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https://www.readbyqxmd.com/read/28212414/decline-in-infection-related-morbidities-following-drug-mediated-reductions-in-the-intensity-of-schistosoma-infection-a-systematic-review-and-meta-analysis
#1
Gisele Andrade, David J Bertsch, Andrea Gazzinelli, Charles H King
BACKGROUND: Since 1984, WHO has endorsed drug treatment to reduce Schistosoma infection and its consequent morbidity. Cross-sectional studies suggest pre-treatment correlation between infection intensity and risk for Schistosoma-related pathology. However, evidence also suggests that post-treatment reduction in intensity may not reverse morbidity because some morbidities occur at all levels of infection, and some reflect permanent tissue damage. The aim of this project was to systematically review evidence on drug-based control of schistosomiasis and to develop a quantitative estimate of the impact of post-treatment reductions in infection intensity on prevalence of infection-associated morbidity...
February 17, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28207542/rifampicin-induced-disseminated-intravascular-coagulation-in-pulmonary-tuberculosis-treatment-a-case-report-and-literature-review
#2
Guo Chen, Jian-Qing He
RATIONALE: Disseminated intravascular coagulation (DIC) induced by daily rifampicin therapy is rare, especially the patient is absent of malignancy, severe infection, and prior exposure to rifampicin. PATIENT CONCERNS: We report a case of DIC induced by daily rifampicin treatment for pulmonary tuberculosis. A 22-year-old, previously healthy man received an anti-tuberculosis therapy consisting of isoniazid, rifampicin, ethambutol, and pyrazinamide on the daily dose recommended by the World Health Organization tuberculosis guidelines after a diagnosis of pulmonary tuberculosis...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28203107/clinical-validation-of-immunoglobulin-a-nephropathy-diagnosis-in-swedish-biopsy-registers
#3
Simon Jarrick, Sigrid Lundberg, Adina Welander, C Michael Fored, Jonas F Ludvigsson
AIMS: The aims of this study were to validate the diagnosis of IgA nephropathy (IgAN) in Swedish biopsy registers against patient charts and to describe the clinical characteristics of patients with a biopsy indicating IgAN. METHODS: This is a population-based cohort study. Out of 4,069 individuals with a renal biopsy consistent with IgAN (biopsies performed in 1974-2011), this study reviewed patient charts of a random subset of 127 individuals. Clinical and biopsy characteristics at the time of biopsy were evaluated, and positive predictive values (PPV) were calculated with 95% confidence intervals (CI)...
2017: Clinical Epidemiology
https://www.readbyqxmd.com/read/28188755/defining-the-prevalence-of-asymptomatic-microscopic-hematuria-among-women-with-symptomatic-pelvic-organ-prolapse-implications-for-recommending-subsequent-diagnostic-evaluation
#4
Brian J Linder, Stephen A Boorjian, Emanuel C Trabuco, John B Gebhart, John A Occhino
OBJECTIVE: To evaluate the prevalence of AMH in women presenting with POP, as well as the relationship of POP stage with AMH. MATERIALS AND METHODS: Charts of women evaluated in a Female Pelvic Medicine and Reconstructive Surgery clinic between January 2015 and July 2016 were retrospectively reviewed. The prevalence of AMH (≥3 rbc per hpf on one urinalysis) was compared for women with symptomatic POP and those with urinary incontinence (UI) without symptomatic POP...
February 7, 2017: Urology
https://www.readbyqxmd.com/read/28185760/why-we-need-a-higher-suspicion-index-of-urolithiasis-in-children
#5
REVIEW
Pierluigi Marzuillo, Stefano Guarino, Andrea Apicella, Angela La Manna, Cesare Polito
BACKGROUND: Most children with symptoms of urolithiasis and urinary solute excretion abnormalities leading to stone formation have no calculi revealed by ultrasound or X-ray plain film ("occult urolithiasis"). This covers a large group of children presenting with common symptoms such as abdominal pain, hematuria, and dysuria, often faced by general practitioners and pediatricians. However, half or more of children with urolithiasis could present with abdominal/flank pain without specific urinary symptoms...
