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Anaesthesia for young children

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https://www.readbyqxmd.com/read/29120939/clinical-signs-and-electroencephalographic-patterns-of-emergence-from-sevoflurane-anaesthesia-in-children-an-observational-study
#1
Laura Cornelissen, Carolina Donado, Johanna M Lee, Norah E Liang, Ian Mills, Andrea Tou, Aykut Bilge, Charles B Berde
BACKGROUND: Few studies have systematically described relationships between clinical-behavioural signs, electroencephalographic (EEG) patterns and age during emergence from anaesthesia in young children. OBJECTIVE: To identify the relationships between end-tidal sevoflurane (ETsevoflurane) concentration, age and frontal EEG spectral properties in predicting recovery of clinical-behavioural signs during emergence from sevoflurane in children 0 to 3 years of age, with and without exposure to nitrous oxide...
November 8, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28969310/what-do-recent-human-studies-tell-us-about-the-association-between-anaesthesia-in-young-children-and-neurodevelopmental-outcomes
#2
J D O'Leary, D O Warner
Anaesthetic and sedative drugs transiently disrupt normal neural activity to facilitate healthcare procedures in children, but they can also cause long-term brain injury in experimental animal models. The US Food and Drug Administration (FDA) has recently advised that repeated or lengthy exposures to anaesthetic and sedative drugs prior to 3 yr of age have the potential to harm the development of children's brains and added warnings to these drug labels. Paediatric anaesthesia toxicity could represent a significant public health issue, and concern about this potential injury in children has become an important issue for families, paediatric clinicians and healthcare regulators...
September 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28947504/medical-and-bioethical-considerations-in-elective-cochlear-implant-array-removal
#3
Maryanna S Owoc, Elliott D Kozin, Aaron Remenschneider, Maria J Duarte, Ariel Edward Hight, Marjorie Clay, Susanna E Meyer, Daniel J Lee, Selena Briggs
OBJECTIVE: Cochlear explantation for purely elective (e.g. psychological and emotional) reasons is not well studied. Herein, we aim to provide data and expert commentary about elective cochlear implant (CI) removal that may help to guide clinical decision-making and formulate guidelines related to CI explantation. DATA SOURCES: We address these objectives via three approaches: case report of a patient who desired elective CI removal; review of literature and expert discussion by surgeon, audiologist, bioethicist, CI user and member of Deaf community...
September 25, 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28855231/inequalities-in-the-dental-health-needs-and-access-to-dental-services-among-looked-after-children-in-scotland-a-population-data-linkage-study
#4
Alex D McMahon, Lawrie Elliott, Lorna Md Macpherson, Katharine H Sharpe, Graham Connelly, Ian Milligan, Philip Wilson, David Clark, Albert King, Rachael Wood, David I Conway
BACKGROUND: There is limited evidence on the health needs and service access among children and young people who are looked after by the state. The aim of this study was to compare dental treatment needs and access to dental services (as an exemplar of wider health and well-being concerns) among children and young people who are looked after with the general child population. METHODS: Population data linkage study utilising national datasets of social work referrals for 'looked after' placements, the Scottish census of children in local authority schools, and national health service's dental health and service datasets...
August 30, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28684927/immediate-postoperative-pain-and-recovery-time-after-pulpotomy-performed-under-general-anaesthesia-in-young-children
#5
Sultan Keles, Ozlem Kocaturk
BACKGROUND: The aim of this retrospective study was to compare immediate postoperative pain scores and need for rescue analgesia in children who underwent pulpotomies and restorative treatment and those who underwent restorative treatment only, all under general anaesthesia. METHODS: Ninety patients aged between 3 and 7 years who underwent full mouth dental rehabilitation under general anaesthesia were enrolled in the study and reviewed. The experimental group included patients who were treated with at least one pulpotomy, and the control group was treated with dental fillings only...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/28540807/technical-aspects-of-osteoid-osteoma-ablation-in-children-using-mr-guided-high-intensity-focussed-ultrasound
#6
Pavel S Yarmolenko, Avinash Eranki, Ari Partanen, Haydar Celik, AeRang Kim, Matthew Oetgen, Viktoriya Beskin, Domiciano Santos, Janish Patel, Peter C W Kim, Karun Sharma
BACKGROUND: Osteoid osteoma (OO) is a painful bone tumour occurring in children and young adults. Magnetic resonance imaging-guided high intensity focussed ultrasound (MR-HIFU) allows non-invasive treatment without ionising radiation exposure, in contrast to the current standard of care treatment with radiofrequency ablation (RFA). This report describes technical aspects of MR-HIFU ablation in the first 8 paediatric OO patients treated in a safety and feasibility clinical trial (total enrolment of up to 12 patients)...
