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Stroke young adults

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https://www.readbyqxmd.com/read/28913687/non-atherosclerotic-vascular-disease-in-women
#1
REVIEW
Lee Joseph, Esther S H Kim
Takayasu arteritis, fibromuscular dysplasia (FMD), spontaneous arterial dissection, Raynaud's phenomenon, and chilblains are vascular conditions that are associated with an increased predisposition in women and are often underdiagnosed. Takayasu arteritis has an incidence rate of 2.6 cases per million individuals per year in the USA and predominantly affects women of childbearing age. HLA-B5 genetic locus is linked with Takayasu arteritis susceptibility. Methods to determine active disease are limiting; currently utilized clinical and imaging findings and laboratory tests are of limited value for this purpose...
September 14, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28911137/cardiovascular-diseases-and-life-expectancy-in-adults-with-type-2-diabetes-a-korean-national-sample-cohort-study
#2
Yu Mi Kang, Yun Kyung Cho, Seung Eun Lee, Joong-Yeol Park, Woo Je Lee, Ye-Jee Kim, Chang Hee Jung
Objective: Although type 2 diabetes is a strong risk factor for cardiovascular disease and mortality, information on its association with mortality and life expectancy according to cardiovascular comorbidities is limited, especially in Asia. Thus, this study assessed mortality and reductions in life expectancy associated with cardiometabolic multimorbidity. Design and Methods: A total of 569,831 participants older than 30 years from Korean National Health Insurance Service-National Sample Cohort were enrolled between 2002 and 2006 and followed for a median of 12...
September 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28902897/testing-the-effects-of-sensory-stimulation-as-a-collateral-based-therapeutic-for-ischemic-stroke-in-c57bl-6j-and-cd1-mouse-strains
#3
Aneeka M Hancock, Ron D Frostig
Utilizing a rat model of ischemic stroke, we have previously shown that sensory stimulation can completely protect rats from impending ischemic damage of cortex if this treatment is delivered within the first two hours post-permanent middle cerebral artery occlusion (pMCAo). The current study sought to extend our findings in rats to mice, which would allow new avenues of research not available in rats. Thus, young adult C57BL/6J and CD1 mice were tested for protection from ischemic stroke with the same protective sensory stimulation-based treatment...
2017: PloS One
https://www.readbyqxmd.com/read/28894740/increased-whole-cerebellar-serotonin-in-aged-c57bl-6-mice
#4
Nicholas W DeKorver, Dustin Lichty, Marieke van der Hart, Arash Rassoulpour, Stephen J Bonasera
Mobility and locomotor impairments have high prevalence, morbidity, and significant mortality in older adult populations. Cerebellar functional changes have been implicated in the pathogenesis of these age-related mobility and gait deficits unrelated to stroke, Parkinson's disease, or degenerative joint disease. We thus examined total cerebellar glutamate, glutamine, GABA, glycine, dopamine, norepinephrine, tryptophan, serotonin, alanine, threonine, and asparagine content from male 2-3-month (young, n = 6) and 21-24-month-old (aged, n = 6) C57BL/6 mice...
2017: Matters (Zur)
https://www.readbyqxmd.com/read/28892806/a-novel-missense-gla-mutation-p-g35v-detected-in-hemodialysis-screening-leads-to-severe-systemic-manifestations-of-fabry-disease-in-men-and-women
#5
Valeria Soares Pigozzi Veloso, Thiago Lacerda Ataides, Maria Eugênia Fernandes Canziani, Mariana Pigozzi Veloso, Nilzio Antônio da Silva, Daniela Veit Barreto, Edna Regina Silva Pereira, Luiz Antonio Ribeiro de Moura, Fellype Carvalho Barreto
BACKGROUND/AIMS: Fabry disease (FD), an X-linked lysosomal storage disorder, leads to accumulation of globotriaosylceramide. Screening in dialysis patients may identify genetic variants of unknown clinical significance. We aimed to characterize the pathogenicity of a novel GLA gene mutation identified during hemodialysis screening and the histologic findings of early Fabry nephropathy. METHODS: One out of 108 male hemodialysis patients screened for FD presented low α-galactosidase A activity...
September 12, 2017: Nephron
https://www.readbyqxmd.com/read/28889789/blood-pressure-evolution-in-young-patients-with-acute-ischemic-stroke-a-new-model-for-understanding-the-natural-course-of-spontaneous-hypertension
#6
Pablo Bonardo, Fatima Pantiu, Anibal Chertcoff, Luciana Leon Cejas, Sol Pacha, Claudia Uribe Roca, Glenda Ernst, Manuel Fernandez Pardal, Ricardo Reisin
BACKGROUND: Approximately 80% of patients suffering an acute ischemic stroke develop transient hypertension. The physiopathological mechanism remains unclear. Due to the lack of vascular risk factors, young adults could be a useful model for understanding blood pressure (BP) evolution in this setting. METHODS: Patients between 18-55 years old admitted with an acute ischemic stroke were included. BP was evaluated during the following 48 h. Hypertension was defined as: systolic blood pressure (SBP) ≥ 140 mmHg or diastolic blood pressure (DBP) ≥ 90 mmHg...
