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JOURNAL ARTICLE
Marilia Brito Gomes, Deborah Conte Santos, Karla Drummond, André Pinheiro, Luiza Harcar Muniz, Franz Leal, Carlos Antonio Negrato
AIMS: To determine the prevalence of overweight/obesity and its relationship with metabolic syndrome (MS), fatty liver index (FLI), cardiovascular risk factors (CVRF), and diabetes-related chronic complications (DRCC) in adult patients with type 1 diabetes (T1D). METHODS: This study was conducted in 14 Brazilian public clinics in ten cities, with 1,390 patients: 802 females (57.7%), 779 (56.0%) Caucasians, aged 33.6 ± 10.8 years, age at diagnosis, 16...
February 23, 2023: Diabetology & Metabolic Syndrome
#2
MULTICENTER STUDY
Marília B Gomes, Luis Eduardo Calliari, Deborah C Santos, Luiza H Muniz, Luis C Porto, Dayse A Silva, Carlos A Negrato
OBJECTIVE: To determine the influence of genomic ancestry (GA) and self-reportedcolor-race (SRCR) on glycemic control in adolescents with type 1 diabetes (T1D) in an admixed population. RESEARCH DESIGN AND METHODS: This multicenter nationwide study was conducted in 14 public clinics in 10 Brazilian cities. We estimated global and individual African, European, and Native Amerindian GA proportions using a panel of 46 AIM-INDEL markers. From 1760 patients, 367 were adolescents (20...
August 2020: Pediatric Diabetes
#3
JOURNAL ARTICLE
Fernando M A Giuffrida, Caroline Bulcão, Roberta A Cobas, Carlos Antonio Negrato, Marilia B Gomes, Sergio Atala Dib
BACKGROUND: Double diabetes (DD) describes both individuals with obesity upon diagnosis of type 1 diabetes and those who have gained weight during follow-up, although cardiovascular risk factors (CVRF) are not well understood in this group. We aim to evaluate the frequency of DD in a real-world type 1 diabetes sample and the interaction of insulin treatment with CVRF. METHODS: Multicentre cross-sectional study of 2711 individuals with clinical diagnosis of type 1 diabetes from secondary diabetes centres in 20 Brazilian cities...
2016: Diabetology & Metabolic Syndrome
#4
JOURNAL ARTICLE
Ana Carolina Contente Braga de Souza, João Soares Felício, Camila Cavalcante Koury, João Felício Abrahão Neto, Karem Barbosa Miléo, Flávia Marques Santos, Carlos Antonio Negrato, Ana Regina Bastos Motta, Denisson Dias Silva, Thaís Pontes Arbage, Carolina Tavares Carvalho, Hana Andrade de Rider Brito, Elizabeth Sumi Yamada, Franciane Trindade Cunha de Melo, Fabricio de Souza Resende, Juliana Cristina Cardoso Ferreira, Marilia Brito Gomes
BACKGROUND: Type 1 Diabetes Mellitus (Type 1 DM) affects the psychological and emotional well-being of patients and their families. This study aims to evaluate the health- related quality of life (HRQoL) of people with Type 1 DM in Brazil, a country of continental proportions, using the EuroQol questionnaires. METHODS: This was a retrospective, cross-sectional, multicenter study performed by the Brazilian Type 1 Diabetes Study Group, by analyzing EuroQol scores from 3,005 participants with Type 1 DM, in 28 public clinics in Brazil...
