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https://www.readbyqxmd.com/read/29457522/a-high-prevalence-of-tmd-is-related-to-somatic-awareness-and-pain-intensity-among-healthy-dental-students
#1
Anna Lövgren, Catharina Österlund, Aurelija Ilgunas, Ewa Lampa, Fredrik Hellström
OBJECTIVE: Dental students have been identified as a group with high risks of developing both temporomandibular disorders (TMD) and psychosocial conditions. Our primary aim was to evaluate the cross-sectional prevalence of TMD diagnoses, as defined in the Diagnostic Criteria (DC)/TMD, among dental students. The secondary aim was to evaluate the prevalence and association of behavioural and psychosocial factors in relation to DC/TMD diagnoses. MATERIALS AND METHODS: The study was conducted among undergraduate dental students during the second semester of their third year at the Department of Odontology, Medical Faculty, Umeå University, Sweden...
February 18, 2018: Acta Odontologica Scandinavica
https://www.readbyqxmd.com/read/29457326/associations-between-adolescent-risk-for-restrictive-disordered-eating-and-long-term-outcomes-related-to-somatic-symptoms-body-mass-index-and-poor-well-being
#2
Evelina Landstedt, Anne Hammarström, A Kate Fairweather-Schmidt, Tracey Wade
OBJECTIVE: To date, no longitudinal, community-based studies have examined the association between disordered eating emerging in adolescence and long-term physical well-being. This study sought to explore the longitudinal associations between risk for restrictive disordered eating (DE-R; those not presenting with binge-purge symptoms) in adolescence and trajectories of functional somatic symptoms (FSS) and body mass index (BMI), and several indicators of poor physical well-being across early- to mid-adulthood, including medication, number of doctor visits, and sick leave...
February 18, 2018: British Journal of Health Psychology
https://www.readbyqxmd.com/read/29455021/effect-of-dopamine-receptor-d4-drd4-haplotypes-on-general-psychopathology-in-patients-with-eating-disorders
#3
Guillermo Gervasini, Luz M González, Carmen Gamero-Villarroel, Sonia Mota-Zamorano, Juan Antonio Carrillo, Isalud Flores, Angustias Garcia-Herráiz
Among the many candidate genes analyzed in eating disorder (ED) patients, those involved in dopaminergic functions may be of special relevance, as dopamine is known to play a significant role in feeding behavior, the distortion of body image, hyperactivity and reward and reinforcement processes. We aimed to determine the effect of functional polymorphisms and haplotypes in the Dopamine Receptor D4 (DRD4) gene on general psychopathological symptoms in ED patients. Two-hundred-and-seventy-three ED patients [199 with Anorexia Nervosa (AN) and 74 with Bulimia Nervosa (BN)] completed the SCL-90R inventory and were genotyped for four functional, clinically relevant DRD4 polymorphisms: three variants in the promoter region [120-bp tandem repeat (TR, long vs...
February 15, 2018: Gene
https://www.readbyqxmd.com/read/29452590/factors-associated-with-persistent-posttraumatic-stress-disorder-among-u-s-military-service-members-and-veterans
#4
Richard F Armenta, Toni Rush, Cynthia A LeardMann, Jeffrey Millegan, Adam Cooper, Charles W Hoge
BACKGROUND: Posttraumatic stress disorder (PTSD) can have long-term and far-reaching impacts on health and social and occupational functioning. This study examined factors associated with persistent PTSD among U.S. service members and veterans. METHODS: Using baseline and follow-up (2001-2013) questionnaire data collected approximately every 3 years from the Millennium Cohort Study, multivariable logistic regression was conducted to determine factors associated with persistent PTSD...
February 17, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29451340/therapeutic-neural-stem-cells-engineered-during-different-stages-of-reprogramming-reveal-varying-therapeutic-efficacies
#5
Deepak Bhere, Rajiv Kumar Khajuria, William T Hendriks, Antara Bandyopadhyay, Tugba Bagci-Onder, Khalid Shah
Stem cells are emerging as promising treatment strategies for several brain disorders and pathologies including brain tumors. In this study, we explored the potential of creating induced pluripotent stem cell (iPSC) derived therapeutic NSCs (ipNSC) by using either unmodified or gene-modified somatic cells and tested their fate and therapeutic efficacies in vitro and in vivo. We show that cells engineered in somatic state lose transgene-expression during the neural induction process, which is partially restored by HDAC inhibitor (i) treatment whereas cells engineered at the ipNSC state have sustained expression of transgenes...