September 9, 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/28872036/decision-making-for-gastrostomy-after-70-years-old-a-prospective-study-about-26-patients
#7
Angéline Mey, Amandine Devun, Marc Roussier, Régis Gonthier, Thomas Celarier
Management of undernutrition is based on young adults analysis. However, enteral nutrition is mainly discussed in the elderly. The aim of this study was to analyse factors related to laying gastrostomy, in geriatrics. A prospective, descriptive study, was conducted in the Loire department, from 2014 to 2016, in geriatric and palliative units. All patients over 70 years who had a theorical indication of gastrostomy were included. Decision-making process was analyzed from data affecting the reflection. Patients were followed for three months...
September 1, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/28871237/characteristics-and-outcomes-of-young-patients-with-first-ever-ischemic-stroke-compared-to-older-patients-the-national-acute-stroke-israeli-registry
#8
Miri Lutski, Inbar Zucker, Tamy Shohat, David Tanne
BACKGROUND: Nationwide data on the clinical profile and outcomes of ischemic stroke in younger adults are still scarce. Our aim was to analyze clinical characteristics and outcomes of young patients with first-ever ischemic stroke compared to older patients. METHODS: The National Acute Stroke ISraeli registry is a nationwide prospective hospital-based study performed triennially. Younger adults, aged 50 years and younger, were compared with patients, aged 51-84 years regarding risk factors, clinical presentation, stroke severity, stroke etiology, and outcomes...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28835475/stroke-and-methamphetamine-use-in-young-adults-a-review
#9
REVIEW
Julia M Lappin, Shane Darke, Michael Farrell
BACKGROUND: Methamphetamine use and stroke are significant public health problems. Strokes among people aged below 45 years are much less common than in older age groups but have significant mortality and morbidity. Methamphetamine is a putative cause of strokes among younger people. METHODS: A review of methamphetamine-related strokes was conducted. Bibliographic databases were searched until February 2017 for articles related to methamphetamine and stroke. Both haemorrhagic and ischaemic strokes were considered...
August 23, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28828467/longitudinal-care-for-young-adults-with-stroke
#10
Lester Y Leung, Emiliya Melkumova, David E Thaler
No abstract text is available yet for this article.
August 21, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28828465/association-of-childhood-body-mass-index-and-change-in-body-mass-index-with-first-adult-ischemic-stroke
#11
Line K Gjærde, Michael Gamborg, Lars Ängquist, Thomas C Truelsen, Thorkild I A Sørensen, Jennifer L Baker
Importance: The incidence of ischemic stroke among young adults is rising and is potentially due to an increase in stroke risk factors occurring at younger ages, such as obesity. Objectives: To investigate whether childhood body mass index (BMI) and change in BMI are associated with adult ischemic stroke and to assess whether the associations are age dependent or influenced by birth weight. Design, Setting, and Participants: This investigation was a population-based cohort study of schoolchildren born from 1930 to 1987, with follow-up through national health registers from 1977 to 2012 in Denmark...
August 21, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28820188/stroke-twist-in-artery-linked-to-stroke-in-young-adults
#12
Mitesh Patel
No abstract text is available yet for this article.
August 18, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28820187/cerebral-venous-thrombosis
#13
REVIEW
Suzanne M Silvis, Diana Aguiar de Sousa, José M Ferro, Jonathan M Coutinho
Cerebral venous thrombosis (CVT) is an important cause of stroke in young adults. Data from large international registries published in the past two decades have greatly improved our knowledge about the epidemiology, clinical manifestations and prognosis of CVT. The presentation of symptoms is highly variable in this disease, and can range from a patient seen at the clinic with a 1-month history of headache, to a comatose patient admitted to the emergency room. Consequently, the diagnosis of CVT is often delayed or overlooked...
August 18, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28817789/teach-our-children-stroke-education-for-indigenous-children-first-nations-ontario-canada-2009-2012
#14
Mary Ellen Hill, Pauline Bodnar, Robert Fenton, Brenda Mason, Grace Bandoh
BACKGROUND: Because of the heightened risk for stroke among indigenous people, we conducted this multiyear community case study from 2009 through 2012 to address stroke education needs among children aged 11 to 13 years residing in northern urban, rural, and remote First Nations in Ontario, Canada. The goal was to determine what young people understand about stroke and to develop an age-appropriate and culturally appropriate educational product. COMMUNITY CONTEXT: This project responded to First Nations requests that we educate their young people about the signs and symptoms of stroke and the need for early response...
