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https://www.readbyqxmd.com/read/29150790/clinical-study-on-yishen-qufeng-shengshi-recipe-for-glomerular-proteinuria-patients-a-randomized-controlled-trial
#1
Qin Dai, Pei-Qing Zhang, Xiao-Qin Wang, Li-Fang Nie, Xiao-Jun Fu, Wen Peng, Yi Wang, Jun Li, Yue-Ping Bi, Xiu-Hua Mi, Min Yuan, Li-Qun He
OBJECTIVE: To explore the therapeutic effect of Yishen Qufeng Shengshi Recipe (, YQSR) in patients with glomerular proteinuria. METHODS: A total of 145 patients with glomerular proteinuria were selected and randomly assigned to the treatment group (108 cases) and the control group (37 cases) according to a random number table in a ratio of 3:1. All patients received conventional and symptomatic treatment. In addition, patients in the treatment and control groups were given YQSR (200 mL, twice per day, orally) and losartan (50 mg/d orally), respectively for 6 months...
November 17, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29148861/a-new-approach-for-determining-short-term-objective-prognostic-predictive-methods-for-terminal-cancer-patients-based-on-the-change-point-of-laboratory-test-values
#2
Kazuyuki Niki, Yoshiaki Okamoto, Yoshitaka Tabata, Mamiko Tsugane, Taizo Murata, Masao Mizuki, Yasushi Matsumura, Tatsuya Takagi, Etsuko Uejima
BACKGROUND: In terminal phase cancer, predicting a prognosis precisely plays an important role for patients and their families to live meaningful lives. However, there are no established short-term, objective prognostic predictive methods. OBJECTIVE: To develop simple, short-term, objective prognostic predictive methods through detecting a change point for laboratory test values. DESIGN: A retrospective chart review. SETTING/SUBJECTS: Subjects were cancer patients aged ≥16 years and discharged dead from Osaka University Hospital in 2008...
November 17, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29148625/evaluation-of-anabolic-steroid-induced-renal-damage-with-sonography-in-bodybuilders
#3
Umut H Kantarci, Zekine Punduk, Omer Senarslan, Alper Dirik
BACKGROUND: The aim of this study was to investigate the effect of anabolic steroids on kidneys in bodybuilders. METHODS: Twenty two bodybuilders were included in the study. Participants were divided into three groups according to the scheme of steroid usage: Group 1 (n=8, intramuscular 500 mg testosterone enanthate, intramuscular 400 mg nandrolone decanoate and oral 40 mg methandrostenolone for 12 weeks), Group 2 (n=7, intramuscular 500 mg testosterone enanthate, intramuscular 300 mg nandrolone decanoate and intramuscular 300 mg boldenone undecylenate for 16 weeks) and Group 3 (n=7, no steroid intake)...
November 17, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29147647/serum-albumin-is-independently-associated-with-persistent-organ-failure-in-acute-pancreatitis
#4
Wandong Hong, Suhan Lin, Maddalena Zippi, Wujun Geng, Simon Stock, Zarrin Basharat, Bicheng Cheng, Jingye Pan, Mengtao Zhou
Background and Aims: To investigate the association between serum albumin levels within 24 hrs of patient admission and the development of persistent organ failure in acute pancreatitis. Methods: A total of 700 patients with acute pancreatitis were enrolled. Multivariate logistic regression and subgroup analysis determined whether decreased albumin was independently associated with persistent organ failure and mortality. The diagnostic performance of serum albumin was evaluated by the area under Receiver Operating Characteristic (ROC) curves...
2017: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29147494/renoprotective-effect-of-crocin-following-liver-ischemia-reperfusion-injury-in-wistar-rats
#5
Seyyed Ali Mard, Ghaidafeh Akbari, Esrafil Mansouri, Mahdi Parsanahad
Objectives: The objectives of the current study were to evaluate the effects of hepatic ischemia/reperfusion (IR) injury on the activity of antioxidant enzymes, biochemical factors, and histopathological changes in rat kidney, and to investigate the effect of crocin on IR-related changes. Materials and Methods: Thirty-two male Wistar rats were randomly allocated into four groups (n=8). They were sham-operated, IR, crocin pre-treatment, and crocin pretreatment+IR groups...
