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https://www.readbyqxmd.com/read/28183593/structure-and-mechanical-behavior-of-human-hair
#1
Yang Yu, Wen Yang, Bin Wang, Marc André Meyers
The understanding of the mechanical behavior of hair under various conditions broadens our knowledge in biological materials science and contributes to the cosmetic industry. The hierarchical organization of hair is studied from the intermediate filament to the structural levels. The effects of strain rate, relative humidity, and temperature are evaluated. Hair exhibits a high tensile strength, 150-270MPa, which is significantly dependent on strain rate and humidity. The strain-rate sensitivity, approximately 0...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28169594/keratin-hydrogel-enhances-in-vivo-skeletal-muscle-function-in-a-rat-model-of-volumetric-muscle-loss
#2
Juliana A Passipieri, Hannah B Baker, Mevan Siriwardane, Mary Ellenburg, Manasi Vadhavkar, Justin M Saul, Seth Tomblyn, Luke Burnett, George Joseph Christ
Volumetric Muscle Loss (VML) injuries exceed the considerable intrinsic regenerative capacity of skeletal muscle resulting in permanent functional and cosmetic deficits. VML and VML-like injuries occur in military and civilian populations, due to trauma and surgery as well as a host of congenital and acquired diseases/syndromes. Current therapeutic options are limited, and new approaches are needed for more complete functional regeneration of muscle. A potential solution is human hair derived keratin (KN) biomaterials that may have significant potential for regenerative therapy...
February 7, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28164425/the-cosmetic-and-dermatological-potential-of-keratin-hydrolysate
#3
Pavel Mokrejs, Matous Hutta, Jana Pavlackova, Pavlina Egner, Lubomir Benicek
BACKGROUND: Although keratin hydrolysates have become established as standard components in hair and nail cosmetics, studies on the moisturizing effects of keratin hydrolysates do not appear among contemporary literature. OBJECTIVES: To test if adding keratin hydrolysate into an ointment base increases hydration of the skin and improves skin barrier function, or diminishes trans-epidermal water loss. METHODS: Formulations were prepared containing 2%, 4%, and 6% keratin hydrolysates (based on weight of the ointment base)...
February 6, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28142293/a-case-report-of-coup-de-sabre-patient-with-hair-transplantation
#4
Yeqin Dai, Ai-E Xu, Junhua He
BACKGROUND: Treatment of coup de sabre must remain conservative until the disease is no longer in an active state. When activity has ceased, some operative intervention is safe and effective for the correction of deformity. While hair transplantation showed high survival rates for the correction of cicatricial alopecia, it has rarely reported to be performed for the correction of coup de sabre. OBJECTIVE: To assess the therapeutic possibility of hair transplantation for the correction of coup de sabre...
January 31, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28125532/the-modern-male-rhytidectomy-lessons-learned
#5
Rod J Rohrich, James M Stuzin, Smita Ramanadham, Christopher Costa, Phillip B Dauwe
BACKGROUND: Cosmetic surgery among male patients has become increasingly popular. The face-lift technique is different in male patients, specifically regarding preservation of hair follicles, restoration of a youthful and well appearance, and reduction of the risk of hematoma. METHODS: A retrospective review of a single surgeon's past 20 years of consecutive male rhytidectomies revealed a cohort of 83 patients. A control group was created by random selection of 83 age-matched female rhytidectomy patients during the same period...
February 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28109001/polygonum-multiflorum-radix-extract-protects-human-foreskin-melanocytes-from-oxidative-stress-in-vitro-and-potentiates-hair-follicle-pigmentation-ex-vivo
#6
Peggy Sextius, Richard Betts, Ishak Benkhalifa, Stéphane Commo, Joan Eilstein, Marco Massironi, Ping Wang, Jean-Francois Michelet, Jie Qiu, Xuezhu Tan, Severine Jeulin
OBJECTIVE: To examine the ability of an extract from traditional Chinese medicine, Polygonum multiflorum Radix, to protect melanocyte viability from oxidative stress, a key mechanism in the initiation and progression of hair greying. METHODS: To assess the antioxidant capacity of Polygonum multiflorum Radix extract, primary human foreskin melanocytes were treated with a commercially available Polygonum multiflorum Radix extract added to culture medium and exposed to hydrogen peroxide (H2 O2 ), using intracellular reactive oxygen species concentrations and glutathione/protein ratios as endpoints...
January 20, 2017: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/28098722/prevalence-of-preservatives-across-all-product-types-in-the-contact-allergen-management-program
#7
Kevin M Beene, Andrew Scheman, Dave Severson, Margo J Reeder
BACKGROUND: Preservatives are known causes of allergic contact dermatitis. OBJECTIVE: The aim of this study was to determine the prevalence of preservatives in each product category in the Contact Allergen Management Program and compare prevalence with reported rates of allergic contact dermatitis. METHODS: Contact Allergen Management Program product information was queried based on the 53 approved preservatives for cosmetic products by the European Union and Association of Southeast Asian Nations plus 5 additional preservatives used in US products...
