keyword
https://read.qxmd.com/read/38649858/a-cost-effectiveness-analysis-of-fluoride-varnish-application-in-preventing-root-caries-in-elderly-persons-a-markov-simulation-study
#21
JOURNAL ARTICLE
Long-Wen Zhu, Rui-Xin Wang, Yu Zhang, Jing-Yu Zhan, Hai-Xia Lu, Xi Chen
BACKGROUND: Root caries are prevalent issues that affect dental health, particularly among elderly individuals with exposed root surfaces. Fluoride therapy has shown effectiveness in preventing root caries, but limited studies have addressed its cost-effectiveness in elderly persons population. This study aimed to evaluate the cost-effectiveness of a fluoride treatment program for preventing root caries in elderly persons within the context of Chinese public healthcare. METHODS: A Markov simulation model was adopted for the cost-effectiveness analysis in a hypothetical scenario from a healthcare system perspective...
April 22, 2024: BMC Oral Health
https://read.qxmd.com/read/38649198/efforts-to-improve-the-billing-accuracy-of-robotic-assisted-thoracic-surgery-through-education-updated-procedure-cards-and-electronic-medical-record-system-changes
#22
JOURNAL ARTICLE
Kevin A Wu, Kenneth Boccaccio, Danielle Buckles, Matthew G Hartwig, Jacob A Klapper
Precise medical billing is essential for decreasing hospital liability, upholding environmental stewardship and ensuring fair costs for patients. We instituted a multifaceted approach to improve the billing accuracy of our robotic-assisted thoracic surgery programme by including an educational component, updating procedure cards and removing the auto-populating function of our electronic medical record. Overall, we saw significant improvements in both the number of inaccurate billing cases and, specifically, the number of cases that overcharged patients...
April 22, 2024: BMJ Open Quality
https://read.qxmd.com/read/38648846/health-care-lobbying-and-oncology
#23
JOURNAL ARTICLE
Nirmal Choradia, Aaron Mitchell, Ryan Nipp
BACKGROUND: The health care industry spends more on lobbying than any other industry, with more than $700 million spent in 2022. However, health care lobbying related to cancer has not been characterized. In this study, we sought to describe overall health sector lobbying spending and oncology-related lobbying spending across patient and clinician organizations. METHODS: We obtained lobbying data from OpenSecrets.org and the Federal Election Commission. Overall health sector lobbying spending was categorized by OpenSecrets into 4 groups: pharmaceuticals/health products, health services/health maintenance organizations (HMOs), hospitals/nursing homes, and health professionals...
April 19, 2024: Journal of the National Comprehensive Cancer Network: JNCCN
https://read.qxmd.com/read/38648666/best-practice-for-therapeutic-drug-monitoring-of-infliximab-position-statement-from-the-international-association-of-therapeutic-drug-monitoring-and-clinical-toxicology
#24
JOURNAL ARTICLE
Dahham Alsoud, Dirk Jan A R Moes, Zhigang Wang, Rani Soenen, Zohra Layegh, Murray Barclay, Tomoyuki Mizuno, Iris K Minichmayr, Ron J Keizer, Sebastian G Wicha, Gertjan Wolbink, Jo Lambert, Séverine Vermeire, Annick de Vries, Konstantinos Papamichael, Núria Padullés-Zamora, Erwin Dreesen
BACKGROUND: Infliximab, an anti-tumor necrosis factor monoclonal antibody, has revolutionized the pharmacological management of immune-mediated inflammatory diseases (IMIDs). This position statement critically reviews and examines existing data on therapeutic drug monitoring (TDM) of infliximab in patients with IMIDs. It provides a practical guide on implementing TDM in current clinical practices and outlines priority areas for future research. METHODS: The endorsing TDM of Biologics and Pharmacometrics Committees of the International Association of TDM and Clinical Toxicology collaborated to create this position statement...
April 17, 2024: Therapeutic Drug Monitoring
https://read.qxmd.com/read/38648178/analysis-of-participant-stigma-and-associated-costs-of-a-peer-led-social-media-hiv-intervention
#25
JOURNAL ARTICLE
Navkiranjit Gill, Jim E Banta, Leonard Gashugi, Sean D Young
HIV-related stigma is a primary barrier to seeking HIV care. Online social media interventions utilizing peer-led approaches provide an opportunity to revolutionize HIV health behavior change. Secondary analysis of the UCLA HOPE Study (6 waves) was done to examine the effectiveness of an online peer-led intervention in reducing HIV-related internalized stigma (IS), association between IS and sexual risk behaviors (SRB), and associated costs for changing the likelihood of HIV testing. Among 897 participants, an inverse relationship between IS (Discomfort with people with HIV, Stereotypes, Moral Judgment) and SRB (Number of Sexual Partners, Sexual Encounters) factors was identified over time ( p < ...
