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foveal thickness

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https://www.readbyqxmd.com/read/28650951/development-and-progression-of-a-lamellar-macular-hole-with-lamellar-hole-associated-epiretinal-proliferation
#1
Denise Compera, Matteo G Cereda, Ricarda G Schumann, Ferdinando Bottoni
PURPOSE: To describe evolution and progression of a lamellar macular hole (LMH) with "lamellar hole-associated epiretinal proliferation (LHEP)" using spectral-domain optical coherence tomography and fundus autofluorescence. METHODS: Observational case report. RESULTS: We report on a 63-year-old male patient demonstrating a complete history of LMH development with LHEP occurring during a follow-up period of 8 years. Presenting with a normal foveal contour and attached posterior vitreous at first visit, an LMH developed shortly after incomplete posterior vitreous detachment with vitreopapillary adhesion...
June 23, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28635425/multimodal-imaging-in-cabp4-related-retinopathy
#2
Patrik Schatz, Maram E A Abdalla Elsayed, Arif O Khan
PURPOSE: Multimodal imaging has not been documented for CABP4-related retinopathy. In this study, we describe optical coherence tomography (OCT) and fundus autofluorescence findings for five genetically confirmed cases. METHODS: Retrospective case series. RESULTS: Four patients with the previously described homozygous Saudi CABP4 founder mutation c.81_82insA (p.Pro28ThrfsX44) and one patient with the homozygous mutation c.1A>G (p.Met1?) in CABP4 were examined...
March 1, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/28622270/dexamethasone-intravitreal-implant-for-the-treatment-of-recalcitrant-macular-edema-after-rhegmatogenous-retinal-detachment-repair
#3
Aristomenis Thanos, Bozho Todorich, Yoshihiro Yonekawa, Thanos D Papakostas, Tahsin Khundkar, Dean Eliott, Ashvani B Dass, George A Williams, Antonio Capone, Lisa J Faia, Jeremy D Wolfe, Tarek S Hassan, Alan J Ruby
PURPOSE: To investigate the efficacy of the intravitreal dexamethasone implant as the treatment for recalcitrant macular edema after successful rhegmatogenous retinal detachment repair. METHODS: A retrospective review of the medical records was performed on 17 consecutive patients (17 eyes) with recalcitrant macular edema associated with rhegmatogenous retinal detachment repair who were treated with a single or multiple injections of an intravitreal dexamethasone 0...
June 15, 2017: Retina
https://www.readbyqxmd.com/read/28620652/visual-and-morphologic-outcomes-in-eyes-with-hard-exudate-in-the-comparison-of-age-related-macular-degeneration-treatments-trials
#4
Ebenezer Daniel, Juan E Grunwald, Benjamin J Kim, Maureen G Maguire, Glenn J Jaffe, Cynthia A Toth, Frederick L Ferris, Daniel F Martin, James Shaffer, Gui-Shuang Ying
PURPOSE: To compare baseline characteristics, visual acuity (VA) and morphological outcomes between eyes with baseline hard exudates (HE) and all other eyes among patients with neovascular age-related macular degeneration (NVAMD) treated with anti-vascular endothelial growth factors (anti-VEGF). DESIGN: Prospective cohort study within the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). PARTICIPANTS: Patients with NVAMD...
January 2017: Ophthalmology retina
https://www.readbyqxmd.com/read/28616716/retinal-microstructures-are-altered-in-patients-with-idiopathic-infantile-nystagmus
#5
Jinu Han, Taekjune Lee, Jong Bok Lee, Sueng-Han Han
PURPOSE: To compare segmented retinal layer thicknesses between patients with idiopathic infantile nystagmus (IIN) and controls. METHODS: This retrospective case-control study included 66 patients with IIN and 66 age-matched controls. The retinal layers were examined using spectral domain optical coherence tomography with autosegmentation. Central foveal thickness (CFT), outer nuclear layer (ONL), and outer segment length (OSL) thickness were measured at the fovea center...