January 29, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28174414/a-case-of-henoch-schonlein-purpura-associated-with-rotavirus-infection-in-an-elderly-asian-male-and-review-of-the-literature
#6
Chen Tang, Daphne Scaramangas-Plumley, Cynthia C Nast, Zab Mosenifar, Marc A Edelstein, Michael Weisman
BACKGROUND Henoch-Schönlein purpura (HSP), a small vessel vasculitis mediated by deposition of immune-complexes containing IgA in the skin, gut, and glomeruli, often presents with abdominal pain, purpuric rash in the lower extremities and buttocks, joint pain, and hematuria. The disease most commonly targets children but can affect adults who tend to have a worse prognosis. CASE REPORT We discuss a case of HSP in an elderly Chinese male who presented with severe proximal bowel inflammation, vasculitic rash, and proteinuria; he was found to have positive stool rotavirus and giardia...
February 8, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28152097/minimally-invasive-percutaneous-nephrolithotomy-improves-stone-free-rates-for-impacted-proximal-ureteral-stones-a-systematic-review-and-meta-analysis
#7
Zi-Ming Gao, Shan Gao, Hong-Chen Qu, Kai Li, Ning Li, Chun-Lai Liu, Xing-Wang Zhu, Yi-Li Liu, Ping Wang, Xiao-Hua Zheng
BACKGROUND: Urinary stones are common medical disorders and the treatment of impacted proximal ureteral stones (IPUS) is still a challenge for urologists. The aim of this study was to compare the efficacy and safety of minimally invasive percutaneous nephrolithotomy (MI-PCNL) and ureteroscopic lithotripsy (URL) in the treatment of IPUS via a meta-analysis. METHODS: We collected studies using PubMed, Embase, and Cochrane Library from 1978 to November 2016 and analyzed them using Stata 12...
2017: PloS One
https://www.readbyqxmd.com/read/28127177/prognostic-benefit-of-surgical-management-of-renal-cell-carcinoma-invading-the-inferior-vena-cava
#8
REVIEW
Aikaterini Mastoraki, Sotiria Mastoraki, Maria Tsikala-Vafea, Ioannis S Papanikolaou, Andreas Lazaris, Vassilios Smyrniotis, Nikolaos Arkadopoulos
Renal cell carcinoma (RCC) accounts for approximately 3 % of adult malignancies and 90-95 % of neoplasms arising from the kidney. One of the unique features of RCC is the tumor thrombus formation that migrates into the venous system including renal vein (RV) and inferior vena cava (IVC). Only 10 % of patients with RCC present with the classic triad of flank pain, hematuria and defined mass, while 25-30 % of affected patients are asymptomatic. Signs of para-neoplastic syndrome such as hypercalcemia, hypertension, anemia, cachexia and increased erythrocyte sedimentation rate (ESR) are often apparent...
March 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28125986/clinical-analysis-of-small-cell-carcinoma-of-the-bladder-in-chinese-nine-case-reports-and-literature-reviews
#9
Zhi Chen, Qingquan Liu, Ruibao Chen, Zhuo Liu, Mingchao Li, Qing Ling, Licheng Wu, Jun Yang, Xiaming Liu, Tao Wang, Zhiquan Hu, Xiaoling Guo, Shaogang Wang, Weiming Yang, Jihong Liu
BACKGROUND: Small cell carcinoma of the bladder (SCCB) is a kind of rare and highly aggressive tumor that is present in an advanced stage and has a propensity for early metastasis. The main presenting symptom of SCCB is hematuria. Surgery, chemotherapy, and radiotherapy, either alone or as a part of combined therapy, have been used as the treatment. The aim of this study is to present our experience with 9 SCCB patients who were treated with different modalities and to share the findings upon reviewing the literatures for patients with SCCB reported in 56 literatures in Chinese...
