Yury Malyshev, Petr Neuzil, Jan Petru, Moritoshi Funasako, Pavel Hala, Karel Kopriva, Christopher Schneider, Anitha Achyutha, Annelies Vanderper, Daniel Musikantow, Mohit Turagam, Srinivas R Dukkipati, Vivek Y Reddy
BACKGROUND: In treating atrial fibrillation, pulsed-field ablation (PFA) has comparable efficacy to conventional thermal ablation, but with important safety advantages: no esophageal injury or pulmonary vein stenosis, and rare phrenic nerve injury. However, when PFA is delivered in proximity to coronary arteries using a pentaspline catheter, which generates a broad electrical field, severe vasospasm can be provoked. OBJECTIVES: The authors sought to study the vasospastic potential of a focal PFA catheter with a narrower electrical field and develop a preventive strategy with nitroglycerin...
February 7, 2024: JACC. Clinical Electrophysiology