June 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28616362/assessing-the-accuracy-of-foveal-avascular-zone-measurements-using-optical-coherence-tomography-angiography-segmentation-and-scaling
#6
Rachel Linderman, Alexander E Salmon, Margaret Strampe, Madia Russillo, Jamil Khan, Joseph Carroll
PURPOSE: The foveal avascular zone (FAZ) is altered in numerous diseases. We assessed factors (axial length, segmentation method, age, sex) impacting FAZ measurements from optical coherence tomography (OCT) angiography images. METHODS: We recruited 116 Caucasian subjects without ocular disease, and acquired two 3 × 3 mm AngioVue scans per each right eye (232 total scans). In images of the superficial plexus, the FAZ was segmented using the AngioVue semiautomatic nonflow measurement tool and ImageJ manual segmentation...
June 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/28613213/ellipsoid-zone-mapping-and-outer-retinal-assessment-in-stargardt-disease
#7
Sruthi Arepalli, Elias I Traboulsi, Justis P Ehlers
PURPOSE: To quantify and correlate ellipsoid zone and photoreceptor outer segment changes with visual acuity in Stargardt disease. METHODS: An institutional review board-approved study of 32 eyes with Stargardt disease was performed. After spectral domain optical coherence tomography, the macular cube was exported into a novel analysis tool and volumetric assessment from the ellipsoid zone to the retinal pigment epithelium was performed. Using this information, mapping was completed with en face representation of the height between the ellipsoid zone and retinal pigment epithelium...
June 6, 2017: Retina
https://www.readbyqxmd.com/read/28610573/correlation-between-short-and-long-term-effects-of-intravitreal-ranibizumab-therapy-on-macular-edema-after-branch-retinal-vein-occlusion-a-prospective-observational-study
#8
Yoshiro Minami, Taiji Nagaoka, Akihiro Ishibazawa, Akitoshi Yoshida
BACKGROUND: The correlation between the short- and long-term effects of intravitreal ranibizumab (IVR) on macular edema after branch retinal vein occlusion (BRVO) remains unclear. We assessed the correlation between the short- and long-term effects of IVR on macular edema after BRVO. METHODS: Twenty-one eyes with macular edema after BRVO were enrolled in this prospective observational study. We measured the foveal thickness (FT) and the best-corrected visual acuity (BCVA) before, 1 day after, and 1 month after IVR (0...
June 13, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28604541/high-dose-high-frequency-aflibercept-for-recalcitrant-neovascular-age-related-macular-degeneration
#9
Qi Sheng You, Raouf Gaber, Amit Meshi, Hema L Ramkumar, Mostafa Alam, Ilkay Kilic Muftuoglu, William R Freeman
PURPOSE: To determine the efficacy of monthly (0.1 mL/4 mg) aflibercept for refractory neovascular age-related macular degeneration (wet age-related macular degeneration). METHODS: This was a retrospective interventional case series in which patients with wet age-related macular degeneration were treated with stepwise dose escalation. Nonvitrectomized patients resistant to monthly (Q4W) ranibizumab/bevacizumab were switched to 2 mg aflibercept every 8 weeks. With resistance, they were escalated to Q4W 2 mg aflibercept, then Q4W 4 mg (high dose high frequency, 4Q4W) aflibercept...
