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Pediatric febrile seizures

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https://www.readbyqxmd.com/read/28157600/development-and-validation-of-aiims-modified-inclen-diagnostic-instrument-for-epilepsy-in-children-aged-1-month-18-years
#1
Sheffali Gulati, Harsh Patel, Biswaroop Chakrabarty, Rachana Dubey, N K Arora, R M Pandey, V K Paul, Konanki Ramesh, Vyshakh Anand, Ankit Meena
OBJECTIVES: There is shortage of specialists for the diagnosis of children with epilepsy, especially in resource limited settings. Existing INCLEN (International Clinical Epidemiology Network) instrument was validated for children aged 2-9 years. The current study validated modifications of the same including wider symptomatology and age group. METHODS: The Modified INCLEN tool was validated by a team of experts by modifying the existing tools (2-9 years) to widen the age range from 1 month to 18 years and include broader symptomatology in a tertiary care teaching hospital of North India between January and June 2015...
January 25, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28121976/variation-in-pediatric-care-between-academic-and-nonacademic-us-emergency-departments-1995-2010
#2
Joyce Li, Michael C Monuteaux, Richard G Bachur
OBJECTIVES: The aim of this study was to describe the resource utilization for children with common pediatric conditions treated in academic and nonacademic emergency departments (EDs). METHODS: We performed a retrospective, cross-sectional descriptive study using the National Hospital Ambulatory Medical Care Survey Data from 1995 to 2010 including children less than 18 years old with a diagnosis of asthma, bronchiolitis, croup, gastroenteritis, fever, febrile seizure, or afebrile seizure...
January 24, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28078877/congenital-muscular-dystrophy-and-epilepsy-a-prospective-case-series-of-pediatric-patients
#3
G Vitaliti, P Pavone, C Romano, M Barbagallo, M Vecchio, C Ledda, R Lubrano, R Falsaperla
Congenital Muscular Dystrophies (CMDs) can be considered as a heterogeneous group of diseases characterized by marked weakness, generalized hypotonia and joint contractures. They are divided into pure and classical forms, without ocular and cerebral involvement, and complex forms, which are associated with cerebral abnormalities. Seizures have rarely been described in the pure forms while they seem to occur more frequently in complex forms. The aim of our study was to evaluate the incidence of seizure in CMD...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28018466/a-young-child-of-anti-nmda-receptor-encephalitis-presenting-with-epilepsia-partialis-continua-the-first-pediatric-case-in-korea
#4
Eun-Hee Kim, Yeo Jin Kim, Tae-Sung Ko, Mi-Sun Yum, Jun Hwa Lee
Anti-N-methyl D-aspartate receptor (anti-NMDAR) encephalitis, recently recognized as a form of paraneoplastic encephalitis, is characterized by a prodromal phase of unspecific illness with fever that resembles a viral disease. The prodromal phase is followed by seizures, disturbed consciousness, psychiatric features, prominent abnormal movements, and autonomic imbalance. Here, we report a case of anti-NMDAR encephalitis with initial symptoms of epilepsia partialis continua in the absence of tumor. Briefly, a 3-year-old girl was admitted to the hospital due to right-sided, complex partial seizures without preceding febrile illness...
November 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/28018437/1p36-deletion-syndrome-confirmed-by-fluorescence-in-situ-hybridization-and-array-comparative-genomic-hybridization-analysis
#5
Dong Soo Kang, Eunsim Shin, Jeesuk Yu
Pediatric epilepsy can be caused by various conditions, including specific syndromes. 1p36 deletion syndrome is reported in 1 in 5,000-10,000 newborns, and its characteristic clinical features include developmental delay, mental retardation, hypotonia, congenital heart defects, seizure, and facial dysmorphism. However, detection of the terminal deletion in chromosome 1p by conventional G-banded karyotyping is difficult. Here we present a case of epilepsy with profound developmental delay and characteristic phenotypes...
