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https://www.readbyqxmd.com/read/28637142/feasibility-of-a-cognitive-strategy-training-intervention-for-people-with-parkinson-s-disease
#1
Erin R Foster, Daniel Spence, Joan Toglia
PURPOSE: To investigate the feasibility of a novel client-centered cognitive strategy training intervention for people with Parkinson's disease (PD). MATERIALS AND METHODS: This was a case series of seven people with PD without dementia but with subjective cognitive decline. The intervention involved ≥5 treatment sessions at the participant's home. Participant acceptance and engagement were assessed by the Credibility/Expectancy Questionnaire (CEQ), Client Satisfaction Questionnaire (CSQ), enjoyment and effort ratings, and homework completion...
February 23, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28629269/aquatic-obstacle-training-improves-freezing-of-gait-in-parkinson-s-disease-patients-a-randomized-controlled-trial
#2
Zhizhong Zhu, Miaomiao Yin, Liling Cui, Ying Zhang, Weijia Hou, Yaqing Li, Hua Zhao
OBJECTIVE: Our aim was to evaluate the effect of aquatic obstacle training on balance parameters in comparison with a traditional aquatic therapy in patients with Parkinson's disease. DESIGN: A randomized single-blind controlled trial. SETTING: Outpatients in the rehabilitation department. SUBJECTS: A total of 46 patients with Parkinson's disease in Hoehn-Yahr stage 2-3. INTERVENTIONS: Participants were randomly assigned to (1) aquatic therapy or (2) obstacle aquatic therapy...
June 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28626755/can-rehabilitation-influence-the-efficiency-of-control-signals-in-complex-motion-strategies
#3
Joanna Cholewa, Jaroslaw Cholewa, Agnieszka Gorzkowska, Andrzej Malecki, Arkadiusz Stanula
The factor determining quality of life in Parkinson's disease (PD) is the worsening of a patient's walking ability. The use of external stimuli can improve gait when performing complex motor patterns. The aim of this study was to evaluate the effect of rehabilitation on the effectiveness of control signals in people with PD. The study was performed on 42 people with idiopathic PD in the third stage of disease. The control group consisted of 19 patients who did not participate in rehabilitation activities. The experimental group was systematically participating in rehabilitation activities twice a week (60 minutes) for 9 months...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28615996/international-society-of-sports-nutrition-position-stand-safety-and-efficacy-of-creatine-supplementation-in-exercise-sport-and-medicine
#4
REVIEW
Richard B Kreider, Douglas S Kalman, Jose Antonio, Tim N Ziegenfuss, Robert Wildman, Rick Collins, Darren G Candow, Susan M Kleiner, Anthony L Almada, Hector L Lopez
Creatine is one of the most popular nutritional ergogenic aids for athletes. Studies have consistently shown that creatine supplementation increases intramuscular creatine concentrations which may help explain the observed improvements in high intensity exercise performance leading to greater training adaptations. In addition to athletic and exercise improvement, research has shown that creatine supplementation may enhance post-exercise recovery, injury prevention, thermoregulation, rehabilitation, and concussion and/or spinal cord neuroprotection...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28606769/computer-assisted-cognitive-rehabilitation-on-freezing-of-gait-in-parkinson-s-disease-a-pilot-study
#5
Valeria Dibilio, Alessandra Nicoletti, Giovanni Mostile, Giacomo Portaro, Antonina Luca, Francesco Patti, Mario Zappia
BACKGROUND: In Parkinson's Disease (PD), effects of a cognitive training have been systematically evaluated only for cognitive and behavioral outcome measures, with mild to moderate effects. Despite the demonstrated interplay between cognition and gait, no studies have investigated the effect of cognitive rehabilitation protocols on gait in PD. METHODS: Patients affected by PD with freezing of gait were treated twice a week for six weeks with one hour sessions of computer-assisted training of attention ability and information processing tasks...
June 9, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28597694/everyday-functioning-of-people-with-parkinson-s-disease-and-impairments-in-executive-function-a-qualitative-investigation
#6
Aleksandra Kudlicka, John V Hindle, Laura E Spencer, Linda Clare
PURPOSE: Executive function is the key area of cognitive impairment in Parkinson's disease. This study investigated how cognitive difficulties impact on everyday life of people with Parkinson's disease and their carers, and whether they explicitly mention executive-type difficulties. METHODS: Semistructured interviews with 11 people with Parkinson's disease and six carers were analyzed thematically. People with Parkinson's disease performed within the normal range on cognitive screening tests, but all had abnormal scores on tests of executive function...
