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Pediatric febrile seizures

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https://www.readbyqxmd.com/read/27843467/comparison-of-relation-between-attention-deficit-hyperactivity-disorder-in-children-with-and-without-simple-febrile-seizure-admitted-in-arak-central-iran
#1
Bahman Salehi, Parsa Yousefichaijan, Smira Safi Arian, Somaieh Ebrahimi, Mahdyieh Naziri
OBJECTIVE: Febrile seizure is one of the most prevalent childhood convulsions with the most common age of onset at 14-18 mo old. Fever decreases the brain threshold for seizure. Attention Deficit Hyperactivity Disorder (ADHD) is also a neurologic-behavioral problem defined by attention deficit and hyperactivity according to DSM-IV criteria in which the child must have these signs in two different environments. There is controversy on the possible relation between febrile seizure and ADHD; while some studies approve a strong relation, some exclude any relation and some attribute ADHD to the side effects of other reasons...
2016: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/27833858/neurogenic-pulmonary-edema-combined-with-febrile-seizures-in-early-childhood-a-report-of-two-cases
#2
Keiji Tasaka, Kousaku Matsubara, Masayuki Hori, Hiroyuki Nigami, Aya Iwata, Kenichi Isome, Yu Kawasaki, Sadayuki Nagai
Neurogenic pulmonary edema (NPE) is a clinical entity that can occur following central nervous system disorders. However, NPE occurs quite rarely in early childhood, and there has only been one report about pediatric NPE associated with febrile seizures. Two cases are reported here. One case involved a 2-year-old girl who presented with febrile seizures, which rapidly progressed to severe NPE. Since the NPE occurred in the emergency department room, the patient was able to be resuscitated via immediate endotracheal intubation...
2016: IDCases
https://www.readbyqxmd.com/read/27784471/-expert-consensus-on-the-diagnosis-and-management-of-febrile-seizures-2016
#3
(no author information available yet)
No abstract text is available yet for this article.
October 2, 2016: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/27773903/efficacy-of-potassium-bromide-in-the-treatment-of-drug-resistant-epilepsy-a-case-of-new-onset-refractory-status-epilepticus
#4
Jun Takei, Ran Takei, Satoshi Nozuma, Keiichi Nakahara, Osamu Watanabe, Hiroshi Takashima
A 40-year-old man presented with a series of generalized tonic-clonic seizures after febrile illness. He developed status epilepticus and required mechanical ventilation with anesthetics. Steroid pulse, intravenous immunoglobulin, and immunoadsorption therapy were administrated, and the status epilepticus improved; however, drug-resistant seizures remained. Despite the use of several antiepileptic drugs, seizures frequently occurred. Additional administration of potassium bromide resulted in significant suppression of seizures...
November 29, 2016: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/27612489/hippocampal-formation-maldevelopment-and-sudden-unexpected-death-across-the-pediatric-age-spectrum
#5
Hannah C Kinney, Annapurna H Poduri, Jane B Cryan, Robin L Haynes, Lisa Teot, Lynn A Sleeper, Ingrid A Holm, Gerald T Berry, Sanjay P Prabhu, Simon K Warfield, Catherine Brownstein, Harry S Abram, Michael Kruer, Walter L Kemp, Beata Hargitai, Joanne Gastrang, Othon J Mena, Elisabeth A Haas, Roya Dastjerdi, Dawna D Armstrong, Richard D Goldstein
Sudden infant death syndrome (SIDS) and sudden unexplained death in childhood (SUDC) are defined as sudden death in a child remaining unexplained despite autopsy and death scene investigation. They are distinguished from each other by age criteria, i.e. with SIDS under 1 year and SUDC over 1 year. Our separate studies of SIDS and SUDC provide evidence of shared hippocampal abnormalities, specifically focal dentate bilamination, a lesion classically associated with temporal lobe epilepsy, across the 2 groups...
