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Chen Zhang, Xia Xu
Diminished ovarian reserve (DOR) refers to the decreased production of mature ova in ovarium and decreased quality of oocyte, leading to deficiency of the female sex hormone and decreased fertility. DOR can also develop into premature ovarian failure, which affects female life quality and constitutes an important cause of female infertility. A fast lifestyle, environmental deterioration and accumulated understanding of this disease, have led to an increase in the incidence of DOR. Therefore, reasonable and effective treatment for DOR is particularly important to improve ovarian function and female life quality as well as reduce infertility...
April 2016: Experimental and Therapeutic Medicine
Atik Ismiyati, I Wayan Arsana Wiyasa, Dwi Yuni Nur Hidayati
A study was designed to investigate ameliorates effect of combined vitamins C and E able to against depot-medroxyprogesterone acetate- (DMPA-) induced ovarian oxidative stress in rat. Twenty-five female Wistar rats were divided into the following groups (n = 5 rats each): control (untreated) (C); depot-medroxyprogesterone acetate (DMPA); DMPA plus green vitamin C (at dose of 0.2 mg/gram; 0.4 mg/gram; 0.8 mg/gram) and vitamin E (0.04 IU/gram). The treatment with combined vitamins C and E was performed for four weeks...
2016: Journal of Toxicology
M Felsinger, L Minář, V Weinberger, R Hudeček
OBJECTIVE: Analysis of radical fertility preserving surgery, oncogynaecological treatment including their pregnancy effort. DESIGN: Prospective study. SETTING: Department of Obstetrics and Gynaecology, Masaryk University and Faculty Hospital Brno. METHODS: The group of 13 patients in age fifteen to thirty-six, who underwent radical fertility preserving surgery of oncogynecological tumors (cervix, ovarium), 9 patients with ovarian cancer and 4 patients with carcinoma of cervix...
October 2015: Ceská Gynekologie
Blanka Vavrinkova, Tomas Binder
Leyden-Möbius muscular dystrophy is an autosomal recessive hereditary disease of unknown aetiology; it is a congenital disorder of protein metabolism primarily affecting proximal muscle groups leading to progressive muscular dystrophy. It later spreads to the muscles of the pelvic floor and lower extremities. The estimated incidence is 1:200,000. This paper describe a case of pregnancy and delivery in woman with progressive Leyden-Moebius muscular dystrophy. Cesarean section was performed due to progression of the underlying disease...
2015: Neuro Endocrinology Letters
Irfan Eser, Hamza Karabag, Samil Gunay, Ahmet Seker, Muazzez Cevik, Zafer Hasan Ali Sak, Funda Yalcin, Mehmet Salih Aydin
INTRODUCTION: Hydatid cyst is a parasitic disease caused by Echinococcus granulosus whose people is the intermediate host. Although this parasite can settle in any part of the human body, it is frequently seen in liver and lungs. The rate of unusual located hydatid cyst outside of liver and lungs is 13,9%. In this study, we aimed presenting unusual located hydatic cysts regarding 51 patients. MATERIAL AND METHOD: In this retrospective study, the files of the patients operated in our department between 2005 and 2012 with the diagnosis of hydatid cyst, characterized be an additional location besides liver and lung involvement and located outside of liver and lung were controlled...
January 2014: Annali Italiani di Chirurgia
Jessica A Matts, Yuliya Sytnikova, Gung-Wei Chirn, Gabor L Igloi, Nelson C Lau
Increasingly, the discovery and characterization of small regulatory RNAs from a variety of organisms have all required deep-sequencing methodologies. However, the crux to successful deep-sequencing analysis depends upon optimal construction of a cDNA library compatible for the high-throughput sequencing platform. Challenges to small RNA library constructions arise when dealing with minute tissue samples because certain structural RNA fragments can dominate and mask the desired characterization of regulatory small RNAs like microRNAs (miRNAs), endogenous small interfering RNAs (endo-siRNAs), and Piwi-interacting RNAs (piRNAs)...