August 17, 2017: Preventing Chronic Disease
https://www.readbyqxmd.com/read/28817502/stroke-related-disease-comorbidity-and-secondary-stroke-prevention-practices-among-young-stroke-survivors
#15
Gayenell S Magwood, Brandi M White, Charles Ellis
BACKGROUND: Although ischemic stroke incidence has been in decline over the past 60 years, the same has not been observed among individuals younger than 55 years. Recent reports have shown a substantial increase in young stroke incidence, yet little is known about young stroke survivors. OBJECTIVE: The aim of this study was to examine the disease comorbidity profile and secondary prevention practices in stroke survivors younger than 50 years. METHODS: This study used a retrospective data analysis of secondary stroke prevention practices among young stroke survivors using data from the 2015 National Health Interview Survey...
October 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/28815091/-spice-synthetic-marijuana-induced-acute-myocardial-infarction-a-case-series
#16
E Ul Haq, A Shafiq, A A Khan, A A Awan, S Ezad, W J Minteer, B Omar
Marijuana is the most widely abused "recreational" substance in the United States, with highest prevalence in young adults. It is reported to cause ischemic strokes, hepatitis, anxiety, and psychosis. Although it is associated with dose dependent tachycardia and can lead to coronary vasospasm, it has not been directly related to acute myocardial infarction (AMI). Marijuana induced coronary vasospasm can result in endothelial denudation at the site of a vulnerable atherosclerotic plaque in response to hemodynamic stressors, potentially causing an AMI...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28813787/clarification-of-muscle-synergy-structure-during-standing-up-motion-of-healthy-young-elderly-and-post-stroke-patients
#17
N Yang, Q An, H Yamakawa, Y Tamura, A Yamashita, K Takahashi, M Kinomoto, H Yamasaki, M Itkonen, F S Alnajjar, S Shimoda, H Asama, N Hattori, I Miyai
Standing-up motion is an important daily activity. It has been known that elderly and post-stroke patients have difficulty in performing standing-up motion. The standing-up motion is retrained by therapists to maximize independence of the elderly and post-stroke patients, but it is not clear how the elderly and post-stroke patients control their redundant muscles to achieve standing-up motion. This study employed the concept of muscle synergy to analyze how healthy young adults, healthy elderly people and post-stroke patients control their muscles...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28805343/rest-and-exercise-hemodynamic-and-metabolic-findings-in-active-duty-soldiers-referred-for-cardiac-catheterization-to-exclude-heart-disease-insights-from-past-invasive-cardiopulmonary-exercise-testing-using-multisensor-high-fidelity-catheters
#18
James A Watts, Faith R Kelly, Terry D Bauch, Joseph P Murgo, Bernard J Rubal
OBJECTIVE: This study describes results of iCPET from the past, which used submaximal stress and multisensor high-fidelity catheters to exclude heart disease in a unique population of young adults. BACKGROUND: There has been resurgence in comprehensive hemodynamic evaluation of complex cardiovascular patients. Although dynamic assessments during cardiac catheterization have become commonplace, there remains limited information regarding left and right heart hemodynamic changes during supine exercise in young adults...
May 8, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28803362/perceptuo-motor-planning-during-functional-reaching-after-stroke
#19
Margit Alt Murphy, Melanie C Baniña, Mindy F Levin
In healthy young adults, reaching movements are planned such that the initial grasp position on the object is modulated based on the final task goal. This perceptuo-motor coupling has been described as the end-state comfort effect. This study aimed to determine the extent to which visuo-perceptual and motor deficits, but not neglect, due to stroke impact end-state comfort measured as the grasp-height effect. Thirty-four older adults (17 controls, 17 chronic stroke) performed a functional goal-directed two-sequence task with each arm, consisting of reaching and moving a cylindrical object (drain plunger) from an initial to four target platform heights, standardized to body height, in a block randomized sequence...
August 12, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28762897/sudden-unexpected-death-caused-by-stroke-a-nationwide-study-among-children-and-young-adults-in-denmark
#20
Frederik Nybye Ågesen, Bjarke Risgaard, Sára Zachariasardóttir, Reza Jabbari, Thomas Hadberg Lynge, Ole Ingemann-Hansen, Gyda Lolk Ottesen, Jørgen Lange Thomsen, Stig Haunsø, Derk Wolfgang Krieger, Bo Gregers Winkel, Jacob Tfelt-Hansen
Background Stroke is the fifth leading cause of death in young individuals globally. Data on the burden of sudden death by stroke are sparse in the young. Aims The aim of this study was to report mortality rates, cause of death, stroke subtype, and symptoms in children and young adults who suffered sudden death by stroke. Methods We conducted a retrospective, nationwide study including all deaths within Danish borders between 2000-2009 and 2007-2009 in persons aged 1-35 years and 36-49 years, respectively. Two physicians identified all sudden death cases through review of all death certificates...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
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