September 9, 2016: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/27467370/the-association-between-plasma-ferritin-level-and-simple-febrile-seizures-in-children
#6
Ali O Köksal, Osman Özdemir, Bahar Büyükkaragöz, Merve Karaömerlioglu, Ayse D Bulus
INTRODUCTION: We conducted this study to determine the role of iron deficiency (ID) as a risk factor for simple febrile seizure (SFS) in 6- to 60-month-old children. MATERIALS AND METHODS: In this case-control study 100 children aged 6 to 60 months with febrile seizure (FS) (study group) and 100 febrile children without seizures (control group) admitted to Pediatric Departments of Kecioren Training and Research Hospital in between June 2014 and March 2015 were evaluated...
October 2016: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/27434885/effectiveness-of-electroconvulsive-therapy-for-refractory-status-epilepticus-in-febrile-infection-related-epilepsy-syndrome
#7
Alicia Mirás Veiga, David Conejo Moreno, Ana Isabel Gómez Menéndez, Ignacio Muñoz Siscart, Marta Del Olmo Fernández, Esteban Gómez Sánchez, María García González, Fernando Gómez Sáez
Febrile infection-related epilepsy syndrome (FIRES) is a rare condition which evolves into refractory status epilepticus (SE), with poor outcome in most cases. Conventional antiepileptic drugs fail to control SE in FIRES patients. We report the case of a previously healthy 4-year-old boy who was diagnosed with FIRES. One week after pharyngitis and high fever he started seizures, followed by refractory SE. Benzodiazepines, phenytoin, high-dose barbiturates that induce burst suppression, high doses of corticosteroids, plasmapheresis, immunoglobulins, propofol, lidocaine, ketamine, inhaled desflurane, ketogenic diet, lacosamide, and therapeutic hypothermia were tried at different times in a period of 8 weeks, but all of them were ineffective...
July 19, 2016: Neuropediatrics
https://www.readbyqxmd.com/read/27375752/neurological-manifestations-of-renal-diseases-in-children-in-qazvin-iran
#8
Reza Dalirani, Abolfazl Mahyar, Parviz Ayazi, Ghazaleh Ahmadi
OBJECTIVE: Renal diseases are one of the most common causes of referrals and admissions of children, hence it is important to know their neurological presentations. This study aimed to determine neurological presentations of renal diseases in children. MATERIAL & METHODS: A total of 634 children with renal diseases, admitted to Qazvin Pediatric Hospital, Qazvin, central Iran from 2011 to 2013 were studied. Neurological presentations of patients were established and the results were analyzed using statistical tests...
2016: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/27349086/-abnormal-cerebral-blood-flow-distributions-during-the-post-ictal-phase-of-febrile-status-epilepticus-in-three-pediatric-patients-measured-by-arterial-spin-labeling-perfusion-mri
#9
Keiko Hirano, Tokiko Fukuda
The ability to visualize brain perfusion is important for identifying epileptic foci. We present three pediatric cases showing asymmetrical cerebral blood flow (CBF) distributions during the post-ictal phase of febrile status epilepticus measured by arterial spin labeling (ASL) perfusion MRI. During the acute phase, regional CBF measurements in the areas considered including epileptic foci were higher than in the corresponding area of the contralateral hemisphere, though the exact quantitative value varied between cases...
May 2016: No to Hattatsu. Brain and Development
https://www.readbyqxmd.com/read/27280723/epidemiology-of-pediatric-convulsive-status-epilepticus-with-fever-in-the-emergency-department-a-cohort-study-of-381-consecutive-cases
#10
Itaru Hayakawa, Sahoko Miyama, Nobuaki Inoue, Hiroshi Sakakibara, Hiroshi Hataya, Toshiro Terakawa
Pediatric convulsive status epilepticus with fever is common in the emergency setting but leads to severe neurological sequelae in some patients. To explore the epidemiology of convulsive status epilepticus with fever, a retrospective cohort covering all convulsive status epilepticus cases with fever seen in the emergency department of a tertiary care children's hospital were consecutively collected. Of the 381 consecutive cases gathered, 81.6% were due to prolonged febrile seizure, 6.6% to encephalopathy/encephalitis, 0...
