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Medical disorders in pregnancy

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https://www.readbyqxmd.com/read/29143329/matsubara-takahashi-cervix-holding-technique-for-massive-postpartum-hemorrhage-in-patients-with-placenta-previa-with-or-without-placenta-accreta-spectrum-disorders
#1
Hironori Takahashi, Akihide Ohkuchi, Rie Usui, Hirotada Suzuki, Yosuke Baba, Shigeki Matsubara
OBJECTIVE: To determine the efficacy and safety of the Matsubara-Takahashi cervix-holding technique (MT-holding) for achieving hemostasis for postpartum hemorrhage (PPH). METHODS: The present retrospective observational study included data from deliveries that occurred between January 1, 2004, and December 31, 2014, at the Department of Obstetrics and Gynecology, Jichi Medical University, Shimotsuke, Japan. Deliveries were included where patients experienced blood loss greater than 2500 mL and MT-holding was used...
November 16, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29137553/relationship-between-pregnancy-complications-and-psychiatric-disorders-a-population-based-study-with-a-matched-control-group
#2
Christina D Kang-Yi, Sara L Kornfield, C Neill Epperson, David S Mandell
OBJECTIVES: This study sought to identify whether pregnancy complications differ between women with and without a psychiatric disorder diagnosis prior to pregnancy. METHODS: Women who gave birth between 2007 and 2009 in Pennsylvania and were enrolled in Medicaid from one year prior to their pregnancy until their delivery were included (N=9,930); those with psychiatric disorders were compared with a matched control group (N=4,965 for each). Logistic regression analysis estimated the odds of having a pregnancy complication among those with a psychiatric diagnosis prior to pregnancy, adjusting for demographic characteristics and chronic general medical conditions...
November 15, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29127207/perinatal-outcomes-after-treatment-with-adhd-medication-during-pregnancy
#3
Ulrika Nörby, Birger Winbladh, Karin Källén
OBJECTIVES: To analyze perinatal outcomes after maternal use of attention-deficit/hyperactivity disorder (ADHD) medication during pregnancy. METHODS: The study included singletons born between 2006 and 2014 in Sweden. Data on prescription drug use, pregnancies, deliveries, and the newborn infants' health were obtained from the Swedish Medical Birth Register, the Prescribed Drug Register, and the Swedish Neonatal Quality Register. We compared infants exposed to ADHD medication during pregnancy with infants whose mothers never used these drugs and infants whose mothers used ADHD medication before or after pregnancy...
November 10, 2017: Pediatrics
https://www.readbyqxmd.com/read/29120249/alcohol-addiction-the-safety-of-available-approved-treatment-options
#4
Mariangela Antonelli, Anna Ferrulli, Luisa Sestito, Gabriele A Vassallo, Claudia Tarli, Carolina Mosoni, Maria M Rando, Antonio Mirijello, Antonio Gasbarrini, Giovanni Addolorato
Alcohol Use Disorder (AUD) is a leading cause of mortality and morbidity worldwide. At present disulfiram, naltrexone and acamprosate are approved for the treatment of AUD in U.S. and Europe. Nalmefene is approved in Europe and sodium oxybate is approved in Italy and Austria only. Baclofen received a "temporary recommendation for use" in France. Areas covered. The safety of the medications mentioned above on liver, digestive system, kidney function, nervous system, pregnancy and lactation and their possible side effects are described and discussed...
November 9, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/29117926/-maternal-deaths-due-to-hypertensive-disorders-results-from-the-french-confidential-enquiry-into-maternal-deaths-2010-2012
#5
M Dreyfus, P Weber, L Zieleskiewicz
Between 2010 and 2012, the rate of maternal death caused by hypertensive disorders (0,5/100,000 living birth) was reduced by 50% compared to the 2007-2009 period. Hypertensive disorders were responsible from 5% of maternal deaths and from 10% of direct maternal mortality. Eleven deaths happened during the postpartum period but 9 hypertensive complications began before delivery. Seventy percent of these deaths seem to be avoidable. The main causes of suboptimal management were: unappropriated or insufficient obstetrical and anesthetic treatments, undiagnosed HELLP syndrome and subcapsular liver hematoma, delayed treatment...
