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oral isotretinoin

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https://www.readbyqxmd.com/read/29760629/plane-warts-on-the-back-of-the-hand-successfully-treated-with-oral-isotretinoin
#1
Agnieszka Białecka, Kaja Męcińska-Jundziłł, Urszula Adamska, Adam Cichewicz, Marcin Białecki, Gerard Drewa, Rafał Czajkowski
No abstract text is available yet for this article.
April 2018: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/29729107/which-acne-treatment-has-the-best-influence-on-health-related-quality-of-life-literature-review-by-the-european-academy-of-dermatology-and-venereology-task-force-on-quality-of-life-and-patient-oriented-outcomes
#2
REVIEW
P V Chernyshov, L Tomas-Aragones, L Manolache, A Svensson, S E Marron, A W M Evers, V Bettoli, G B Jemec, J C Szepietowski
According to results of a recent literature search performed by the European Academy of Dermatology and Venereology (EADV) Task Forces (TF) on Quality of Life and Patient Oriented Outcomes (QoL and PO) and Acne, Rosacea and Hidradenitis Suppurativa (ARHS) most of publications where health-related (HR) QoL of acne patients was studied were clinical trials. Members of the EADV TF on QoL and PO decided to detect which acne treatment has the best influence on HRQoL of acne patients. A new literature search was organized to find publications on acne treatment where the HRQoL of patients was assessed as an outcome measure...
May 5, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29714807/-time-to-limit-the-use-of-antibiotics-in-rosacea
#3
Håkan Mobacken, Mats Berg, Eva Angesjö, Kari Dunér, Margareta Svensson, Ingrid Synnerstad
Rosacea is a chronic inflammatory disease with facial erythema and papulopustules. It is common in middle-aged/elderly persons and often affects self-perception and social well-being. It is generally classified into four subtypes. Improved understanding of pathophysiology has resulted in novel treatment approaches, but routine management in health care usually follows old trails. Most patients are managed in primary care. Greater attention to the reduced skin barrier, avoidance of exacerbating factors, better topicals and encouragement to topical maintenance treatment should reduce the use of oral tetracyclines...
April 24, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29706025/disseminated-filiform-hyperkeratosis-a-variant-of-porokeratosis
#4
A Kaushik, S Handa, D Chatterjee, V Keshavmurthy, R Mahajan
Filiform hyperkeratosis (FH) is a rare dermatosis with unresolved nosologic status, characterised by keratotic spicules in a predominant palmoplantar distribution1 . We report a case of disseminated filiform hyperkeratosis revealing a typical porokeratotic histology, and a successful therapeutic response to low dose oral isotretinoin. This article is protected by copyright. All rights reserved.
April 28, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29667796/isotretinoin-the-ups-are-just-as-troubling-as-the-downs
#5
Jay M Truitt, Jason S Reichenberg, Kevin G Sharghi, Shirlene M Sampson, Randall K Roenigk, Michelle Magid
INTRODUCTION: Isotretinoin, previously marketed as Accutane®, is an oral retinoid medication that is used to treat acne and other cutaneous disorders. Although the data is conflicting, previous reports suggest a causal relationship between isotretinoin and depression. When reviewing these previous reports, many patients who were diagnosed as 'depressed' did not undergo a thorough psychiatric evaluation and/or were not diagnosed according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders (DSM)...
April 18, 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29564872/reducing-the-oral-isotretinoin-skin-side-effects-efficacy-of-8-omega-ceramides-hydrophilic-sugars-5-niacinamide-cream-compound-in-acne-patients
#6
Maria V Cannizzaro, Annunziata Dattola, Virginia Garofalo, Ester Del Duca, Luca Bianchi
BACKGROUND: Acne vulgaris is a chronic inflammatory skin disease that manifests as open and closed comedones as well as inflammatory papules, pustules, and nodules localized on face and trunk. Oral isotretinoin demonstrated to be effective in controlling seborrhea, inflammation, Propionibacterium Acnes hyperproliferation and reducing scarring, nevertheless muco-cutaneous side effects, particularly dryness, itching, bruising are commonly seen in patients under treatment with isotretinoin reducing the compliance to the treatment...
April 2018: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29542350/pharmacotherapy-of-retinal-disease-with-visual-cycle-modulators
#7
Rehan M Hussain, Ninel Z Gregori, Thomas A Ciulla, Byron L Lam
Pharmacotherapy with visual cycle modulators (VCMs) is under investigation for retinitis pigmentosa (RP), Leber congenital amaurosis (LCA), Stargardt macular dystrophy (SMD) and nonexudative age-related macular degeneration (AMD), all blinding diseases that lack effective treatment options. Areas covered: The authors review investigational VCMs, including oral retinoids, 9-cis-retinyl-acetate (zuretinol) and 9-cis-β-carotene, which restore 11-cis-retinal levels in RP and LCA caused by LRAT and RPE65 gene mutations, and may improve visual acuity and visual fields...
