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https://www.readbyqxmd.com/read/29620563/comparison-of-ipsilateral-and-contralateral-paramedian-forehead-flaps-to-reconstruct-lateral-nasal-subunits
#1
Adam R Mattox, Ashley McGuinness, Eric Armbrecht, Ian A Maher
No abstract text is available yet for this article.
April 3, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29502605/january-consultation-7
#2
Cynthia Mattox
No abstract text is available yet for this article.
January 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29389862/moving-the-plasmon-of-lab%C3%A2-from-ir-to-near-ir-via-eu-doping
#3
Tracy M Mattox, D Keith Coffman, Inwhan Roh, Christopher Sims, Jeffrey J Urban
Lanthanum hexaboride (LaB₆) has become a material of intense interest in recent years due to its low work function, thermal stability and intriguing optical properties. LaB₆ is also a semiconductor plasmonic material with the ability to support strong plasmon modes. Some of these modes uniquely stretch into the infrared, allowing the material to absorb around 1000 nm, which is of great interest to the window industry. It is well known that the plasmon of LaB₆ can be tuned by controlling particle size and shape...
February 1, 2018: Materials
https://www.readbyqxmd.com/read/29365360/drug-shortages-effect-on-parenteral-nutrition-therapy
#4
REVIEW
Beverly Holcombe, Todd W Mattox, Steve Plogsted
Drug shortages continue to be a threat to the health and welfare of numerous patients in the United States. For patients who depend on parenteral nutrition (PN) for survival, these shortages pose an even greater threat. Almost 75% of active drug shortages are sterile injectables, which includes PN components. Providing PN therapy is particularly challenging for clinicians because this is a complex medication and may contain 40 or more individual ingredients, of which multiple components may simultaneously be in limited supply...
February 2018: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/29348365/detection-and-localization-of-surgically-resectable-cancers-with-a-multi-analyte-blood-test
#5
Joshua D Cohen, Lu Li, Yuxuan Wang, Christopher Thoburn, Bahman Afsari, Ludmila Danilova, Christopher Douville, Ammar A Javed, Fay Wong, Austin Mattox, Ralph H Hruban, Christopher L Wolfgang, Michael G Goggins, Marco Dal Molin, Tian-Li Wang, Richard Roden, Alison P Klein, Janine Ptak, Lisa Dobbyn, Joy Schaefer, Natalie Silliman, Maria Popoli, Joshua T Vogelstein, James D Browne, Robert E Schoen, Randall E Brand, Jeanne Tie, Peter Gibbs, Hui-Li Wong, Aaron S Mansfield, Jin Jen, Samir M Hanash, Massimo Falconi, Peter J Allen, Shibin Zhou, Chetan Bettegowda, Luis A Diaz, Cristian Tomasetti, Kenneth W Kinzler, Bert Vogelstein, Anne Marie Lennon, Nickolas Papadopoulos
Earlier detection is key to reducing cancer deaths. Here, we describe a blood test that can detect eight common cancer types through assessment of the levels of circulating proteins and mutations in cell-free DNA. We applied this test, called CancerSEEK, to 1005 patients with nonmetastatic, clinically detected cancers of the ovary, liver, stomach, pancreas, esophagus, colorectum, lung, or breast. CancerSEEK tests were positive in a median of 70% of the eight cancer types. The sensitivities ranged from 69 to 98% for the detection of five cancer types (ovary, liver, stomach, pancreas, and esophagus) for which there are no screening tests available for average-risk individuals...
February 23, 2018: Science
https://www.readbyqxmd.com/read/29336897/the-real-world-effect-of-intravitreous-anti-vascular-endothelial-growth-factor-drugs-on-intraocular-pressure-an-analysis-using-the-iris-registry
#6
Elizabeth A Atchison, Kevin M Wood, Cynthia G Mattox, Catherine N Barry, Flora Lum, Mathew W MacCumber
PURPOSE: To identify sustained differences in intraocular pressure (IOP) after intravitreous injections of anti-vascular endothelial growth factor (VEGF) drugs. DESIGN: Database study. PARTICIPANTS: Patients seeing an ophthalmic provider who contributes to the database. METHODS: We identified a total of 23 776 unique patients who received only a single type of anti-VEGF medication (bevacizumab, aflibercept, or ranibizumab) by injection in the right eye in the American Academy of Ophthalmology Intelligent Research in Sight Registry...