June 9, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28582720/a-little-trouble-getting-started-initial-slowness-in-parkinson-s-disease-step-negotiation
#7
Amanda E Stone, Jared W Skinner, Hyo Keun Lee, Chris J Hass
Bradykinesia is a prominent problem for persons with Parkinson's disease (PD) and has been studied extensively with upper extremity tasks; however there is a lack of research examining bradykinesia in targeted lower extremity tasks related to mobility. Navigating steps and curbs are challenging tasks for older adults and neurologically impaired and thus utilizing these behaviors provides ecological validity to the study of bradykinesia. Herein we assess differences in step negotiation performance between individuals with PD and aged matched older adults...
May 31, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28579506/does-perturbation-training-prevent-falls-after-discharge-from-stroke-rehabilitation-a-prospective-cohort-study-with-historical-control
#8
Avril Mansfield, Alison Schinkel-Ivy, Cynthia J Danells, Anthony Aqui, Raabeae Aryan, Louis Biasin, Vincent G DePaul, Elizabeth L Inness
BACKGROUND: Individuals with stroke fall frequently, and no exercise intervention has been shown to prevent falls post stroke. Perturbation-based balance training (PBT), which involves practicing reactions to instability, shows promise for preventing falls in older adults and individuals with Parkinson's disease. This study aimed to determine if PBT during inpatient stroke rehabilitation can prevent falls after discharge into the community. METHODS: Individuals with subacute stroke completed PBT as part of routine inpatient rehabilitation (n = 31)...
June 1, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28573883/longitudinal-falls-data-in-parkinson-s-disease-feasibility-of-fall-diaries-and-effect-of-attrition
#9
Heather Hunter, Lynn Rochester, Rosie Morris, Sue Lord
BACKGROUND: Identifying causes of falls for people with Parkinson's disease has met with limited success. Prospective falls measurement using the "gold standard" approach is challenging. This paper examines the process and outcomes associated with longitudinal falls reporting in this population. METHODS: Participants were recruited from ICICLE-GAIT (a collaborative study with ICICLE-PD; an incident cohort study). Monthly falls diaries were examined over 48 months for accuracy of data and rate of attrition...
June 2, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28564666/a-comprehensive-approach-to-deep-brain-stimulation-for-movement-disorders
#10
Umer Akbar, Wael F Asaad
Deep brain stimulation (DBS) is a well-established form of neuromodulation, used primarily for movement disorders such as Parkinson's disease (PD) and Essential Tremor (ET). The selection of patients who will benefit most from DBS depends on a team of clinicians from various disciplines, including neurology, neurosurgery, psychiatry, neuropsychology and rehabilitation specialists. The actual surgical procedure can take many forms. We apply a combination of multidisciplinary, team-based evaluations and intra-operative neurophysiology, test stimulation and imaging to optimize DBS therapy for individual patients...
June 1, 2017: Rhode Island Medical Journal
https://www.readbyqxmd.com/read/28552234/rehabilitation-training-in-neural-restitution
#11
Susanne Clinch, Monica Busse, Mate D Döbrössy, Stephen B Dunnett
Over the last decade, neural transplantation has emerged as one of the more promising, albeit highly experimental, potential therapeutics in neurodegenerative disease. Preclinical studies in rat lesion models of Huntington's disease (HD) and Parkinson's disease (PD) have shown that transplanted precursor neuronal tissue from a fetus into the lesioned striatum can survive, integrate, and reconnect circuitry. Importantly, specific training on behavioral tasks that target striatal function is required to encourage functional integration of the graft to the host tissue...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/28552230/strategies-for-bringing-stem-cell-derived-dopamine-neurons-to-the-clinic-the-kyoto-trial
#12
Jun Takahashi
Concerted efforts are realizing cell-based therapy for Parkinson's disease (PD). In this chapter, I describe efforts at the Center for iPS Cell Research and Application (CiRA), Kyoto University. These efforts use induced pluripotent stem cells (iPSCs) as donor cells. The iPSCs were established as human leukocyte antigen homozygous at CiRA and are intended for allogeneic transplantation. Our manufacturing protocol includes a feeder-free cell culture with laminin fragment LM511-E8 and the sorting of CORIN(+) cells...
2017: Progress in Brain Research
https://www.readbyqxmd.com/read/28527231/nordic-walking-improves-trunk-stability-and%C3%A2-gait-spatial-temporal-characteristics-in%C3%A2-people-with-parkinson-disease
#13
Marie-Anne Gougeon, Lei Zhou, Julie Nantel
BACKGROUND: This study aimed to assess the effect of walking with Nordic walking (NW) poles on postural stability and gait spatial-temporal characteristics in individuals with PD and to determine the cognitive load associated operating the poles. METHODS: Twelve individuals with PD (age: 61.6±11.7) were asked to perform four 90 s walking trials; with/without poles and with/without verbal fluency task (category fluency) after a 6-week independent NW training. We assessed gait spatial-temporal characteristics, and trunk postural stability using the APDM accelerometry system...