February 16, 2018: Stem Cells
https://www.readbyqxmd.com/read/29449820/headache-and-alexithymia-in-children-and-adolescents-what-is-the-connection
#6
REVIEW
Giulia Natalucci, Noemi Faedda, Dario Calderoni, Rita Cerutti, Paola Verdecchia, Vincenzo Guidetti
Background: Headache is one of the most common complaints in children and adolescents and comorbidity rates are very high and the major associated diseases are depression, anxiety, atopic disorders, sleep, and behavioral disorders. In recent years, it has been highlighted that difficulties regulating emotions such as alexithymia have also been associated with diagnosis of somatization. Methods: We carried out a mini review analyzing the relation between alexithymia and primary headache (e.g., migraine and tension type headache) in children and adolescents by synthesizing the relevant studies in the literature on PubMed, PsycINFO, and Google Scholar...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29446817/depression-in-tunisian-type-2-diabetic-patients-prevalence-and-association-to-glycemic-control-and-to-treatment-compliance
#7
Faten Ellouze, Rahma Damak, Mehdi El Karoui, Haifa Mami, Mohamed Fadhel M'rad, Ghada Hamdi, Abdelmajid Abid
AIM: to study the prevalence of depression in type 2 diabetes and to seek for a relationship between glycemic control and treatment adherence. METHODS: This cross-sectional study was carried out at the outpatient department of the Tunis nutrition institute. A total of 100 diabetic patients followed for Type 2 diabetes were randomly recruited. We used a structured questionnaire to collect patients' socio-demographic, clinical and therapeutic data. The treatment adherence was assessed by using MAS, Glycemic control according to blood glucose and glycated hemoglobin (HbA1c) levels and depression and anxiety by administering a dialectal Arabic validated version of Hospital Anxiety and Depression Scale (HAD)...
March 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29446767/clapo-syndrome-identification-of-somatic-activating-pik3ca-mutations-and-delineation-of-the-natural-history-and-phenotype
#8
Lara Rodriguez-Laguna, Kristina Ibañez, Gema Gordo, Sixto Garcia-Minaur, Fernando Santos-Simarro, Noelia Agra, Elena Vallespín, Victoria E Fernández-Montaño, Rubén Martín-Arenas, Ángela Del Pozo, Héctor González-Pecellín, Rocío Mena, Inmaculada Rueda-Arenas, María V Gomez, Cristina Villaverde, Ana Bustamante, Carmen Ayuso, Víctor L Ruiz-Perez, Julián Nevado, Pablo Lapunzina, Juan C Lopez-Gutierrez, Victor Martinez-Glez
PurposeCLAPO syndrome is a rare vascular disorder characterized by capillary malformation of the lower lip, lymphatic malformation predominant on the face and neck, asymmetry, and partial/generalized overgrowth. Here we tested the hypothesis that, although the genetic cause is not known, the tissue distribution of the clinical manifestations in CLAPO seems to follow a pattern of somatic mosaicism.MethodsWe clinically evaluated a cohort of 13 patients with CLAPO and screened 20 DNA blood/tissue samples from 9 patients using high-throughput, deep sequencing...
February 15, 2018: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/29445425/mosaicism-for-gnas-methylation-defects-associated-with-pseudohypoparathyroidism-type-1b-arose-in-early-post-zygotic-phases
#9
Francesca Marta Elli, Paolo Bordogna, Maura Arosio, Anna Spada, Giovanna Mantovani
Background: Pseudohypoparathyroidism type 1B (PHP1B; MIM#603233) is a rare imprinting disorder (ID), associated with the GNAS locus, characterized by parathyroid hormone (PTH) resistance in the absence of other endocrine or physical abnormalities. Sporadic PHP1B cases, with no known underlying primary genetic lesions, could represent true stochastic errors in early embryonic maintenance of methylation. Previous data confirmed the existence of different degrees of methylation defects associated with PHP1B and suggested the presence of mosaicism, a phenomenon already described in the context of other IDs...