January 11, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29167902/trends-in-use-of-ambulatory-surgery-centers-for-cataract-surgery-in-the-united-states-2001-2014
#7
Brian C Stagg, Nidhi Talwar, Cynthia Mattox, Paul P Lee, Joshua D Stein
Importance: Cataract surgery is commonly performed at ambulatory surgery centers (ASCs) and hospital outpatient departments (HOPDs). These venues differ in many ways, including surgical efficiency, patient throughput, patient safety, and costs per surgery. Objective: To determine trends in use of ASCs and HOPDs for cataract surgery from 2001 to 2014 and factors affecting the site of surgery. Design, Setting, and Participants: This retrospective longitudinal cohort analysis involved individuals 40 years and older who underwent cataract surgery between January 2001 and December 2014 from a nationwide US managed care network...
January 1, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29037583/landmarks-for-the-preservation-of-the-middle-temporal-artery-during-mastoid-surgery-cadaveric-dissection-study
#8
Pedram Daraei, Douglas E Mattox
IMPORTANCE: The middle temporal artery flap is a vascularized periosteal flap that is highly useful for otologic reconstruction including the middle cranial fossa, mastoidectomy defect, and external auditory canal. The course of the artery is close to the external auditory canal and is easily injured during preliminary exposure and elevation of flaps. OBJECTIVES: To describe the course of the middle temporal artery in relation to the external auditory canal and the superficial temporal artery in order to enhance preservation and use in otologic reconstruction...
January 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28966197/reducing-risks-associated-with-negative-pressure-wound-therapy-strategies-for-clinical-practice
#9
Elizabeth Andersson Mattox
Negative-pressure wound therapy represents a relatively new strategy for wound management. Significant, life-threatening complications (bleeding, infection, and retained dressing material) have been associated with negative-pressure wound therapy. As a result, the Food and Drug Administration published several warnings to negative-pressure wound therapy users and recommended that clinicians ordering, managing, and/or monitoring negative-pressure wound therapy be aware of the potential complications and be prepared to take prompt action to reduce patients' risk for harm...
October 2017: Critical Care Nurse
https://www.readbyqxmd.com/read/28947422/pd-1-expression-in-head-and-neck-squamous-cell-carcinomas-derives-primarily-from-functionally-anergic-cd4-tils-in-the-presence-of-pd-l1-tams
#10
Austin K Mattox, Jina Lee, William H Westra, Robert H Pierce, Ronald Ghossein, William C Faquin, Thomas J Diefenbach, Luc G Morris, Derrick T Lin, Lori J Wirth, Armida Lefranc-Torres, Eiichi Ishida, Patrick D Chakravarty, Lauren Johnson, Yang C Zeng, Huabiao Chen, Mark C Poznansky, Neil M Iyengar, Sara I Pai
Oral tongue squamous cell carcinoma (OTSCC) is the most common oral cavity tumor. In this study, we examined the basis for the activity of programmed cell death protein (PD-1)-based immune checkpoint therapy that is being explored widely in head and neck cancers. Using multispectral imaging, we systematically investigated the OTSCC tumor microenvironment (TME) by evaluating the frequency of PD-1 expression in CD8+ , CD4+ , and FoxP3+ tumor-infiltrating lymphocytes (TIL). We also defined the cellular sources of PD-1 ligand (PD-L1) to evaluate the utility of PD-1:PD-L1 blocking antibody therapy in this patient population...
November 15, 2017: Cancer Research
https://www.readbyqxmd.com/read/28900524/distal-intersection-syndrome-progressing-to-extensor-pollicis-longus-tendon-rupture-a-case-report-with-sonographic-findings
#11
Ross Mattox, Patrick J Battaglia, Frank Scali, Kathy Ottolini, Norman W Kettner
The purpose of this case report is to describe the value of musculoskeletal ultrasound (US) in diagnosing both distal intersection syndrome (DIS) and rupture of the extensor pollicis longus (EPL) tendon in the same patient. A 38-year-old female presented for evaluation of a painful bump of unknown etiology on the dorsolateral aspect of her non-dominant wrist. US demonstrated tenosynovitis distal to Lister's tubercle of the EPL and extensor carpi radialis tendon sheaths, consistent with DIS. Immobilization therapy was employed, during which time the patient suffered rupture of the EPL tendon...