January 2017: Dermatitis
https://www.readbyqxmd.com/read/28042321/pre-vascularization-enhances-therapeutic-effects-of-human-mesenchymal-stem-cell-sheets-in-full-thickness-skin-wound-repair
#8
Lei Chen, Qi Xing, Qiyi Zhai, Mitchell Tahtinen, Fei Zhou, Lili Chen, Yingbin Xu, Shaohai Qi, Feng Zhao
Split thickness skin graft (STSG) implantation is one of the standard therapies for full thickness wound repair when full thickness autologous skin grafts (FTG) or skin flap transplants are inapplicable. Combined transplantation of STSG with dermal substitute could enhance its therapeutic effects but the results remain unsatisfactory due to insufficient blood supply at early stages, which causes graft necrosis and fibrosis. Human mesenchymal stem cell (hMSC) sheets are capable of accelerating the wound healing process...
2017: Theranostics
https://www.readbyqxmd.com/read/28036072/maternal-exposure-to-domestic-hair-cosmetics-and-occupational-endocrine-disruptors-is-associated-with-a-higher-risk-of-hypospadias-in-the-offspring
#9
Elodie Haraux, Karine Braun, Philippe Buisson, Erwan Stéphan-Blanchard, Camille Devauchelle, Jannick Ricard, Bernard Boudailliez, Pierre Tourneux, Richard Gouron, Karen Chardon
Pregnant women are exposed to various chemical products at home and at work. Some of these products contain endocrine-disrupting chemicals (EDCs) such as cosmetics, pesticides, industrial chemicals, heavy metals, plastics or medications that could alter sexual differentiation and increase the risk of hypospadias. We evaluated maternal occupational and household exposures that could constitute risk factors for hypospadias. From 2011 to 2014, we enrolled 57 full-term newborns with hypospadias and three randomly selected controls per case (162 control newborns), matched for gestational age, from 11 maternity units in Picardy, France...
December 29, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28004257/literature-review-of-cosmetic-procedures-in-men-approaches-and-techniques-are-gender-specific
#10
REVIEW
Brandon E Cohen, Sameer Bashey, Ashley Wysong
The proportion of men receiving non-surgical cosmetic procedures has risen substantially in recent years. Various physiologic, anatomic, and motivational considerations differentiate the treatments for male and female patients. Nevertheless, research regarding approaches to the male cosmetic patient is scarce. We sought to provide an overview and sex-specific discussion of the most popular cosmetic dermatologic procedures pursued by men by conducting a comprehensive literature review pertaining to non-surgical cosmetic procedures in male patients...
December 21, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28003975/preoperative-evaluation-and-outcome-of-corneal-transplantation-for-limbal-dermoids-a-ten-year-follow-up-study
#11
Meng Xin, Yue-Rong Gong, Shan-Hao Jiang, Chun-Hua Dai, Su-Xia Li, Wei-Yun Shi
AIM: To summarize preoperative evaluation and outcome of corneal transplantation for limbal dermoids for ten years. METHODS: Eighty-five patients diagnosed with limbal dermoids and treated with corneal transplantation were analyzed retrospectively. All patients were further divided into two groups according to absence or presence of neovascularization surrounding the dermoids in the corneal stroma. Eighty-two eyes were treated with tumor excision combined with partial lamellar sclerokeratoplasty, and the other three eyes were performed by penetrating keratoplasty...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/27997709/the-role-of-allogenic-keratin-derived-dressing-in-wound-healing-in-a-mouse-model
#12
Marek Konop, Dorota Sulejczak, Joanna Czuwara, Piotr Kosson, Aleksandra Misicka, Aandrzej W Lipkowski, Lidia Rudnicka
: Keratin is an interesting protein needed for wound healing and tissue recovery. We have recently proposed a new, simple and inexpensive method to obtain fur and hair keratin-derived biomaterials suitable for medical application. The aim of the study was to evaluate the role of the fur keratin derived protein (FKDP) dressing in the allogenic full-thickness surgical skin wound model. RESULTS: The data obtained using scanning electron microscopy showed that employed processed biomaterial had higher surface porosity compared to control raw material...
December 20, 2016: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/27918002/hair-care-practices-in-african-american-women-potential-for-allergic-contact-dermatitis
#13
Alicia Stallings, Apra Sood
Allergic contact dermatitis (ACD) is a delayed hypersensitivity reaction that occurs when the skin is re-exposed to a substance to which it was previously sensitized. One significant source of exposure to sensitizing chemicals is through personal grooming and beauty products. While the role of cosmetics and hair-care products in the development of ACD is well-documented, there has been very little literature that specifically addresses the role of hair-care practices of patients with tightly curled hair, such as in patients of African descent, in the development of ACD in this population...
December 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27913787/safety-assessment-of-polyquaternium-22-and-polyquarternium-39-as-used-in-cosmetics
#14
Wilbur Johnson, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, F Alan Andersen
Polyquaternium-22 and polyquaternium-39 are polymers that function as antistatic agents, film formers, and hair fixatives in cosmetic products. These ingredients are being used at concentrations up to 2% (polyquaternium-22, in a rinse-off product) and up to 3% (polyquaternium-39, in rinse-off and leave-on products). The unreacted monomer content of these ingredients was considered low and of no toxicological concern. Limited data showed no skin irritation/sensitization. Although these ingredients were nongenotoxic in bacterial assays, mammalian genotoxicity, carcinogenicity, and reproductive and developmental toxicity data were not available...
