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frailty 32 items

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https://www.readbyqxmd.com/read/29788032/tracking-changes-in-frailty-throughout-later-life-results-from-a-17-year-longitudinal-study-in-the-netherlands
#1
Emiel O Hoogendijk, Kenneth Rockwood, Olga Theou, Joshua J Armstrong, Bregje D Onwuteaka-Philipsen, Dorly J H Deeg, Martijn Huisman
Background: to better understand the development of frailty with ageing requires longitudinal studies over an extended time period. Objective: to investigate changes in the degree of frailty during later life, and the extent to which changes are determined by socio-demographic characteristics. Methods: six measurement waves of 1,659 Dutch older adults aged 65 years and over in the Longitudinal Aging Study Amsterdam (LASA) yielded 5,211 observations over 17 years...
May 19, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29728064/validation-of-an-automatically-generated-screening-score-for-frailty-the-care-assessment-need-can-score
#2
Jorge G Ruiz, Shivani Priyadarshni, Zubair Rahaman, Kimberly Cabrera, Stuti Dang, Willy M Valencia, Michael J Mintzer
BACKGROUND: Frailty is a state of vulnerability to stressors that is prevalent in older adults and is associated with higher morbidity, mortality and healthcare utilization. Multiple instruments are used to measure frailty; most are time-consuming. The Care Assessment Need (CAN) score is automatically generated from electronic health record data using a statistical model. The methodology for calculation of the CAN score is consistent with the deficit accumulation model of frailty. At a 95 percentile, the CAN score is a predictor of hospitalization and mortality in Veteran populations...
May 4, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29567079/early-onset-physical-frailty-in-adults-with-diabesity-and-peripheral-neuropathy
#3
Lori J Tuttle, Daniel C Bittel, Adam J Bittel, David R Sinacore
OBJECTIVES: Diabesity (obesity and diabetes mellitus) has been identified as a potential contributor to early-onset frailty. Impairments contributing to early onset of physical frailty in this population are not well understood, and there is little evidence of the impact of peripheral neuropathy on frailty. The purpose of this study was to determine impairments that contribute to early-onset physical frailty in individuals with diabesity and peripheral neuropathy. METHODS: We studied 105 participants, 82 with diabesity and peripheral neuropathy (57 years of age, body mass index [BMI] 31 kg/m2 ); 13 with diabesity only (53 years of age, BMI 34 kg/m2 ) and 10 obese controls (67 years of age, BMI 32 kg/m2 )...
December 7, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29439853/frailty-predicts-incident-urinary-incontinence-among-hospitalized-older-adults-a-1-year-prospective-cohort-study
#4
Edward Chong, Mark Chan, Wee Shiong Lim, Yew Yoong Ding
OBJECTIVES: The relationship between frailty and urinary incontinence (UI) remains highly complex. There is limited data on the impact of frailty on new-onset UI among hospitalized older adults. Thus, we examined the ability of frailty to predict incident UI among them. DESIGN: Prospective cohort study. SETTING: Acute geriatric unit at a large teaching hospital. PARTICIPANTS: Older adults hospitalized for an acute medical illness...
May 2018: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29395372/a-high-whey-protein-vitamin-d-and-e-supplement-preserves-muscle-mass-strength-and-quality-of-life-in-sarcopenic-older-adults-a-double-blind-randomized-controlled-trial
#5
Yacong Bo, Changfeng Liu, Zhe Ji, Ruihong Yang, Qianqian An, Xueyuan Zhang, Jie You, Dandan Duan, Yafei Sun, Yiwei Zhu, Han Cui, Quanjun Lu
OBJECTIVE: Sarcopenia, an age-related decline of muscle mass, strength, and physical function, was associated with falls, frailty, and poor quality of life. The aim of the current study is to examine the effect of nutritional supplement containing whey protein, vitamin D and E on measures of sarcopenia. METHODS: A total of 60 sarcopenic older adult subjects participated in the current randomized, double-blind, placebo-controlled (iso-caloric control product) trial for 6 months...
