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https://www.readbyqxmd.com/read/29677691/iodine-status-of-pregnant-women-from-a-coastal-brazilian-state-after-the-reduction-in-recommended-iodine-concentration-in-table-salt-according-to-governmental-requirements
#1
Débora Ayres Saraiva, Nathalie Anne de Oliveira E Silva de Morais, Carolina Martins Corcino, Tatiana Martins Benvenuto Louro Berbara, Annie Schtscherbyna, Mischelle Santos, Heron Botelho, Mario Vaisman, Patrícia de Fátima Dos Santos Teixeira
OBJECTIVE: To evaluate iodine status among pregnant women from a coastal state after Brazilian governmental resolution reducing iodine concentrations in table salt. Secondarily, we correlated urinary iodine concentration (UIC) with thyroid volume and hormones. METHODS: Inductively coupled plasma mass spectrometry was used to assess UIC from 629 samples of 244 first trimester pregnant women. Thyroid ultrasound, serum thyroglobulin, thyrotropin, free thyroxine, and antithyroid antibodies were measured as iodine concentrations on samples of table salt from patient's home...
February 14, 2018: Nutrition
https://www.readbyqxmd.com/read/29677624/metal-free-oxidative-esterification-of-benzylated-monosaccharides
#2
Tchambaga Camara, Abed Bil, Vincent Chagnault
Methyl glyconates have been attracting considerable attention as intermediates for the preparation of aryl C-glycosides, polyphenolic products, aliphatic polyesters, SGLT2 inhibitors, antibiotics etc … In view of the interest in those compounds, we report herein our work on the synthesis of methyl glyconates using an oxidative esterification carried out by molecular iodine. This reaction is catalyzed by non-toxic K4 Fe(CN)6 that releases a small amount of cyanide ion into the reaction mixture. Four benzylated carbohydrates which contain a hemiacetalic functional group have been tested successfully...
April 12, 2018: Carbohydrate Research
https://www.readbyqxmd.com/read/29677112/iodine-deficiency-in-a-study-population-of-norwegian-pregnant-women-results-from-the-little-in-norway-study-lin
#3
Lisbeth Dahl, Maria Wik Markhus, Perla Vanessa Roldan Sanchez, Vibeke Moe, Lars Smith, Helle Margrete Meltzer, Marian Kjellevold
Iodine sufficiency is particularly important in pregnancy, where median urinary iodine concentration (UIC) in the range of 150⁻250 µg/L indicates adequate iodine status. The aims of this study were to determine UIC and assess if dietary and maternal characteristics influence the iodine status in pregnant Norwegian women. The study comprises a cross-sectional population-based prospective cohort of pregnant women (Little in Norway (LiN)). Median UIC in 954 urine samples was 85 µg/L and 78...
April 20, 2018: Nutrients
https://www.readbyqxmd.com/read/29675658/iodine-concentration-a-new-important-characteristic-of-the-spot-sign-that-predicts-haematoma-expansion
#4
Fan Fu, Shengjun Sun, Liping Liu, Jianying Li, Yaping Su, Yingying Li
OBJECTIVES: The computed tomography angiography (CTA) spot sign is a validated predictor of haematoma expansion (HE) in spontaneous intracerebral haemorrhage (SICH). We investigated whether defining the iodine concentration (IC) inside the spot sign and the haematoma on Gemstone spectral imaging (GSI) would improve its sensitivity and specificity for predicting HE. METHODS: From 2014 to 2016, we prospectively enrolled 65 SICH patients who underwent single-phase spectral CTA within 6 h...
April 19, 2018: European Radiology
https://www.readbyqxmd.com/read/29675159/the-mechanism-of-directed-ni-ii-catalyzed-c-h-iodination-with-molecular-iodine
#5
Brandon E Haines, Jin-Quan Yu, Djamaladdin G Musaev
The density functional theory method is used to elucidate the elementary steps of Ni(ii)-catalyzed C(sp2 )-H iodination with I2 and substrates bearing N , N '-bidentate directing centers, amide-oxazoline (AO) and 8-aminoquinoline (AQ). The relative stability of the lowest energy high- and low-spin electronic states of the catalyst and intermediates is found to be an important factor for all of the steps in the reaction. As a result, two-state reactivity for these systems is reported, where the reaction is initiated on the triplet surface and generates a high energy singlet nickelacycle...
