keyword
MENU ▼
Read by QxMD icon Read
search

Stroke young adults

keyword
https://www.readbyqxmd.com/read/28805343/rest-and-exercise-hemodynamic-and-metabolic-findings-in-active-duty-soldiers-referred-for-cardiac-catheterization-to-exclude-heart-disease-insights-from-past-invasive-cardiopulmonary-exercise-testing-using-multisensor-high-fidelity-catheters
#1
James A Watts, Faith R Kelly, Terry D Bauch, Joseph P Murgo, Bernard J Rubal
OBJECTIVE: This study describes results of iCPET from the past, which used submaximal stress and multisensor high-fidelity catheters to exclude heart disease in a unique population of young adults. BACKGROUND: There has been resurgence in comprehensive hemodynamic evaluation of complex cardiovascular patients. Although dynamic assessments during cardiac catheterization have become commonplace, there remains limited information regarding left and right heart hemodynamic changes during supine exercise in young adults...
May 8, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28803362/perceptuo-motor-planning-during-functional-reaching-after-stroke
#2
Margit Alt Murphy, Melanie C Baniña, Mindy F Levin
In healthy young adults, reaching movements are planned such that the initial grasp position on the object is modulated based on the final task goal. This perceptuo-motor coupling has been described as the end-state comfort effect. This study aimed to determine the extent to which visuo-perceptual and motor deficits, but not neglect, due to stroke impact end-state comfort measured as the grasp-height effect. Thirty-four older adults (17 controls, 17 chronic stroke) performed a functional goal-directed two-sequence task with each arm, consisting of reaching and moving a cylindrical object (drain plunger) from an initial to four target platform heights, standardized to body height, in a block randomized sequence...
August 12, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28762897/sudden-unexpected-death-caused-by-stroke-a-nationwide-study-among-children-and-young-adults-in-denmark
#3
Frederik Nybye Ågesen, Bjarke Risgaard, Sára Zachariasardóttir, Reza Jabbari, Thomas Hadberg Lynge, Ole Ingemann-Hansen, Gyda Lolk Ottesen, Jørgen Lange Thomsen, Stig Haunsø, Derk Wolfgang Krieger, Bo Gregers Winkel, Jacob Tfelt-Hansen
Background Stroke is the fifth leading cause of death in young individuals globally. Data on the burden of sudden death by stroke are sparse in the young. Aims The aim of this study was to report mortality rates, cause of death, stroke subtype, and symptoms in children and young adults who suffered sudden death by stroke. Methods We conducted a retrospective, nationwide study including all deaths within Danish borders between 2000-2009 and 2007-2009 in persons aged 1-35 years and 36-49 years, respectively. Two physicians identified all sudden death cases through review of all death certificates...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/28755978/duration-of-isoflurane-based-surgical-anesthesia-determines-severity-of-brain-injury-and-neurological-deficits-after-a-transient-focal-ischemia-in-young-adult-rats
#4
Nikhil Gaidhani, Fen Sun, Derek Schreihofer, Victor V Uteshev
Tremendous efforts and funds invested in discovery of novel drug treatments for ischemic stroke have so far failed to deliver clinically efficacious therapies. The reasons for these failures are not fully understood. An indiscriminate use of isoflurane-based surgical anesthesia with or without nitrous oxide may act as an unconstrained, untraceable source of data variability, potentially causing false-positive or false-negative results. To test this hypothesis, a common transient suture middle cerebral artery occlusion (tMCAO) model of ischemic stroke in young adult male rats was used to determine the impact of a typical range of anesthesia durations required for this model on data variability (i...
July 27, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28736792/double-injected-human-stem-cells-enhance-rehabilitation-in-tbi-mice-via-modulation-of-survival-and-inflammation
#5
Chul Kim, Ji-Min Park, TaeHo Kong, Seungmin Lee, Ki-Weon Seo, Yuri Choi, Young Sook Song, Jisook Moon
Traumatic brain injury (TBI), a complicated form of brain damage, is a major cause of mortality in adults. Following mechanical and structural primary insults, a battery of secondary insults, including neurotransmitter-mediated cytotoxicity, dysregulation of calcium and macromolecule homeostasis, and increased oxidative stress, exacerbate brain injury and functional deficits. Although stem cell therapy is considered to be an alternative treatment for brain injuries, such as TBI and stroke, many obstacles remain...
