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https://www.readbyqxmd.com/read/29144106/cognitive-reserve-as-a-variable-impacting-the-effectiveness-of-rehabilitation-on-balance-in-parkinson-s-disease
#1
Giulia Piccinini, Isabella Imbimbo, Diego Ricciardi, Daniele Coraci, Claudia Santilli, Maria R Lo Monaco, Claudia Loreti, Maria C Vulpiani, Maria C Silveri, Luca Padua
BACKGROUND: Cognitive reserve (CR) can be considered an active expression of brain resilience in response to damage. Several studies have shown the influence of CR on cognitive impairment and its relationship with cognitive function in Parkinson's disease (PD). AIM: To show if CR influences the effectiveness of balance rehabilitation in PD patients who performed a conventional rehabilitative treatment. DESIGN: Observational longitudinal study...
November 16, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29119036/technology-assisted-rehabilitation-of-writing-skills-in-parkinson-s-disease-visual-cueing-versus-intelligent-feedback
#2
Evelien Nackaerts, Alice Nieuwboer, Elisabetta Farella
Recent research showed that visual cueing can have both beneficial and detrimental effects on handwriting of patients with Parkinson's disease (PD) and healthy controls depending on the circumstances. Hence, using other sensory modalities to deliver cueing or feedback may be a valuable alternative. Therefore, the current study compared the effects of short-term training with either continuous visual cues or intermittent intelligent verbal feedback. Ten PD patients and nine healthy controls were randomly assigned to one of these training modes...
2017: Parkinson's Disease
https://www.readbyqxmd.com/read/29113472/cell-therapy-for-parkinson-s-disease
#3
Takao Yasuhara, Masahiro Kameda, Tatsuya Sasaki, Naoki Tajiri, Isao Date
Cell therapy for Parkinson's disease (PD) began in 1979 with the transplantation of fetal rat dopamine-containing neurons that improved motor abnormalities in the PD rat model with good survival of grafts and axonal outgrowth. Thirty years have passed since the 2 clinical trials using cell transplantation for PD patients were first reported. Recently, cell therapy is expected to develop as a realistic treatment option for PD patients owing to the advancement of biotechnology represented by pluripotent stem cells...
September 2017: Cell Transplantation
https://www.readbyqxmd.com/read/29102438/prediction-of-falls-in-subjects-suffering-from-parkinson-s-disease-multiple-sclerosis-and-stroke
#4
Ettore Beghi, Elisa Gervasoni, Elisabetta Pupillo, Elisa Bianchi, Angelo Montesano, Irene Aprile, Michela Agostini, Marco Rovaris, Davide Cattaneo
OBJECTIVE: To compare the risk of falls and fall predictors in patients with Parkinson's disease (PD), multiple sclerosis (MS) and stroke using the same study design. DESIGN: Multicenter prospective cohort study. SETTING: Three [masked] institutions for physical therapy and rehabilitation. PARTICIPANTS: Patients with PD, MS and stroke seen for rehabilitation. MAIN OUTCOME MEASURES: Functional scales were applied to investigate balance, disability, daily performance, self-confidence with balance, and social integration...
November 1, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29090092/current-understanding-of-the-molecular-mechanisms-in-parkinson-s-disease-targets-for-potential-treatments
#5
REVIEW
Panchanan Maiti, Jayeeta Manna, Gary L Dunbar
Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars compacta and subsequent reduction of dopamine levels in striatum are associated with motor deficits that characterize Parkinson's disease (PD). In addition, half of the PD patients also exhibit frontostriatal-mediated executive dysfunction, including deficits in attention, short-term working memory, speed of mental processing, and impulsivity. The most commonly used treatments for PD are only partially or transiently effective and are available or applicable to a minority of patients...