September 2016: Journal of Child Neurology
https://www.readbyqxmd.com/read/27217077/prevalence-of-unique-pediatric-pathologies-encountered-by-paramedic-students-across-age-groups
#11
Eric V Ernest, Tom B Brazelton, Elliot D Carhart, Jonathan R Studnek, Patricia L Tritt, Genghis A Philip, Aaron M Burnett
UNLABELLED: Introduction Traditionally, Emergency Medical Services (EMS) educators have divided the pediatric population into age groups to assist in targeting their clinical and didactic curriculum. Currently, the accrediting body for paramedic training programs requires student exposure to pediatric patients based entirely on age without specifying exposure to specific pathologies within each age stratification. Identifying which pathologies are most common within the different pediatric age groups would allow educators to design curriculum targeting the most prevalent pathologies in each age group and incorporating the physiologic and psychological developmental milestones commonly seen at that age...
August 2016: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/27086496/la-crosse-encephalitis-an-adult-case-series
#12
Amy Lynn A Teleron, Brandon K Rose, David M Williams, Suzanne E Kemper, James E McJunkin
BACKGROUND: La Crosse viral encephalitis is well described in children, but to date, there are only 2 adult cases described in the literature. Despite the fact that pediatric infection can be life threatening and typically presents as a febrile meningoencephalitis often complicated by seizures and mental status changes, little is known about the presentation and course of adult infection. We report the largest case series of adult La Crosse encephalitis. METHODS: Inpatient data were reviewed between 2001 and 2012 to identify adults (≥18 years of age) with possible La Crosse encephalitis...
August 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/27057183/intermittent-diazepam-versus-continuous-phenobarbital-to-prevent-recurrence-of-febrile-seizures-a-randomized-controlled-trial
#13
Mohammadreza Salehiomran, Seyed Mohammad Hoseini, Ali Ghabeli Juibary
OBJECTIVE: Febrile seizure is the most common neurologic problem in children between 3 months to 5 years old. Two to five percent of children aged less than five yr old will experience it at least one time. This type of seizure is age dependent and its recurrence rate is about 33% overalls and 50% in children less than one yr old. The prophylactic treatment is still controversial, so we conducted a randomized controlled clinical trial to find out the effectiveness of continuous phenobarbital versus intermittent diazepam for febrile seizure...
2016: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/26986117/observational-study-of-a-french-and-belgian-multicenter-cohort-of-23-patients-diagnosed-in-adulthood-with-mevalonate-kinase-deficiency
#14
MULTICENTER STUDY
Cécile-Audrey Durel, Achille Aouba, Boris Bienvenu, Samuel Deshayes, Brigitte Coppéré, Bruno Gombert, Cécile Acquaviva-Bourdain, Eric Hachulla, Frédéric Lecomte, Isabelle Touitou, Jacques Ninet, Jean-Baptiste Philit, Laurent Messer, Marc Brouillard, Marie-Hélène Girard-Madoux, Michel Moutschen, Nadia Raison-Peyron, Pascal Hutin, Pierre Duffau, Pierre Trolliet, Pierre-Yves Hatron, Philippe Heudier, Ramiro Cevallos, Thierry Lequerré, Valentine Brousse, Vincent Lesire, Sylvain Audia, Delphine Maucort-Boulch, Laurence Cuisset, Arnaud Hot
The aim of this study was to describe the clinical and biological features of Mevalonate kinase deficiency (MKD) in patients diagnosed in adulthood. This is a French and Belgian observational retrospective study from 2000 to 2014. To constitute the cohort, we cross-check the genetic and biochemical databases. The clinical, enzymatic, and genetic data were gathered from medical records. Twenty-three patients were analyzed. The mean age at diagnosis was 40 years, with a mean age at onset of symptoms of 3 years...
March 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26966048/pharmacotherapy-for-dravet-syndrome
#15
REVIEW
Adam Wallace, Elaine Wirrell, Daniel L Kenney-Jung
Dravet syndrome (DS) is an intractable pediatric epilepsy syndrome, starting in early childhood. This disorder typically manifests with febrile status epilepticus, and progresses to a multifocal epilepsy with febrile and non-febrile seizures with encephalopathy. Most cases are due to a mutation in the SCN1A gene. This article reviews treatments for DS, with an emphasis on pharmacotherapy. While many medications are used in treating the seizures associated with DS, these patients typically have medically refractory epilepsy, and polytherapy is often required...