2014: Methods in Molecular Biology
Mustafa Nazıroğlu, Murat Yüksel, Seyit Ali Köse, Mehmet Okan Özkaya
Environmental exposure to electromagnetic radiation (EMR) has been increasing with the increasing demand for communication devices. The aim of the study was to discuss the mechanisms and risk factors of EMR changes on reproductive functions and membrane oxidative biology in females and males. It was reported that even chronic exposure to EMR did not increase the risk of reproductive functions such as increased levels of neoantigens abort. However, the results of some studies indicate that EMR induced endometriosis and inflammation and decreased the number of follicles in the ovarium or uterus of rats...
December 2013: Journal of Membrane Biology
Seren Gülşen Gürgen, Deniz Erdoğan, Ciğdem Elmas, Gülnur Take Kaplanoğlu, Ciğdem Ozer
OBJECTIVE: The aim of the study was to evaluate the protective efficacy of ascorbic acid, α-tocopherol, and selenium by measuring the glutathione (GSH) levels and proliferating cell nuclear antigen (PCNA) and growth differentiation factor-9 (GDF-9) expression in the ovarian tissues of rats treated with cyclophosphamide (CP) therapy. METHODS: Female Wistar rats were divided into 5 groups of 6 rats each: (I) control, (II) only CP, (III) CP + ascorbic acid, (IV) CP + α-tocopherol, and (V) CP + selenium...
May 2013: Nutrition
Masayuki Ando, Yoshihisa Watayou, Hideaki Ganno, Takeshi Nagahama, Akira Fukuda, Katsunori Ami, Toshiaki Kurokawa, Hidetoshi Amagasa, Jun Takasaki, Masahiro Nakamura, Keiichi Fujiya, Kuniyoshi Arai, Shikofumi Tei, Youichi Okada
A 37-year-old female, who had undergone a low anterior resection for lower rectal cancer, had been received chemotherapy (FOLFOX4, FOLFIRI) for 2 years because of right ovarian metastasis occurred and removed 9 months after the first operation. One month after 2 years of continued chemotherapy, progressive metastases happened to occur successively (rt lunge, left ovarium, liver, para-aortic lymphonode, Virchow lymphonode and bone). Right upper lobe pnemonectomy was performed first, then, peritonectomy, total hysterectomy with left oophorectomy and a partial resection of the small bowel were done...
November 2011: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Johsuke Hara, Kouichi Nishi, Yoshio Tsunezuka, Hiroshi Kurumaya, Kazuyoshi Katayanagi, Masaki Fujimura
We report here a case of pulmonary benign metastasizing leiomyoma (BML) from the uterus. A 48-year-old woman was admitted to our hospital because of multiple pulmonary nodules on the chest radiograph 7 years after total hysterectomy with removal of the left ovarium for uterine leiomyoma. A specimen of the lesion obtained by a thoracoscopic lung biopsy was consistent with leiomyoma. Histological re-evaluation of the uterine myoma showed similar histology as compared with the lung tumor. Immunohistological staining for both estrogen and progesterone receptors on the lung tissue was positive...
September 2011: Nihon Kokyūki Gakkai Zasshi, the Journal of the Japanese Respiratory Society
Y Yonemura, Y Endo, T Yamaguchi, T Fujimura, T Obata, T Kawamura, N Nojima, I Miyazaki, T Sasaki
To clarify the mechanisms of the formation of peritoneal dissemination, a new animal model by the i.p. inoculation of highly metastatic gastric cancer cell line MKN-45-P was developed. Peritoneal dissemination with bloody ascites was found in 100% of nude mice, injected 1x10(7) MKN-45-P cells in suspension into the peritoneal cavity. By a highly sensitive method for specific detection of metastasized human tumor cells in nude mice using polymerase chain reaction, a human beta-globin-related sequence in the DNA from various parts of the peritoneum was specifically amplified and detected by gel electrophoresis and by a specific oligonucleotide probe...