April 2024: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://read.qxmd.com/read/38648092/stimulating-preconception-care-uptake-by-women-with-a-vulnerable-health-status-through-a-mobile-health-app-pregnant-faster-pilot-feasibility-study
#26
JOURNAL ARTICLE
Sharissa M Smith, Babette Bais, Hafez Ismaili M'hamdi, Maartje Hn Schermer, Régine Pm Steegers-Theunissen
BACKGROUND: A low socioeconomic status is associated with a vulnerable health status (VHS) through the accumulation of health-related risk factors, such as poor lifestyle behaviors (eg, inadequate nutrition, chronic stress, and impaired health literacy). For pregnant women, a VHS translates into a high incidence of adverse pregnancy outcomes and therefore pregnancy-related inequity. We hypothesize that stimulating adequate pregnancy preparation, targeting lifestyle behaviors and preconception care (PCC) uptake, can reduce these inequities and improve the pregnancy outcomes of women with a VHS...
April 22, 2024: JMIR Human Factors
https://read.qxmd.com/read/38648083/tailr-nursing-sensitive-events-and-their-association-with-individual-nurse-staffing-levels-project-protocol-for-an-international-longitudinal-multicenter-study
#27
JOURNAL ARTICLE
Stefanie Bachnick, Maria Unbeck, Maryam Ahmadi Shad, Katja Falta, Nicole Grossmann, Daniela Holle, Jana Bartakova, Sarah N Musy, Sarah Hellberg, Pernilla Dillner, Fatemeh Atoof, Mohammadhossein Khorasanizadeh, Paula Kelly-Pettersson, Michael Simon
BACKGROUND: Nursing-sensitive events (NSEs) are common, accounting for up to 77% of adverse events in hospitalized patients (eg, fall-related harm, pressure ulcers, and health care-associated infections). NSEs lead to adverse patient outcomes and impose an economic burden on hospitals due to increased medical costs through a prolonged hospital stay and additional medical procedures. To reduce NSEs and ensure high-quality nursing care, appropriate nurse staffing levels are needed. Although the link between nurse staffing and NSEs has been described in many studies, appropriate nurse staffing levels are lacking...
April 22, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38647974/economic-assessment-of-abemaciclib-for-the-adjuvant-treatment-of-luminal-her2-breast-cancer-from-the-perspective-of-the-spanish-health-system
#28
JOURNAL ARTICLE
Silvia Fenix-Caballero, Adrián Sanchez-Vegas, Emilio Jesús Alegre Del-Rey, David Epstein, Leticia Garcia-Mochon, Antonio Olry de Labry Lima
INTRODUCTION: Abemaciclib is an oral inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). Data from the clinical trial monarchE (2023) showed improved survival from invasive disease. The aim of the present article was to conduct an economic assessment of adjuvant treatment with abemaciclib in women with luminal, HER2- and node-positive breast cancer. METHODS: A Markov model was constructed with four mutually exclusive health states (disease-free, local recurrence, distal recurrence and death)...
April 22, 2024: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://read.qxmd.com/read/38647493/potential-parental-determinants-of-the-pace-of-evidence-based-practice-change-in-children-s-mental-health-care
#29
JOURNAL ARTICLE
Matthew M Davis, Marie E Heffernan, Lucy A Bilaver, Lauren S Wakschlag, Neil Jordan, Justin D Smith
BACKGROUND: Strength of evidence is key to advancing children's mental health care but may be inadequate for driving practice change. The Designing for Accelerated Translation (DART) framework proposes a multifaceted approach: pace of implementation as a function of evidence of effectiveness, demand for the intervention, sum of risks, and costs. To inform empirical applications of DART, we solicited caregiver preferences on key elements. METHOD: In March-April 2022, we fielded a population-representative online survey in Illinois households (caregivers N = 1,326) with ≥1 child <8 years old...
March 2024: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://read.qxmd.com/read/38647489/addressing-mental-health-earlier-in-pediatric-primary-care-introduction-to-the-special-section
#30
JOURNAL ARTICLE
Ashley M Butler, Sara M George
Leading national health organizations have declared pediatric mental health an urgent public health issue. Pediatric primary care is an ideal setting to improve mental health in young children; however, various existing barriers limit the effective identification of social-emotional risk among toddlers. This special section of Families, Systems, & Health includes four articles that identify multilevel barriers and facilitators to population-level early childhood mental health screening, identification, and referral and describe implementation strategies that may be used to improve pediatric mental health...