2017: Translational Neurodegeneration
https://www.readbyqxmd.com/read/29072042/active-exergames-to-improve-cognitive-functioning-in-neurological-disabilities-a-systematic-review-and-meta-analysis
#6
Gioia Mura, Mauro G Carta, Federica Sancassiani, Sergio Machado, Luca Prosperini
INTRODUCTION: Exergames represent a way to perform physical activity through active video games, serving as potentially useful tool in the field of neurorehabilitation. However, little is known regarding the possible role of exergames in improving cognitive functions in persons suffering from neurological disabilities. EVIDENCE ACQUISITION: A search for relevant articles was carried out on PubMed/Medline, Scopus, PEDro, and Google Scholar. Only randomized controlled studies and non-randomized but controlled studies were retained...
October 25, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29064806/-gait-disturbances-and-falls-in-various-types-of-dementias
#7
Katarzyna Knast, Agnieszka Gorzkowska, Izabela Bieniek, Monika Rudzińska-Bar
Dementia is a group of symptoms of damage of higher cortical functions. The causes of dementia include brain diseases, most often chronic and progressive, leading to cognitive impairment typical of these disorders. Apart from progressive cognitive deficits, dementias may coexist with mental disorders, sleep disorders, epileptic seizures, parkinsonism and other motor disorders. Motor disorders, including gait disturbances and falls, represent a serious challenge to the health of older adults and contribute to loss of mobility and independence...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29060886/a-wearable-ultrasonic-sensor-network-for-analysis-of-bilateral-gait-symmetry
#8
Karalikkadan Ashhar, Cheong Boon Soh, Keng He Kong
Analysis of bilateral gait symmetry and coordination is important in rehabilitation after lower-extremity trauma, prosthesis and neurovascular diseases. Moreover, it can act as a precursor of freezing of gait in Parkinson's disease. Current methods for gait symmetry analysis include Opto-electronic systems using multiple high-speed cameras, instrumented platforms etc. which are complex and costly. We propose a low-cost, wearable ultrasonic sensor network using readily available components, which is easy to use, portable and does not require complex calibration procedures...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060754/touch-free-reaching-task-for-parkinson-s-disease-patients-a-motion-sensing-approach
#9
Yousef Salimpour, Jui-Hong Chien, Chang-Chia Liu, Sangwon Lee, Sergio Guadix, Kelly A Mills, William S Anderson
The use of motion tracking devices in healthcare is under investigation. Although many motion tracking applications have been proposed to monitor the progress of rehabilitation, using such technology to quantify the progression or improvement of therapies for movement disorders is still scarce. In this study, we introduce a touch-free reaching task which uses a motion sensing device. Our motion tracking system combines a motion tracking device and visual feedback to implement a movement task for the evaluation of the state of motor functions impairment symptoms in Parkinson's disease and other movement disorders...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29060542/posturography-stability-score-generation-for-stroke-patient-using-kinect-fuzzy-based-approach
#10
Oishee Mazumder, Kingshuk Chakravarty, Debatri Chatterjee, Aniruddha Sinha, Abhijit Das
Aim of this paper is to formulate a posturography stability score for stroke patients using fuzzy logic. Postural instability is one of the prominent symptoms of stroke, dementia, parkinsons disease, myopathy, etc. and is the major precursor of fall. Conventional scoring techniques used to assess postural stability require manual intervention and are dependent on live interaction with physiotherapist. We propose a novel scoring technique to calculate static stability of a person using posturography features acquired by Kinect sensor, which do not require any manual intervention or expert guidance, is cost effective and hence are ideal for tele rehabilitation purpose...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29053448/the-effects-of-coding-schemes-on-vibrotactile-biofeedback-for-dynamic-balance-training-in-parkinson-s-disease-and-healthy-elderly-individuals
#11
Beom-Chan Lee, Alberto Fung, Timothy A Thrasher
A coding scheme for earlier versions of vibrotactile biofeedback systems for balance-related applications was primarily binary in nature, either off or on at a given threshold (range of postural tilt), making it unable to convey information about error magnitude. The purpose of this study was to explore the effects of two coding schemes (binary vs. continuous) for vibrotactile biofeedback during dynamic weight-shifting exercises that are common physical therapists' recommended balance exercises used in clinical settings...