January 26, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28123739/urachal-carcinoma-report-of-two-cases-and-review-of-the-literature
#10
Jing Quan, Xiang Pan, Lu Jin, Tao He, Jia Hu, Bentao Shi, Jian Peng, Zhebo Chen, Shangqi Yang, Xiangming Mao, Yongqing Lai
Urachal carcinoma is a rare tumor that most commonly occurs in ovaries and less often in the adnexal region and urinary system. We herein present two cases of urachal carcinoma: One case was a 32-year-old male patient who presented with painless hematuria with blood clots for 1 month, whereas the other case was a 50-year-old woman who presented with gross hematuria with mild dysuria, urgency and frequent urination for 1 year. Following surgical resection, the two patients were diagnosed with urachal adenocarcinoma (mixed type) and urachal mucinous adenocarcinoma, respectively, based on the histopathological examination...
January 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28116915/non-visible-asymptomatic-haematuria-a-review-of-the-guidelines-from-the-urologist-s-perspective
#11
Petros Sountoulides, Ioannis Mykoniatis, Linda Metaxa
Non-visible hematuria, also referred to as 'microscopic hematuria' or 'dipstick positive hematuria' is a common reason for urology referrals with prevalence rates that range from 13% to 20%. The main concern for investigating non-visible hematuria, especially in the absence of lower urinary tract symptoms, is its potential relation to urinary tract malignancy, which however does not exceed 5%. The pathway of investigation of non-visible hematuria is impeded by the lack of clarity over definitions, diagnosis and specialist referral criteria...
January 27, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28101735/urethral-carcinoma-in-situ-recognition-and-management
#12
Ricardo H Berjeaut, Maliza D I Persaud, Nikolai Sopko, Arthur L Burnett
PURPOSE: Urethral carcinoma in situ (CIS) is an uncommon malignancy that is poorly described in the published literature and is often under-recognized in the clinical setting. This short case series reports some challenges associated with the recognition and management of this disease. METHODS: A retrospective chart review was done over a 12-year period of patients presenting with urethral cancer to the Johns Hopkins Hospital. Four patients were identified with CIS of the anterior urethra, and their demographic and clinical data were recorded...
January 18, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28068364/meta-analysis-of-stenting-versus-non-stenting-for-the-treatment-of-ureteral-stones
#13
Hai Wang, Libo Man, Guizhong Li, Guanglin Huang, Ning Liu, Jianwei Wang
BACKGROUND AND AIM: Ureteroscopic lithotripsy (URL) and extracorporeal shock wave lithotripsy (ESWL) are two widely used methods for the treatment of ureteral stones. The need for ureteral stenting during these procedures is controversial. In this meta-analysis, we evaluated the benefits and disadvantages of ureteral stents for the treatment of ureteral stones. METHODS: Databases including PubMed, Embase and Cochrane library were selected for systematic review of randomized controlled trials (RCTs) comparing outcomes with or without stenting during URL and ESWL...
2017: PloS One
https://www.readbyqxmd.com/read/28040229/-macroscopic-hematuria-secondary-to-nutcracker-syndrome-and-successful-endovascular-treatment
#14
Carlos A Hinojosa, Javier E Anaya-Ayala, Estefanía Boyer-Duck, Hugo Laparra-Escareno, Adriana Torres-Machorro, Rene Lizola
BACKGROUND: Nutcracker syndrome is a rare entity, and in the majority of cases is the result of extrinsic compression of the left renal vein between the superior mesenteric artery and the aorta, associated with functional stenosis. OBJECTIVE: To present the case of a 19-year-old female with no significant medical history with confirmed diagnosed of nutcracker syndrome treated successfully by endovascular means. CLINICAL CASE: She was referred to the Vascular Surgery Department with a 6-month history of macroscopic haematuria, after other aetiologies were ruled out...
December 28, 2016: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/28031042/transitional-cell-carcinoma-with-extension-of-the-renal-vein-and-ivc-tumor-thrombus-report-of-three-cases-and-literature-review
#15
Mingyang Li, An Shi, Wen Kong, Jin Zhang, Yonghui Chen, Jiwei Huang, Yiran Huang
BACKGROUND: Transitional cell carcinoma (TCC) originating from the renal pelvis with a venous tumor thrombus is a rare entity. However, clinicians should be aware of it because of its high malignancy and poor prognosis. CASE PRESENTATION: Here, we report three cases of pathologically confirmed TCC originating from the renal pelvis with extension into the renal vein or inferior vena cava (IVC). Of these patients, two are males and one is female (58~73 years old)...