March 15, 2018: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/29537444/efficacy-and-safety-of-adapalene-0-3-benzoyl-peroxide-2-5-gel-plus-oral-doxycycline-in-subjects-with-severe-inflammatory-acne-who-are-candidates-for-oral-isotretinoin
#8
James Q Del Rosso, Linda Stein Gold, Sandra Marchese Johnson, Maria Jose Rueda, Hilary Baldwin, Edward L Lain, Megan Landis, Marta Rendon, Emil Tanghetti, Jonathan Weiss
INTRODUCTION: Acne treatment guidelines suggest a combination approach with topical therapy including a topical retinoid, benzoyl peroxide and an oral antibiotic, or oral isotretinoin (OI), as first-line treatment options for severe acne vulgaris (AV). This study evaluated the efficacy and safety of a daily regimen of 0.3% adapalene and 2.5% benzoyl peroxide (0.3% A/BPO) gel and oral doxycycline 100 mg twice daily in severe (nonnodulocystic, non-conglobate) inflammatory AV. METHODS: This was a phase 4, 12-week, single-arm, openlabel, multi-center investigational study...
March 1, 2018: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/29488816/a-2017-update-challenging-the-cosmetic-procedural-delay-following-oral-isotretinoin-therapy
#9
Katherine Ann McDonald, Amanda Jane Shelley, Tadeusz Pierscianowski, Afsaneh Alavi
For decades it has been widely accepted that elective procedures should be delayed for at least 6-months following completion of isotretinoin therapy. However, numerous 2017 publications demonstrate the need for change in best practice. The evidence has yet to be succinctly summarized in a single article or in a stand-alone quick reference algorithm for physicians. This article's review of all 2017 publications confirms that the 6-month delay is not necessary for all procedures and provides a simple algorithmic approach to summarize the updated recommendations for procedural delay of cosmetic procedures following systemic isotretinoin therapy...
February 28, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29469597/treatment-of-multiple-eccrine-hidrocystoma-with-oral-isotretinoin-following-erbium-yttrium-aluminum-garnet-laser
#10
Serkan Demirkan
Eccrine hidrocystomes (EH) are benign cystic tumors of dermal eccrine ducts. There is still no gold standard treatment option for EH because of the large number of lesions, the risk of cicatrization and the different treatment options offered. We offer combined oral isotretinoin and following erbium-yttrium aluminum garnet laser treatment as an alternative treatment option in difficult patients with EH.
February 22, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29464980/evaluation-the-efficacy-of-trichloroacetic-acid-tca-33-in-treatment-of-oral-retinoid-induced-cheilitis-compared-with-placebo-vaseline-a-randomized-pilot-study
#11
Parvin Mansouri, Zahra Azizian, Somayeh Hejazi, Reza Chalangari, Katalin Martits Chalangari
BACKGROUND: Oral Isotretinoin (13-cis-retinoic acid) is a gold standardtreatment for severe forms of acne with cheilitis as a most frequent complication. We designed this novel study to investigate the therapeutic effect of trichloroacetic acid (TCA) 33% as compared with placebo to treat cheilitis. METHODS: In this pilot study, 90 acne vulgaris patients between 18 and 50 years, who referred dermatologic clinic with cheilitis, were assigned to either case (TCA) or control (Vaseline) group using permuted-block randomization from 2013 to 2015 with data analysis in 2016...
March 6, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29460332/vitamin-d-levels-in-acne-vulgaris-patients-treated-with-oral-isotretinoin
#12
Mohammed Abu El-Hamd, Moustafa A El Taieb, Hassan M Ibrahim, Sanaa S Aly
BACKGROUND/OBJECTIVES: Acne vulgaris is a common inflammatory skin disease. Vitamin D deficiency plays a role in many inflammatory skin diseases. It may play a role in pathogenesis of acne vulgaris. This study aimed to assess serum levels of 25 hydroxy vitamin D in patients with acne vulgaris before and after treatment with isotretinoin and its relation with acne vulgaris severity. METHODS: Ninety patients with acne vulgaris and 60 age-sex matched healthy subject as controls have been recruited in this study...
February 20, 2018: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29441308/granulomatous-periorificial-dermatitis-effectively-managed-with-oral-isotretinoin
#13
Swagata Tambe, Hemangi Jerajani, Poonam Pund
No abstract text is available yet for this article.