October 16, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/29032012/continuous-subcutaneous-apomorphine-infusion-in-parkinson-s-disease-patients-with-cognitive-dysfunction-a-retrospective-long-term-follow-up-study
#12
Robbert W K Borgemeester, Teus van Laar
INTRODUCTION: Continuous apomorphine infusion (CAI) is an advanced therapy in fluctuating Parkinson's disease (PD). The use of CAI is controversial in PD patients with cognitive dysfunction including visual hallucinations (VHs), and orthostatic hypotension (OH). This study was set-up to analyze the effectiveness and safety of CAI in elderly PD patients with cognitive dysfunction. METHODS: This new-user cohort study identified fluctuating PD patients who started CAI treatment at the rehabilitation unit of Parkinson Expertise Center (RU-PEC) Groningen, from November 2004 until 2016...
September 29, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29031913/chronic-pain-and-pain-processing-in-parkinson-s-disease
#13
REVIEW
Pierre J Blanchet, Christine Brefel-Courbon
Pain is experienced by the vast majority of patients living with Parkinson's disease. It is most often of nociceptive origin, but may also be ascribed to neuropathic (radicular or central) or miscellaneous sources. The recently validated King's Parkinson's Disease Pain Scale is based on 7 domains including musculoskeletal pain, chronic body pain (central or visceral), fluctuation-related pain, nocturnal pain, oro-facial pain, pain with discolouration/oedema/swelling, and radicular pain. The basal ganglia integrate incoming nociceptive information and contribute to coordinated motor responses in pain avoidance and nocifensive behaviors...
October 12, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28967438/identification-of-specific-gait-patterns-in-patients-with-cerebellar-ataxia-spastic-paraplegia-and-parkinson-s-disease-a-non-hierarchical-cluster-analysis
#14
Mariano Serrao, Giorgia Chini, Matteo Bergantino, Diego Sarnari, Carlo Casali, Carmela Conte, Alberto Ranavolo, Christian Marcotulli, Martina Rinaldi, Gianluca Coppola, Fabiano Bini, Francesco Pierelli, Franco Marinozzi
Patients with degenerative neurological diseases such as cerebellar ataxia, spastic paraplegia, and Parkinson's disease often display progressive gait function decline that inexorably impacts their autonomy and quality of life. Therefore, considering the related social and economic costs, one of the most important areas of intervention in neurorehabilitation should be the treatment of gait abnormalities. This study aims to determine whether an entire dataset of gait parameters recorded in patients with degenerative neurological diseases can be clustered into homogeneous groups distinct from each other and from healthy subjects...
September 26, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28961738/cognitive-rehabilitation-in-parkinson-s-disease-is-it-feasible
#15
Roberta Biundo, Luca Weis, Eleonora Fiorenzato, Angelo Antonini
Parkinson's disease (PD) is a common neurodegenerative disorder, characterized by motor and non-motor symptoms. Dementia is one of the most relevant non-motor symptoms considering its functional affect on PD patients' activities of daily living and family members' wellbeing. Cognitive abnormalities in PD are heterogeneous and reliable biomarkers to detect patients at risk for dementia early on remain to be identified. Pharmacological treatments specifically for PD dementia and mild cognitive impairment are lacking, and alternative approaches have recently been implemented, including cognitive rehabilitation...