December 28, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27983969/clinical-and-laboratory-characteristics-epidemiology-and-outcomes-of-murine-typhus-a-systematic-review
#16
REVIEW
Constantinos Tsioutis, Maria Zafeiri, Asimakis Avramopoulos, Efthymia Prousali, Michael Miligkos, Spyridon A Karageorgos
Murine or endemic typhus, a febrile disease caused by Rickettsia typhi, is often misdiagnosed due to its non-specific presentation. We sought to evaluate all available evidence in the literature regarding the clinical and laboratory manifestations, epidemiological characteristics, and outcomes of murine typhus. Pubmed was searched for all articles providing available data. In an effort to incorporate contemporary data, only studies from 1980 were included. Thirty-three case series including 2074 patients were included in final analysis...
February 2017: Acta Tropica
https://www.readbyqxmd.com/read/27981926/stone-free-rate-after-extracorporeal-shockwave-lithotripsy-in-the-management-of-pediatric-renal-stones-in-lower-pole-and-other-locations-a-comparative-study
#17
Nadeem Iqbal, Shujah Muhammad, Warda Zafar, Ravale Tashfeen, Javaria Faiz, Aisha Hasan, Ijaz Hussain, Saeed Akhter
OBJECTIVE: To determine a difference in the stone-free-rate among different renal locations in children after extracorporeal shockwave lithotripsy (ESWL). STUDY DESIGN: A descriptive study. PLACE AND DURATION OF STUDY: Urology Department, Shifa International Hospital, Islamabad, Pakistan, from January 2007 to June 2015. METHODOLOGY: The study included children who underwent ESWL, divided into three groups based on location of stones in kidney as group A (lower pole stones), group B (upper and mid pole stones) and group C (renal pelvis stone), respectively...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27976566/ceftriaxone-induced-hemolytic-anemia-in-a-child-successfully-managed-with-intravenous-immunoglobulin
#18
Aysel Vehapoğlu, Nilüfer Göknar, Rümeysa Tuna, Fatma Betül Çakır
Drug-induced hemolytic anemia is an immune-mediated phenomenon that leads to the destruction of red blood cells. Here, we present a case of life-threatening ceftriaxone-induced hemolytic anemia (CIHA) in a previously healthy 3-year-old girl. We also reviewed the literature to summarize the clinical features and treatment of hemolytic anemia. Acute hemolysis is a rare side effect of ceftriaxone therapy associated with high mortality. Our patient had a sudden loss of consciousness with macroscopic hematuria and her hemoglobin dropped from 10...
2016: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27957427/a-rare-case-of-hematuria-primary-amyloidosis-of-the-bladder-neck
#19
Sotonye Tolofari, Asif Ansari, Ross J Knight
Primary and localized amyloidosis of the urinary tract is considered to be a rare clinical entity with approximately 160 cases documented in the literature. Here we present a case of a 77 year old gentleman with painless visible hematuria. Flexible cystoscopy revealed abnormal and polypoidal bladder mucosa. Transurethral resection of these lesions revealed histology with congo-red staining and positive green-apple birefringence, these findings are consistent with amyloidosis. There has so far been no sign of recurrence in this gentleman, with routine cystoscopic surveillance...
January 2017: Urology Case Reports
https://www.readbyqxmd.com/read/27921039/clinical-manifestation-and-management-of-adpkd-in-western-countries
#20
REVIEW
Claudia Sommerer, Martin Zeier
BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease in Western countries. The prevalence is between 2.4/10,000 and 3.9/10,000. ADPKD represents a systemic disease resulting in deterioration in renal function. Until now, mutations in two genes (PKD1 and PKD2) have been identified. Recently, the European Medicines Agency (EMA) approved the use of the vasopressin V2 receptor antagonist tolvaptan to slow the progression of cyst development and renal insufficiency connected with ADPKD in adult patients with chronic kidney disease stages 1-3 at initiation of treatment with evidence of rapidly progressing disease...
October 2016: Kidney Diseases
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