June 9, 2017: Retina
https://www.readbyqxmd.com/read/28603574/central-retinal-vein-occlusion-in-younger-swedish-adults-case-reports-and-review-of-the-literature
#10
Elisabeth Wittström
PURPOSE: To investigate associated systemic diseases, other conditions, visual outcome, ocular complications and treatment in Swedish patients younger than 50 years with central retinal vein occlusion (CRVO) and reviewing the literature. METHODS: Twenty-two patients with CRVO, younger than 50 years, were examined with full-field electroretinography (ERG) within 3 months after a thrombotic event, or were periodically examined and were observed for at least 6 months...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28602014/correlation-between-morphological-changes-and-functional-outcomes-of-recent-onset-macula-off-rhegmatogenous-retinal-detachment-prognostic-factors-in-rhegmatogenous-retinal-detachment
#11
Murat Karacorlu, Isil Sayman Muslubas, Mumin Hocaoglu, Serra Arf, Mehmet Giray Ersoz
PURPOSE: To assess correlation between preoperative and postoperative findings and surgical factors, and postoperative functional outcomes after successful repair of acute macula-off rhegmatogenous retinal detachment (RRD). METHODS: Forty-four eyes of 44 patients with recent-onset macula-off RRD who had primary pars plana vitrectomy were included in this retrospective study. Best-corrected visual acuity (BCVA) and retinal and choroidal changes on spectral-domain optical coherence tomography (SD-OCT) were evaluated before and after surgery...
June 10, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28600301/features-of-optical-coherence-tomography-predictive-of-choroidal-neovascularisation-treatment-response-in-pathological-myopia-in-association-with-fluorescein-angiography
#12
Dong Hyun Lee, Hyun Goo Kang, Sung Chul Lee, Min Kim
BACKGROUND/AIMS: The aim of this study was to evaluate the usefulness of several optical coherence tomography (OCT) findings to estimate choroidal neovascularisation (CNV) activity in pathological myopia using fluorescein angiography (FA) as a reference. METHODS: This was a single-centre, retrospective study. The medical records of patients with active myopic CNV who received intravitreal bevacizumab treatment were reviewed. Parameters to monitor CNV activity were morphological features of CNV on OCT, such as CNV height, central foveal thickness, intraretinal cysts, subretinal fluid, fuzziness of the CNV border, CNV network area on FA, and haemorrhage or exudation on fundus photo...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28600299/evaluation-of-optical-coherence-tomography-angiographic-findings-in-alzheimer-s-type-dementia
#13
Mehmet Bulut, Fatma Kurtuluş, Onursal Gözkaya, Muhammet Kazım Erol, Ayşe Cengiz, Melih Akıdan, Aylin Yaman
BACKGROUND/AIMS: To identify the retinal vascular pathologies in patients with Alzheimer's type dementia (ATD) through optical coherence tomography angiography (OCTA) imaging. METHODS: Our study included 26 patients in the patient group, and age-matched and sex-matched 26 subjects in the control group. A detailed ophthalmological and neurological examination was performed for all subjects included in the study. The retinal, choroidal vascular structures and choroidal thickness (CT) of all subjects were analysed in a detailed way with a commercial spectral domain OCTA...
June 9, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28596917/assessment-of-vascular-change-using-swept-source-optical-coherence-tomography-angiography-a-new-theory-explains-central-visual-loss-in-behcet-s-disease
#14
Thanapong Somkijrungroj, Sritatath Vongkulsiri, Wijak Kongwattananon, Peranut Chotcomwongse, Sasivarin Luangpitakchumpol, Korrawan Jaisuekul
OBJECTIVE: To evaluate retinal vascular structural change in ocular Behcet's using optical coherence tomography angiography (OCTA) and fluorescein angiography (FA). METHODS: An analytic cross-sectional study of 37 eyes of 21 Behcet's uveitic patients was performed. Foveal retinal thickness (FRT), perifoveal hypoperfusion areas in superficial capillary plexus (SCP), and deep capillary plexus (DCP) were measured with swept-source optical coherence tomography and OCTA...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28595625/blood-flow-velocity-and-thickness-of-the-choroid-in-a-patient-with-chorioretinopathy-associated-with-ocular-blunt-trauma
#15
Yuri Ishikawa, Yuki Hashimoto, Wataru Saito, Ryo Ando, Susumu Ishida
BACKGROUND: Choroidal circulation hemodynamics in eyes with ocular blunt trauma has not been quantitatively examined yet. We quantitatively examined changes in choroidal blood flow velocity and thickness at the lesion site using laser speckle flowgraphy (LSFG) and enhanced depth imaging optical coherence tomography (EDI-OCT) in a patient with chorioretinopathy associated with ocular blunt trauma. CASE PRESENTATION: A 13-year-old boy developed a chorioretinal lesion with pigmentation extending from the optic disc to the superotemporal side in the right eye after ocular blunt trauma...