November 5, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29116416/postpartum-outcomes-of-a-pilot-prenatal-care-based-psychosocial-intervention-for-ptsd-during-pregnancy
#6
Linda Weinreb, Melodie Wenz-Gross, Carole Upshur
This study examines postpartum posttraumatic stress disorder (PTSD) symptoms and secondary outcomes including postpartum depression and birth outcomes for pregnant women who screened positive for PTSD and received a psychosocial education intervention compared to women with PTSD in the usual prenatal care setting. All women entering prenatal care at two federally qualified health centers were screened for symptoms of current PTSD; one site was selected randomly to have prenatal care advocates deliver eight Seeking Safety topics for women with clinical or subclinical PTSD...
November 7, 2017: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29113876/-indirect-causes-of-maternal-deaths-except-stroke-cardiovascular-diseases-and-infections-results-from-the-french-confidential-enquiry-into-maternal-deaths-2010-2012
#7
V Le Guern, M Rossignol, A Proust
Maternal deaths of indirect causes result of a preexisting disease or an affection appeared during the pregnancy without any relationship with obstetrical causes, but worsened by the physiological effects of pregnancy. Among the 23 deaths of indirect cause related to a preexisiting pathology, 22 (96 %) have been analyzed by the expert comity. A known or preexisting chronic disease was documented in 16 patients (sick-cell disorder, n=3, treated epilepsy, n=3, intracerebral carvenomas, n=1, multifocal glial tumor, n=1, breast cancer, n=1, systemic lupus, n=1, diabetes mellitus, n=3, antiphospholipid syndrome, n=1)...
November 4, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29112657/placental-complications-associated-with-psychostimulant-use-in-pregnancy
#8
Jacqueline M Cohen, Sonia Hernández-Díaz, Brian T Bateman, Yoonyoung Park, Rishi J Desai, Kathryn J Gray, Elisabetta Patorno, Helen Mogun, Krista F Huybrechts
OBJECTIVE: To evaluate whether psychostimulants used to treat attention-deficit/hyperactivity disorder (ADHD) are associated with risk of adverse placental-associated pregnancy outcomes including preeclampsia, placental abruption, growth restriction, and preterm birth. METHODS: We designed a population-based cohort study in which we examined a cohort of pregnant women and their liveborn neonates enrolled in Medicaid from 2000 to 2010. Women who received amphetamine-dextroamphetamine or methylphenidate monotherapy in the first half of pregnancy were compared with unexposed women...
November 3, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29104681/association-between-beta-sympathomimetic-tocolysis-and-risk-of-autistic-spectrum-disorders-behavioural-and-developmental-outcome-in-toddlers
#9
Mengühan Araz Altay, Işık Görker, Rakhshanda Aslanova, Leyla Bozatlı, Nesrin Turan, Petek Balkanlı Kaplan
AIM: To investigate whether maternal intravenous beta-mimetic tocolytic therapy increases the risk of autistic spectrum disorders (ASD) and poorer behavioural and developmental outcomes. METHOD: Our study is a prospective case-control study among 90 children between 1.5 and three years old. Cases (n = 46) were toddlers with betamimetic tocolytic exposure; control group toddlers (n = 44) were tocolytic untreated. Treated and untreated groups were also divided into subgroups: term and preterm delivered...
October 15, 2017: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29099558/antidepressant-exposure-during-pregnancy-and-risk-of-autism-in-the-offspring-2-do-the-new-studies-add-anything-new
#10
Chittaranjan Andrade
BACKGROUND: During the past year, at least 5 new studies, all observational in design, examined the risk of autism spectrum disorder (ASD) in children exposed to antidepressant medication in utero. These studies had not found inclusion in the many systematic reviews and meta-analyses that had also been published in the past year. METHODS: Noteworthy methods and findings of the new studies are summarized. One of these studies is examined in detail to help the reader understand methodological and conceptual issues that are critical in the field...