February 7, 2018: Chemical Science
https://www.readbyqxmd.com/read/29674804/three-material-decomposition-in-multi-energy-ct-impact-of-prior-information-on-noise-and-bias
#6
Liqiang Ren, Cynthia H McCollough, Lifeng Yu
In order to perform material decomposition for a three-material mixture, dual-energy CT (DECT) has to incorporate an additional condition, typically the prior information related to certain physical constraints such as volume or mass conservation. With the introduction of photon-counting CT and other multi-energy CT (MECT) platform, more than 2 energy bins can be simultaneously acquired, which in principle can solve a three-material problem without the need of additional prior information. The purpose of this work was to investigate the impact of prior information on noise and bias properties of three-material decomposition in both DECT and MECT, and to evaluate if the prior information is still needed in MECT...
March 2018: Proceedings of SPIE
https://www.readbyqxmd.com/read/29674061/two-dimensional-weak-anion-exchange-chromatography-gel-electrophoresis-separations-coupling-to-inductively-coupled-plasma-mass-spectrometry-strategy-for-analysis-of-metalloproteins
#7
Xueting Yan, Bin He, Dingyi Wang, Ligang Hu, Lihong Liu, Chunyang Liao, Guibin Jiang
A two-dimensional (2-D, weak anion exchange chromatography-gel electrophoresis, WAX-GE) separations coupling to inductively coupled plasma mass spectrometry (ICP-MS) strategy was developed for efficient tracking of metalloproteins. Samples were fractionized with the primary dimension (WAX) and the collected fractions were subsequently subjected to the secondary dimension (GE) and finally detected with ICP-MS. The metalloproteins of interest from the secondary dimension were online split and collected for further manipulation...
July 1, 2018: Talanta
https://www.readbyqxmd.com/read/29673971/changes-in-trophoblasts-gene-expression-in-response-to-perchlorate-exposition
#8
De la Peña Sol, Santiago-Roque Isela, Olivo-Vidal Zendy, Navarro-Meza Mónica, Xochihua-Rosas Irene, Arroyo-Helguera Omar
Contaminated water with chlorates is a public health problem associated with iodine deficiency. Epidemiological evidence shows that iodine deficiency is a risk factor for preeclampsia (PE). In this study we use human BeWo trophoblast cells exposed to perchlorate (KClO4 ) and changes in gene expression were analyzed by microarrays, quantitative RT-PCR (qRT-PCR) and immunoblot. The microarray analysis identified 48 transcripts up-regulated and 112 down-regulated in comparison with non-exposed trophoblast. The qRT-PCR analysis confirmed changes in GAS7, PKP2, Emilin, Dynatic 3, protocadherins 11, 15, gamma A12, EGFR, SAFB1, ACE2, ANXA2, Apoliprotein E, SREBF1, and C/EBP-β...
April 16, 2018: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/29673811/endovascular-aortic-repair-follow-up-protocol-based-on-contrast-enhanced-ultrasound-is-safe-and-effective
#9
Emiliano Chisci, Linda Harris, Azzurra Guidotti, Angelica Pecchioli, Clara Pigozzi, Enrico Barbanti, Leonardo Ercolini, Stefano Michelagnoli
OBJECTIVES: The aim of this study was to define the safety and effectiveness of a contrast enhanced ultrasound (CEUS) based follow up for endovascular aortic repair (EVAR) surveillance at a mid-term period (4 years). METHODS: At the tertiary referral centre EVAR surveillance was based on plain abdominal radiograph and duplex ultrasound (CDU), with computed tomography angiography (CTA) reserved for any non-diagnostic imaging during the period 1999-2011 (Group A)...
April 17, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29672887/young-age-is-associated-with-increased-rates-of-residual-recurrent-pediatric-differentiated-thyroid-carcinoma
#10
Sarah Hampson, Derek Stephens, Jonathan D Wasserman
OBJECTIVE: Differentiated thyroid carcinoma is rare in young children. There are conflicting data as to whether disease in this age group differs from that in adolescents and specifically, if it is more aggressive. Current practice guidelines do not differentiate treatment between these groups, but speculate that differences may exist. We sought to compare clinical features, treatment and outcomes between children (<12 years) and adolescents (12-18 years) with thyroid nodules and thyroid malignancy over a 20 year period...