November 2016: International Journal of Toxicology
https://www.readbyqxmd.com/read/27913772/safety-assessment-of-formic-acid-and-sodium-formate-as-used-in-cosmetics
#15
Wilbur Johnson, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, F Alan Andersen
Formic acid functions as a fragrance ingredient, preservative, and pH adjuster in cosmetic products, whereas sodium formate functions as a preservative. Because of its acidic properties, formic acid is a dermal and ocular irritant. However, when used as a pH adjuster in cosmetic formulations, formic acid will be neutralized to yield formate salts, for example, sodium formate, thus minimizing safety concerns. Formic acid and sodium formate have been used at concentrations up to 0.2% and 0.34%, respectively, with hair care products accounting for the highest use concentrations of both ingredients...
November 2016: International Journal of Toxicology
https://www.readbyqxmd.com/read/27913771/safety-assessment-of-methyl-glucose-polyethers-and-esters-as-used-in-cosmetics
#16
Wilbur Johnson, Bart Heldreth, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, F Alan Andersen
The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of methyl glucose polyethers and esters which function in cosmetics as skin/hair-conditioning agents, surfactants, or viscosity increasing agents. The esters included in this assessment are mono-, di-, or tricarboxyester substituted methyl glucosides, and the polyethers are mixtures of various chain lengths. The Panel reviewed available animal and clinical data, including the molecular weights, log Kows, and other properties in making its determination of safety on these ingredients...
November 2016: International Journal of Toxicology
https://www.readbyqxmd.com/read/27910904/melanosome-transfer-to-keratinocyte-in-the-chicken-embryonic-skin-is-mediated-by-vesicle-release-associated-with-rho-regulated-membrane-blebbing
#17
Ryosuke Tadokoro, Hidetaka Murai, Ken-Ichiro Sakai, Takahiro Okui, Yasuhiro Yokota, Yoshiko Takahashi
During skin pigmentation in amniotes, melanin synthesized in the melanocyte is transferred to keratinocytes by a particle called the melanosome. Previous studies, mostly using dissociated cultured cells, have proposed several different models that explain how the melanosome transfer is achieved. Here, using a technique that labels the plasma membrane of melanocytes within a three-dimensional system that mimics natural tissues, we have visualized the plasma membrane of melanocytes with EGFP in chicken embryonic skin...
December 2, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27899137/ethnobotanical-survey-of-cosmetic-plants-used-in-marquesas-islands-french-polynesia
#18
Xénia Jost, Jean-Luc Ansel, Gaël Lecellier, Phila Raharivelomanana, Jean-François Butaud
BACKGROUND: Cosmetic plants and their uses have often been neglected in ethnobotanical surveys which focus mainly on plants with medicinal or food uses. Thus, this survey was carried out to specifically investigate cosmetics in a small community and to establish a cosmetopoeia, based on the model of pharmacopoeia for medicinal plants. The geographic spread of the survey covered the Marquesas Islands, one of the five archipelagos of French Polynesia (Pacific Ocean). This archipelago was also recently investigated for its pharmacopoeia...
November 29, 2016: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/27882588/clinical-and-epidemiological-analysis-in-149-cases-of-rhododendrol-induced-leukoderma
#19
Momoko Yoshikawa, Yasuyuki Sumikawa, Tokimasa Hida, Takafumi Kamiya, Kimi Kase, Yasue Ishii-Osai, Junji Kato, Yuji Kan, Shiori Kamiya, Yuki Sato, Toshiharu Yamashita
Rhododendrol-induced leukoderma is an acquired depigmentation that develops mainly at the contact site after repeated use of skin-whitening cosmetics containing rhododendrol. In most cases, cessation of further depigmentation or occurrence of repigmentation is observed after discontinuing the use of cosmetics. However, some patients develop vitiligo vulgaris through the spread of depigmentation into the non-exposed areas. Our study aims to investigate the patient-specific factors that may affect the extent of depigmentation or repigmentation, as well as development of vitiligo vulgaris...
November 24, 2016: Journal of Dermatology
https://www.readbyqxmd.com/read/27802065/a-review-on-laser-and-light-based-therapies-for-alopecia-areata
#20
Stephanie Mlacker, Adam Souhail Aldahan, Brian James Simmons, Vidhi Shah, Colin Andrew McNamara, Sahal Samarkandy, Keyvan Nouri
Alopecia areata is a form of non-scarring alopecia that results from a hyperactive immune response of T cells against hair follicles. Many patients with visible hair loss experience psychological and emotional distress, as a result of their cosmetic disfigurement, and frequently seek treatment. However, existing treatment methods, such as corticosteroids, topical irritants, sensitizing agents, immunosuppressants, and psoralen plus ultraviolet light A may result in various adverse effects and often lack efficacy...
November 1, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
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