November 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/27930967/epidemiology-and-diagnostic-and-therapeutic-management-of-febrile-seizures-in-the-italian-pediatric-emergency-departments-a-prospective-observational-study
#6
Giovanna Vitaliti, Emanuele Castagno, Fulvio Ricceri, Antonio Urbino, Alberto Verrotti Di Pianella, Riccardo Lubrano, Elisa Caramaschi, Maurizio Prota, Rita Maria Pulvirenti, Patrizia Ajovalasit, Giuseppe Signorile, Carla Navone, Maria Rosaria La Bianca, Alberto Villani, Giovanni Corsello, Raffaele Falsaperla
AIM: Febrile seizures (FS) involve 2-5% of the paediatric population, among which Complex FS (CFS) account for one third of accesses for FS in Emergency Departments (EDs). The aim of our study was to define the epidemiology, the clinical, diagnostic and therapeutic approach to FS and CFSs in the Italian EDs. METHODS: A multicenter prospective observational study was performed between April 2014 and March 2015. Patients between 1 and 60 months of age, randomly accessing to ED for ongoing FS or reported FS at home were included...
January 2017: Epilepsy Research
https://www.readbyqxmd.com/read/27843467/comparison-of-relation-between-attention-deficit-hyperactivity-disorder-in-children-with-and-without-simple-febrile-seizure-admitted-in-arak-central-iran
#7
Bahman Salehi, Parsa Yousefichaijan, Smira Safi Arian, Somaieh Ebrahimi, Mahdyieh Naziri
OBJECTIVE: Febrile seizure is one of the most prevalent childhood convulsions with the most common age of onset at 14-18 mo old. Fever decreases the brain threshold for seizure. Attention Deficit Hyperactivity Disorder (ADHD) is also a neurologic-behavioral problem defined by attention deficit and hyperactivity according to DSM-IV criteria in which the child must have these signs in two different environments. There is controversy on the possible relation between febrile seizure and ADHD; while some studies approve a strong relation, some exclude any relation and some attribute ADHD to the side effects of other reasons...
2016: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/27833858/neurogenic-pulmonary-edema-combined-with-febrile-seizures-in-early-childhood-a-report-of-two-cases
#8
Keiji Tasaka, Kousaku Matsubara, Masayuki Hori, Hiroyuki Nigami, Aya Iwata, Kenichi Isome, Yu Kawasaki, Sadayuki Nagai
Neurogenic pulmonary edema (NPE) is a clinical entity that can occur following central nervous system disorders. However, NPE occurs quite rarely in early childhood, and there has only been one report about pediatric NPE associated with febrile seizures. Two cases are reported here. One case involved a 2-year-old girl who presented with febrile seizures, which rapidly progressed to severe NPE. Since the NPE occurred in the emergency department room, the patient was able to be resuscitated via immediate endotracheal intubation...
2016: IDCases
https://www.readbyqxmd.com/read/27784471/-expert-consensus-on-the-diagnosis-and-management-of-febrile-seizures-2016
#9
(no author information available yet)
No abstract text is available yet for this article.
October 2, 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27773903/efficacy-of-potassium-bromide-in-the-treatment-of-drug-resistant-epilepsy-a-case-of-new-onset-refractory-status-epilepticus
#10
Jun Takei, Ran Takei, Satoshi Nozuma, Keiichi Nakahara, Osamu Watanabe, Hiroshi Takashima
A 40-year-old man presented with a series of generalized tonic-clonic seizures after febrile illness. He developed status epilepticus and required mechanical ventilation with anesthetics. Steroid pulse, intravenous immunoglobulin, and immunoadsorption therapy were administrated, and the status epilepticus improved; however, drug-resistant seizures remained. Despite the use of several antiepileptic drugs, seizures frequently occurred. Additional administration of potassium bromide resulted in significant suppression of seizures...
November 29, 2016: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/27612489/hippocampal-formation-maldevelopment-and-sudden-unexpected-death-across-the-pediatric-age-spectrum
#11
Hannah C Kinney, Annapurna H Poduri, Jane B Cryan, Robin L Haynes, Lisa Teot, Lynn A Sleeper, Ingrid A Holm, Gerald T Berry, Sanjay P Prabhu, Simon K Warfield, Catherine Brownstein, Harry S Abram, Michael Kruer, Walter L Kemp, Beata Hargitai, Joanne Gastrang, Othon J Mena, Elisabeth A Haas, Roya Dastjerdi, Dawna D Armstrong, Richard D Goldstein
Sudden infant death syndrome (SIDS) and sudden unexplained death in childhood (SUDC) are defined as sudden death in a child remaining unexplained despite autopsy and death scene investigation. They are distinguished from each other by age criteria, i.e. with SIDS under 1 year and SUDC over 1 year. Our separate studies of SIDS and SUDC provide evidence of shared hippocampal abnormalities, specifically focal dentate bilamination, a lesion classically associated with temporal lobe epilepsy, across the 2 groups...