March 2024: Families, Systems & Health: the Journal of Collaborative Family Healthcare
https://read.qxmd.com/read/38646039/unit-cost-and-hope-increased-nhs-resilience-through-tech-enabled-transformation
#31
JOURNAL ARTICLE
Timothy G Ferris
No abstract text is available yet for this article.
March 2024: Future Healthcare Journal
https://read.qxmd.com/read/38645669/costs-of-air-pollution-in-california-s-san-joaquin-valley-a-societal-perspective-of-the-burden-of-asthma-on-emergency-departments-and-inpatient-care
#32
JOURNAL ARTICLE
Gilda Zarate-Gonzalez, Paul Brown, Ricardo Cisneros
INTRODUCTION: The San Joaquin Valley (SJV) is often recognized as one of the most polluted regions in the US. Periods of pollution exposure are associated with increased health burden related to respiratory inflammation and undermined lung function, which aggravates respiratory diseases such as asthma and leads to symptoms such as coughing, wheezing, or difficulty breathing. Asthma costs US$ 82 billion annually in healthcare costs, missed work and school in the US. METHODS: Employing a societal perspective, a cost of illness design was combined with environmental epidemiological methods to analyze the economic impact of O3 , NO2 , and PM2...
2024: Journal of Asthma and Allergy
https://read.qxmd.com/read/38645447/toward-the-elimination-of-hepatitis-b-networking-to-promote-the-prevention-of-vertical-transmission-of-hepatitis-b-virus-through-population-based-interventions-and-multidisciplinary-groups-in-africa
#33
JOURNAL ARTICLE
Judith Ndongo Embola Torimiro, Kerina Duri, Nadège M Goumkwa, Solange M Atah, Juliette-Laure Ndzie Ondigui, Cindy Lobe, Marielle Bouyou, Bénédicte Ndeboko, Ali Mahamat Moussa, Camengo Police, Patrick Awoumou, Puinta Peyonga, Prisca V Djivida, Assah Felix, Godwin W Nchinda, Brigitte Wandji, Rachel K Simo, Sylvie Agnès Moudourou, Ana Gutierrez, Rosi Garcia, Isabelle Fernandez, Evelyn Mah, Sarah Rowland-Jones, Robinson Mbu
The WHO African Region had 81 million people with chronic hepatitis B in 2019, which remains a silent killer. Hepatitis B virus (HBV), hepatitis delta virus (HDV), and HIV can be transmitted from the mother to child. If the HBV infection is acquired at infancy, it may lead to chronic hepatitis B in 90% of the cases. WHO reports that 6.4 million children under 5 years live with chronic hepatitis B infection worldwide. The prevention of mother-to-child transmission (PMTCT) of HBV is therefore critical in the global elimination strategy of viral hepatitis as we take lessons from PMTCT of HIV programs in Africa...
2024: Frontiers in Public Health
https://read.qxmd.com/read/38645136/collateral-damage-of-nudt15-deficiency-in-cancer-provides-a-cancer-pharmacogenetic-therapeutic-window-with-thiopurines
#34
Jacob C Massey, Joseph Magagnoli, S Scott Sutton, Phillip J Buckhaults, Michael D Wyatt
Genome instability is a hallmark of cancer and are driven by mutations in oncogenes and tumor suppressor genes. Despite successes seen with select targeted therapeutics, this type of personalized medicine is only beneficial for a small subpopulation of cancer patients who have one of a few actionable genetic changes. Most tumors also contain hundreds of passenger mutations that offered no fitness advantage or disadvantage during tumor evolution. Mutations in known pharmacogenetic (PGx) loci for which germline variants encode variability in drug response can cause somatically acquired drug sensitivity...
April 11, 2024: bioRxiv
https://read.qxmd.com/read/38644929/monitoring-for-waste-evidence-from-medicare-audits
#35
JOURNAL ARTICLE
Maggie Shi
This paper examines the tradeoffs of monitoring for wasteful public spending. By penalizing unnecessary spending, monitoring improves the quality of public expenditure and incentivizes firms to invest in compliance technology. I study a large Medicare program that monitored for unnecessary healthcare spending and consider its effect on government savings, provider behavior, and patient health. Every dollar Medicare spent on monitoring generated $24-29 in government savings. The majority of savings stem from the deterrence of future care, rather than reclaimed payments from prior care...