June 2016: Paediatric Drugs
https://www.readbyqxmd.com/read/26958066/epilepsy-in-children-with-a-history-of-febrile-seizures
#16
Sang Hyun Lee, Jung Hye Byeon, Gun Ha Kim, Baik-Lin Eun, So-Hee Eun
PURPOSE: Febrile seizure, the most common type of pediatric convulsive disorder, is a benign seizure syndrome distinct from epilepsy. However, as epilepsy is also common during childhood, we aimed to identify the prognostic factors that can predict epilepsy in children with febrile seizures. METHODS: The study comprised 249 children at the Korea University Ansan Hospital who presented with febrile seizures. The relationship between the subsequent occurrence of epilepsy and clinical factors including seizure and fever-related variables were analyzed by multivariate analysis...
February 2016: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/26851993/evaluation-of-plasma-melatonin-levels-in-children-with-afebrile-and-febrile-seizures
#17
Orçun Dabak, Demet Altun, Mutluay Arslan, Halil Yaman, Sabahattin Vurucu, Ediz Yesilkaya, Bulent Unay
BACKGROUND: Melatonin modulates central nervous system neuronal activity. We compared the melatonin levels of patients with febrile and afebrile seizures during and after seizure with those of healthy controls. METHODS: We enrolled 59 individuals with afebrile and febrile seizures (mean age, 6.09 ± 4.46 years) and 28 age-, sex-, and weight-matched healthy children. Melatonin levels were measured near the time of a seizure (0 to 1 hour) and at 12 and 24 hours post-seizure, and control melatonin levels were measured from a single venous blood sample...
April 2016: Pediatric Neurology
https://www.readbyqxmd.com/read/26819938/factors-predicting-poor-response-to-initial-therapy-in-benign-childhood-epilepsy-with-centrotemporal-spikes-bcects
#18
Yoon Kyoung Park, So-Hee Eun, Baik-Lin Eun, Jung Hye Byeon
BACKGROUND AND PURPOSE: Benign childhood epilepsy with centrotemporal spikes (BCECTS) is the most common pediatric focal epilepsy syndrome and typically has positive clinical outcomes. However, a few patients experience recurrent seizures, and therefore, require treatment with antiepileptic drugs (AEDs). This study aimed to identify risk factors associated with poor response to initial AED therapy in BCECTS patients. METHODS: We retrospectively reviewed the files of 57 patients who were diagnosed with BCECTS between January 2008 and September 2013...
December 2015: Journal of Epilepsy Research
https://www.readbyqxmd.com/read/26791392/childhood-onset-temporal-lobe-epilepsy-beyond-hippocampal-sclerosis
#19
Angelika Mühlebner, Markus Breu, Gregor Kasprian, Maria T Schmook, Harald Stefanits, Theresa Scholl, Sharon Samueli, Gudrun Gröppel, Anastasia Dressler, Daniela Prayer, Thomas Czech, Johannes A Hainfellner, Martha Feucht
OBJECTIVE: Hippocampal Sclerosis (HS) is widely recognized as a significant underlying cause of drug-resistant temporal lobe epilepsy (TLE) in adults. In contrast, HS is a rare finding in pediatric surgical series, and a higher incidence of HS associated with cortical dysplasia (i.e. FCD type IIIa according to the new ILAE classification) than in adult series has been reported. Data about the electro-clinical characteristics of this subgroup are scarce. METHODS: We studied 15 children and adolescents with drug-resistant TLE and HS who had anterior temporal lobe resection at our center with regard to electroclinical characteristics, MRI features and histopathology...
March 2016: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/26597039/chronological-evolution-of-magnetic-resonance-imaging-findings-in-children-with-febrile-infection-related-epilepsy-syndrome
#20
Marianna S Rivas-Coppola, Namrata Shah, Asim F Choudhri, Robin Morgan, James W Wheless
OBJECTIVE: To describe and analyze the chronological evolution of the radiological findings in seven children with febrile infection-related epilepsy syndrome. METHODS: This is a retrospective study describing the radiological findings and evolution in seven children with febrile infection-related epilepsy syndrome who presented from 2009 to 2013. The children all fit the defined clinical criteria for febrile infection-related epilepsy syndrome; all had a history of normal psychomotor development who presented with acute-onset catastrophic partial status epilepticus associated with a febrile illness or unspecific infectious process...
February 2016: Pediatric Neurology
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