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Nili Avni-Magen, Daniel Elad, Michael Friedman, Irith Gati, Elizabeth Kaufman, Eran Lavy
In November 2004, an adult male siamang (Hylobates syndactylus) from The Tisch Family Zoological Gardens-Jerusalem Biblical Zoo (Israel) presented with skin lesions on various body parts. Lesions consisted of alopecia and dry, crusty areas of hyperkeratosis. A diagnosis of dermatophytosis due to Microsporum canis was determined by fungal culture of skin scraping taken from the edge of several lesions. Treatment with various oral and topical antifungal agents such as griseofluvin, itraconozole, and lufenuron resulted in the resolution of most lesions and a decrease in size of the single remaining lesion, which continued to be culture positive for M...
March 2008: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
Anand Balakrishnan, Bhagwant D Rege, Gordon L Amidon, James E Polli
The objective of this study was to assess the contributions of surfactant-mediated solubility and micellar diffusivity on the ability of surfactant to enhance drug dissolution. The following model was derived to predict the degree to which surfactants enhance griseofulvin dissolution: phi = 1 + (fm/ff).((D(D-M)2/3)/(DD2/3)) where phi is the degree of surfactant-mediated dissolution enhancement, fm is the fraction of the drug in micelle, and ff is the fraction of free drug, and DD and D(D-M) are the diffusivities of free drug and drug-loaded micelles, respectively...
August 2004: Journal of Pharmaceutical Sciences
No abstract text is available yet for this article.
May 4, 1964: JAMA: the Journal of the American Medical Association
F A Edgson
No abstract text is available yet for this article.
January 17, 1970: Veterinary Record
Ia I Blizniuk, K A Dzhincharadze
No abstract text is available yet for this article.
October 1977: Veterinariia
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