April 24, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28474809/use-of-anesthetics-in-young-children-consensus-statement-of-the-european-society-of-anaesthesiology-esa-the-european-society-for-paediatric-anaesthesiology-espa-the-european-association-of-cardiothoracic-anaesthesiology-eacta-and-the-european-safe-tots-anaesthesia
#7
EDITORIAL
https://www.readbyqxmd.com/read/28462639/can-laparoscopy-be-part-of-a-paediatric-surgery-outreach-service
#8
R Peeraully, R Hill, D Colliver, A Williams, S Motiwale, B Davies
INTRODUCTION The aim of this study was to assess the outreach laparoscopic service delivered by four paediatric surgeons to a district general hospital (DGH). METHODS A retrospective review was carried out of all laparoscopic procedures performed in a single DGH between January 2004 and November 2014 by the four paediatric surgeons providing the outreach service. All operations were identified from the electronic theatre system and archived correspondence. Demographic and clinical details were obtained from contemporaneous records...
May 2017: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/28358287/follow-up-of-children-s-oral-health-related-quality-of-life-after-dental-general-anaesthesia-treatment
#9
Biruté Jankauskiené, Jorma I Virtanen, Julija Narbutaité
OBJECTIVE: Our aim was to analyze longitudinally the impact of young children's dental general anaesthesia (DGA) treatment on their OHRQoL and to determine their post-operative oral health status at the six-month follow-up together with parental ratings of their children's oral health. MATERIAL AND METHODS: We conducted a prospective follow-up study of OHRQoL among Lithuanian child patients treated under general anaesthesia (n = 144). The study consisted of clinical dental examinations performed by two examiners at the time of DGA and at the six-month recall, along with OHRQoL surveys and data collected from the patients' files...
May 2017: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/28095847/the-biomedical-piglet-establishing-reference-intervals-for-haematology-and-clinical-chemistry-parameters-of-two-age-groups-with-and-without-iron-supplementation
#10
Domenico Ventrella, Francesco Dondi, Francesca Barone, Federica Serafini, Alberto Elmi, Massimo Giunti, Noemi Romagnoli, Monica Forni, Maria L Bacci
BACKGROUND: The similarities between swine and humans in physiological and genomic patterns, and the great correlation in size and anatomy, make pigs extremely useful in preclinical studies. New-born piglets can represent a model for congenital and genetic diseases in new-born children. It is known that piglets may have significant differences in clinicopathological results compared to adult pigs. Therefore, adult laboratory reference intervals cannot be applied to piglets. The aim of this study was to compare haematological and chemical variables in piglets of two ages and determinate age-related reference intervals for commercial hybrid young pigs...
January 17, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28005766/three-dimensional-handheld-scanning-to-quantify-head-shape-changes-in-spring-assisted-surgery-for-sagittal-craniosynostosis
#11
Maik Tenhagen, Jan L Bruse, Naiara Rodriguez-Florez, Freida Angullia, Alessandro Borghi, Maarten J Koudstaal, Silvia Schievano, Owase Jeelani, David Dunaway
Three-dimensional (3D) imaging is an important tool for diagnostics, surgical planning, and evaluation of surgical outcomes in craniofacial procedures. Gold standard for acquiring 3D imaging is computed tomography that entails ionizing radiations and, in young children, a general anaesthesia. Three-dimensional photographic imaging is an alternative method to assess patients who have undergone calvarial reconstructive surgery. The aim of this study was to assess the utility of 3D handheld scanning photography in a cohort of patients who underwent spring-assisted correction surgery for scaphocephaly...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27684707/development-of-a-decision-aid-for-children-faced-with-the-decision-to-undergo-dental-treatment-with-sedation-or-general-anaesthesia
#12
Joe Hulin, Sarah R Baker, Zoe Marshman, Sondos Albadri, Helen D Rodd
BACKGROUND: Decision aids are tools used to help individuals faced with difficult healthcare decisions. They help patients further understand the treatment options available and encourage the sharing of information between patients and clinicians. AIM: To develop a decision aid for young patients faced with the decision to undergo dental treatment with inhalation sedation, intravenous sedation, or general anaesthesia (GA). DESIGN: Qualitative interviews with dental patients (aged 10-16 years), and their parents/guardians were used to inform the content of a draft decision aid...
September 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/27604388/high-dose-methylprednisolone-and-endothelial-glycocalyx-in-paediatric-heart-surgery
#13
E Pesonen, J Keski-Nisula, S Andersson, R Palo, J Salminen, P K Suominen
BACKGROUND: Corticosteroids are used in paediatric heart surgery to attenuate systemic inflammatory response. Glycocalyx regulates vascular permeability, shear stress and cell adhesion on the endothelium. Syndecan-1 serves as a biomarker of glycocalyx degradation. Hydrocortisone decreased endothelial glycocalyx degradation in an experimental model. Our hypothesis was that high-dose methylprednisolone decreases glycocalyx degradation as measured by plasma sydecan-1 concentration in children undergoing cardiac surgery...