October 2017: Iranian Journal of Basic Medical Sciences
https://www.readbyqxmd.com/read/29145491/the-urine-biomarker-panel-igfbp7-x-timp-2-nephrocheck%C3%A2-parameter-does-not-correlate-with-igfbp7-and-timp-2-gene-expression-in-urinary-sediment
#6
Daniela Knafl, Markus Müller, Sahra Pajenda, Zeynep Genc, Manfred Hecking, Ludwig Wagner
BACKGROUND: Acute kidney injury (AKI) is frequently observed in serious infections, following nephrotoxic medication, surgery and trauma. Here we tested whether the detection of two recently identified biomarkers for AKI, Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) and Insulin-Like Growth Factor Binding Protein 7 (IGFBP7), depends on the expression of these proteins in cells of the urinary sediment. METHOD: We collected urine samples of 33 kidney transplant recipients and 14 non-transplanted patients who all had AKI (stages 1-3 according to KDIGO), and measured [IGFBP7]x[TIMP-2] using the NephroCheck® Astute1 40 ™ meter...
2017: PloS One
https://www.readbyqxmd.com/read/29142958/diagnostic-performance-of-a-saliva-urea-nitrogen-dipstick-to-detect-kidney-disease-in-malawi
#7
Rhys Evans, Viviane Calice-Silva, Jochen G Raimann, Ulla Hemmila, Alison Craik, Mwayi Mtekateka, Fergus Hamilton, Zuze Kawale, Hamish Dobbie, Gavin Dreyer, Nathan Levin, Peter Kotanko, Roberto Pecoits-Filho
Introduction: Kidney disease (KD), including acute kidney injury, is common, severe and leads to significant mortality in the developing world. However, simple tools to facilitate diagnosis and guide treatment are lacking. We studied the diagnostic performance of saliva urea nitrogen (SUN) measured by dipstick to diagnose KD in a low-resource setting. Methods: Medical admissions to a tertiary hospital in Malawi had serum creatinine tested at presentation; SUN was measured using a dipstick...
March 2017: KI Reports
https://www.readbyqxmd.com/read/29142620/elevated-blood-urea-nitrogen-creatinine-ratio-is-associated-with-venous-thromboembolism-in-patients-with-acute-ischemic-stroke
#8
Hoon Kim, Kiwon Lee, Huimahn A Choi, Sophie Samuel, Jung Hyn Park, Kwang Wook Jo
Objective: Although venous thromboembolism (VTE) is frequently related to dehydration, the impact of dehydration on VTE in acute ischemic stroke (AIS) is not clear. This study investigated whether dehydration, as measured by blood urea nitrogen (BUN)/creatinine (Cr) ratio, influences the occurrence of VTE in patients with AIS. Methods: This is a retrospective study of patients with AIS between January 2012 and December 2013. Patients with newly diagnosed AIS who experienced prolonged hospitalization for at least 4 weeks were included in this study...
November 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29142379/dyspnea-eosinopenia-consolidation-acidemia-and-atrial-fibrillation-score-and-bap-65-score-tools-for-prediction-of-mortality-in-acute-exacerbations-of-chronic-obstructive-pulmonary-disease-a-comparative-pilot-study
#9
Viral Sangwan, Dhruva Chaudhry, Roopa Malik
Introduction: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) being common and often fatal, prognostic tools in AECOPD are lacking. Materials and Methods: A prospective, observational study was carried out in fifty patients of AECOPD admitted in A and E department. Dyspnea, Eosinopenia, Consolidation, Acidemia and atrial Fibrillation (DECAF) score and elevated blood urea nitrogen, altered mental status, pulse >109, age >65 (BAP-65) score were calculated...
October 2017: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29142148/seasonal-changes-in-serum-oxidative-stress-biomarkers-in-dairy-and-beef-cows-in-a-daytime-grazing-system
#10
Ahmad Nawid Mirzad, Takashi Tada, Hitoshi Ano, Ikuo Kobayashi, Takenori Yamauchi, Hiromu Katamoto
This study aims to evaluate the oxidative stress during hot summer season using serum oxidative stress biomarkers and elucidate the effects of serum antioxidant vitamin levels in dairy and beef cows in a daytime grazing system. Blood samples were collected once a month from eight Holstein Friesian (HF) and 10 Japanese Black (JB) cows from November 2013 to October 2014. Serum values of derivatives of reactive oxygen metabolites (d-ROMs) tended to be higher in March in both breeds and those in HF cows were kept at higher (P<0...
