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European Journal of Pain

David J Keene, Dipesh Mistry, Julian Nam, Elizabeth Tutton, Robert Handley, Lesley Morgan, Emma Roberts, Bridget Gray, Andrew Briggs, Ranjit Lall, Tim Js Chesser, Ian Pallister, Sarah E Lamb, Keith Willett
BACKGROUND: Close contact casting (CCC) may offer an alternative to open reduction and internal fixation (ORIF) surgery for unstable ankle fractures in older adults. OBJECTIVES: We aimed to (1) determine if CCC for unstable ankle fractures in adults aged over 60 years resulted in equivalent clinical outcome compared with ORIF, (2) estimate cost-effectiveness to the NHS and society and (3) explore participant experiences. DESIGN: A pragmatic, multicentre, equivalence randomised controlled trial incorporating health economic evaluation and qualitative study...
October 2016: Health Technology Assessment: HTA
Biswanath Dinda, Anthony M Kyriakopoulos, Subhajit Dinda, Vassilis Zoumpourlis, Nikolaos S Thomaidis, Aristea Velegraki, Charlambos Markopoulos, Manikarna Dinda
ETHNOPHARMACOLOGICAL RELEVANCE: Cornus mas L. (cornelian cherry) fruits have been used for centuries as traditional cuisine and folk medicine in various countries of Europe and Asia. In folk medicines, the fruits and other parts of the plant have been used for prevention and treatment of a wide range of diseases such as diabetes, diarrhea, gastrointestinal disorders, fevers, rheumatic pain, skin and urinary tract infections, kidney and liver diseases, sunstroke, among others. This review provides a systematic and constructive overview of ethnomedicinal uses, chemical constituents and pharmacological activities of this plant as well as future research need for its commercial utilization as nutraceutical food supplement and medicine...
October 2, 2016: Journal of Ethnopharmacology
Giustino Varrassi, Antonella Paladini
Professor Giustino Varrassi and Antonella Paladini speak to Jade Parker, Commissioning Editor: Professor Giustino Varrassi is Full Professor of Anesthesiology and Pain Medicine in the LUdeS University, Valletta, Malta. He graduated at the Medical School of the University 'La Sapienza' (Rome, Italy) in 1973, and became board certified in Anesthesiology and Intensive Care in 1976 and in Pneumology in 1978, both in the same Medical School. He is currently President of the European League Against Pain and of the Paolo Procacci Foundation, and is a founding member of both of these...
September 19, 2016: Pain Management
Yolana Pringle
This article uses a case-study approach to examine the complex and contradictory nature of diagnoses like neurasthenia in colonial Africa. Drawing on the case notes of European and African patients diagnosed with neurasthenia at the Church Missionary Society's Mengo Hospital, Uganda, it argues that in practice, and outside the colonial asylum in particular, ideas about race and mental illness were more nuanced than histories of psychiatry and empire might imply. At Mengo, the tales of pain and suffering recorded by the doctors remind us that there is more to the history of neurasthenia than colonial anxieties and socio-political control...
March 3, 2016: Journal of Imperial and Commonwealth History
P J Allan, P Stevens, A Abraham, P Paine, K Farrer, A Teubner, G Carlson, S Lal
BACKGROUND/OBJECTIVES: Bariatric surgery for morbid obesity provides sustained weight loss. Complications of bariatric surgery include severe nutritional decline, but minimal data describing occurrence and outcome of intestinal failure (IF) exist. SUBJECTS/METHODS: All patients referred to one of the UK's National IF units (IFU) are prospectively entered onto a database; case notes were assessed for bariatric surgery details, IF onset, outcomes, resulting intestinal anatomy, mortality and catheter-related bloodstream infections (CRBSIs)...
July 2016: European Journal of Clinical Nutrition
Haruki Ueda, Holt S Cutler, Javier Z Guzman, Samuel K Cho
Study Design Bibliometric analysis. Objective To determine trends, frequency, and distribution of patient-reported outcome instruments (PROIs) in degenerative cervical spine surgery literature over the past decade. Methods A search was conducted via PubMed from 2004 to 2013 on five journals (The Journal of Bone and Joint Surgery, The Bone and Joint Journal, The Spine Journal, European Spine Journal, and Spine), which were chosen based on their impact factors and authors' consensus. All abstracts were screened and articles addressing degenerative cervical spine surgery using PROIs were included...