July 24, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28732515/sexually-divergent-induction-of-microglial-associated-neuroinflammation-with-hippocampal-aging
#6
Colleen A Mangold, Benjamin Wronowski, Mei Du, Dustin R Masser, Niran Hadad, Georgina V Bixler, Robert M Brucklacher, Matthew M Ford, William E Sonntag, Willard M Freeman
BACKGROUND: The necessity of including both males and females in molecular neuroscience research is now well understood. However, there is relatively limited basic biological data on brain sex differences across the lifespan despite the differences in age-related neurological dysfunction and disease between males and females. METHODS: Whole genome gene expression of young (3 months), adult (12 months), and old (24 months) male and female C57BL6 mice hippocampus was analyzed...
July 21, 2017: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/28724035/spontaneous-carotid-dissection
#7
Carolina Dutra Queiroz Flumignan, Ronald Luiz Gomes Flumignan, Luis Carlos Uta Nakano, Jorge Eduardo de Amorim
Carotid dissection is a rare occurrence but it is the main cause of stroke in individuals aged less than 45 years, and can be the etiology in up to 25% of strokes in young adults. We report a case with classic image of ying yang on vascular ultrasound, which was treated according to the best available medical evidence, yielding a favorable outcome.
May 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28722518/effects-of-pentoxifylline-on-hemodynamic-hemorheological-and-microcirculatory-parameters-in-young-shrs-during-arterial-hypertension-development
#8
Mark B Plotnikov, Oleg I Aliev, Alexander Y Shamanaev, Anastasia V Sidekhmenova, Yana Anfinogenova, Anna M Anishchenko, Tatiana I Fomina, Alexander M Arkhipov
The most common form of hypertension in young adults is isolated diastolic hypertension. Diastolic arterial pressure is determined by the total peripheral resistance and depends on both vascular hindrance and blood viscosity. The aim of our work was to study the efficiency of pentoxifylline (PTX) in young spontaneously hypertensive rats (SHRs) during the development of arterial hypertension. The effects of a treatment course with PTX (100 mg/kg/day p.o. for 6 weeks, from 5 to 11 weeks old) on the mean, systolic, and diastolic blood pressure (BP); stroke volume; cardiac output; total peripheral resistance (TPR); whole blood viscosity (BV); plasma viscosity; hematocrit; RBC aggregation and deformability; local cerebral blood flow (lCBF); and microvascularization of the visual cortex were studied in SHRs in comparison with control SHRs and Wistar Kyoto rats...
July 19, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28715555/application-of-a-lifestyle-based-tool-to-estimate-premature-cardiovascular-disease-events-in-young-adults-the-coronary-artery-risk-development-in-young-adults-cardia-study
#9
Holly C Gooding, Hongyan Ning, Matthew W Gillman, Christina Shay, Norrina Allen, David C Goff, Donald Lloyd-Jones, Stephanie Chiuve
Importance: Few tools exist for assessing the risk for early atherosclerotic cardiovascular disease (ASCVD) events in young adults. Objective: To assess the performance of the Healthy Heart Score (HHS), a lifestyle-based tool that estimates ASCVD events in older adults, for ASCVD events occurring before 55 years of age. Design, Setting, and Participants: This prospective cohort study included 4893 US adults aged 18 to 30 years from the Coronary Artery Risk Development in Young Adults (CARDIA) study...
July 17, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28709742/age-and-gender-differences-in-the-association-between-serum-25-hydroxyvitamin-d-and-stroke-in-the-general-us-population-the-national-health-and-nutrition-examination-survey-2001-2006
#10
Ji Li, Hong Lai, Lifang Yang, Hong Zhu, Shaoguang Chen, Shenghan Lai
BACKGROUND: Previous findings on the association between serum 25(OH)D level and stroke have been controversial. We aimed to examine whether these controversial findings could be possibly due to difference in study participant characteristics, especially age and gender differences in these studies, by analyzing the data from a representative sample of the general US population. METHODS: Data of 13,642 adults 20 years or older who participated in the 2001-2006 National Health and Nutrition Examination Survey were analyzed in this study...
