Cong Xi, Hua Zhao, Hai-Xiang Liu, Jia-Qi Xiang, Xue Lu, Tian-Jing Cai, Shuang Li, Ling Gao, Xue-Lei Tian, Ke-Hui Liu, Mei Tian, Qing-Jie Liu
INTRODUCTION: In the event of radiological accidents and cancer radiotherapies in clinic, the gastrointestinal (GI) system is vulnerable to ionizing radiation and shows GI injury. Accessible biomarkers may provide means to predict, evaluate, and treat GI tissue damage. The current study investigated radiation GI injury biomarkers in rat plasma. MATERIAL AND METHODS: High-coverage targeted lipidomics was employed to profile lipidome perturbations at 72 h after 0, 1, 2, 3, 5 and 8 Gy (60 Co γ-rays at 1 Gy/min) total-body irradiation in male rat jejunum...
March 22, 2022: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals