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Jay S Pepose, Joshua Burke, Mujtaba A Qazi
PURPOSE OF REVIEW: Presbyopia and cataract development are changes that ubiquitously affect the aging population. Considerable effort has been made in the development of intraocular lenses (IOLs) that allow correction of presbyopia postoperatively. The purpose of this review is to examine the benefits and barriers of accommodating IOLs, with a focus on emerging technologies. RECENT FINDINGS: True accommodation of an IOL involves a dynamic increase in dioptric power to affect a shift from distance to intermediate or near focus...
January 2017: Current Opinion in Ophthalmology
Mohammad Mehdi Sadoughi, Bahram Einollahi, Danial Roshandel, Mohammad Sarimohammadli, Sepehr Feizi
PURPOSE: To compare distant and near visual function after cataract surgery with implantation of Crystalens HD or Tek-Clear as accommodating intraocular lenses (IOLs), versus SA60AT as a standard IOL. METHODS: The study included 62 eyes of 58 patients divided into three groups using three different IOLs: Crystalens HD (Bausch and Lomb, NY, USA), Tek-Clear (Tekia, CA, USA) and SA60AT (Alcon, TX, USA) were implanted in 23, 14 and 25 eyes, respectively. Corrected distant visual acuity (CDVA), uncorrected and distance corrected near visual acuities (UCNVA and DCNVA), near point of accommodation (NPA), spectacle freedom and patient satisfaction were assessed six months postoperatively and compared between the three groups...
October 2015: Journal of Ophthalmic & Vision Research
David P Piñero, Vicente J Camps, MarIa L Ramón, Verónica Mateo, Rafael J Pérez-CambrodI
PURPOSE: To evaluate the predictability of the refractive correction achieved with a positional accommodating intraocular lenses (IOL) and to develop a potential optimization of it by minimizing the error associated with the keratometric estimation of the corneal power and by developing a predictive formula for the effective lens position (ELP). MATERIALS AND METHODS: Clinical data from 25 eyes of 14 patients (age range, 52-77 years) and undergoing cataract surgery with implantation of the accommodating IOL Crystalens HD (Bausch and Lomb) were retrospectively reviewed...
May 2015: Indian Journal of Ophthalmology
Marta Ługowska, Michał Starus, Aleksandra Synder, Wojciech Omulecki, Michał Wilczyński
INTRODUCTION: Intraocular lens implantation is an important part of cataract surgery, as it has a significant influence on the final result. Accommodative intraocular lenses (IOLs) are the latest solution for the lack of accommodation in pseudophakic eyes. PURPOSE: To evaluate the quality of life of patients who underwent cataract surgery with accommodating IOL implantation and to compare the data with results of patients after standard monofocal IOL implantation...
2014: Klinika Oczna
Srividhya Vilupuru, Ling Lin, Jay S Pepose
PURPOSE: To compare monocular and binocular mesopic contrast sensitivity and through focus following monocular implantation with KAMRA small-aperture inlay (AcuFocus, Irvine, California, USA) vs binocular implantation with an accommodating or multifocal intraocular lens (IOL) implant. DESIGN: Three-treatment randomized clinical trial of presbyopia-correcting IOLs with comparison to results from a previous nonrandomized multicenter clinical trial on the KAMRA corneal inlay...
July 2015: American Journal of Ophthalmology
Jay S Pepose, Jon Hayashida, John Hovanesian, James Davies, Phillips Kirk Labor, Jeffrey Whitman, Harvey Carter, Michael Colvard, Phillip J Buckhurst, Omid Khodai, David Mittleman, Gregg Feinerman
PURPOSE: To evaluate the safety and effectiveness of the Trulign toric intraocular lens (IOL) in adults with cataract. SETTING: Eight private practices in the United States and 1 in Canada. DESIGN: Prospective randomized single-masked multicenter study. METHODS: A toric IOL (1.25 D, 2.00 D, or 2.75 D, determined by a toric calculator) was implanted in eligible patients with age-related cataract requiring a 16.00 to 27...
February 2015: Journal of Cataract and Refractive Surgery
Jay S Pepose, Mujtaba A Qazi, Richard Chu, Jason Stahl
PURPOSE: To compare contrast sensitivity, visual acuity (VA), and halos in subjects bilaterally implanted with 1 of 3 FDA-approved presbyopia-correcting intraocular lenses. DESIGN: Prospective, randomized, partially masked, multicenter clinical trial. METHODS: Seventy-eight subjects were randomized sequentially for bilateral implantation with the Crystalens AO (Bausch & Lomb Surgical), AcrySof IQ ReSTOR +3.0 (Alcon Laboratories), or Tecnis Multifocal (Abbott Medical Optics) lenses...