July 11, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28691203/previously-undiagnosed-risk-factors-and-medication-nonadherence-are-prevalent-in-young-adults-with-first-ever-stroke
#11
Sheng-Feng Sung, Edward Chia-Cheng Lai, Darren Philbert Wu, Cheng-Yang Hsieh
PURPOSE: The incidence of stroke and prevalence of traditional vascular risk factors (VRFs) in young adults (age < 55 y) are both increasing. Young patients tend to be unaware of their VRFs and to have lower medication adherence. We examined how age affects the prevalence of previously undiagnosed VRFs and the extent of medication nonadherence among stroke patients. METHODS: Using Taiwan's National Health Insurance Research Database, we identified consecutive adult patients with first-ever stroke between 2000 and 2013...
July 10, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28671997/post-stroke-angiotensin-ii-type-2-receptor-activation-provides-long-term-neuroprotection-in-aged-rats
#12
Douglas M Bennion, Jacob D Isenberg, Allison T Harmel, Kelly DeMars, Alex N Dang, Chad H Jones, Megan E Pignataro, Justin T Graham, U Muscha Steckelings, Jon C Alexander, Marcelo Febo, Eric G Krause, Annette D de Kloet, Eduardo Candelario-Jalil, Colin Sumners
Activation of the angiotensin II type 2 receptor (AT2R) by administration of Compound 21 (C21), a selective AT2R agonist, induces neuroprotection in models of ischemic stroke in young adult animals. The mechanisms of this neuroprotective action are varied, and may include direct and indirect effects of AT2R activation. Our objectives were to assess the long-term protective effects of post-stroke C21 treatments in a clinically-relevant model of stroke in aged rats and to characterize the cellular localization of AT2Rs in the mouse brain of transgenic reporter mice following stroke...
2017: PloS One
https://www.readbyqxmd.com/read/28670161/left-ventricular-functional-parameters-and-geometric-patterns-in-korean-adults-on-coronary-ct-angiography-with-a-320-detector-row-ct-scanner
#13
Eun-Ju Kang, Ki-Nam Lee, Won Jin Choi, Young-Dae Kim, Kyung Min Shin, Jae-Kwang Lim, Jongmin Lee
OBJECTIVE: To assess the normal reference values of left ventricle (LV) functional parameters in Korean adults on coronary CT angiography (CCTA) with a 320-detector-row CT scanner, and to analyze sex-related differences and correlations with various clinical characteristics. MATERIALS AND METHODS: This study retrospectively enrolled 172 subjects (107 men and 65 women; age, 58 ± 10.9 years; body surface area [BSA], 1.75 ± 0.2 m(2)) who underwent CCTA without any prior history of cardiac disease...
July 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28660849/racial-differences-in-neurocognitive-outcomes-post-stroke-the-impact-of-healthcare-variables
#14
Neco X Johnson, Maria J Marquine, Ilse Flores, Anya Umlauf, Carolyn M Baum, Alex W K Wong, Alexis C Young, Jennifer J Manly, Allen W Heinemann, Susan Magasi, Robert K Heaton
OBJECTIVES: The present study examined differences in neurocognitive outcomes among non-Hispanic Black and White stroke survivors using the NIH Toolbox-Cognition Battery (NIHTB-CB), and investigated the roles of healthcare variables in explaining racial differences in neurocognitive outcomes post-stroke. METHODS: One-hundred seventy adults (91 Black; 79 White), who participated in a multisite study were included (age: M=56.4; SD=12.6; education: M=13.7; SD=2.5; 50% male; years post-stroke: 1-18; stroke type: 72% ischemic, 28% hemorrhagic)...
June 29, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28659214/the-risk-of-stroke-after-prenatal-exposure-to-famine
#15
J Horenblas, S R de Rooij, T J Roseboom
Prenatal exposure to famine is associated with an increased risk of metabolic and cardiovascular diseases in the offspring at adult age. The aim of this study was to assess whether prenatal exposure to undernutrition increases the risk of stroke. This study was performed in the Dutch famine birth cohort, which consist of 2414 members who were born between 1943 and 1947 in the Netherlands. In a subsample of 1177 individuals, interviews were conducted using standardized questionnaires to obtain information about medical history (which included specific questions regarding stroke) and lifestyle...