May 2016: Global Spine Journal
(no author information available yet)
The above article from European Journal of Neuroscience, published online on 4 February 2014 in Wiley Online Library (, has been retracted by agreement between the Editors-in-Chief, Paul Bolam and John Foxe, the authors and John Wiley & Sons Ltd. The retraction has been agreed as the above article has been found to overlap substantially with the article 'Chiou, L.-C., Hu, S. S.-J., and Ho, Y.-C. (2013), Targeting the cannabinoid system for pain relief? Acta Anaesthesiologica Taiwanica, Volume 51, Issue 4: 161 - 170...
April 2016: European Journal of Neuroscience
Jordan D Dworkin, Andrew McKeown, John T Farrar, Ian Gilron, Matthew Hunsinger, Robert D Kerns, Michael P McDermott, Bob A Rappaport, Dennis C Turk, Robert H Dworkin, Jennifer S Gewandter
OBJECTIVE: The goal of this study was to assess the quality of reporting of statistical methods in randomized clinical trials (RCTs), including identification of primary analyses, missing data accommodation, and multiplicity adjustment, in studies of nonpharmacologic, noninterventional pain treatments (e.g., physical therapy, cognitive behavioral therapy, acupuncture, and massage). STUDY DESIGN: Systematic review of 101 articles reporting RCTs of pain treatments that were published between January 2006 and June 2013 in the European Journal of Pain, the Journal of Pain, and Pain...
April 2016: Journal of Clinical Epidemiology
Robert Pickard, Kathryn Starr, Graeme MacLennan, Mary Kilonzo, Thomas Lam, Ruth Thomas, Jennifer Burr, John Norrie, Gladys McPherson, Alison McDonald, Kirsty Shearer, Katie Gillies, Kenneth Anson, Charles Boachie, James N'Dow, Neil Burgess, Terry Clark, Sarah Cameron, Samuel McClinton
BACKGROUND: Ureteric colic, the term used to describe the pain felt when a stone passes down the ureter from the kidney to the bladder, is a frequent reason for people to seek emergency health care. Treatment with the muscle-relaxant drugs tamsulosin hydrochloride (Petyme, TEVA UK Ltd) and nifedipine (Coracten(®), UCB Pharma Ltd) as medical expulsive therapy (MET) is increasingly being used to improve the likelihood of spontaneous stone passage and lessen the need for interventional procedures...
August 2015: Health Technology Assessment: HTA
Janneke G Langendonk, Manisha Balwani, Karl E Anderson, Herbert L Bonkovsky, Alexander V Anstey, D Montgomery Bissell, Joseph Bloomer, Chris Edwards, Norbert J Neumann, Charles Parker, John D Phillips, Henry W Lim, Iltefat Hamzavi, Jean-Charles Deybach, Raili Kauppinen, Lesley E Rhodes, Jorge Frank, Gillian M Murphy, Francois P J Karstens, Eric J G Sijbrands, Felix W M de Rooij, Mark Lebwohl, Hetanshi Naik, Colin R Goding, J H Paul Wilson, Robert J Desnick
BACKGROUND: Erythropoietic protoporphyria is a severe photodermatosis that is associated with acute phototoxicity. Patients with this condition have excruciating pain and a markedly reduced quality of life. We evaluated the safety and efficacy of an α-melanocyte-stimulating hormone analogue, afamelanotide, to decrease pain and improve quality of life. METHODS: We conducted two multicenter, randomized, double-blind, placebo-controlled trials of subcutaneous implants containing 16 mg of afamelanotide...
July 2, 2015: New England Journal of Medicine
Mia Schmidt-Hansen, Nathan Bromham, Mark Taubert, Stephanie Arnold, Jennifer S Hilgart
BACKGROUND: Many patients with cancer experience moderate to severe pain that requires treatment with strong analgesics. Buprenorphine, fentanyl and morphine are examples of strong opioids used for cancer pain relief. However, strong opioids are ineffective as pain treatment in all patients and are not well-tolerated by all patients. The aim of this Cochrane review is to assess whether buprenorphine is associated with superior, inferior or equal pain relief and tolerability compared to other analgesic options for patients with cancer pain...
2015: Cochrane Database of Systematic Reviews
Shannon M Smith, Matthew Hunsinger, Andrew McKeown, Melissa Parkhurst, Robert Allen, Stephen Kopko, Yun Lu, Hilary D Wilson, Laurie B Burke, Paul Desjardins, Michael P McDermott, Bob A Rappaport, Dennis C Turk, Robert H Dworkin
UNLABELLED: Pain intensity assessments are used widely in human pain research, and their transparent reporting is crucial to interpreting study results. In this systematic review, we examined reporting of human pain intensity assessments and related elements (eg, administration frequency, time period assessed, type of pain) in all empirical pain studies with adult participants in 3 major pain journals (ie, European Journal of Pain, Journal of Pain, and Pain) between January 2011 and July 2012...