January 9, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29181767/frailty-diabetes-and-the-convergence-of-chronic-disease-in-an-age-related-condition-a-population-based-nationwide-cross-sectional-analysis-of-the-mexican-nutrition-and-health-survey
#6
Roberto C Castrejón-Pérez, Carlos A Aguilar-Salinas, Luis M Gutiérrez-Robledo, Matteo Cesari, Mario U Pérez-Zepeda
AIMS: To describe the associations of frailty with diabetes mellitus and related conditions in older adults. METHODS: We conducted a cross-sectional analysis of a representative sample of older adults (n = 5379). We generated a 35-item frailty index (FI) and obtained information on diabetes and related conditions (peripheral neuropathy, lower limb amputation, diabetic coma, number of physician visits due to diabetes-related conditions, all-cause hospitalizations in the past year, years since diabetes diagnosis, and type of treatment)...
November 27, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29156480/-frailty-prevalence-in-the-resident-population-of-germany-70%C3%A2-%C3%A2-79-years-of-age-a-population-based-approach
#7
Judith Fuchs, Markus Busch, Christa Scheidt-Nave
In all countries life expectancy is rising, and many older persons spend a longer period in good health. Nevertheless, frailty is present in older people and can be considered as a risk factor for limitations. The "German Health Interview and Examination Survey for Adults" (DEGS1) 2008 - 2011 comprised interviews, examinations and tests. Data on 1110 community-dwelling people aged 70 to 79 years participating in DEGS1 with full records on frailty were analysed. Physical frailty was defined as exhaustion (SF-36 item), low grip strength, slowness (Timed Up-and-Go test > 15 seconds or unable to perform) and low physical activity (no sports or exertion)...
November 2017: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/29140924/the-association-between-pain-and-frailty-among-chinese-community-dwelling-older-adults-depression-as-a-mediator-and-its-interaction-with-pain
#8
Xiaoyu Tian, Cuili Wang, Xiaoxia Qiao, Na Liu, Lijuan Dong, Mary Butler, Huaxin Si, Yaru Jin
Pain and frailty are both prevalent and have severe health impacts among older adults. We conducted a cross-sectional observational study to examine the association between pain and frailty, and depression as a mediator and its interaction with pain on frailty among 1788 Chinese community-dwelling older adults. Physical frailty, pain intensity and depressive symptoms were assessed using the Frailty Phenotype, the revised Faces Pain Scale (FPS-R), and the 5-item Geriatric Depression Scale (GDS-5), respectively...
November 13, 2017: Pain
https://www.readbyqxmd.com/read/29135914/cross-cultural-adaptation-of-the-social-vulnerability-index-for-use-in-the-dutch-context
#9
Steven Bunt, Nardi Steverink, Melissa K Andrew, Cees P van der Schans, Hans Hobbelen
Being able to identify socially frail older adults is essential for designing interventions and policy and for the prediction of health outcomes, both on the level of individual older adults and of the population. The aim of the present study was to adapt the Social Vulnerability Index (SVI) to the Dutch language and culture for those purposes. A systematic cross-cultural adaptation of the initial Social Vulnerability Index was performed following five steps: initial translation, synthesis of translations, back translation, a Delphi procedure, and a test for face validity and feasibility...
November 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28866737/a-frailty-index-from-common-clinical-and-laboratory-tests-predicts-increased-risk-of-death-across-the-life-course
#10
Joanna M Blodgett, Olga Theou, Susan E Howlett, Kenneth Rockwood
A frailty index (FI) based entirely on common clinical and laboratory tests might offer scientific advantages in understanding ageing and pragmatic advantages in screening. Our main objective was to compare an FI based on common laboratory tests with an FI based on self-reported data; we additionally investigated if the combination of subclinical deficits with clinical ones increased the ability of the FI to predict mortality. In this secondary analysis of the 2003-2004 and 2005-2006 National Health and Nutrition Examination Survey data, 8888 individuals aged 20+ were evaluated...