June 29, 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/28657357/ecg-markers-associated-with-ischemic-stroke-at-young-age-a-case-control-study
#16
Jani Pirinen, Antti Eranti, Paul Knekt, Mika Lehto, Nicolas Martinez-Majander, Aapo L Aro, Harri Rissanen, Markku Heliövaara, Markku Kaste, Turgut Tatlisumak, Heikki Huikuri, Jukka Putaala
INTRODUCTION: Certain electrocardiographic (ECG) abnormalities are associated with ischemic stroke (IS), especially cardioembolic subtype. Besides atrial fibrillation, markers of left ventricular hypertrophy (LVH) or atrial pathology also reflect elevated risk. We studied the association of ECG markers with IS in young adults. METHODS: We performed a case-control study including 567 consecutive IS patients aged 15-49 years (inclusion period: 1994-2007) and one or two age- and sex-matched control subjects enrolled during 1978-1980 (n = 1033), and investigated also the stroke aetiologic subgroups...
July 14, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/28646558/neurology-concepts-young-women-and-ischemic-stroke-evaluation-and-management-in-the-emergency-department
#17
Bernard P Chang, Charles Wira, Joseph Miller, Murtaza Akhter, Bradley E Barth, Joshua Willey, Lauren Nentwich, Tracy Madsen
OBJECTIVE: Ischemic stroke is a leading cause of morbidity and mortality worldwide. While the incidence of ischemic stroke is highest in older populations, incidence of ischemic stroke in adults has been rising particularly rapidly among young (e.g. premenopausal) women. The evaluation and timely diagnosis of ischemic stroke in young women presents a challenging situation in the emergency department, due to a range of sex-specific risk factors and to broad differentials. The goals of this concepts paper are to summarize existing knowledge regarding the evaluation and management of young women with ischemic stroke in the acute setting...
June 24, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28644921/targeted-memory-reactivation-during-sleep-but-not-wake-enhances-sensorimotor-skill-performance-a-pilot-study
#18
Brian P Johnson, Steven M Scharf, Kelly P Westlake
The benefits of sleep on memory consolidation have been enhanced for declarative and motor sequence learning through replaying classically conditioned auditory stimuli during sleep, known as targeted memory reactivation (TMR). However, it is unknown if TMR can influence performance of a sensorimotor skill, in the absence of the cognitive requirements of sequence learning. Here, young adults performed a nondominant arm throwing task separated by a full night of sleep or a full day of wake, with half of all participants receiving TMR between sessions...
June 23, 2017: Journal of Motor Behavior
https://www.readbyqxmd.com/read/28642352/management-of-brain-arteriovenous-malformations-a-scientific-statement-for-healthcare-professionals-from-the-american-heart-association-american-stroke-association
#19
REVIEW
Colin P Derdeyn, Gregory J Zipfel, Felipe C Albuquerque, Daniel L Cooke, Edward Feldmann, Jason P Sheehan, James C Torner
PURPOSE: The aim of this statement is to review the current data and to make suggestions for the diagnosis and management of both ruptured and unruptured brain arteriovenous malformations. METHODS: The writing group met in person and by teleconference to establish search terms and to discuss narrative text and suggestions. Authors performed their own literature searches of PubMed, Medline, or Embase, specific to their allocated section, through the end of January 2015...
August 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28626830/overweight-obesity-and-risk-of-cardiometabolic-multimorbidity-pooled-analysis-of-individual-level-data-for-120%C3%A2-813-adults-from-16-cohort-studies-from-the-usa-and-europe
#20
Mika Kivimäki, Eeva Kuosma, Jane E Ferrie, Ritva Luukkonen, Solja T Nyberg, Lars Alfredsson, G David Batty, Eric J Brunner, Eleonor Fransson, Marcel Goldberg, Anders Knutsson, Markku Koskenvuo, Maria Nordin, Tuula Oksanen, Jaana Pentti, Reiner Rugulies, Martin J Shipley, Archana Singh-Manoux, Andrew Steptoe, Sakari B Suominen, Töres Theorell, Jussi Vahtera, Marianna Virtanen, Peter Westerholm, Hugo Westerlund, Marie Zins, Mark Hamer, Joshua A Bell, Adam G Tabak, Markus Jokela
BACKGROUND: Although overweight and obesity have been studied in relation to individual cardiometabolic diseases, their association with risk of cardiometabolic multimorbidity is poorly understood. Here we aimed to establish the risk of incident cardiometabolic multimorbidity (ie, at least two from: type 2 diabetes, coronary heart disease, and stroke) in adults who are overweight and obese compared with those who are a healthy weight. METHODS: We pooled individual-participant data for BMI and incident cardiometabolic multimorbidity from 16 prospective cohort studies from the USA and Europe...
June 2017: Lancet. Public Health
keyword
keyword
11842
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"