Limin Lang, Jisong Zheng, Shuyi Liang, Fenglin Zhang, Yiming Fu, Kaixin Deng, Fan Li, Xiaohua Yang, Junfeng Wang, Yuexiang Luo, Shilei Zhang, Xiaotong Zhu, Lina Wang, Ping Gao, Canjun Zhu, Gang Shu, Qianyun Xi, Yongliang Zhang, Qingyan Jiang, Songbo Wang
Mammary fat plays a profound role in the postnatal development of mammary glands. However, the specific types (white, brown, or beige) of adipocytes in mammary fat and their potential regulatory effects on modulating mammary gland development remain poorly understood. This study aimed to investigate the role of the browning of mammary fat on pubertal mammary gland development and explore the underlying mechanisms. Thus, the mammary gland development and the serum lipid profile were evaluated in mice treated with CL316243, a β3-adrenoceptor agonist, to induce mammary fat browning...
November 10, 2023: International Journal of Molecular Sciences