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https://www.readbyqxmd.com/read/29755826/pharmacovigilance-via-baseline-regularization-with-large-scale-longitudinal-observational-data
#1
Zhaobin Kuang, Peggy Peissig, Vítor Santos Costa, Richard Maclin, David Page
Several prominent public health hazards [29] that occurred at the beginning of this century due to adverse drug events (ADEs) have raised international awareness of governments and industries about pharmacovigilance (PhV) [6,7], the science and activities to monitor and prevent adverse events caused by pharmaceutical products after they are introduced to the market. A major data source for PhV is large-scale longitudinal observational databases (LODs) [6] such as electronic health records (EHRs) and medical insurance claim databases...
August 2017: KDD: Proceedings
https://www.readbyqxmd.com/read/29693423/landing-kinematics-in-elite-male-youth-soccer-players-of-different-chronologic-age-and-stage-of-maturation
#2
Paul J Read, Jon L Oliver, Mark B A De Ste Croix, Gregory D Myer, Rhodri S Lloyd
CONTEXT:   Despite the high frequency of knee injuries in athletes, few researchers have studied the effects of chronologic age and stage of maturation on knee-joint kinematics in male youth soccer players. OBJECTIVE:   To use a coach-friendly screening tool to examine knee-valgus scores for players of different ages and at different stages of maturation. DESIGN:   Cross-sectional study. SETTING:   Academy soccer clubs...
April 25, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29669435/optimal-design-for-longitudinal-studies-to-estimate-pubertal-height-growth-in-individuals
#3
Tim James Cole
BACKGROUND: The SITAR model expresses individual pubertal height growth in terms of mean size, peak height velocity (PHV) and age at PHV. AIM: To use SITAR to identify the optimal time interval between measurements to summarise individual pubertal height growth. SUBJECTS AND METHODS: Heights in 3172 boys aged 9-19 years from Christ's Hospital School measured on 128 679 occasions (a median of 42 heights per boy) were analysed using the SITAR (SuperImposition by Translation And Rotation) mixed effects growth curve model, which estimates a mean curve and three subject-specific random effects...
April 18, 2018: Annals of Human Biology
https://www.readbyqxmd.com/read/29668045/when-does-the-influence-of-maturation-on-anthropometric-and-physical-fitness-characteristics-increase-and-subside
#4
Christopher Towlson, Stephen Cobley, Guy Parkin, Ric Lovell
The relationships between maturation and anthropometric and physical performance characteristics are dynamic and often asynchronous; confounding the capability to accurately evaluate performance during adolescence. This study aimed to (i) examine the influence of chronological age (CA) and somatic maturation (YPHV) upon anthropometric and physical performance parameters, and (ii) identify the transition/change time-points in these relationships using segmental regression. N=969 soccer players (8-18 years of age) completed anthropometric and physical test assessments, including a counter-movement jump (CMJ), agility T-test, 10 and 20m sprints, and multi-stage fitness test (MSFT)...
April 18, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29611771/the-effects-of-maturation-on-jumping-ability-and-sprint-adaptations-to-plyometric-training-in-youth-soccer-players
#5
Abbas Asadi, Rodrigo Ramirez-Campillo, Hamid Arazi, Eduardo Sáez de Villarreal
The aim of this study was to investigate the effects of maturation on power and sprint performance adaptations following 6 weeks of plyometric training in youth soccer players during pre-season. Sixty male soccer players were categorized into 3 maturity groups (Pre, Mid and Post peak height velocity [PHV]) and then randomly assigned to plyometric group and control group. Vertical jump, standing long jump, and 20-m sprint (with and without ball) tests were collected before- and after-intervention. After the intervention, the Pre, Mid and Post-PHV groups showed significant (P ≤ 0...