November 14, 2017: Journal of Veterinary Medical Science
https://www.readbyqxmd.com/read/29141361/-effect-of-probucol-on-preventing-contrast-induced-nephropathy-in-patients-undergoing-percutaneous-coronary-intervention
#11
X Q Suo, S C Yang, Z H Ma, T T Sun, W Y Zhang, H L Cong, W H Lin, C Z Lu, F S Tian, N K Fu
Objective: To investigate the preventive effect, possible mechanism and safety of probucol on contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI) in patients with coronary heart disease (CHD). Methods: A total of 641 patients with coronary heart disease were consecutively enrolled from Department of Cardiology, in Tianjin Chest Hospital, Tianjin TEDA International Cardiovascular Hospital, Tianjin First Central Hospital, Tianjin Fourth Central Hospital. They were randomly divided into probucol group (n=321) and control group (n=320)...
November 7, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29137911/effect-of-supplementing-a-diet-with-monensin-sodium-and-saccharomyces-cerevisiae-on-reproductive-performance-of-ghezel-ewes
#12
Leila Ahmadzadeh, Ali Hosseinkhani, Hossein Daghighkia
Effect of supplementing a diet, in an attempt to enhance reproduction, with monensin sodium and Saccharomyces cerevisiae yeast on reproductive performance was investigated during the breeding season using 44 Ghezel ewes (body weight 56.97±7.47kg, age 2-5 years and body condition score (BCS) 2.5) which were allocated randomly in equal numbers to the four dietary treatments as follows: 1) Basal diet plus supplemental feed (450g/ewe/d) plus monensin sodium (30mg/ewe/d) (MS); 2) Basal diet plus supplemental feed (450 g/ewe/d) plusSaccharomyces cerevisiae yeast (4×10(9)CFU/ewe/d) (SC); 3) Basal diet plus supplemental feed (450g/ewe/d) (FG); 4) Basal diet (only grazing on pasture, Control; G)...
November 11, 2017: Animal Reproduction Science
https://www.readbyqxmd.com/read/29130669/-a-preliminary-analysis-of-bifidobacterial-species-dependent-influence-on-the-health-of-the-elderly
#13
Shu-Yue Wang, Xiao-Hong Yu, Ming Li, Shan-Shan Li, Jun-Jie Miao, Qian Yu, Fang He
OBJECTIVE: To analyze the species dependent effect of bifidobacteria to the heath of the middle and elderly. METHODS: Total 148 healthy volunteers living in Chengdu with 5074 years old were recruited in 2015. The blood samples were collected from them and analyzed physiologically and immunologically. The fecal bifidobacterial were also analyzed by realtime fluorescence quantitative PCR (qPCR) using 16S rRNA targeting designed gene and species specific primers. RESULTS: Bifidobacterium can be detected in feces of the elderly,the detection rate was 100%,10⁸/g fecal...
September 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29128962/good-response-to-tolvaptan-shortens-hospitalization-in-patients-with-congestive-heart-failure
#14
Tomohito Kogure, Kentaro Jujo, Kazuyuki Hamada, Katsumi Saito, Nobuhisa Hagiwara
Tolvaptan has been gradually spread to use as a potent diuretic for congestive heart failure in the limited country. However, the response to this aquaretic drug still is unpredictable. A total of 92 patients urgently hospitalized due to congestive heart failure and treated with tolvaptan in addition to standard treatment was retrospectively analyzed. Responder of tolvaptan treatment was defined as a patient with peak negative fluid balance greater than 500 mL/day, and clinical profiles were compared between 76 responders and 16 non-responders...
November 11, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/29128910/allogeneic-ovarian-transplantation-using-immunomodulator-preimplantation-factor-pif-as-monotherapy-restored-ovarian-function-in-olive-baboon
#15
Michael Feichtinger, Eytan R Barnea, Atunga Nyachieo, Mats Brännström, S Samuel Kim
PURPOSE: Allogeneic ovarian transplantation may be an alternative in the future to oocyte donation in women with premature ovarian failure. The objectives of this study were to (a) evaluate allotransplantation feasibility for restoration of ovarian function and (b) assess efficacy of synthetic preimplantation factor (PIF) monotherapy as sole immune-acceptance regimen. METHODS: This is an experimental animal study using non-human primates (Papio anubis). Allogeneic orthotopic ovarian tissue transplantation was performed in two female olive baboons...
