiogenesis accelerated the formation of new arterioles when compared to scrambled peptide-coated nanoparticles...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27353588/monitoring-the-efficacy-of-antimalarial-medicines-in-india-via-sentinel-sites-outcomes-and-risk-factors-for-treatment-failure
#20
Neelima Mishra, Bina Srivastava, Ram Suresh Bharti, Roma Rana, Kamlesh Kaitholia, Anupkumar R Anvikar, Manoj Kumar Das, Susanta K Ghosh, Rajendra M Bhatt, Prajesh K Tyagi, Vas Dev, Sobhan Phookan, Suman Lata Wattal, Gagan Singh Sonal, Akshay Chand Dhariwal, Neena Valecha
BACKGROUND & OBJECTIVES: To combat the problem of antimalarial drug resistance, monitoring the changes in drug efficacy over time through periodic surveillance is essential. Since 2009, systematic and continuous monitoring is being done through nationwide sentinel site system. Potential early warning signs like partner drug resistance markers were also monitored in the clinical samples from the study areas. METHODS: A total of 1864 patients with acute uncomplicated malaria were enrolled in therapeutic efficacy studies of artesunate plus sulphadoxine-pyrimethamine (AS+SP) for Plasmodium falciparum; those infected with P...
April 2016: Journal of Vector Borne Diseases
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