January 2018: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29417084/comparing-the-efficacy-of-low-dose-and-conventional-dose-of-oral-isotretinoin-in-treatment-of-moderate-and-severe-acne-vulgaris
#14
Gita Faghihi, Fatemeh Mokhtari, Nasrin Motamedi Fard, Narges Motamedi, Sayed Mohsen Hosseini
Objective: This study was conducted to compare the effect of low-dose isotretinoin with its conventional dose in patients with moderate and severe acne. Methods: This was a clinical trial conducted on 60 male and female patients with moderate and severe acne vulgaris. The patients were divided into two treatment groups: 0.5 mg/kg/day isotretinoin capsule and low-dose isotretinoin capsule (0.25 mg/kg/day). Patients in both groups received 6-month treatment. At the end of the 6th month and 12th month (6 months after the end of the treatment), they were examined again, and their improvement was determined and compared...
October 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/29403267/assessment-of-medication-adherence-and-responsible-use-of-isotretinoin-and-contraception-through-belgian-community-pharmacies-by-using-pharmacy-refill-data
#15
Natacha Biset, Mélanie Lelubre, Christelle Senterre, Karim Amighi, Olivier Bugnon, Marie P Schneider, Carine De Vriese
Purpose: The aims of the study were to evaluate medication adherence and the influencing factors for isotretinoin and contraception (oral, patches, and rings) and to evaluate the concomitant use of contraception and isotretinoin. Methods: Reimbursed prescription data from January 2012 to August 2015 of all patients in Belgium were received from Pharmanet-National Institute for Health and Disability Insurance. Medication adherence was measured according to the medication possession ratio...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29364446/morbihan-disease-a-therapeutic-challenge
#16
Fernanda Cabral, Lara Caroline Lubbe, Monisa Martins Nóbrega, Daniel Lago Obadia, Roberto Souto, Alexandre Carlos Gripp
Morbihan disease is a rare condition characterized by chronic and persistent erythematous solid edema localized on the face. It is believed to be a complication of rosacea and may occur at any stage of the disease. Features of this condition include variable therapeutic response and great refractoriness. We report a case of a 61-year-old man with rosacea history diagnosed with Morbihan disease, who showed excellent therapeutic response with the combination of deflazacort and oral isotretinoin but developed recurrence after corticosteroid discontinuation...
November 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29332721/oral-isotretinoin-as-an-adjunctive-treatment-for-recurrent-genital-warts
#17
Abhijeet Kumar Jha, Sidharth Sonthalia, Satyaki Ganguly
No abstract text is available yet for this article.
February 2018: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29313960/isotretinoin-treatment-for-folliculitis-decalvans-a-retrospective-case-series-study
#18
Berna Aksoy, Asli Hapa, Emine Mutlu
BACKGROUND: The literature includes only a few reports of oral isotretinoin for the treatment of folliculitis decalvans (FD). This study aimed to determine the most effective dose and duration of oral isotretinoin monotherapy for achieving remission in FD patients. METHODS: This retrospective case series study included FD patients that were treated with oral isotretinoin. Patient demographics, clinical characteristics, and treatment details were obtained from the patients' medical records...
February 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29285959/kyrle-s-disease-effectively-treated-with-oral-isotretinoin
#19
Martina Maurelli, Paolo Gisondi, Giampiero Girolomoni
BACKGROUND: Kyrle's disease (KD) is a primary perforating dermatosis that affects more commonly 30-50 year old females, and clinically characterized by pruritic hyperkeratotic and ulcerated nodules, papules and plaques, localized on extensor surface of upper and lower limbs, and on the trunk. OBJECTIVE: To determine the effectiveness of the treatment with oral isotretinoin in KD. METHODS: We present the case of a 63-year-old woman with hyperkeratotic, erythematous-brown nodules and plaques localized on arms and legs, intensely itching; some lesions were ulcerated and discharging...
January 10, 2018: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/29249250/-what-s-new-in-pediatric-dermatology
#20
C Chiaverini
The year 2017 in pediatric dermatology was marked by several consensus recommendations and meta analyzes on childhood psoriasis, atopic dermatitis or PHACE syndrome, case series on the role of anti-JAK treatment in adolescent with alopecia areata, sirolimus for vascular malformations, ivermectine for rosacea, inhibitors of MEK for type 1 neurofibromatosis or on the side effects of the oral isotretinoin for acne or propranolol for immature hemangioma. Only few randomized controlled studies have been published on the interest of adalimumab in the treatment of psoriasis or topical sirolimus for angiofibroma in tuberous sclerosis complex for example...
December 2017: Annales de Dermatologie et de Vénéréologie
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