April 3, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29599859/functional-movements-in-japanese-mini-basketball-players
#6
Kenji Kuzuhara, Masashi Shibata, Junta Iguchi, Ryo Uchida
Functional movement screen (FMS) has been used to establish normative data and determine potential injury risk for young adults and athletes, but there are few data in elementary school-age children. The purpose of this study was to establish fundamental values for the FMS in elementary school-age mini-basketball players. Secondary purposes were to examine relationships between functional movement patterns and age, peak height velocity (PHV), and body mass index (BMI), and to compare functional movement patterns between boys and girls and between individuals with and without a history of injury...
March 2018: Journal of Human Kinetics
https://www.readbyqxmd.com/read/29580223/association-between-braced-curve-behavior-by-pubertal-growth-peak-and-bracing-effectiveness-in-female-idiopathic-scoliosis-a-longitudinal-cohort-study
#7
Sai-Hu Mao, Xu Sun, Ben-Long Shi, Yong Qiu, Bang-Ping Qian, Jack C Y Cheng
BACKGROUND: Pre-pubertal idiopathic scoliosis (IS) is associated with high risk of bracing ineffectiveness. Integrated multidimensional maturity assessments are useful but complex to predict the high-risk occurrence of curve progression. This study is designed to provide a simple screening method for brace effectiveness by determining whether or not the braced curve behavior at growth spurt, being defined as variations in Cobb angle velocity (AV) at peak height velocity (PHV), can be a new factor predictive of brace outcome prescribed before PHV...
March 27, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29547490/within-and-between-session-reliability-of-the-isometric-mid-thigh-pull-in-young-female-athletes
#8
Sylvia Moeskops, Jon L Oliver, Paul J Read, John B Cronin, Gregory D Myer, G Gregory Haff, Rhodri S Lloyd
To investigate the within- and between-session reliability of the isometric mid-thigh pull (IMTP) in pre- and post-peak height velocity (PHV) female athletes. Nineteen pre- and nineteen post-PHV athletes performed bilateral IMTPs using a custom-designed isometric testing system. Participants attended three separate testing-sessions, and performed three trials within each session. Peak force, relative peak force, force at 30, 50, 90, 100, 150, 200, and 250 milliseconds, rate of force development (RFD) within time-specific bands, time to peak force (TPF), and time to peak rate of force development (TPRFD) were obtained for analysis...
March 15, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29456759/ossification-of-the-phalanges-of-the-foot-and-its-relationship-to-peak-height-velocity-and-the-calcaneal-system
#9
M R Garcia, A D Nicholson, A M Nduaguba, J O Sanders, R W Liu, D R Cooperman
Purpose: There are multiple skeletal maturity grading systems, but none of them utilizes the phalanges of the foot. To minimize radiation, it would be ideal if one could assess the skeletal maturity of a foot based on bones seen on routine foot radiographs, if guided growth is being considered as a treatment option. We developed a system that correlates changes of the appearance of the foot phalanges to peak height velocity (PHV) and the recently described calcaneal apophyseal ossification grading system...
February 1, 2018: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29456758/binary-and-analogue-markers-of-skeletal-maturity-clinical-utility-of-the-thenar-and-plantar-sesamoids
#10
A D Nicholson, J O Sanders, R W Liu, D R Cooperman
Purpose: We investigate the thenar and plantar sesamoids as markers of skeletal maturity, and grade appearance using two scales, a binary system (absent or present), and an analogue system that relies upon judging regular changes in morphological appearance. Methods: We studied 94 healthy children (49 female and 45 male patients) between ages three and 18 years who had approximately 700 serially acquired sets of radiographs and physical examinations. The children had at least annual radiographs taken of the left hand and left foot...
February 1, 2018: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/29401199/effect-of-a-16-week-combined-strength-and-plyometric-training-program-followed-by-a-detraining-period-on-athletic-performance-in-pubertal-volleyball-players
#11
Abed Fathi, Raouf Hammami, Jason Moran, Rihab Borji, Sonia Sahli, Haithem Rebai
The purpose of this study was to determine the effects of 16 weeks of combined strength and plyometric training or plyometric training alone, and how a detraining program can modify adaptations in response to the training stimulus. Sixty male volleyball players (circa PHV:-1 to +1 years from PHV) were assigned to a Combined Training group (CTG) (n=20), a Plyometric Training group (PTG) (n=20) or a control group (CG) (n=20). The experimental groups (CTG and PTG) participated in training twice weekly for 16 weeks...