April 1996: International Journal of Oncology
Keita Okubo, Shinichi Yoshioka, Kei Asukai, Tomoki Hata, Misuzu Nakanishi, Takayo Maekawa, Naoki Hama, Masaki Kashiwazaki, Masaaki Taniguchi, Masaki Tsujie, Muneharu Konishi, Kouji Yano, Takayoshi Fujimoto
This is an account of a case of primary adenocarcinoma of the small intestine with peritoneal dissemination successfully treated with chemotherapy. A 64-year-old woman was admitted with a complaint of severe abdominal distension. Abdominal computerized tomography revealed a bowel obstruction with tumor and the remarkable small bowel dilation of oral side of tumor. The tumor was found at surgery to be at the ileum 15 cm proximal from the ileocecal region. Peritoneal dissemination was recognized around the ileocecal region, so ileum partial resection was performed for the primary cancer lesion and dissemination region...
November 2010: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Azusa Yamamoto, Keiichiro Ishibashi, Yusuke Tajima, Satoshi Hatano, Toru Ishiguro, Tomonori Osawa, Norimichi Okada, Kensuke Kumamoto, Masaru Yokoyama, Norihiro Haga, Hideyuki Ishida
We herein report an extremely rare operative case of an isolated extraperitoneal metastasis of colon cancer. A female patient had undergone a sigmoidectomy for ileus due to sigmoid colon cancer when she was 40 years old. Peritoneal metastasis, 5 mm in diameter, was on the sigmoid colon mesentery and she was histologically diagnosed as Stage IV. She received fluorouracil-based adjuvant chemotherapy for 24 months. Serum CEA increased gradually from 36 months after the operation, and CT scan demonstrated bilateral ovarium tumors...
November 2010: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Masatsugu Ishii, Keiichiro Ishibashi, Jun Sobajima, Tomonori Ohsawa, Norimichi Okada, Kensuke Kumamoto, Norihiro Haga, Masaru Yokoyama, Hideyuki Ishida
Pseudo-Meigs' syndrome caused by ovarian metastasis from colorectal cancer is extremely rare. The clinical symptoms of pleural effusion and ascites that are characteristics of pseudo-Meigs' syndrome are quite similar to those of terminal-stage colon cancer. Therefore, recognizing the clinical characteristics of pseudo-Meigs' syndrome is important. We investigated the prognosis and clinicopathological factors including age, location of the primary cancer, histology, wall depth, curative degree, synchronous/metachronous, unilateral/bilateral, lymph node metastasis, peritoneal dissemination, serum CEA level, venous invasion, and lymphatic invasion, in 5 cases of pseudo-Meigs' syndrome (PM group) and compared these findings with those of 10 cases with ovarian metastasis from colorectal cancer (control group) without pseudo-Meigs' syndrome...
November 2010: Gan to Kagaku Ryoho. Cancer & Chemotherapy
T M Greenhow
No abstract text is available yet for this article.
1844: Medico-chirurgical Transactions
J Bostock
No abstract text is available yet for this article.
1819: Medico-chirurgical Transactions
E Phillips
No abstract text is available yet for this article.
1818: Medico-chirurgical Transactions
S Merriman
No abstract text is available yet for this article.
1812: Medico-chirurgical Transactions
György Horvath, José Chilo, Thomas Lindblad
UNLABELLED: Many cancers are detected at a late stage resulting in high mortality rates. Thus, it is essential to develop inexpensive and simple methods for early diagnosis. Detection of different malignancies using canine scent, as well as other technical methods, has been reported in peer-reviewed journals, indicating that this may represent a new diagnostic tool for malignancies. AIM: This study aims to test the detection of different volatile organic compound signals emitted by ovarian carcinoma and normal tissues...
June 2010: Future Oncology
N D Koç, F E Kayhan, C Sesal, M N Muşlu
In this study, histological effects and malondialdehyde (MDA) levels were investigated by endosulfan and malathion in adult female rat ovaries. An increase of MDA level in rat ovarium tissues due to endosulfan and malathion may be an indicator of the free radicals occurred during the metabolism and their lipid peroxidative inducing damage. In this study in accordance with the biochemical findings, the study demonstrated that there are pronounced structural defects in histological examinations of ovarian tissues in rats which were administered endosulfan and malathion...
March 15, 2009: Pakistan Journal of Biological Sciences: PJBS
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