November 1, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28940855/long-term-effects-of-cognitive-rehabilitation-on-brain-functional-outcome-and-cognition-in-parkinson-s-disease
#16
María Díez-Cirarda, Natalia Ojeda, Javier Peña, Alberto Cabrera-Zubizarreta, Olaia Lucas-Jiménez, Juan Carlos Gómez-Esteban, Maria Ángeles Gómez-Beldarrain, Naroa Ibarretxe-Bilbao
BACKGROUND: Cognitive rehabilitation has demonstrated efficacy in producing short-term cognitive and brain changes in Parkinson's disease (PD) patients. To date, no study has assessed the long-term effects of cognitive rehabilitation using neuroimaging techniques in PD. The aim was to assess the longitudinal effects of a 3-month cognitive rehabilitation program evaluating the cognitive, behavioural and neuroimaging changes after 18 months. METHODS: Fifteen PD patients underwent a cognitive, behavioural and neuroimaging assessment at pre-treatment (T0 ), post-treatment (T1 ) and after 18-months (T2 )...
September 23, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28890381/the-link-between-parkinson-s-disease-and-rapid-eye-movement-sleep-behavior-disorder-with-dream-enactment-possible-implications-for-early-rehabilitation
#17
Brian P Johnson, Kelly P Westlake
The purpose of this paper is twofold. First, to inform readers of the link between the loss of motor inhibition during rapid eye movement (REM) sleep dreaming, diagnosed as REM sleep behavior disorder (RBD), and the future onset of neurodegenerative disorders, such as Parkinson's Disease and dementia with lewy bodies. It has been reported that motor disinhibition during rapid eye movement sleep often precedes onset of these disorders by years or even decades. Second, to consider that identification of RBD and the early involvement of rehabilitation and/or development of home exercise plans may aid in prolonging and even increasing function, independence, and quality of life should such neurodegenerative disorders develop later in life...
September 7, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28890341/cueing-for-people-with-parkinson-s-disease-with-freezing-of-gait-a-narrative-review-of-the-state-of-the-art-and-novel-perspectives
#18
REVIEW
Pieter Ginis, Evelien Nackaerts, Alice Nieuwboer, Elke Heremans
Freezing, which manifests during gait and other movements, is an incapacitating motor symptom experienced by many patients with Parkinson's disease (PD). In rehabilitation, auditory and visual cueing methods are commonly applied to evoke a more goal-directed type of motor control and, as such, reduce freezing severity in patients with PD. In this narrative review, we summarize the current evidence regarding the effects of external cueing in patients with PD with freezing of gait (FOG) and provide suggestions on how to further improve cueing effectiveness with emerging technological developments...
September 7, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28858808/using-inertial-sensors-to-automatically-detect-and-segment-activities-of-daily-living-in-people-with-parkinson-s-disease
#19
Hung Nguyen, Karina Lebel, Sarah Bogard, Etienne Goubault, Patrick Boissy, Qpn Clinicians, Christian Duval
Wearable sensors such as Inertial Measuring Units (IMUs) have been widely used to measure the quantity of physical activities during daily living in healthy and people with movement disorders through activity classification. These sensors have the potential to provide valuable information to evaluate the quality of the movement during activities of daily living (ADL) such as walking, sitting down and standing up, which could help clinicians to monitor rehabilitation and pharmaceutical interventions. However, high accuracy in the detection and segmentation of these activities is necessary for proper evaluation of the quality of the performance within a given segment...
August 25, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28851443/the-pd-comm-trial-a-protocol-for-the-process-evaluation-of-a-randomised-trial-assessing-the-effectiveness-of-two-types-of-slt-for-people-with-parkinson-s-disease
#20
Patricia Masterson-Algar, Christopher R Burton, Marian C Brady, Avril Nicoll, Carl E Clarke, Caroline Rick, Max Hughes, Pui Au, Christina H Smith, Catherine M Sackley
BACKGROUND: The PD COMM trial is a phase III multi-centre randomised controlled trial whose aim is to evaluate the effectiveness and cost-effectiveness of two approaches to speech and language therapy (SLT) compared with no SLT intervention (control) for people with Parkinson's disease who have self-reported or carer-reported problems with their speech or voice. Our protocol describes the process evaluation embedded within the outcome evaluation whose aim is to evaluate what happened at the time of the PD COMM intervention implementation and to provide findings that will assist in the interpretation of the PD COMM trial results...
August 29, 2017: Trials
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