November 2016: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/27388563/the-microbiota-in-bronchoalveolar-lavage-from-young-children-with-chronic-lung-disease-includes-taxa-present-in-both-the-oropharynx-and-nasopharynx
#14
COMPARATIVE STUDY
R L Marsh, M Kaestli, A B Chang, M J Binks, C E Pope, L R Hoffman, H C Smith-Vaughan
BACKGROUND: Invasive methods requiring general anaesthesia are needed to sample the lung microbiota in young children who do not expectorate. This poses substantial challenges to longitudinal study of paediatric airway microbiota. Non-invasive upper airway sampling is an alternative method for monitoring airway microbiota; however, there are limited data describing the relationship of such results with lung microbiota in young children. In this study, we compared the upper and lower airway microbiota in young children to determine whether non-invasive upper airway sampling procedures provide a reliable measure of either lung microbiota or clinically defined differences...
July 7, 2016: Microbiome
https://www.readbyqxmd.com/read/27377111/the-need-for-repeated-dental-care-under-general-anaesthesia-in-children
#15
K Bücher, K Rothmaier, R Hickel, R Heinrich-Weltzien, J Kühnisch
AIM: Though the use of advanced behaviour management may facilitate dental treatment in children, some patients still require comprehensive care under general anaesthesia (GA). This is especially true for young children and/or medically compromised children. Thus, this study aimed to provide information about children undergoing GA with regard to age, sex and medical conditions (ICD-10), repeated treatments, dental procedures and recall. MATERIALS AND METHODS: A total of 464 medically compromised children treated under GA in a dental university clinic between 2004 and 2012 were included...
June 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27166452/-dental-treatment-under-general-anaesthesia-in-young-children
#16
REVIEW
M A E-M Oomens, L H D Booij, J A Baart
General anaesthesia in children younger than 4 years of age can cause brain damage with cognitive and behavioral problems as a result. The chance of these side effects is small, but increases with prolonged duration of the anaesthesia or when the general anaesthesia is provided more frequently. It goes without saying that the indication for anaesthesia should be very strictly set. In order to reduce the chance of damage, the anaesthesia itself should be performed in consultation between the anaesthesiologist and care provider, according to a set protocol...
May 2016: Nederlands Tijdschrift Voor Tandheelkunde
https://www.readbyqxmd.com/read/27054906/pediatric-anesthesia-and-neurotoxicity-can-findings-be-translated-from-animals-to-humans
#17
Nicola Disma, Tom G Hansen
Many studies have demonstrated a neurodegenerative effect of anesthetic drugs in cubs and young animals, raising the concern that similar effects can happen in children, and that the administration of anesthesia in young children undergoing surgical or diagnostic procedures may cause long-term neurocognitive impairment. Thus, several epidemiological studies have been performed with the aim to find a possible association between early anesthesia exposure and poor long-term outcome, like learning disabilities or worse school grading and two prospective trials are currently running, the GAS and the PANDA study...
July 2016: Minerva Anestesiologica
https://www.readbyqxmd.com/read/26914597/pulsed-dye-laser-treatment-of-capillary-malformations-in-infants-at-2-weekly-versus-3-monthly-intervals-reducing-the-need-for-general-anaesthesia
#18
Bonnie C Swan, Susan J Robertson, Alana Tuxen, Ellen Ma, Leona Yip, Lena Ly, Linda Bingham, Andrew Davidson, Philip Bekhor
Capillary malformations (CM) cause significant psychosocial complications. Pulsed dye laser (PDL) treatment at 6-12-weekly intervals under general anaesthesia (GA) commencing in infants at 6 months of age remains the standard of care in order to achieve maximal improvement prior to school age. The safety of repeated GA in children is controversial. Shortening the time between treatments increases the number that can be delivered prior to 6 months of age, thus reducing the number of subsequent treatments needed under GA...
August 2017: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/26895372/the-use-of-ultrasound-guidance-for-perioperative-neuraxial-and-peripheral-nerve-blocks-in-children
#19
REVIEW
Joanne Guay, Santhanam Suresh, Sandra Kopp
BACKGROUND: The use of ultrasound guidance for regional anaesthesia has become popular over the past two decades. However, it is not recognized by all experts as an essential tool. The cost of an ultrasound machine is substantially higher than the cost of other tools such as a nerve stimulator. OBJECTIVES: To determine whether ultrasound guidance offers any clinical advantage when neuraxial and peripheral nerve blocks are performed in children in terms of increasing the success rate or decreasing the rate of complications...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/26865130/emergence-delirium-or-pain-after-anaesthesia-how-to-distinguish-between-the-two-in-young-children-a-retrospective-analysis-of-observational-studies
#20
M Somaini, T Engelhardt, R Fumagalli, P M Ingelmo
BACKGROUND: Early postoperative negative behaviour in preschool children after general anaesthesia is a common problem. The distinction between emergence delirium (ED) and pain is difficult, but management differs between the two. The aim of the current analysis was to identify individual observational variables that can be used to diagnose ED and allow distinction from postoperative pain. METHODS: This retrospective analysis of data from three previous prospective observational studies included children undergoing general anaesthesia for elective adeno-tonsillectomy, sub-umbilical surgery, and MRI scanning...
March 2016: British Journal of Anaesthesia
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