September 2014: American Journal of Ophthalmology
Alexandra E Karavitaki, Ioannis G Pallikaris, Sophia I Panagopoulou, George A Kounis, George Kontadakis, George D Kymionis
PURPOSE: Our purpose was to evaluate the long-term visual outcomes after bilateral implantation of Crystalens(®) HD (Bausch and Lomb, Inc.) accommodative intraocular lenses. METHODS: In this study, 25 patients (50 eyes) who underwent cataract surgery and bilateral Crystalens HD accommodative intraocular lens implantation were included. The Crystalens HD lens was implanted in the bag in both eyes, without any intra- or postoperative complications. The visual parameters measured before and after surgery were: uncorrected distance visual acuity, corrected distance visual acuity (CDVA) (using the Early Diabetic Retinopathy Study [EDTRS] logMAR charts), uncorrected intermediate visual acuity, and uncorrected near visual acuity using a Birkhäuser reading chart, at a distance of 66 cm and 33 cm for intermediate and near vision, respectively, directly illuminated by a lamp of 60 watts...
2014: Clinical Ophthalmology
Hon Shing Ong, Jennifer R Evans, Bruce D S Allan
BACKGROUND: Following cataract surgery and intraocular lens (IOL) implantation, loss of accommodation or postoperative presbyopia occurs and remains a challenge. Standard monofocal IOLs correct only distance vision; patients require spectacles for near vision. Accommodative IOLs have been designed to overcome loss of accommodation after cataract surgery. OBJECTIVES: To define (a) the extent to which accommodative IOLs improve unaided near visual function, in comparison with monofocal IOLs; (b) the extent of compromise to unaided distance visual acuity; c) whether a higher rate of additional complications is associated the use of accommodative IOLs...
2014: Cochrane Database of Systematic Reviews
Pablo Pérez-Merino, Judith Birkenfeld, Carlos Dorronsoro, Sergio Ortiz, Sonia Durán, Ignacio Jiménez-Alfaro, Susana Marcos
PURPOSE: To evaluate the objective accommodative response, change of aberrations, and depth of focus in eyes implanted with the Crystalens accommodative intraocular lens (IOL) at different accommodative demands. DESIGN: Prospective, observational study. METHODS: Eleven cataract patients (22 eyes) who underwent implantation of a Crystalens accommodative IOL, and control groups of 9 normal subjects (17 eyes) and 17 pseudophakic patients (17 eyes) implanted with monofocal IOLs were evaluated...
May 2014: American Journal of Ophthalmology
Anish Dhital, David J Spalton, Kavita B Gala
PURPOSE: To compare visual acuity, intraocular lens (IOL) movement, and depth of focus with the Crystalens HD single-optic accommodating IOL and the Tecnis ZCB00 aspheric monofocal IOL. SETTING: St. Thomas' Hospital, London, United Kingdom. DESIGN: Prospective randomized controlled trial. METHODS: Patients with bilateral symptomatic cataract had bilateral sequential cataract surgery within 6 weeks with randomized implantation of the accommodating or monofocal IOL in both eyes...
December 2013: Journal of Cataract and Refractive Surgery
Efstathios T Detorakis, Alexandra Karavitaki, Nela Stojanovic, George Kontadakis, Ioannis G Pallikaris
This study employs optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM) imaging as well as optical aberrometry to examine correlations between the anterior chamber angle aperture and visual acuity for near vision as well as coma along the horizontal and vertical axes in eyes implanted with an accommodative intraocular lens (Crystalens). A retrospective comparative consecutive case series of 22 eyes of 11 patients (5 males) uneventfully implanted with a Crystalens. Eyes with signs of posterior capsular opacification were excluded...
August 2014: International Ophthalmology
Re Ang, Ga Martinez, Em Cruz, Aa Tiongson, Ag Dela Cruz
PURPOSE: To compare the visual acuity and quality of vision achieved with three widely-used intraocular lenses (IOLs) in subjects with bilateral cataracts. PATIENTS AND METHODS: This three-arm, parallel, prospective, partially masked, single-surgeon study randomized 78 subjects to receive bilateral Crystalens® Advanced Optics (AO) accommodating IOLs, AcrySof® IQ ReSTOR® +3.0 multifocal IOLs, or TECNIS® Multifocal IOLs. Examinations were assessed through days 120 to 180...