September 2017: Journal of Ultrasound
https://www.readbyqxmd.com/read/28825869/cancer-cachexia-cause-diagnosis-and-treatment
#12
Todd W Mattox
Patients with cancer frequently experience unintended weight loss due to gastrointestinal (GI) dysfunction caused by the malignancy or treatment of the malignancy. However, others may present with weight loss related to other symptoms not clearly associated with identifiable GI dysfunction such as anorexia and early satiety. Cancer cachexia (CC) is a multifactorial syndrome that is generally characterized by ongoing loss of skeletal muscle mass with or without fat loss, often accompanied by anorexia, weakness, and fatigue...
October 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28822212/comparison-of-start-and-salt-triage-methodologies-to-reference-standard-definitions-and-to-a-field-mass-casualty-simulation
#13
COMPARATIVE STUDY
Salvatore Silvestri, Adam Field, Neal Mangalat, Tory Weatherford, Christopher Hunter, Zoe McGowan, Zachary Stamile, Trevor Mattox, Tanner Barfield, Aarian Afshari, George Ralls, Linda Papa
OBJECTIVES: We compared Sort, Assess, Lifesaving Intervention, Treatment/Transport (SALT) and Simple Triage and Rapid Treatment (START) triage methodologies to a published reference standard, and evaluated the accuracy of the START method applied by emergency medical services (EMS) personnel in a field simulation. DESIGN: Simulated mass casualty incident (MCI). Paramedics trained in START triage assigned each victim to green (minimal), yellow (delayed), red (immediate), or black (dead) categories...
2017: American Journal of Disaster Medicine
https://www.readbyqxmd.com/read/28550191/the-level-of-deletion-17p-and-bi-allelic-inactivation-of-tp53-has-a-significant-impact-on-clinical-outcome-in-multiple-myeloma
#14
LETTER
Sharmilan Thanendrarajan, Erming Tian, Pingping Qu, Pankaj Mathur, Carolina Schinke, Frits van Rhee, Maurizio Zangari, Leo Rasche, Niels Weinhold, Daisy Alapat, William Bellamy, Cody Ashby, Sandra Mattox, Joshua Epstein, Shmuel Yaccoby, Bart Barlogie, Antje Hoering, Michael Bauer, Brian A Walker, Faith E Davies, Gareth J Morgan
No abstract text is available yet for this article.
September 2017: Haematologica
https://www.readbyqxmd.com/read/28515857/contrast-use-in-relation-to-the-arterial-access-site-for-percutaneous-coronary-intervention-a-comprehensive-meta-analysis-of-randomized-trials
#15
Rahman Shah, Anthony Mattox, M Rehan Khan, Chalak Berzingi, Abdul Rashid
AIM: To compare the amount of contrast used during percutaneous coronary intervention (PCI) via trans-radial access (TRA) vs trans-femoral access (TFA). METHODS: Scientific databases and websites were searched for:randomizedcontrolledtrials (RCTs). Data were extracted by two independent reviewers and was summarized as the weighted mean difference (WMD) of contrast used with a 95%CI using a random-effects model. RESULTS: The meta-analysis included 13 RCTs with a total of 3165 patients...