September 2, 2017: GeroScience
https://www.readbyqxmd.com/read/28844849/frailty-and-skeletal-muscle-in-older-adults-with-cancer
#11
Grant R Williams, Allison M Deal, Hyman B Muss, Marc S Weinberg, Hanna K Sanoff, Emily J Guerard, Kirsten A Nyrop, Mackenzi Pergolotti, Shlomit Strulov Shachar
OBJECTIVE: Computerized tomography (CT) imaging is routine in oncologic care and can be used to measure muscle quantity and composition that may improve prognostic assessment of older patients. This study examines the association of single-slice CT-assessed muscle measurements with a frailty index in older adults with cancer. MATERIALS AND METHODS: Using the Carolina Senior Registry, we identified patients with CT imaging within 60days ± of geriatric assessment (GA)...
January 2018: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/28752589/frailty-and-potentially-inappropriate-medication-use-at-nursing-home-transition
#12
Laura C Maclagan, Colleen J Maxwell, Sima Gandhi, Jun Guan, Chaim M Bell, David B Hogan, Nick Daneman, Sudeep S Gill, Andrew M Morris, Lianne Jeffs, Michael A Campitelli, Dallas P Seitz, Susan E Bronskill
BACKGROUND/OBJECTIVES: To estimate the prevalence of potentially inappropriate medication (PIM) use among older adults with cognitive impairment or dementia prior to and following admission to nursing homes and in relation to frailty. DESIGN: Retrospective cohort study using health administrative databases. SETTING: Ontario, Canada. PARTICIPANTS: 41,351 individuals with cognitive impairment or dementia, aged 66+ years newly admitted to nursing home between 2011 and 2014...
October 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28734497/functional-not-chronologic-age-frailty-index-predicts-outcomes-in-advanced-ovarian-cancer
#13
Amanika Kumar, Carrie L Langstraat, Stephanie R DeJong, Michaela E McGree, Jamie N Bakkum-Gamez, Amy L Weaver, Nathan K LeBrasseur, William A Cliby
OBJECTIVES: To assess the impact of frailty as measured by a frailty deficit index (FI) on outcomes in advanced epithelial ovarian cancer (EOC) after primary debulking surgery (PDS). METHODS: Women with Stage IIIC/IV EOC who underwent PDS between 1/1/2003-12/31/2011 were included. Medical records were reviewed for patient characteristics and outcomes. The FI includes 30 items scored at 0, 0.5 or 1 and is calculated by summing across all the item scores and dividing by the total...
October 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28603896/dietary-pattern-associated-with-frailty-results-from-nutrition-and-health-survey-in-taiwan
#14
Yen-Li Lo, Yao-Te Hsieh, Li-Lin Hsu, Shao-Yuan Chuang, Hsing-Yi Chang, Chih-Cheng Hsu, Ching-Yu Chen, Wen-Harn Pan
OBJECTIVES: To investigate whether dietary patterns are associated with frailty phenotypes in an elderly Taiwanese population. DESIGN: Cross-sectional. SETTING: Nutrition and Health Survey in Taiwan (NAHSIT), 2014-2016. PARTICIPANTS: Noninstitutionalized Taiwanese nationals aged 65 years and older enrolled in the NAHSIT (N = 923). MEASUREMENTS: Dietary intake was assessed using a 79-item food-frequency questionnaire (FFQ)...
September 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28178934/the-prevalence-and-incidence-of-frailty-in-pre-diabetic-and-diabetic-community-dwelling-older-population-results-from-beijing-longitudinal-study-of-aging-ii-blsa-ii
#15
Jagadish Kumar Chhetri, Zheng Zheng, Xitong Xu, Cuihong Ma, Piu Chan
BACKGROUND: Various factors including cardio-metabolic disorders are found to be correlated with frailty. With the increase in age, older adults are likely to have elevated blood glucose level. In this study we intend to investigate the prevalence and incidence of frailty in the pre-diabetic and diabetic community dwelling elderly population and the associated risk factors. METHODS: At baseline total of 10,039 subjects with a mean age of 70.51 (±7.82) were included...