September 9, 2016: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/27467370/the-association-between-plasma-ferritin-level-and-simple-febrile-seizures-in-children
#12
Ali O Köksal, Osman Özdemir, Bahar Büyükkaragöz, Merve Karaömerlioglu, Ayse D Bulus
INTRODUCTION: We conducted this study to determine the role of iron deficiency (ID) as a risk factor for simple febrile seizure (SFS) in 6- to 60-month-old children. MATERIALS AND METHODS: In this case-control study 100 children aged 6 to 60 months with febrile seizure (FS) (study group) and 100 febrile children without seizures (control group) admitted to Pediatric Departments of Kecioren Training and Research Hospital in between June 2014 and March 2015 were evaluated...
October 2016: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/27434885/effectiveness-of-electroconvulsive-therapy-for-refractory-status-epilepticus-in-febrile-infection-related-epilepsy-syndrome
#13
Alicia Mirás Veiga, David Conejo Moreno, Ana Isabel Gómez Menéndez, Ignacio Muñoz Siscart, Marta Del Olmo Fernández, Esteban Gómez Sánchez, María García González, Fernando Gómez Sáez
Febrile infection-related epilepsy syndrome (FIRES) is a rare condition which evolves into refractory status epilepticus (SE), with poor outcome in most cases. Conventional antiepileptic drugs fail to control SE in FIRES patients. We report the case of a previously healthy 4-year-old boy who was diagnosed with FIRES. One week after pharyngitis and high fever he started seizures, followed by refractory SE. Benzodiazepines, phenytoin, high-dose barbiturates that induce burst suppression, high doses of corticosteroids, plasmapheresis, immunoglobulins, propofol, lidocaine, ketamine, inhaled desflurane, ketogenic diet, lacosamide, and therapeutic hypothermia were tried at different times in a period of 8 weeks, but all of them were ineffective...
February 2017: Neuropediatrics
https://www.readbyqxmd.com/read/27375752/neurological-manifestations-of-renal-diseases-in-children-in-qazvin-iran
#14
Reza Dalirani, Abolfazl Mahyar, Parviz Ayazi, Ghazaleh Ahmadi
OBJECTIVE: Renal diseases are one of the most common causes of referrals and admissions of children, hence it is important to know their neurological presentations. This study aimed to determine neurological presentations of renal diseases in children. MATERIAL & METHODS: A total of 634 children with renal diseases, admitted to Qazvin Pediatric Hospital, Qazvin, central Iran from 2011 to 2013 were studied. Neurological presentations of patients were established and the results were analyzed using statistical tests...
2016: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/27349086/-abnormal-cerebral-blood-flow-distributions-during-the-post-ictal-phase-of-febrile-status-epilepticus-in-three-pediatric-patients-measured-by-arterial-spin-labeling-perfusion-mri
#15
Keiko Hirano, Tokiko Fukuda
The ability to visualize brain perfusion is important for identifying epileptic foci. We present three pediatric cases showing asymmetrical cerebral blood flow (CBF) distributions during the post-ictal phase of febrile status epilepticus measured by arterial spin labeling (ASL) perfusion MRI. During the acute phase, regional CBF measurements in the areas considered including epileptic foci were higher than in the corresponding area of the contralateral hemisphere, though the exact quantitative value varied between cases...
May 2016: No to Hattatsu. Brain and Development
https://www.readbyqxmd.com/read/27280723/epidemiology-of-pediatric-convulsive-status-epilepticus-with-fever-in-the-emergency-department-a-cohort-study-of-381-consecutive-cases
#16
Itaru Hayakawa, Sahoko Miyama, Nobuaki Inoue, Hiroshi Sakakibara, Hiroshi Hataya, Toshiro Terakawa
Pediatric convulsive status epilepticus with fever is common in the emergency setting but leads to severe neurological sequelae in some patients. To explore the epidemiology of convulsive status epilepticus with fever, a retrospective cohort covering all convulsive status epilepticus cases with fever seen in the emergency department of a tertiary care children's hospital were consecutively collected. Of the 381 consecutive cases gathered, 81.6% were due to prolonged febrile seizure, 6.6% to encephalopathy/encephalitis, 0...