December 24, 2015: Health and Quality of Life Outcomes
#5
JOURNAL ARTICLE
João Soares Felício, Ana Carolina Contente Braga de Souza, Camila Cavalcante Koury, João Felício Abrahão Neto, Karem Barbosa Miléo, Flávia Marques Santos, Ana Regina Bastos Motta, Denisson Dias Silva, Thaís Pontes Arbage, Carolina Tavares Carvalho, Hana Andrade de Rider Brito, Elizabeth Sumi Yamada, Roberta Arnoldi Cobas, Alessandra Matheus, Lucianne Tannus, Catia Cristina Sousa Palma, Leticia Japiassu, João Regis Ivar Carneiro, Melanie Rodacki, Lenita Zajdenverg, Neuza Braga Campos de Araújo, Marilena de Menezes Cordeiro, Jorge Luiz Luescher, Renata Szundy Berardo, Marcia Nery, Catarina Cani, Maria do Carmo Arruda Marques, Luiz Eduardo Calliari, Renata Maria de Noronha, Thais Della Manna, Roberta Savoldelli, Fernanda Garcia Penha, Milton Cesar Foss, Maria Cristina Foss-Freitas, Antonio Carlos Pires, Fernando Cesar Robles, Carlos Antonio Negrato, Maria de Fatima Guedes, Sergio Atala Dib, Patricia Dualib, Saulo Cavalcanti da Silva, Janice Sepúlveda, Emerson Sampaio, Rosangela Roginski Rea, Ana Cristina Ravazzani de Almeida Faria, Balduino Tschiedel, Suzana Lavigne, Gustavo Adolfo Cardozo, Mirela Azevedo, Luis Henrique Canani, Alessandra Teixeira Zucatti, Marisa Helena Cesar Coral, Daniela Aline Pereira, Luiz Antonio de Araujo, Hermelinda Cordeiro Pedrosa, Monica Tolentino, Flaviene Alves Prado, Nelson Rassi, Leticia Bretones de Araujo, Reine Marie Chaves Fonseca, Alexis Dourado Guedes, Odelisa Silva de Mattos, Manuel Faria, Rossana Azulay, Adriana Costa E Forti, Cristina Figueiredo Sampaio Façanha, Renan Montenegro Junior, Ana Paula Montenegro, Naira Horta Melo, Karla Freire Rezende, Alberto Ramos, Deborah Laredo Jezini, Marilia Brito Gomes
BACKGROUND: In type 1 diabetes mellitus (T1DM) management, enhancing health-related quality of life (HRQoL) is as important as good metabolic control and prevention of secondary complications. This study aims to evaluate possible regional differences in HRQoL, demographic features and clinical characteristics of patients with T1DM in Brazil, a country of continental proportions, as well as investigate which variables could influence the HRQoL of these individuals and contribute to these regional disparities...
2015: Diabetology & Metabolic Syndrome
#6
MULTICENTER STUDY
Marilia Brito Gomes, Carlos Antonio Negrato
BACKGROUND: There is scarcity of data concerning retirement and workforce loss exclusively in patients with type 1 diabetes. The aim of this study was to evaluate the prevalence, causes, and predictors of retirement in patients with type 1 diabetes in Brazil. METHODS: This was a multicenter cross-sectional study conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. Data were obtained from 3,180 patients aged 22 ± 11.7 years; 56...
May 12, 2015: BMC Public Health
#7
JOURNAL ARTICLE
Lucianne Righeti Monteiro Tannus, Karla Rezende Guerra Drummond, Eliete Leão da Silva Clemente, Maria de Fátima Bevilacqua da Matta, Marilia Brito Gomes
Cardiovascular disease (CVD) is the leading cause of mortality in patients with type 1 diabetes (T1D). The cardiovascular autonomic neuropathy (CAN), although considered as an independent risk factor for CVD, remains underdiagnosed. The aim of this paper was to determine the prevalence, predictors of CAN in patients with T1D and its association with other chronic complications of diabetes. Patients with T1D underwent a clinical-epidemiological survey, had blood and urinary samples collected, performed ophthalmoscopic and clinical neurological examination and cardiovascular reflex tests...
2014: Frontiers in Endocrinology
#8
MULTICENTER STUDY
M B Gomes, C A Negrato, L E P Calliari
AIMS: Determine the relationship between age at menarche, glycemic control and cardiovascular risk factors in patients with type 1 diabetes living in urban areas. METHODS: This was a multicenter cross-sectional study conducted in 20 cities in four Brazilian geographic regions. Data were obtained from 1527 female patients, 59.3% Caucasians, aged 25.1 ± 10.6 years. Diabetes duration was 11.4 ± 8.1 years. Age at menarche was stratified in four groups: 8-11 (group 1, early menarche), 12 (group 2), 13 (group 3) and 14-18 years (group 4, late menarche)...