2013: Clinical Ophthalmology
Cari Pérez-Vives, Robert Montés-Micó, Norberto López-Gil, Teresa Ferrer-Blasco, Santiago García-Lázaro
PURPOSE: To compare visual and optical quality of the Crystalens HD intraocular lens (IOL) with that of a monofocal IOL. METHODS: The wavefront aberration patterns of the monocular Akreos Adapt AO IOL and the single-optic accommodating Crystalens HD IOL were measured in a model eye. The Crystalens IOL was measured in its nonaccommodative state and then, after flexing the haptic to produce 1.4 mm of movement, in its accommodative state. Using an adaptive optics system, subjects' aberrations were removed and replaced with those of pseudophakes viewing with either lens...
December 2013: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Susana Marcos, Sergio Ortiz, Pablo Pérez-Merino, Judith Birkenfeld, Sonia Durán, Ignacio Jiménez-Alfaro
OBJECTIVE: To quantify 3-dimensionally the anterior segment geometry, biometry, and lens position and alignment in patients before and after implantation of the Crystalens-AO (Bausch & Lomb, Rochester, NY) accommodating intraocular lens (A-IOL). DESIGN: Prospective, observational study. PARTICIPANTS: Ten patients (20 eyes) with cataract before and after implantation of the Crystalens-AO A-IOL. METHODS: Custom full anterior segment 3-dimensional (3-D) spectral optical coherence tomography (OCT) provided with quantification tools was used to image the cornea, iris, and natural lens preoperatively and intraocular lens postoperatively...
January 2014: Ophthalmology
Katherine V Zamora-Alejo, Sacha Pierre Moore, Douglas G A Parker, Katja Ullrich, Adrian Esterman, Michael Goggin
PURPOSE: Objective evaluation of accommodation with a bilateral accommodating intraocular lens (IOL) versus monofocal IOLs. METHODS: Patients received accommodating IOL (Crystalens HD; Bausch & Lomb, Rochester, NY) bilaterally after cataract surgery. These were compared to a matched group receiving monofocal IOLs. Preoperative and postoperative distance corrected distance, intermediate, and near vision were evaluated. Objective accommodation was measured with the WAM-5500 Binocular Autorefractor/Keratometer (Grand Seiko, Pty Ltd...
February 2013: Journal of Refractive Surgery
George H H Beiko
PURPOSE: To compare near vision and quality of vision after controlling for pseudoaccommodation in patients with single-optic accommodating intraocular lenses (IOLs) or monofocal IOLs targeted for mini-monovision. SETTING: Clinical practice. DESIGN: Prospective randomized controlled clinical trial. METHODS: Patients were randomized to bilateral implantation of the Crystalens HD silicone accommodating IOL, the Tetraflex acrylic accommodating IOL, or the Tecnis 1-piece monofocal (nonaccommodating) control IOL...
January 2013: Journal of Cataract and Refractive Surgery
Andrea Szigeti, Kinga Kránitz, Agnes I Takacs, Kata Miháltz, Michael C Knorz, Zoltán Z Nagy
PURPOSE: To evaluate the long-term visual outcome and intraocular (IOL) position parameters with a single-optic accommodating IOL after 5.5- or 6.0-mm femtosecond laser capsulotomy. METHODS: This prospective, randomized, pilot study comprised 17 eyes from 11 patients (7 men) with a mean age of 65.82±10.64 years (range: 51 to 79 years). All patients received a Crystalens AT-50AO (Bausch & Lomb) accommodating IOL after femtosecond laser refractive cataract surgery using either a 5...
September 2012: Journal of Refractive Surgery
Jorge L Alió, Ana B Plaza-Puche, Raúl Montalban, Paula Ortega
PURPOSE: To compare the visual and ocular optical performance in eyes with a single-optic or a dual-optic accommodating intraocular lens (IOL) with particular attention to near-vision outcomes. SETTING: Vissum Instituto Oftalmológico de Alicante, Miguel Hérnandez University, Alicante, Spain. DESIGN: Prospective consecutive nonrandomized interventional comparative clinical study. METHODS: Eyes with cataract were divided into 2 groups...
September 2012: Journal of Cataract and Refractive Surgery
Len Zheleznyak, Myoung Joon Kim, Scott MacRae, Geunyoung Yoon
PURPOSE: To measure the impact of corneal aberrations on the through-focus image quality of presbyopia-correcting intraocular lenses (IOLs) using an adaptive optics IOL metrology system. SETTING: Flaum Eye Institute, University of Rochester, Rochester, New York, USA. DESIGN: Experimental study. METHODS: An adaptive optics IOL metrology system comprising a model eye, wavefront sensor, deformable mirror, and an image-capturing device acquired through-focus images of a letter chart with 3...
October 2012: Journal of Cataract and Refractive Surgery
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