February 8, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/27896796/development-and-validation-of-a-frailty-index-in-the-longitudinal-aging-study-amsterdam
#16
Emiel O Hoogendijk, Olga Theou, Kenneth Rockwood, Bregje D Onwuteaka-Philipsen, Dorly J H Deeg, Martijn Huisman
BACKGROUND: Frailty is a state of increased vulnerability to adverse outcomes. The frailty index (FI), defined by the deficit accumulation approach, is a sensitive instrument to measure levels of frailty, and therefore important for longitudinal studies of aging. AIMS: To develop an FI in the Longitudinal Aging Study Amsterdam (LASA), and to examine the predictive validity of this FI for 19-year mortality. METHODS: LASA is an ongoing study among Dutch older adults, based on a nationally representative sample...
October 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27695646/the-impact-of-strong-for-life-on-the-physical-functioning-and-health-of-older-adults-receiving-home-and-community-based-services
#17
Margaret Danilovich, Daniel Corcos, Amy Eisenstein, David Marquez, Susan Hughes
BACKGROUND/OBJECTIVES: To test the effects of Strong for Life (SFL) on the physical performance and self-rated health of older adults receiving Home and Community-Based Services (HCBS). DESIGN: Randomized, two-group trial with pre-post measures. SETTING: In-home exercise program. PARTICIPANTS: Clients aged 65-95 (n=42) and their Home Care Aide (HCA) (n=32) were randomly assigned to a usual care and SFL intervention or usual care control group...
2017: Aging and Society: An Interdisciplinary Journal
https://www.readbyqxmd.com/read/27148160/public-knowledge-and-attitude-toward-essential-tremor-a-questionnaire-survey
#18
Sherif Shalaby, Jeffrey Indes, Benison Keung, Christopher H Gottschalk, Duarte Machado, Amar Patel, Daphne Robakis, Elan D Louis
BACKGROUND: Public awareness of and attitude toward disease is an important issue for patients. Public awareness of essential tremor (ET) has never been studied. METHODS: We administered a 10-min, 31-item questionnaire to 250 consecutive enrollees. These included three samples carefully chosen to have a potential range of awareness of ET: 100 individuals ascertained from a vascular disease clinic, 100 individuals from a general neurology clinic, and 50 Parkinson's disease (PD) patients...
2016: Frontiers in Neurology
https://www.readbyqxmd.com/read/26994856/how-the-frailty-index-may-support-the-allocation-of-health-care-resources-an-example-from-the-incur-study
#19
Matteo Cesari, Nadege Costa, Emiel O Hoogendijk, Bruno Vellas, Marco Canevelli, Mario Ulises Pérez-Zepeda
BACKGROUND: The Frailty Index (FI), proposed by Rockwood and Mitniski, measures the deficits accumulation occurring with aging, and can be generated from the results of a comprehensive clinical assessment. Its construct (based on pure arithmetical assumptions) may represent a unique feature for supporting unbiased comparisons among clinical facilities/services. OBJECTIVE: To propose an example depicting how the FI may support health economic evaluations and provide insights for public health...
May 1, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/26812520/validity-reliability-and-feasibility-of-tools-to-identify-frail-older-patients-in-inpatient-hospital-care-a-systematic-review
#20
REVIEW
R M J Warnier, E van Rossum, E van Velthuijsen, W J Mulder, J M G A Schols, G I J M Kempen
BACKGROUND: The objective of this study is to identify and review screening tools for frailty in older adults admitted to inpatient hospital care with respect to their validity, reliability and feasibility. METHODS: Studies were identified through systematically searching PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase and PsycINFO and screening reference lists till June 2014. Papers dealing with screening tools aimed at identifying frail older patients in in-hospital care, and including information about validity, reliability or feasibility, were included in the review...
February 2016: Journal of Nutrition, Health & Aging
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