2018: Clinical Epigenetics
https://www.readbyqxmd.com/read/29445280/the-differences-between-patients-with-panic-disorder-and-healthy-controls-in-psychophysiological-stress-profile
#10
Antonia Kotianova, Michal Kotian, Milos Slepecky, Michaela Chupacova, Jan Prasko, Ingrid Tonhajzerova
Background: Alarming somatic symptoms, in particular, cardiovascular symptoms, are the characteristic feature of panic attacks. Increased cardiac mortality and morbidity have been found in these patients. Power spectral analysis of electrocardiogram R-R intervals is known to be a particularly successful tool in the detection of autonomic instabilities in various clinical disorders. Our study aimed to compare patients with panic disorder and healthy controls in heart rate variation (HRV) parameters (very-low-frequency [VLF], low-frequency [LF], and high-frequency [HF] band components of R-R interval) in baseline and during the response to the mental task...
2018: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29439279/-comorbid-mental-disorders-in-gastroenterology-and-hepatology-prevalence-and-psychosocial-needs-in-tertiary-care
#11
Alexander Niecke, Hanna Lemke, Tobias Goeser, Martin Hellmich, Frank Vitinius, Christian Albus
BACKGROUND: In the field of gastroenterology and hepatology, associations and interactions with comorbid mental disorders are often described, but there is currently a lack of methodologically high-quality studies on prevalence and the need for care. The aim of the study was to take account of this shortcoming. METHODS: Prospective, monocentric, cross-sectional study of a representative sample of inpatients at a university hospital. A total of 308 participants were examined for the presence of 8 frequent psychological syndromes with a validated questionnaire (PHQ-D)...
February 13, 2018: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/29437867/evidence-for-genetic-anticipation-in-von-hippel-lindau-syndrome
#12
Laura Aronoff, David Malkin, Kalene van Engelen, Bailey Gallinger, Jonathan Wasserman, Raymond H Kim, Anita Villani, M Stephen Meyn, Harriet Druker
BACKGROUND: von Hippel-Lindau (vHL) syndrome is a rare autosomal-dominant disorder that confers a lifelong risk for developing both benign and malignant tumours in multiple organs. Recent evidence suggests that vHL may exhibit genetic anticipation (GA). The aim of this study was to determine if GA occurs in vHL, and if telomere shortening may be a factor in GA. METHODS: A retrospective chart review of vHL families seen at The Hospital for Sick Children between 1984 and 2016 was performed...
February 7, 2018: Journal of Medical Genetics
https://www.readbyqxmd.com/read/29436489/-cryptogenic-drop-attacks-revisited-evidence-of-overlap-with-functional-neurological-disorder
#13
Ingrid Hoeritzauer, Alan J Carson, Jon Stone
OBJECTIVE: In their 1973 BMJ paper 'Cryptogenic Drop Attacks', Stevens and Matthews described 40, mostly middle-aged, female patients with drop attacks of unknown cause. Although clinically common, there has been little on this topic since. We aimed to determine clinical features, comorbidity and outcome of patients with drop attacks. METHODS: We carried out a retrospective review of patients with cryptogenic drop attacks seen consecutively by one clinician (JS) between 2006 and 2016...
February 7, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29433889/psychiatric-disease-in-surgically-treated-colorectal-cancer-patients
#14
Vanessa P Ho, Emily Steinhagen, Kelsey Angell, Suparna M Navale, Nicholas K Schiltz, Andrew P Reimer, Elizabeth A Madigan, Siran M Koroukian
BACKGROUND: Underlying psychiatric conditions may affect outcomes of surgical treatment for colorectal cancer (CRC) because of complex clinical presentation and treatment considerations. We hypothesized that patients with psychiatric illness (PSYCH) would have evidence of advanced disease at presentation, as manifested by higher rates of colorectal surgery performed in the presence of obstruction, perforation, and/or peritonitis (OPP-surgery). MATERIALS AND METHODS: Using data from the 2007-2011 National Inpatient Sample, we identified patients with a diagnosis of CRC undergoing colorectal surgery...