May 13, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28511125/the-many-facets-of-motor-learning-and-their-relevance-for-parkinson-s-disease
#14
REVIEW
Lucio Marinelli, Angelo Quartarone, Mark Hallett, Giuseppe Frazzitta, Maria Felice Ghilardi
The final goal of motor learning, a complex process that includes both implicit and explicit (or declarative) components, is the optimization and automatization of motor skills. Motor learning involves different neural networks and neurotransmitters systems depending on the type of task and on the stage of learning. After the first phase of acquisition, a motor skill goes through consolidation (i.e., becoming resistant to interference) and retention, processes in which sleep and long-term potentiation seem to play important roles...
July 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28505999/efficacy-of-a-combined-therapeutic-approach-in-the-management-of-pisa-syndrome
#15
Siria Di Martino, Elisa Unti, Caterina Tramonti, Sonia Mazzucchi, Ubaldo Bonuccelli, Bruno Rossi, Roberto Ceravolo, Carmelo Chisari
BACKGROUND: Pisa syndrome (PS) represents an important source of disability in Parkinson's disease (PD). Currently no consensus has been reached on its definition or diagnostic criteria, and therapeutic approaches are unspecific and often futile. Recently the role of abdominal muscles, and in particular of the external oblique (EO), in the pathogenesis of PS was hypothesized. OBJECTIVES: To evaluate the role of EO and propose a combined therapeutic approach in the management of PS...
May 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28486826/a-study-investigating-the-experience-of-working-for-people-with-parkinson-s-and-the-factors-that-influence-workplace-success
#16
Rebecca L Mullin, K Ray Chaudhuri, Thomasin C Andrews, Anne Martin, Stella Gay, Claire M White
PURPOSE: The experience of working for people with Parkinson's disease (PD) is known to vary substantially and affects the length of time in employment after diagnosis. This study aims at exploring the experience of working for people with PD and to create a model detailing the factors that influence their workplace success. METHOD: A qualitative grounded theoretical approach was used. Seventeen working people with PD were selected for individual interviews which were conducted sequentially...
May 10, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28465112/self-management-support-programs-for-persons-with-parkinson-s-disease-an-integrative-review
#17
REVIEW
Dorothy Kessler, Clare Liddy
OBJECTIVE: To identify the characteristics of self-management programs for persons with Parkinson's disease and the evidence for their effectiveness. METHODS: An integrative literature review was conducted. Studies describing the provision or outcomes of self-management interventions for persons with Parkinson's disease and published in English were included. Two reviewers independently screened and evaluated articles. Interventions were described and compared, and evidence was presented using The Traffic Lighting system...
April 17, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28459694/automatic-assessment-of-a-rollator-user-s-condition-during-rehabilitation-using-the-i-walker-platform
#18
Joaquin Ballesteros, Cristina Urdiales, Antonio B Martinez, Marina Tirado Reyes
Patient condition during rehabilitation has been traditionally assessed using clinical scales. These scales typically require the patient and/or the clinician to rate a number of condition related items to obtain a final score. This is a timeconsuming task, specially if a large number of patients is involved. Furthermore, during rehabilitation, user condition is expected to change steadily in time, so assessment may require to run these scales several times to each user. To save time, much effort has been focused on developing clinical scales that require little time to be completed...
April 25, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28445854/balance-training-in-individuals-with-parkinson-s-disease-therapist-supervised-vs-home-based-exercise-programme
#19
Elizabeth Maria Atterbury, Karen Estelle Welman
BACKGROUND: Poor locomotion and balance in Parkinson's disease (PD) often diminishes independence. Accordingly, gait is considered one of the most relevant rehabilitation outcomes, and home-based balance exercises might be a viable mode of exercise delivery for individuals with PD. However, research on PD interventions rarely indicate best practices to deliver exercises. Therefore, this study endeavoured to compare the efficacy of a home-based and therapist-supervised balance programme on gait parameters, dynamic balance, balance confidence and motivation in individuals diagnosed with PD...
April 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28441826/-a-childhood-onset-rapid-onset-dystonia-parkinsonism-family-with-atp1a3-gene-mutation-and-literatures-review
#20
C L Zhang, F Yin, F He, N Gai, Z Q Shi, J Peng
Objective: To explore clinical characteristics, treatment, and prognosis of a family with childhood-onset rapid-onset dystonia parkinsonism (RDP) caused by ATP1A3 gene mutation and review literatures. Method: The clinical data of a RDP child, his brother and mother had been analyzed retrospectively. This family was admitted to Xiangya Hospital in January 2016. DNA samples were analyzed by the next-generation sequencing and confirmed by Sanger sequencing. Related literature from PubMed, Online Mendelian Inheritance in Man (OMIM), CNKI and Wanfang databases to date (up to October 2016) with"Rapid-onset dystonia-parkinsonism"RDP"DYT12" as key words was reviewed...
April 2, 2017: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
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