keyword
https://read.qxmd.com/read/38615213/pneumothorax-pneumomediastinum-and-subcutaneous-emphysema-as-respiratory-complications-of-covid-19
#1
JOURNAL ARTICLE
Prabhat Rawal, Surendra Man Shrestha, Anju Gurung, Dipesh Poudel
BACKGROUND: Pneumothorax, pneumomediastinum and subcutaneous emphysema are respiratory complications of Coronavirus disease 2019 occurring with noteworthy frequency in patients especially with severe disease. They can be life-threatening and often complicate patient managment. METHODS: This was a retrospective, observational study of patients admitted in Nepal Armed Police Force hospital from 13/05/2020 to 28/12/2021 diagnosed with pneumothorax, pneumomediastinum or subcutaneous emphysema singly or in combination...
March 22, 2024: Journal of Nepal Health Research Council
https://read.qxmd.com/read/38602097/transcatheter-patent-ductus-arteriosus-closure-in-premature-infants-requiring-high-frequency-ventilation
#2
JOURNAL ARTICLE
Stephen T Dalby, Sherry E Courtney, Megha Sharma, Michael J Angtuaco
Transcatheter closure has become a common treatment method for patent ductus arteriosus in premature infants at many centres; however, many remain uncertain about the ability to perform the procedure in the catheterisation laboratory for infants requiring high-frequency ventilation. This study presents our centre's experience following the implementation of neonatal ventilatory guidelines, which resulted in 100% procedural success without any procedural or respiratory adverse events.
April 11, 2024: Cardiology in the Young
https://read.qxmd.com/read/38590298/effects-of-unilateral-superimposed-high-frequency-jet-ventilation-on-porcine-hemodynamics-and-gas-exchange-during-one-lung-flooding
#3
JOURNAL ARTICLE
Thomas Lesser, Frank Wolfram, Conny Braun, Reiner Gottschall
BACKGROUND: Superimposed high-frequency jet ventilation (SHFJV) is suitable for respiratory motion reduction and essential for effective lung tumor ablation. Fluid filling of the target lung wing one-lung flooding (OLF) is necessary for therapeutic ultrasound applications. However, whether unilateral SHFJV allows adequate hemodynamics and gas exchange is unclear. AIM: To compared SHFJV with pressure-controlled ventilation (PCV) during OLF by assessing hemodynamics and gas exchange in different animal positions...
March 20, 2024: World Journal of Experimental Medicine
https://read.qxmd.com/read/38584174/bilateral-thoracotomy-for-horseshoe-lung-complicated-with-severe-aspergilloma-a-case-report
#4
JOURNAL ARTICLE
Chihiro Kagohashi, Yasuyuki Kurihara, Mariko Hanafusa, Kenichi Okubo
BACKGROUND: Horseshoe lung is a rare congenital malformation in which the lung protrudes from the mediastinum to the other side. Owing to the high frequency of other fatal cardiovascular complications, it is often diagnosed in childhood and rarely unnoted until adulthood. We report a case of horseshoe lung in an older patient who underwent thoracotomy. CASE PRESENTATION: The patient was a 69-year-old man with chronic obstructive pulmonary disease (COPD) and a history of heavy smoking...
April 8, 2024: Surgical Case Reports
https://read.qxmd.com/read/38576961/meconium-aspiration-syndrome-from-pathophysiology-to-treatment
#5
REVIEW
Gianluca Dini, Sara Ceccarelli, Federica Celi, Carla Maria Semeraro, Paolo Gorello, Alberto Verrotti
Meconium aspiration syndrome (MAS) is a clinical condition characterized by respiratory distress in neonates born through meconium-stained amniotic fluid (MSAF). Despite advances in obstetric practices and perinatal care, MAS remains an important cause of morbidity and mortality in term and post-term newborns. Since the 1960s, there have been significant changes in the perinatal and postnatal management of infants born through MSAF. Routine endotracheal suctioning is no longer recommended in both vigorous and non-vigorous neonates with MSAF...
April 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38576872/development-of-an-artificial-intelligence-based-occupational-noise-induced-hearing-loss-early-warning-system-for-mine-workers
#6
JOURNAL ARTICLE
Milka C I Madahana, John E D Ekoru, Ben Sebothoma, Katijah Khoza-Shangase
INTRODUCTION: Occupational Noise Induced Hearing Loss (ONIHL) is one of the most prevalent conditions among mine workers globally. This reality is due to mine workers being exposed to noise produced by heavy machinery, rock drilling, blasting, and so on. This condition can be compounded by the fact that mine workers often work in confined workspaces for extended periods of time, where little to no attenuation of noise occurs. The objective of this research work is to present a preliminary study of the development of a hearing loss, early monitoring system for mine workers...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38569949/particle-characterization-in-commercial-buildings-a-cross-sectional-study-in-40-offices-in-singapore
#7
JOURNAL ARTICLE
Zuraimi Sultan, Li Jiayu, Jovan Pantelic, Stefano Schiavon
There is a knowledge gap in understanding how existing office buildings are protecting occupants from exposure to particles from both indoor and outdoor sources. We report a cross-sectional study involving weekly measurements of size-resolved indoor and outdoor particle concentrations in forty commercial building offices in Singapore. The outdoor and indoor particles size distributions were single mode with daytime peak number concentrations at 36.5 nm and 48.7 nm. Outdoor concentrations were significantly greater than indoors for all particle diameters...