September 2016: Journal of Child Neurology
https://www.readbyqxmd.com/read/27217077/prevalence-of-unique-pediatric-pathologies-encountered-by-paramedic-students-across-age-groups
#17
Eric V Ernest, Tom B Brazelton, Elliot D Carhart, Jonathan R Studnek, Patricia L Tritt, Genghis A Philip, Aaron M Burnett
UNLABELLED: Introduction Traditionally, Emergency Medical Services (EMS) educators have divided the pediatric population into age groups to assist in targeting their clinical and didactic curriculum. Currently, the accrediting body for paramedic training programs requires student exposure to pediatric patients based entirely on age without specifying exposure to specific pathologies within each age stratification. Identifying which pathologies are most common within the different pediatric age groups would allow educators to design curriculum targeting the most prevalent pathologies in each age group and incorporating the physiologic and psychological developmental milestones commonly seen at that age...
August 2016: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/27086496/la-crosse-encephalitis-an-adult-case-series
#18
Amy Lynn A Teleron, Brandon K Rose, David M Williams, Suzanne E Kemper, James E McJunkin
BACKGROUND: La Crosse viral encephalitis is well described in children, but to date, there are only 2 adult cases described in the literature. Despite the fact that pediatric infection can be life threatening and typically presents as a febrile meningoencephalitis often complicated by seizures and mental status changes, little is known about the presentation and course of adult infection. We report the largest case series of adult La Crosse encephalitis. METHODS: Inpatient data were reviewed between 2001 and 2012 to identify adults (≥18 years of age) with possible La Crosse encephalitis...
August 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/27057183/intermittent-diazepam-versus-continuous-phenobarbital-to-prevent-recurrence-of-febrile-seizures-a-randomized-controlled-trial
#19
Mohammadreza Salehiomran, Seyed Mohammad Hoseini, Ali Ghabeli Juibary
OBJECTIVE: Febrile seizure is the most common neurologic problem in children between 3 months to 5 years old. Two to five percent of children aged less than five yr old will experience it at least one time. This type of seizure is age dependent and its recurrence rate is about 33% overalls and 50% in children less than one yr old. The prophylactic treatment is still controversial, so we conducted a randomized controlled clinical trial to find out the effectiveness of continuous phenobarbital versus intermittent diazepam for febrile seizure...
2016: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/26986117/observational-study-of-a-french-and-belgian-multicenter-cohort-of-23-patients-diagnosed-in-adulthood-with-mevalonate-kinase-deficiency
#20
MULTICENTER STUDY
Cécile-Audrey Durel, Achille Aouba, Boris Bienvenu, Samuel Deshayes, Brigitte Coppéré, Bruno Gombert, Cécile Acquaviva-Bourdain, Eric Hachulla, Frédéric Lecomte, Isabelle Touitou, Jacques Ninet, Jean-Baptiste Philit, Laurent Messer, Marc Brouillard, Marie-Hélène Girard-Madoux, Michel Moutschen, Nadia Raison-Peyron, Pascal Hutin, Pierre Duffau, Pierre Trolliet, Pierre-Yves Hatron, Philippe Heudier, Ramiro Cevallos, Thierry Lequerré, Valentine Brousse, Vincent Lesire, Sylvain Audia, Delphine Maucort-Boulch, Laurence Cuisset, Arnaud Hot
The aim of this study was to describe the clinical and biological features of Mevalonate kinase deficiency (MKD) in patients diagnosed in adulthood. This is a French and Belgian observational retrospective study from 2000 to 2014. To constitute the cohort, we cross-check the genetic and biochemical databases. The clinical, enzymatic, and genetic data were gathered from medical records. Twenty-three patients were analyzed. The mean age at diagnosis was 40 years, with a mean age at onset of symptoms of 3 years...
March 2016: Medicine (Baltimore)
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