September 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29097857/like-the-eye-of-the-tiger-inpatient-psychiatric-facility-exclusionary-criteria-and-its-knockout-of-the-emergency-psychiatric-patient
#11
Veronica Tucci, John Liu, Anu Matorin, Asim Shah, Nidal Moukaddam
Context: Over 6% of all emergency department (ED) visits in the United States involve primary mental health or behavioral issues. The patients are stabilized in the ED but frequently require admission to an inpatient psychiatric unit or institution for longer term treatment and management. To facilitate this process, an emergency physician (EP) must first "medically clear" the patient as stable for transfer. At present, there is no interdisciplinary consensus regarding the necessary elements of the medical clearance or stability assessment process...
October 2017: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29093561/hypertensive-disorders-of-pregnancy-a-strong-risk-factor-for-subsequent-hypertension-5-years-after-delivery
#12
Asako Mito, Naoko Arata, Dongmei Qiu, Naoko Sakamoto, Atsuko Murashima, Atsuhiro Ichihara, Ryu Matsuoka, Akihiko Sekizawa, Yukihiro Ohya, Michihiro Kitagawa
Hypertensive disorders of pregnancy are known to be a risk factor for future cardiovascular diseases. In contrast, there is a paucity of data on the not so distant future prognosis of hypertensive disorders of pregnancy. In the present study, we evaluated the incidence of the diseases causing cardiovascular problems (hypertension, diabetes mellitus, dyslipidemia and metabolic syndrome) 5 years after delivery in Japanese women with hypertensive disorders of pregnancy. We performed a double-cohort study and compared medical conditions between women with and without a history of hypertensive disorders of pregnancy...
November 2, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29093070/high-risk-of-postpartum-relapses-in-neuromyelitis-optica-spectrum-disorder
#13
Eric C Klawiter, Riley Bove, Liene Elsone, Enrique Alvarez, Nadja Borisow, Melissa Cortez, Farrah Mateen, Maureen A Mealy, Jaime Sorum, Kerry Mutch, Sean M Tobyne, Klemens Ruprecht, Guy Buckle, Michael Levy, Dean Wingerchuk, Friedemann Paul, Anne H Cross, Anu Jacobs, Tanuja Chitnis, Brian Weinshenker
OBJECTIVE: To study the effect of pregnancy on the frequency of neuromyelitis optica spectrum disorder (NMOSD) relapse and evaluate rates of pregnancy-related complications in an international multicenter setting. METHODS: We administered a standardized survey to 217 women with NMOSD from 7 medical centers and reviewed their medical records. We compared the annualized relapse rate (ARR) during a baseline period 2 years prior to a participant's first pregnancy to that during pregnancy and to the 9 months postpartum...
November 1, 2017: Neurology
https://www.readbyqxmd.com/read/29091821/are-gastrointestinal-and-sleep-problems-associated-with-behavioral-symptoms-of-autism-spectrum-disorder
#14
Xiao-Lei Yang, Shuang Liang, Ming-Yang Zou, Cai-Hong Sun, Pan-Pan Han, Xi-Tao Jiang, Wei Xia, Li-Jie Wu
Many children with autism spectrum disorder (ASD) suffer from concurrent medical symptoms, including gastrointestinal (GI) and sleeping problems. However, there is limited information on the correlation between co-morbidities and autistic behavioral symptoms. In this study, we estimated the prevalence of GI and sleep problems in Chinese ASD children, examined the impacts of GI and sleep problems on autistic behavioral symptoms, and investigated the factors associated with GI and sleep problems. The survey included 169 ASD and 172 healthy children...
October 24, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29091783/neurodevelopmental-outcome-in-prenatally-diagnosed-isolated-agenesis-of-the-corpus-callosum
#15
Lise Folliot-Le Doussal, Alexandra Chadie, Marie Brasseur-Daudruy, Eric Verspyck, Pascale Saugier-Veber, Stéphane Marret
Neurodevelopmental outcome in children with agenesis of the corpus callosum (ACC) is correlated with the presence or absence of associated brain abnormalities. Indeed, neurodevelopmental outcome shows severe disabilities when the ACC is not isolated whereas in isolated forms, the neurologic development is mainly normal. Contrary to data in several published studies, the prognosis remains uncertain even in isolated forms, which may lead in France to medical termination of pregnancy. OBJECTIVE: To evaluate long-term neurodevelopmental outcome in children with prenatally diagnosed isolated ACC...