April 1, 2024: Science of the Total Environment
https://read.qxmd.com/read/38558988/cb-1-cannabinoid-receptor-agonists-induce-acute-respiratory-depression-in-awake-mice
#8
Joshua Watkins, Petra Aradi, Rachel Hahn, Istvan Katona, Ken Mackie, Alexandros Makriyannis, Andrea G Hohmann
Recreational use of synthetic cannabinoid agonists (i.e., "Spice" compounds) that target the Cannabinoid Type 1 receptor (CB 1 ) can cause respiratory depression in humans. However, Δ 9 -tetrahydrocannabinol (THC), the major psychoactive phytocannabinoid in cannabis, is not traditionally thought to interact with CNS control of respiration, based largely upon sparse labeling of CB1 receptors in the medulla and few reports of clinically significant respiratory depression following cannabis overdose. The respiratory effects of CB 1 agonists have rarely been studied in vivo , suggesting that additional inquiry is required to reconcile the conflict between conventional wisdom and human data...
March 13, 2024: bioRxiv
https://read.qxmd.com/read/38556386/neonatal-high-frequency-ventilation-current-trends-and-future-directions
#9
JOURNAL ARTICLE
Sherry E Courtney, Anton H van Kaam, J Jane Pillow
High frequency ventilation (HFV) in neonates has been in use for over forty years. Some early HFV ventilators are no longer available, but high frequency oscillatory ventilation (HFOV) and jet ventilators (HFJV) continue to be commonly employed. Advanced HFOV models available outside of the United States are much quieter and easier to use, and are available as options on many conventional ventilators, providing important improvements such as tidal volume measurement and targeting. HFJV excels in treating air leak and non-homogenous lung disease and is often used for other diseases as well...
March 23, 2024: Seminars in Perinatology
https://read.qxmd.com/read/38552421/safety-of-cricotracheostomy-with-skin-and-tracheal-membrane-flaps-for-severe-covid-19-patients
#10
JOURNAL ARTICLE
Kosuke Tochigi, Hikaru Sakamoto, Kazuhiro Omura, Hisashi Kessoku, Teppei Takeda, Ryoji Oguro, Hiromi Kojima, Yasuhiro Tanaka
OBJECTIVE: Airway surgery is performed for COVID-19 patients who require long-term tracheal intubation and mechanical ventilation. Tracheostomy sometimes causes postoperative complications represented by bleeding at a relatively high rate in COVID-19 patients. As an alternative surgical procedure to tracheostomy, cricotracheostomy may reduce these complications, but few studies have examined its safety. METHODS: Data were retrospectively collected for sixteen COVID-19 patients (11 underwent tracheostomy, 5 underwent modified cricotracheostomy)...
March 28, 2024: Auris, Nasus, Larynx
https://read.qxmd.com/read/38547388/physiological-factors-associated-with-unsatisfied-inspiration-at-peak-exercise-in-healthy-adults
#11
JOURNAL ARTICLE
Olivia N Ferguson, Reid A Mitchell, Michele R Schaeffer, Andrew H Ramsook, Kyle G P J M Boyle, Satvir S Dhillon, Julia Zhang, Alanna S Hind, Dennis Jensen, Jordan A Guenette
INTRODUCTION: Contrary to common belief, a growing body of evidence suggests that unsatisfied inspiration (UI), an inherently uncomfortable quality of dyspnea, is experienced by ostensibly healthy adults during high-intensity exercise. Based on our understanding of the mechanisms of UI among people with chronic respiratory conditions, this analysis tested the hypothesis that the experience of UI at peak exercise in young, healthy adults reflects the combination of high ventilatory demand and critical inspiratory constraints...