November 11, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29128808/attenuation-of-renal-damage-in-type-i-diabetic-rats-by-umbelliferone-a-coumarin-derivative
#16
Mayuresh S Garud, Yogesh A Kulkarni
BACKGROUND: It is well known that diabetes is one of the non-communicable disease affecting a large population worldwide. When diabetes remains untreated or uncontrolled, it leads to further serious complications, affecting vital organs like eyes, kidney, heart, etc. The present study was designed to evaluate effects of umbelliferone, a phytochemical, in treatment of diabetic nephropathy. METHODS: Experimental model used was streptozotocin (55mg/kg, ip) induced diabetic nephropathy in male Sprague Dawley rats...
June 27, 2017: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/29128213/the-effects-of-feeding-a-partial-mixed-ration-plus-a-top-dress-before-feeding-on-milk-production-and-the-daily-rhythm-of-feed-intake-and-plasma-hormones-and-metabolites-in-dairy-cows
#17
M Niu, K J Harvatine
Total mixed rations (TMR) are commonly fed to dairy cows with a goal of reducing ruminal acidosis, but the daily pattern of feed intake has major implication for rumen fermentation and postabsorptive physiology. Generally there is low feed intake during the overnight period and high intake after feeding and during the afternoon. The objective of this study was to determine if feeding a partial mixed ration (PMR) plus a high starch top-dress before feeding of the PMR would improve production and modify key daily rhythms...
November 8, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/29127993/molecular-prevalence-risk-factors-assessment-and-haemato-biochemical-alterations-in-hepatozoonosis-in-dogs-from-punjab-india
#18
Kaushlendra Singh, Harkirat Singh, Nirbhay Kumar Singh, Neeraj Kashyap, Naresh Kumar Sood, Shitanshu Shekar Rath
Hepatozoonosis caused by Hepatozoon canis is an important tick-borne disease of dogs in tropical and sub-tropical regions throughout the world. In the present study evaluation of blood samples collected from 225 dogs presented at Small Animal Clinics, GADVASU, Ludhiana, Punjab (India) was done for the presence of H. canis by PCR based assay targeting a portion of 18S rRNA gene. Of the total samples subjected to PCR, an amplicon of 666bp was detected in 13.78% samples whereas, routine blood smear examination revealed gamonts in 5...
December 2017: Comparative Immunology, Microbiology and Infectious Diseases
https://www.readbyqxmd.com/read/29127768/diabetic-ketoacidosis-hyperuricemia-and-encephalopathy-intractable-to-regular-dose-insulin
#19
Jillian Gregory, Sonali Basu
BACKGROUND: Diabetic ketoacidosis (DKA) in children less than 1 year of age is a rare occurrence. Typical presentation includes a prodrome of weight loss and polyuria with subsequent presentation to medical care when acidosis becomes symptomatic. CASE PRESENTATION: We describe an unusual case of a previously healthy infant with a 3 days' history of constipation, presenting acutely with abdominal pain, lethargy, and dehydration. On initial evaluation, our patient had profound encephalopathy, with marked tachypnea and work of breathing...
November 11, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29124925/organic-gas-sensor-with-an-improved-lifetime-for-detecting-breath-ammonia-in-hemodialysis-patients
#20
Ming-Yen Chuang, Chang-Chiang Chen, Hsiao-Wen Zan, Hsin-Fei Meng, Chia-Jung Lu
In this work, a TFB (poly[(9,9-dioctylfluorenyl-2,7-diyl)-co-(4,4'-(N-(4-s-butylphenyl)diphenylamine)]) sensor with a cylindrical nanopore structure exhibits a high sensitivity to ammonia in ppb-regime. The lifetime and sensitivity of the TFB sensor were studied and compared to those of P3HT (poly(3-hexylthiophene)), NPB (N,N'-di(1-naphthyl)-N,N'-diphenyl-(1,1'-biphenyl)-4,4'-diamine), and TAPC (4,4'-cyclohexylidenebis[N,N-bis(4-methylphenyl) benzenamine]) sensors with the same cylindrical nanopore structures...
November 17, 2017: ACS Sensors
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