October 29, 2017: Early Human Development
https://www.readbyqxmd.com/read/29083536/bipolar-disorder-in-pregnancy-a-review-of-pregnancy-outcomes
#16
REVIEW
Debra A Scrandis
INTRODUCTION: Women with bipolar disorder may benefit from continuation of their medications during pregnancy, but there may be risks to the fetus associated with some of these medications. This article examines the evidence relating to the effect of bipolar disorder and pharmacologic treatments for bipolar disorder on pregnancy outcomes. METHODS: MEDLINE, CINAHL, ProQuest Dissertation & Theses, and the Cochrane Database of Systematic Reviews were searched for English-language studies published between 2000 and 2017, excluding case reports and integrative reviews...
October 30, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29083111/risk-factors-associated-with-hypertensive-disorders-of-pregnancy-within-an-urban-indigenous-population-in-south-western-sydney
#17
Al Daly, N Sriram, C Woodall, K Selvakumar, K Briggs, P Garg, L Russell, M Yu, K Beetson, A Hennessy, Tharawal Ams
BACKGROUND: The prevalence of hypertensive disorders of pregnancy (HDP) in Australia's urban Indigenous women is unknown. AIM: To explore the risk factors associated with HDP for a cohort of urban Indigenous women in South-Western Sydney, Australia METHODS AND MATERIALS: This study was conducted in partnership with the Tharawal Aboriginal Medical Service (TAMS). Women (18-45 years) were recruited at the clinic and community events. The quantitative questionnaire included obstetric history, personal and family history of hypertension...
October 30, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/29077514/obesity-in-women-insights-for-the-clinician
#18
Zujaja Tauqeer, Gricelda Gomez, Fatima Cody Stanford
As a leading cause of morbidity and mortality in the United States and worldwide, obesity is a disease that is frequently encountered in clinical practice today and requires a range of medical interventions. While obesity affects both men and women across all ages, multiple issues are particularly germane to women's health, particularly as obesity is more prevalent among women than men in the United States and obesity among women of reproductive health relates to the growing issue of childhood obesity. Discussed herein are the epidemiology and pathophysiology of obesity along with the impact of perinatal obesity on fetal programming...
October 27, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29073311/expanding-treatment-opportunities-for-hospitalized-patients-with-opioid-use-disorders
#19
Daniel Winetsky, Robert M Weinrieb, Jeanmarie Perrone
The prevalence of opioid use disorders (OUDs) is rising across the United States. Patients with OUDs are often hospitalized for medical conditions other than addiction, such as infection, injury, or pregnancy. These hospital admissions provide an opportunity for healthcare providers to initiate opioid agonist therapy with methadone or buprenorphine. Randomized trials have demonstrated the superior effectiveness of this treatment strategy, but its adoption by hospital providers has been slow. A number of barriers have impeded its implementation, including misperceptions about the regulation of opioid prescribing, limited resources for the transition to community- based treatment, and a lack of familiarity among clinicians about the appropriate initiation and dose adjustment of these opioid agonists for maintenance therapy...
October 18, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29069503/metabolomics-as-a-tool-to-identify-biomarkers-to-predict-and-improve-outcomes-in-reproductive-medicine-a-systematic-review
#20
Timothy Bracewell-Milnes, Srdjan Saso, Hossam Abdalla, Dimitrios Nikolau, Julian Norman-Taylor, Mark Johnson, Elaine Holmes, Meen-Yau Thum
BACKGROUND: Infertility is a complex disorder with significant medical, psychological and financial consequences for patients. With live-birth rates per cycle below 30% and a drive from the Human Fertilisation and Embryology Authority (HFEA) to encourage single embryo transfer, there is significant research in different areas aiming to improve success rates of fertility treatments. One such area is investigating the causes of infertility at a molecular level, and metabolomics techniques provide a platform for studying relevant biofluids in the reproductive tract...
November 1, 2017: Human Reproduction Update
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