April 19, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29672267/point-of-care-creatinine-testing-for-kidney-function-measurement-prior-to-contrast-enhanced-diagnostic-imaging-evaluation-of-the-performance-of-three-systems-for-clinical-utility
#11
Beverly Snaith, Martine A Harris, Bethany Shinkins, Marieke Jordaan, Michael Messenger, Andrew Lewington
BACKGROUND: Acute kidney injury (AKI) can occur rarely in patients exposed to iodinated contrast and result in contrast-induced AKI (CI-AKI). A key risk factor is the presence of preexisting chronic kidney disease (CKD); therefore, it is important to assess patient risk and obtain kidney function measurement prior to administration. Point-of-care (PoC) testing provides an alternative strategy but there remains uncertainty, with respect to diagnostic accuracy and clinical utility. METHODS: A device study compared three PoC analysers (Nova StatSensor, Abbott i-STAT and Radiometer ABL800 FLEX) with a reference laboratory standard (Roche Cobas 8000 series, enzymatic creatinine)...
April 19, 2018: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/29671774/regression-analysis-to-identify-factors-associated-with-household-salt-iodine-content-at-the-sub-national-level-in-bangladesh-india-ghana-and-senegal
#12
Jacky Knowles, Roland Kupka, Sam Dumble, Greg S Garrett, Chandrakant S Pandav, Kapil Yadav, Baitun Nahar, Ndeye Khady Touré, Esi Foriwa Amoaful, Jonathan Gorstein
Regression analyses of data from stratified, cluster sample, household iodine surveys in Bangladesh, India, Ghana and Senegal were conducted to identify factors associated with household access to adequately iodised salt. For all countries, in single variable analyses, household salt iodine was significantly different ( p < 0.05) between strata (geographic areas with representative data, defined by survey design), and significantly higher ( p < 0.05) among households: with better living standard scores, where the respondent knew about iodised salt and/or looked for iodised salt at purchase, using salt bought in a sealed package, or using refined grain salt...
April 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29671571/nitrogen-rich-porous-polymers-for-carbon-dioxide-and-iodine-sequestration-for-environmental-remediation
#13
Yomna H Abdelmoaty, Tsemre-Dingel Tessema, Fatema Akthar Choudhury, Oussama M El-Kadri, Hani M El-Kaderi
The use of fossil fuels for energy production is accompanied by carbon dioxide release into the environment causing catastrophic climate changes. Meanwhile, replacing fossil fuels with carbon-free nuclear energy has the potential to release radioactive iodine during nuclear waste processing and in case of a nuclear accident. Therefore, developing efficient adsorbents for carbon dioxide and iodine capture is of great importance. Two nitrogen-rich porous polymers (NRPPs) derived from 4-bis-(2,4-diamino-1,3,5,-triazine)-benzene building block were prepared and tested for use in CO2 and I2 capture...
April 19, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29670217/bacterial-derived-exopolysaccharides-enhance-antifungal-drug-tolerance-in-a-cross-kingdom-oral-biofilm
#14
Dongyeop Kim, Yuan Liu, Raphael I Benhamou, Hiram Sanchez, Áurea Simón-Soro, Yong Li, Geelsu Hwang, Micha Fridman, David R Andes, Hyun Koo
Fungal-bacterial interactions generate unique biofilms that cause many infections in humans. Candida albicans interact with Streptococcus mutans in dental biofilms associated with severe childhood tooth-decay, a prevalent pediatric oral disease. Current modalities are ineffective and primarily based on antimicrobial monotherapies despite the polymicrobial nature of the infection. Here, we show that the combination of clinically used topical antifungal fluconazole with povidone iodine (PI) can completely suppress C...
April 18, 2018: ISME Journal
https://www.readbyqxmd.com/read/29669614/potassium-iodate-levels-in-processed-edible-salts-available-in-retail-shops-throughout-kenya-2013
#15
Gerald Gikonyo Githinji, Nancy Njine, John Njihia, John Mwihia, James Ransom
OBJECTIVE: Iodine-deficiency disorders, due to insufficiency of iodine in the diet, are a global public health problem. The Kenyan Food, Drugs and Chemical Substances Act stipulates that processed retail-available edible salts contain 50-84 mg of potassium iodate (KIO3) per kilogram of salt. The present study determined the status of KIO3 levels in commercial salts, for public health action.Design/Setting/SubjectsAs part of the Kenya Demographic and Health Survey 2013, field workers collected salt samples from seven different local manufacturers/packers across eight regions of the country and sent them to the National Public Health Laboratory (NPHL) for KIO3 titration analysis...