April 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/28489996/cancer-associated-mutations-in-endometriosis-without-cancer
#16
Michael S Anglesio, Nickolas Papadopoulos, Ayse Ayhan, Tayyebeh M Nazeran, Michaël Noë, Hugo M Horlings, Amy Lum, Siân Jones, Janine Senz, Tamer Seckin, Julie Ho, Ren-Chin Wu, Vivian Lac, Hiroshi Ogawa, Basile Tessier-Cloutier, Rami Alhassan, Amy Wang, Yuxuan Wang, Joshua D Cohen, Fontayne Wong, Adnan Hasanovic, Natasha Orr, Ming Zhang, Maria Popoli, Wyatt McMahon, Laura D Wood, Austin Mattox, Catherine Allaire, James Segars, Christina Williams, Cristian Tomasetti, Niki Boyd, Kenneth W Kinzler, C Blake Gilks, Luis Diaz, Tian-Li Wang, Bert Vogelstein, Paul J Yong, David G Huntsman, Ie-Ming Shih
BACKGROUND: Endometriosis, defined as the presence of ectopic endometrial stroma and epithelium, affects approximately 10% of reproductive-age women and can cause pelvic pain and infertility. Endometriotic lesions are considered to be benign inflammatory lesions but have cancerlike features such as local invasion and resistance to apoptosis. METHODS: We analyzed deeply infiltrating endometriotic lesions from 27 patients by means of exomewide sequencing (24 patients) or cancer-driver targeted sequencing (3 patients)...
May 11, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28416672/bisulfite-converted-duplexes-for-the-strand-specific-detection-and-quantification-of-rare-mutations
#17
Austin K Mattox, Yuxuan Wang, Simeon Springer, Joshua D Cohen, Srinivasan Yegnasubramanian, William G Nelson, Kenneth W Kinzler, Bert Vogelstein, Nickolas Papadopoulos
The identification of mutations that are present at low frequencies in clinical samples is an essential component of precision medicine. The development of molecular barcoding for next-generation sequencing has greatly enhanced the sensitivity of detecting such mutations by massively parallel sequencing. However, further improvements in specificity would be useful for a variety of applications. We herein describe a technology (BiSeqS) that can increase the specificity of sequencing by at least two orders of magnitude over and above that achieved with molecular barcoding and can be applied to any massively parallel sequencing instrument...
May 2, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28381624/eye-development-in-the-four-eyed-fish-anableps-anableps-cranial-and-retinal-adaptations-to-simultaneous-aerial-and-aquatic-vision
#18
Louise N Perez, Jamily Lorena, Carinne M Costa, Maysa S Araujo, Gabriela N Frota-Lima, Gabriel E Matos-Rodrigues, Rodrigo A P Martins, George M T Mattox, Patricia N Schneider
The unique eyes of the four-eyed fish Anableps anableps have long intrigued biologists. Key features associated with the bulging eye of Anableps include the expanded frontal bone and the duplicated pupils and cornea. Furthermore, the Anableps retina expresses different photoreceptor genes in dorsal and ventral regions, potentially associated with distinct aerial and aquatic stimuli. To gain insight into the developmental basis of the Anableps unique eye, we examined neurocranium and eye ontogeny, as well as photoreceptor gene expression during larval stages...
April 12, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28365664/complications-of-peripheral-venous-access-devices-prevention-detection-and-recovery-strategies
#19
COMPARATIVE STUDY
Elizabeth A Mattox
Most hospitalized patients have placement of a peripheral venous access device, either a short peripheral catheter or a peripherally inserted central catheter. Compared with central venous catheters that are not peripherally inserted, the other 2 types are generally perceived by health care providers as safer and less complicated to manage, and less emphasis is placed on the prevention and management of complications. Expertise of nurses in inserting, managing, and removing these devices may reduce the likelihood of complications, and increased recognition of complications associated with use of the devices is important to ensure continued improvements in the safety, quality, and efficiency of health care...
April 2017: Critical Care Nurse
https://www.readbyqxmd.com/read/28350269/review-of-a-single-surgeon-s-stapedotomy-cases-performed-with-a-nickel-titanium-prosthesis-over-a-14-year-period
#20
Natalie Justicz, Kaitlyn F Strickland, Kevin K Motamedi, Douglas E Mattox
CONCLUSION: Stapes surgery with a nickel titanium prosthesis is a safe and well-tolerated procedure that leads to a significant improvement in hearing outcomes. OBJECTIVE: To identify the efficacy and safety of stapedotomy procedures performed with a nickel titanium prosthesis for patients with otosclerosis. METHODS: A review of 431 unique stapedotomies performed over 14 years by a single surgeon at an academic tertiary care center yielded 312 cases with nickel titanium prosthesis that met inclusion criteria of otosclerosis diagnosis, initial surgery in operative ear, and presence of pre-operative and post-operative audiograms...
April 2017: Acta Oto-laryngologica
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