January 2015: Diabetes Research and Clinical Practice
#9
MULTICENTER STUDY
Kariane A K Davison, Carlos A Negrato, Roberta Cobas, Alessandra Matheus, Lucianne Tannus, Catia S Palma, Leticia Japiassu, Joao R I Carneiro, Melanie Rodacki, Lenita Zajdenverg, Neuza B C Araújo, Marilena M Cordeiro, Jorge Luiz Luescher, Renata S Berardo, Marcia Nery, Catarina Cani, Maria do Carmo A Marques, Luiz Eduardo Calliari, Renata M Noronha, Thais D Manna, Roberta Savoldelli, Fernanda G Penha, Milton C Foss, Maria Cristina Foss-Freitas, Maria de Fatima Guedes, Sergio A Dib, Patricia Dualib, Saulo C Silva, Janice Sepúlveda, Emerson Sampaio, Rosangela R Rea, Ana Cristina R A Faria, Balduino Tschiedel, Suzana Lavigne, Gustavo A Cardozo, Antonio C Pires, Fernando C Robles, Mirela Azevedo, Luis Henrique Canani, Alessandra T Zucatti, Marisa H C Coral, Daniela A Pereira, Luiz Antonio Araujo, Hermelinda C Pedrosa, Monica Tolentino, Flaviene A Prado, Nelson Rassi, Leticia B Araujo, Reine M C Fonseca, Alexis D Guedes, Odelisa S Mattos, Manuel Faria, Rossana Azulay, Adriana C Forti, Cristina F S Façanha, Renan Montenegro, Ana Paula Montenegro, Naira H Melo, Karla F Rezende, Alberto Ramos, João S Felicio, Flavia M Santos, Deborah L Jezini, Marilia B Gomes
BACKGROUND: To determine the relationship between adherence to the diet reported by patients with type 1 diabetes under routine clinical care in Brazil, and demographic, socioeconomic status, glycemic control and cardiovascular risk factors. METHODS: This was a cross-sectional, multicenter study conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. The data was obtained from 3,180 patients, aged 22 ± 11.8 years (56.3% females, 57...
March 7, 2014: Nutrition Journal
#10
JOURNAL ARTICLE
Roberta Arnoldi Cobas, Marcos Bosi Ferraz, Alessandra Saldanha de Mattos Matheus, Lucianne Righeti Monteiro Tannus, Aline Tiemi Kano Silva, Luiz Antonio de Araujo, Carlos Antonio Negrato, Sérgio Atala Dib, Marilia Brito Gomes
BACKGROUND AND AIMS: Regional differences in the clinical care of Type 1 diabetes (T1D) in Brazil have been recently described. This study aimed to estimate the costs of T1D from the public health care system's perspective across the regions of Brazil and to determine the components that influence these costs. METHODS: This was a retrospective, cross-sectional and nationwide multicenter study conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities...
December 27, 2013: Diabetology & Metabolic Syndrome
#11
MULTICENTER STUDY
M B Gomes, L R M Tannus, R A Cobas, A S M Matheus, P Dualib, A T Zucatti, C Cani, A D Guedes, F M Santos, J Sepulveda, M Tolentino, M C Façanha, A C R A Faria, S Lavigne, A P Montenegro, M Rodacki, M de Fatima Guedes, R Szundy, M M Cordeiro, P T S Santos, C A Negrato
AIM: The aim of this study was to determine the relationship between the daily frequency of self-monitoring of blood glucose and glycaemic control, demographic and socio-economic status in patients with Type 1 diabetes under routine clinical care in Brazil. METHODS: This was a cross-sectional, multi-centre study conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. The data were obtained from 3176 patients, aged 22 ± 11...
October 2013: Diabetic Medicine: a Journal of the British Diabetic Association
#12
MULTICENTER STUDY
Fernando M A Giuffrida, Alexis D Guedes, Eloa R Rocco, Denise B Mory, Patricia Dualib, Odelisa S Matos, Reine M Chaves-Fonseca, Roberta A Cobas, Carlos Antonio Negrato, Marilia B Gomes, Sergio A Dib
BACKGROUND: Cardiovascular risk factors (CVRF) may cluster in type 1 diabetes, analogously to the metabolic syndrome described in type 2 diabetes. The threshold of HbA1c above which lipid variables start changing behavior is unclear. This study aims to 1) assess the behavior of dyslipidemia according to HbA1c values; 2) detect a threshold of HbA1c beyond which lipids start to change and 3) compare the clustering of lipids and other non-lipid CVRF among strata of HbA1c individuals with type 1 diabetes...
2012: Cardiovascular Diabetology
#13
JOURNAL ARTICLE
Fani Eta Korn Malerbi, Carlos Antonio Negrato, Marilia B Gomes
UNLABELLED: <AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To evaluate the impact of type 1 diabetes (T1D) on family functioning and child-rearing practices from parents' point of view, to assess parents' health-related quality of life and to explore the relations between psychosocial variables and diabetes care outcomes in youth with diabetes. METHODS: This research was part of the cross-sectional multicenter Brazilian Type 1 Diabetes Study, conducted between December 2008 and December 2010 in 28 public clinics of 20 cities across four Brazilian geographical regions...
November 22, 2012: Diabetology & Metabolic Syndrome
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