February 1, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29377329/efficient-production-and-characterization-of-homopolymeric-poly-3-hydroxyvalerate-produced-by-bacillus-strain-pjc48
#12
Jin-Jin Gu, Ying Zhou, Yan-Bin Tong, Jian-Jiang Lu, Bang-Ce Ye
Aliphatic polyester, poly(3-hydroxyvalerate) (PHV), is commonly produced as a granular component in bacterial cells of various species. Based on 16S rDNA gene sequence analysis, strain PJC48 was identified as a Bacillus species. The current study is aimed to screen for a high-yield strain that can produce PHV efficiently and to increase PHV product yield by optimizing the fermentative process. We identified a high-producer strain based on Nile red staining. Characterization of the PHV produced by PJC48 by nuclear magnetic resonance spectroscopy revealed that it consisted of (R)-3-hydroxyvalerate monomers...
January 29, 2018: Biotechnology and Applied Biochemistry
https://www.readbyqxmd.com/read/29369950/importance-of-speed-and-power-in-elite-youth-soccer-depends-on-maturation-status
#13
Conall F Murtagh, Thomas E Brownlee, Andrew OʼBoyle, Ryland Morgans, Barry Drust, Robert M Erskine
Murtagh, CF, Brownlee, TE, O'Boyle, A, Morgans, R, Drust, B, and Erskine, RM. Importance of speed and power in elite youth soccer depends on maturation status. J Strength Cond Res 32(2): 297-303, 2018-Maturation status is a confounding factor when identifying talent in elite youth soccer players (ESP). By comparing performance of ESP and control participants (CON) matched for maturation status, the aims of our study were to establish the importance of acceleration, sprint, horizontal-forward jump, and vertical jump capabilities for determining elite soccer playing status at different stages of maturation...
February 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29327955/co-occurrence-of-mycoplasma-species-and-pigeon-herpesvirus-1-infection-in-racing-pigeons-columba-livia
#14
Tom Hellebuyck, Stephan Göbel, Frank Pasmans, Connie Adriaensen, An Martel
Oropharyngeal swab samples were collected from 438 live racing pigeons ( Columba livia), with and without signs of respiratory disease, that were housed in 220 lofts in 3 provinces in the western part of the Netherlands. Polymerase chain reaction (PCR) was used to identify Mycoplasma species and pigeon herpesvirus-1 (PHV-1) from the samples. In 8.6% of the pigeon lofts tested, signs of respiratory disease were present in pigeons at sampling, and in 30.9% of the sampled pigeon lofts, respiratory signs were observed in pigeons during the 6-month period immediately before sampling...
December 2017: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/29276855/assessing-differences-in-cardiorespiratory-fitness-with-respect-to-maturity-status-in-highly-trained-youth-soccer-players
#15
Greg Doncaster, John Iga, Viswanath Unnithan
PURPOSE: The purpose of the study was to examine differences in measures of cardiorespiratory fitness and determinants of running economy with respect to maturity status in a group of highly trained youth soccer players. METHODS: A total of 21 highly trained youth soccer players participated in this study. On separate visits, players' peak oxygen uptake (VO2peak ), running economy at 3 different speeds [8 km·h-1 , 80% gaseous exchange threshold (GET), and 95% GET], and pulmonary oxygen uptake (VO2 ) kinetics were determined...
December 23, 2017: Pediatric Exercise Science
https://www.readbyqxmd.com/read/29250819/an-exploration-of-factors-associated-with-older-persons-perceptions-of-the-benefits-of-and-satisfaction-with-a-preventive-home-visit-service
#16
Mette Tøien, Ida Torunn Bjørk, Lisbeth Fagerström
BACKGROUND: Preventive home visits (PHVs) are healthcare services aimed at promoting the health of home-dwelling older people and to support their abilities to live independently. To enhance effectiveness, studies that explore older persons' experiences of PHVs are needed. OBJECTIVE: To assess older persons' perceived benefits and opinions of a PHV service and explore associations between perceived benefits from PHV and relevant sociodemographic/health-related factors...