March 28, 2024: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/38545090/efficacy-of-oral-20-hydroxyecdysone-bio101-a-mas-receptor-activator-in-adults-with-severe-covid-19-cova-a%C3%A2-randomized-placebo-controlled-phase-2-3-trial
#12
JOURNAL ARTICLE
Suzana Margareth Lobo, Gaétan Plantefève, Girish Nair, Adilson Joaquim Cavalcante, Nara Franzin de Moraes, Estevao Nunes, Otis Barnum, Claudio Marcel Berdun Stadnik, Maria Patelli Lima, Muriel Lins, Ludhmila Abrahao Hajjar, Christopher Lipinski, Shaheen Islam, Fabiano Ramos, Tiago Simon, Jean-Benoît Martinot, Thomas Guimard, Arnaud Desclaux, Bertrand Lioger, Fernando Carvalho Neuenschwander, Bruno DeSouza Paolino, Alpesh Amin, Samuel Amil Acosta, Daniel Forde Dilling, Edgardo Cartagena, Brian Snyder, Edouard Devaud, Ana Karolina Barreto Berselli Marinho, Suzana Tanni, Patricia Medeiros Milhomem Beato, Stephan De Wit, Vani Selvan, Jeffrey Gray, Ricardo Fernandez, Valérie Pourcher, Lee Maddox, Richard Kay, Anait Azbekyan, Mounia Chabane, Cendrine Tourette, Luis Everton Esmeraldino, Pierre J Dilda, René Lafont, Jean Mariani, Serge Camelo, Sandrine Rabut, Samuel Agus, Stanislas Veillet, Waly Dioh, Rob van Maanen, Capucine Morelot-Panzini
BACKGROUND: SARS-CoV-2 binding to ACE2 is potentially associated with severe pneumonia due to COVID-19. The aim of the study was to test whether Mas-receptor activation by 20-hydroxyecdysone (BIO101) could restore the Renin-Angiotensin System equilibrium and limit the frequency of respiratory failure and mortality in adults hospitalized with severe COVID-19. METHODS: Double-blind, randomized, placebo-controlled phase 2/3 trial. Randomization: 1:1 oral BIO101 (350 mg BID) or placebo, up to 28 days or until an endpoint was reached...
February 2024: EClinicalMedicine
https://read.qxmd.com/read/38538009/albuterol-delivery-via-in-line-intrapulmonary-percussive-ventilation-superimposed-on-conventional-mechanical-ventilation-in-an-adult-lung-model
#13
JOURNAL ARTICLE
Takashi Karashima, Yuka Mimura-Kimura, Yusuke Mimura
Background: Intrapulmonary percussive ventilation (IPV) is frequently used for airway clearance, together with delivery of aerosols containing medications. Drug delivery via IPV alone increases with decreasing percussion frequency and correlates with tidal volume (VT ) while drug delivery via IPV during conventional mechanical ventilation (IPV/CMV) is not well characterized. We hypothesized that drug delivery via IPV/CMV would take place differently from that via IPV alone due to control of ventilation by CMV...
March 27, 2024: Respiratory Care
https://read.qxmd.com/read/38532926/combined-frequency-domain-near-infrared-spectroscopy-and-diffuse-correlation-spectroscopy-system-for-comprehensive-metabolic-monitoring-of-inspiratory-muscles-during-loading
#14
JOURNAL ARTICLE
Carlos A Gómez, Laurent Brochard, Ewan C Goligher, Dmitry Rozenberg, W Darlene Reid, Darren Roblyer
SIGNIFICANCE: Mechanical ventilation (MV) is a cornerstone technology in the intensive care unit as it assists with the delivery of oxygen in critically ill patients. The process of weaning patients from MV can be long and arduous and can lead to serious complications for many patients. Despite the known importance of inspiratory muscle function in the success of weaning, current clinical standards do not include direct monitoring of these muscles. AIM: The goal of this project was to develop and validate a combined frequency domain near-infrared spectroscopy (FD-NIRS) and diffuse correlation spectroscopy (DCS) system for the noninvasive characterization of inspiratory muscle response to a load...
March 2024: Journal of Biomedical Optics
https://read.qxmd.com/read/38525765/adverse-outcomes-of-patients-with-non-ventilator-associated-hospital-acquired-pneumonia-nvhap-a-single-centre-cohort-study
#15
JOURNAL ARTICLE
Enrica Amodio, Peter W Schreiber, Mirjam Faes Hesse, Aline Wolfensberger
Non-ventilator associated hospital-acquired pneumonia (nvHAP) is a common nosocomial infection, but little is known about the outcomes of patients with nvHAP and the risk factors for adverse outcomes. In this retrospective study conducted in a Swiss tertiary care centre, adverse outcomes like in-hospital mortality, intensive care unit (ICU) admission, and mechanical ventilation, both all-cause and nvHAP-associated, were investigated. Of 244 patients with nvHAP, 72 (30%) died, 35 (14%) deaths were attributed to nvHAP...