April 19, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29666905/balloon-occluded-carbon-dioxide-gas-angiography-for-internal-iliac-arteriography-and-intervention
#16
Mitsuhiro Kishino, Shuichiro Nakaminato, Yoshio Kitazume, Naoyuki Miyasaka, Toshifumi Kudo, Yukihisa Saida, Ukihide Tateishi
INTRODUCTION: The usefulness of carbon dioxide (CO2 ) gas digital subtraction angiography (DSA) has been reported for patients with renal insufficiency and allergy to iodinated contrast agents. However, CO2 gas cannot replace the iodinated contrast agent in all cases owing to some disadvantages. We describe balloon-occluded CO2 DSA (B-CO2 DSA) as an improved CO2 DSA procedure for interventions in the internal iliac artery (IIA) region and compare the quality of images obtained using conventional CO2 DSA and B-CO2 DSA...
April 17, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29666785/risk-evaluation-of-endoscopic-retrograde-cholangiopancreatography-related-contrast-media-allergic-like-reaction-a-single-centre-experience
#17
Félix Trottier-Tellier, Laurence Harvey, Jean-Daniel Baillargeon
Background and Aims. Few cases of endoscopic retrograde cholangiopancreatography- (ERCP-) related contrast media (CM) adverse reactions have been reported in the current literature. There is a lack of standardisation in practice regarding premedication prophylaxis for at-risk patients undergoing ERCP and there are few data to guide the practitioners. Our goal is to evaluate the risk of CM adverse reaction in a group of patients with a past history of allergic-like reaction to iodine product undergoing ERCP...
2018: Canadian Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29665575/role-of-fungal-laccase-in-iodide-oxidation-in-soils
#18
Reiko Nihei, Mizuki Usami, Taro Taguchi, Seigo Amachi
Previously, we hypothesized that microbial laccase oxidizes iodide (I- ) in soils to molecular iodine (I2 ) or hypoiodous acid (HIO), both of which are easily incorporated into natural soil organic matter, and thus plays a role in iodine sorption on soils. In this study, soil iodide oxidase activity was determined by a colorimetric assay to evaluate if laccase is responsible for iodide oxidation in soils. Three types of Japanese soil showed significant iodide oxidase activities (0.751-2.87 mU g soil-1 ) at pH 4...
April 14, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29665550/polyfluorinated-iodine-alkanes-regulated-distinct-breast-cancer-cell-progression-through-binding-with-estrogen-receptor-alpha-or-beta-isoforms
#19
Wenting Song, Qian S Liu, Zhendong Sun, Xiaoxi Yang, Qunfang Zhou, Guibin Jiang
Polyfluorinated iodine alkanes (PFIs) are a kind of emerging chemicals with endocrine disrupting effects. Based on the different binding preferences of PFIs to estrogen receptor alpha and beta isoforms (ERα and β), two representative PFIs, dodecafluoro-1,6-diiodohexane (PFHxDI) and tridecafluorohexyl iodide (PFHxI), were selected to evaluate their effects on the proliferation of two kinds of breast cancer cells with different ERα/β expression levels, MCF-7 and T47D. The cell viability assay showed PFHxDI could cause higher cellular toxicity than did PFHxI in both MCF-7 and T47D...
April 14, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29665187/redox-responsive-covalent-organic-nanosheets-from-viologens-and-calix-4-arene-for-iodine-and-toxic-dye-capture
#20
Tina Skorjanc, Dinesh Shetty, Sudhir Sharma, Jesus Raya, Hassan Traboulsi, Dong-Suk Han, Jayesh Lalla, Ryan Newlon, Ramesh Jagannathan, Serdal Kirmizialtin, John-Carl Olsen, Ali Trabolsi
Owing to their chemical and thermal stabilities, high uptake capacities, and easy recyclability, covalent organic polymers (COPs) have shown promise as pollutant sponges. Here, we describe the use of diazo coupling to synthesize two cationic COPs, COP1++ and COP2++, that incorporate a viologen-based molecular switch and an organic macrocycle, calix[4]arene. Both COPs form nanosheets with height profiles of 6.00 and 8.00 nm, respectively, based on AFM measurements. The sheets remain morphologically intact upon one- or two-electron reductions of their viologen subunits...
April 17, 2018: Chemistry: a European Journal
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