May 2024: Quarterly Journal of Economics
https://read.qxmd.com/read/38644916/an-institutional-study-on-accuracy-of-freehand-cervical-c1-c2-screws-placement-by-knock-and-drill-technique-in-craniovertebral-anomalous-bony-anatomy-an-evaluation-of-more-than-600-screws-based-on-sgpgi-screw-accuracy-criteria
#36
JOURNAL ARTICLE
Sudhir Bisan Sasapardhi, Pawan Kumar Verma, Arun Kumar Srivastava, Kuntal Kanti Das, Ashutosh Kumar, Priyadarshi Dikshit, Ved Prakash Maurya, Kamlesh Singh Bhaisora, Anant Mehrotra, Awadhesh Kumar Jaiswal, Prabhaker Mishra, Sanjay Behari, Raj Kumar, Harshit Mishra, Kalyani Shahare
PURPOSE: To assess the accuracy of freehand cervical C1 C2 screws placement by knock and drill (K and D) technique in craniovertebral anomalous bony anatomy. MATERIALS AND METHODS: From January 2017 to December 2022, 682 consecutive C1 C2 screws in 215 patients with craniovertebral junction (CVJ) anomalies were enrolled. All patients underwent posterior fixation with K and D technique without any fluoroscopic guidance. The patient's demographic details, clinical details, radiological details, major intraoperative events, and postoperative complications were noted...
2024: Journal of Craniovertebral Junction and Spine
https://read.qxmd.com/read/38644576/toward-restorative-hospital-environment-nature-and-art-in-finnish-hospitals
#37
JOURNAL ARTICLE
Miia Heikkilä, Ira Verma, Suvi Nenonen
This study explores the integration of nature and art in recent hospital construction projects in Finland, focusing on public hospitals. Interviews with 15 stakeholders, including hospital executives, workers, designers, artists, and architects, reveal the value placed on nature and nature-themed art in hospital settings. The research question presented was: How nature and art are incorporated in Finnish hospitals in order to achieve a restorative hospital environment? Findings highlight themes that appeared in different hospitals: (1) the desired atmosphere, (2) nature and multisensory experiences, (3) social support, and (4) sense of connection and belonging...
April 21, 2024: HERD
https://read.qxmd.com/read/38644484/impact-of-the-covid-19-pandemic-on-utilization-and-cost-for-care-of-pediatric-and-young-adult-all
#38
JOURNAL ARTICLE
Alex Hoover, Dave Watson, Paige Reimche, Lynn Tanner, Laura Gilchrist, Mike Finch, Yoav H Messinger, Lucie M Turcotte
OBJECTIVE: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy and among the most common malignancies in young adults and requires a unique pattern of healthcare utilization including an acute/emergent presentation and an intensive initial 8 months of therapy followed by two years of outpatient treatment. The COVID-19 pandemic caused massive global disruptions in healthcare use and delivery. This report aims to examine the effects of the COVID-19 pandemic on the presentation, diagnosis and continued management of childhood and young adult ALL in regard to utilization and cost of care among commercially insured individuals in the United States...
April 22, 2024: BMC Research Notes
https://read.qxmd.com/read/38644160/associations-of-preoperative-anaemia-with-healthcare-resource-use%C3%A2-and-outcomes-after-colorectal-surgery-a-population-based-cohort-study
#39
JOURNAL ARTICLE
Lily J Park, Husein Moloo, Tim Ramsay, Kednapa Thavorn, Justin Presseau, Terry Zwiep, Guillaume Martel, P J Devereaux, Robert Talarico, Daniel I McIsaac
BACKGROUND: Preoperative anaemia is common in patient undergoing colorectal surgery. Understanding the population-level costs of preoperative anaemia will inform development and evaluation of anaemia management at health system levels. METHODS: This was a population-based cohort study using linked, routinely collected data, including residents from Ontario, Canada, aged ≥18 yr who underwent an elective colorectal resection between 2012 and 2022. Primary exposure was preoperative anaemia (haemoglobin <130 g L-1 in males; <120 g L-1 in females)...
April 20, 2024: British Journal of Anaesthesia
https://read.qxmd.com/read/38643955/leadership-s-perceptions-of-palliative-care-during-the-covid-19-pandemic-a-qualitative-study
#40
JOURNAL ARTICLE
Tamara Vesel, Audrey Covaleski, Veronica Burkarth, Emma Ernst, Linda Vesel
CONTEXT: Palliative care played a leading role in the COVID-19 pandemic. However, little is known regarding health system leadership's perceptions. BACKGROUND: This study aimed to explore the perceptions, understanding, and utilization of palliative care before compared to during the COVID-19 pandemic among health system leadership. METHODS: Semi-structured, in-depth interviews were conducted with leaders in a large healthcare system based in Massachusetts, United States...
April 19, 2024: Journal of Pain and Symptom Management
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