March 2018: Journal of Surgical Research
https://www.readbyqxmd.com/read/29432570/insomnia-perchance-a-dream-results-from-a-nrem-rem-sleep-awakening-study-in-good-sleepers-and-patients-with-insomnia
#15
Bernd Feige, Svetoslava Nanovska, Chiara Baglioni, Benedict Bier, Laura Cabrera, Sarah Diemers, Maximilian Quellmalz, Markus Siegel, Ireni Xeni, Andras Szentkiralyi, John-Peter Doerr, Dieter Riemann
Study Objectives: Insomnia disorder (ID) is a frequent sleep disorder coupled with increased risks for somatic and mental illness. While subjective complaints are severe, polysomnography (PSG) parameters show only modest differences between groups. REM sleep as the most aroused sleep state may be especially vulnerable to be perceived as wake. To directly assess possible differences, we determined auditory waking thresholds and sleep perception in ID patients and healthy control subjects (GSC) in N2 and REM sleep...
February 8, 2018: Sleep
https://www.readbyqxmd.com/read/29432506/eating-habits-and-nutritional-status-of-patients-with-affective-disorders-and-schizophrenia
#16
Ewa Stefańska, Magdalena Lech, Agnieszka Wendołowicz, Beata Konarzewska, Napoleon Waszkiewicz, Lucyna Ostrowska
OBJECTIVES: The aim of the study was to assess the nutritional value of the food intake in the group of men and women suffering from recurrent affective disorders and schizophrenia, and also to determine the relation between selected nutritional parameters with anthropometric indices defining the nutritional status of the subjects. METHODS: 219 persons participated in the study (61 patients with recurrent depressive disorders, 60 patients with schizophrenia and 98 healthy volunteers)...
December 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29432505/the-use-of-eeg-biofeedback-neurofeedback-in-psychiatric-rehabilitation
#17
REVIEW
Renata Markiewcz
The aim of the systematic review was to evaluate the use of EEG Biofeedback/Neurofeedback in patients treated for mental disorders. The review covered publications analyzing influences and effects of therapy in patients receiving psychiatric treatment based on EEG Biofeedback/Neurofeedback. Selection of publications was made by searching PubMed and Scopus databases. 328 records concerning applications of the presented method were identified in total, including 84 records for patients diagnosed with mental disorders...
December 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29431859/adverse-childhood-experiences-and-depressive-symptomatology-among-pregnant-women
#18
Katja Ångerud, Eva-Maria Annerbäck, Tanja Tydén, Santosh Boddeti, Per Kristiansson
INTRODUCTION: Adverse childhood experiences (ACE) result in somatic and mental health disturbances. Its influence on antenatal depression is scarcely studied. This study examined the association between experience of ACE and antenatal depressive symptomatology. MATERIAL AND METHODS: 1257 women from 172 antenatal clinics in Sweden were surveyed during pregnancy and one year after delivery. Demographics, previous medical history and Edinburgh Postpartum Depression Scale (EPDS) were collected in pregnancy and postpartum and ACE one year postpartum...
February 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29430590/patterns-of-health-care-service-utilization-by-individuals-with-mental-health-problems-a-predictive-cluster-analysis
#19
Béatrice Simo, Jean-Marie Bamvita, Jean Caron, Marie-Josée Fleury
This study aimed at identifying and characterizing clusters of mental health service users based on various characteristics in a sample of individuals with mental health problems. Data were collected in the epidemiological catchment area of South-West Montreal, Quebec in 2011 and 2014. Among the 746 participants who reported experiencing a mental health problem (high psychological distress and/or a mental disorder), 29% had used mental health services. A Two-Step cluster analysis was carried out to generate participant profiles based on their visit to mental health professional...
February 12, 2018: Psychiatric Quarterly
https://www.readbyqxmd.com/read/29428582/predicting-suicidal-ideation-in-primary-care-an-approach-to-identify-easily-assessable-key-variables
#20
Pascal Jordan, Meike C Shedden-Mora, Bernd Löwe
OBJECTIVE: To obtain predictors of suicidal ideation, which can also be used for an indirect assessment of suicidal ideation (SI). To create a classifier for SI based on variables of the Patient Health Questionnaire (PHQ) and sociodemographic variables, and to obtain an upper bound on the best possible performance of a predictor based on those variables. METHODS: From a consecutive sample of 9025 primary care patients, 6805 eligible patients (60% female; mean age = 51...
February 2, 2018: General Hospital Psychiatry
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