December 18, 2017: Scandinavian Journal of Caring Sciences
https://www.readbyqxmd.com/read/29234912/advanced-ct-acquisition-protocol-with-a-third-generation-dual-source-ct-scanner-and-iterative-reconstruction-technique-for-comprehensive-prosthetic-heart-valve-assessment
#17
Marguerite E Faure, Laurens E Swart, Marcel L Dijkshoorn, Jos A Bekkers, Marcel van Straten, Koen Nieman, Paul M Parizel, Gabriel P Krestin, Ricardo P J Budde
OBJECTIVES: Multidetector CT (MDCT) is a valuable tool for functional prosthetic heart valve (PHV) assessment. However, radiation exposure remains a concern. We assessed a novel CT-acquisition protocol for comprehensive PHV evaluation at limited dose. METHODS: Patients with a PHV were scanned using a third-generation dual-source CT scanner (DSCT) and iterative reconstruction technique (IR). Three acquisitions were obtained: a non-enhanced scan; a contrast-enhanced, ECG-triggered, arterial CT angiography (CTA) scan with reconstructions at each 5 % of the R-R interval; and a delayed high-pitch CTA of the entire chest...
December 12, 2017: European Radiology
https://www.readbyqxmd.com/read/29214820/weight-management-behaviors-among-mexican-american-youth-cross-sectional-variation-by-timing-of-growth-and-maturation
#18
Jennifer L Gay, Eva V Monsma, Katie Darby Hein
PURPOSE: To assess the association between growth and maturation with weight management behaviors (WMBs) among Mexican American youth. DESIGN: A cross-sectional design was used to measure timing of growth and maturation as well as WMBs. SAMPLE: Students were recruited through physical education classes in south Texas schools. The sample included 623 participants (52.3% female; 49.8% with weight ≥85th percentile) in grades 4 through 12. Students in middle school were purposely oversampled to examine questions around timing of growth and maturation...
February 2018: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29196711/the-uniform-pattern-of-growth-and-skeletal-maturation-during-the-human-adolescent-growth-spurt
#19
James O Sanders, Xing Qiu, Xiang Lu, Dana L Duren, Raymond W Liu, Debbie Dang, Mariano E Menendez, Sarah D Hans, David R Weber, Daniel R Cooperman
Humans are one of the few species undergoing an adolescent growth spurt. Because children enter the spurt at different ages making age a poor maturity measure, longitudinal studies are necessary to identify the growth patterns and identify commonalities in adolescent growth. The standard maturity determinant, peak height velocity (PHV) timing, is difficult to estimate in individuals due to diurnal, postural, and measurement variation. Using prospective longitudinal populations of healthy children from two North American populations, we compared the timing of the adolescent growth spurt's peak height velocity to normalized heights and hand skeletal maturity radiographs...
December 1, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29194185/does-maturity-status-affect-the-relationship-between-anaerobic-speed-reserve-and-multiple-sprints-sets-performance-in-young-soccer-players
#20
Mohamed Amin Selmi, Badriya Al-Haddabi, Mohamed Haj Yahmed, Radhouane Haj Sassi
The purpose of this study is to examine the relationship between repeated-sprint sets (RSS) performance indices and anaerobic speed reserve (ASR) in young soccer players of different maturity status. One hundred and seventy nine young male soccer players (11.1 to 17.8 years) classified as pre- (n=50), circum- (n=60), or post- (n=69) peak height velocity (PHV) performed multi-stage shuttle run test (MRST) to measure maximal aerobic speed (MAS), 30-m sprint with 10-m splits to estimate maximal anaerobic speed (MAnS), and RSS test...
November 29, 2017: Journal of Strength and Conditioning Research
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