April 2015: Journal of Pain: Official Journal of the American Pain Society
Sheena Derry, Philip J Wiffen, Dominic Aldington, R Andrew Moore
BACKGROUND: Antidepressants are widely used to treat chronic neuropathic pain (pain due to nerve damage), usually in doses below those at which they exert antidepressant effects. An earlier review that included all antidepressants for neuropathic pain is being replaced by new reviews of individual drugs examining individual neuropathic pain conditions.Nortriptyline is a tricyclic antidepressant that is occasionally used for treating neuropathic pain, and is recommended in European, UK, and USA guidelines...
2015: Cochrane Database of Systematic Reviews
Robert C Mulholland
This is a review of some 50 papers published in the European Spine Journal in the year 2014. They are selected on the basis that the author felt they were significant contributions to the spinal literature in that year. A brief precis is provided of each paper, and each is accompanied by a short discussion explaining its importance and relevance.
January 2015: European Spine Journal
Andrew McKeown, Jennifer S Gewandter, Michael P McDermott, Joseph R Pawlowski, Joseph J Poli, Daniel Rothstein, John T Farrar, Ian Gilron, Nathaniel P Katz, Allison H Lin, Bob A Rappaport, Michael C Rowbotham, Dennis C Turk, Robert H Dworkin, Shannon M Smith
UNLABELLED: Sample size calculations determine the number of participants required to have sufficiently high power to detect a given treatment effect. In this review, we examined the reporting quality of sample size calculations in 172 publications of double-blind randomized controlled trials of noninvasive pharmacologic or interventional (ie, invasive) pain treatments published in European Journal of Pain, Journal of Pain, and Pain from January 2006 through June 2013. Sixty-five percent of publications reported a sample size calculation but only 38% provided all elements required to replicate the calculated sample size...
March 2015: Journal of Pain: Official Journal of the American Pain Society
Michel Benoist
No abstract text is available yet for this article.
January 2015: European Spine Journal
Nils H Münter, Ana Stevanovic, Rolf Rossaint, Christian Stoppe, Robert D Sanders, Mark Coburn
BACKGROUND: Randomised controlled trials (RCTs) are the gold standard for measuring the efficacy of any medical intervention. The present study assesses the implementation of the CONSORT statement in the top 11 anaesthesiology journals in 2011. OBJECTIVES: We designed this study in order to determine how well authors in the top 11 ranked anaesthesiology journals follow the CONSORT statement's criteria. DESIGN: A retrospective cross-sectional data analysis...
February 2015: European Journal of Anaesthesiology
(no author information available yet)
Ping Gao, Shun-Chang Jiao, Li Bai, et al. 'Detection of circulating tumour cells in gastric and hepatocellular carcinoma: A systematic review' Journal of International Medical Research August 2013 vol. 41 no. 4 923-933. DOI: 10.1177/0300060513489789 has been retracted. This is because it contains unattributed overlap with material from the following article: FC Bidard, FR Ferrand, F Huguet, et al. 'Disseminated and circulating tumor cells in gastrointestinal oncology' Critical Reviews in Oncology / Hematology, Volume 82, Issue 2, Pages 103-115, May 2012...
October 2014: Journal of International Medical Research
Christine B Davis, Richard M Nowak
This is a case of nontraumatic shoulder pain initially diagnosed on x-ray as an anterior dislocation. The patient was on anticoagulants and, in actuality, had severe hemarthrosis that caused the subluxation. Attempts to reduce the dislocation in this situation might have resulted in worsening of the intra-articular bleed. There has been only 1 similar reported case in the European Journal of Emergency Medicine in 2013 of a 53-year-old woman who was thought to have a nontraumatic anterior shoulder dislocation, and attempts were unsuccessful at reduction...
December 2014: American Journal of Emergency Medicine
Jennifer S Gewandter, Michael P McDermott, Andrew McKeown, Shannon M Smith, Mark R Williams, Matthew Hunsinger, John Farrar, Dennis C Turk, Robert H Dworkin
Missing data in clinical trials can bias estimates of treatment effects. Statisticians and government agencies recommend making every effort to minimize missing data. Although statistical methods are available to accommodate missing data, their validity depends on often untestable assumptions about why the data are missing. The objective of this study was to assess the frequency with which randomized clinical trials published in 3 major pain journals (ie, European Journal of Pain, Journal of Pain, and Pain) reported strategies to prevent missing data, the number of participants who completed the study (ie, completers), and statistical methods to accommodate missing data...
September 2014: Pain
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