March 13, 2024: Infectious Disease Reports
https://read.qxmd.com/read/38506028/-acute-and-chronic-rhinosinusitis-age-characteristics
#16
JOURNAL ARTICLE
S V Ryazantsev, I M Kirichenko, E L Savlevich, V I Popadyuk, N S Kozlova, A I Chernolev
Children's and adults' rhinosinusitis are two diseases that have both similarities and differences in anatomy, epidemiology, causes, pathogenesis, diagnosis and treatment. At the same rhinosinusitis is one of the most common in otorhinolaryngology's practice, both in children and adults. The of adults paranasal sinuses (PNS) anatomy differs from children's PNS anatomy. Although ostiomeatal complex occlusion is recognized as a major cause of poor ventilation and drainage of the adult paranasal sinuses, it does not have a strong effect on pediatric rhinosinusitis, but adenoids play a key role...
2024: Vestnik Otorinolaringologii
https://read.qxmd.com/read/38501054/characteristics-and-outcomes-of-coronavirus-disease-2019-among-pregnant-women-in-saudi-arabia-a-retrospective-study
#17
JOURNAL ARTICLE
Amani Abdelmola, Osama Albasheer, Atyaf A Kariri, Fatimah M Akkam, Rafeef A Hakami, Shahd A Essa, Fawziah M Jali
BACKGROUND: Pregnancy-related coronavirus disease 2019 infection ranges from asymptomatic to very serious illness. This study aimed to determine the impact of the COVID-19 infection on pregnant women in the Jazan region of Saudi Arabia. METHODS: Retrospective observational study of women who had COVID-19 positive test in pregnancy admitted in King Fahd Hospital, Abu Arish General Hospital, and Sabya General Hospital, Jazan, Saudi Arabia during the period between March 2020 and March 2022...
2024: International Journal of Women's Health
https://read.qxmd.com/read/38498685/lower-urinary-tract-symptoms-in-a-prospective-cohort-of-covid-19-survivors
#18
JOURNAL ARTICLE
Cristiano M Gomes, Marcelo Hisano, Julia D Souza, João Victor T Henriques, Jose de Bessa, Julyana Moromizato, Thulio Bosi, Rachel Mazoni, João Gismondi, Bruno Camargo, Zein M Sammour, Homero Bruschini, Linamara R Battistella, William C Nahas
PURPOSE: To analyze the prevalence of lower urinary tract symptoms (LUTS) in patients who survived moderate and severe forms of COVID-19 and the risk factors for LUTS six months after hospitalization. MATERIALS AND METHODS: In this prospective cohort study, patients were evaluated six months after hospitalization due to COVID-19. LUTS were assessed using the International Prostate Symptom Score. General health was assessed through the Hospital Anxiety and Depression Scale and the EQ5D-L5 scale, which evaluates mobility, ability to perform daily activities, pain and discomfort and completed a self-perception health evaluation...
March 3, 2024: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://read.qxmd.com/read/38482937/impact-of-weight-adjusted-high-frequency-low-tidal-volume-ventilation-and-atrial-pacing-in-lesion-metrics-in-high-power-short-duration-ablation-results-of-a-pilot-study
#19
JOURNAL ARTICLE
Fabricio Vassallo, Carlos Volponi, Christiano Cunha, Lucas Corcino, Eduardo Serpa, Aloyr Simoes, Dalbian Gasparini, Luiz Fernando Barbosa, Andre Schmidt
INTRODUCTION: Lesion size index (LSI) was introduced with the use of Tacticath™ and as a surrogate of lesion quality. The metric used to achieve the predetermined values involves combined information of contact force (CF), power and radiofrequency time. Rapid atrial pacing (RAP) and high-frequency low-tidal volume ventilation (HFLTV) independently or in combination improve catheter stability and CF and quality of lesions. Data of the impact of body weight adjusted HFLTV ventilation strategy associated with RAP in the lesion metrics still lacking...
March 14, 2024: Journal of Cardiovascular Electrophysiology
https://read.qxmd.com/read/38454542/the-toxic-stress-of-racism-and-its-relationship-to-frailty
#20
JOURNAL ARTICLE
Julie-Kathryn Graham, Danisha Jenkins, Kalie Iris, Morgan Knudsen, Christina Kelley
Significant morbidity and mortality from COVID-19-related illnesses have been observed among people of color within the United States. While theories involving healthcare inequity and political division have emerged to explain this observation, the role of chronic stress and inflammation is also being explored. Toxic stress is experienced disproportionately by race, ethnicity, and socioeconomic status and increases frailty and vulnerability to diseases such as COVID-19. C-reactive protein (CRP) is a biomarker associated with the inflammatory response that is typically elevated due to exposure to acute or chronic traumatic stress, as well as COVID-19...
March 7, 2024: Clinical Nursing Research
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