June 8, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28594428/compromised-integrity-of-central-visual-pathways-in-patients-with-macular-degeneration
#16
Maka Malania, Julia Konrad, Herbert Jägle, John S Werner, Mark W Greenlee
Purpose: Macular degeneration (MD) affects the central retina and leads to gradual loss of foveal vision. Although, photoreceptors are primarily affected in MD, the retinal nerve fiber layer (RNFL) and central visual pathways may also be altered subsequent to photoreceptor degeneration. Here we investigate whether retinal damage caused by MD alters microstructural properties of visual pathways using diffusion-weighted magnetic resonance imaging. Methods: Six MD patients and six healthy control subjects participated in the study...
June 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28591282/incidence-of-anterior-segment-neovascularization-during-intravitreal-treatment-for-macular-edema-secondary-to-central-retinal-vein-occlusion
#17
Luiz Filipe Adami Lucatto, Octaviano Magalhães-Junior, Juliana M B Prazeres, Adriano M Ferreira, Ramon A Oliveira, Nilva S Moraes, Flávio E Hirai, Mauricio Maia
Purpose: To analyze the effects of injections of intravitreal triamcinolone acetonide (IVTA) and intravitreal bevacizumab (IVB) on the incidence rates of anterior segment neovascularization (ASN) and neovascular glaucoma (NVG) in patients with macular edema secondary to central retinal vein occlusion (CRVO). Methods: In this prospective, randomized, double-masked, sham-controlled study, 35 patients with macular edema following CRVO were randomized to intravitreal bevacizumab, intravitreal triamcinolone acetonide, or sham injections during the first 6 months of the study...
March 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28590966/characteristics-of-epiretinal-membrane-remnant-edge-by-optical-coherence-tomography-after-pars-plana-vitrectomy
#18
Raouf Gaber, Qi Sheng You, Ilkay Kilic Muftuoglu, Mostafa Alam, Frank F Tsai, Nadia Mendoza, William R Freeman
PURPOSE: To evaluate the incidence, characteristics, and the progression of epiretinal membrane (ERM) remnant edge seen by optical coherence tomography after ERM peeling. METHODS: A retrospective chart review was conducted for 86 eyes of 85 consecutive patients who were diagnosed with ERM and underwent pars plana vitrectomy for epiretinal membrane peeling between 2013 and 2014. Data collected and analyzed included age, gender, preoperative and postoperative visual acuity, use of indocyanine green dye to stain internal limiting membrane, tamponade used after vitrectomy, ERM edge boundaries, presence of cystoid macular edema, and central foveal thickness...
January 11, 2017: Retina
https://www.readbyqxmd.com/read/28590962/longitudinal-changes-in-thicknesses-of-the-macula-ganglion-cell-inner-plexiform-layer-and-retinal-nerve-fiber-layer-after-vitrectomy-a-12-month-observational-study
#19
Hyung-Bin Lim, Min-Woo Lee, Baek-Soo Kwak, Young-Joon Jo, Jung-Yeul Kim
PURPOSE: To analyze longitudinal changes in the thicknesses of the macula, ganglion cell-inner plexiform layer (GC-IPL), and peripapillary retinal nerve fiber layer (RNFL) after vitrectomy. METHODS: Thirty-eight patients diagnosed with intraocular lens (IOL) dislocation without evidence of other vitreoretinal diseases were included. They underwent conventional vitrectomy and IOL transscleral fixation, with a follow-up of 12 months. Using spectral domain optical coherence tomography, the thicknesses of the macula, GC-IPL, and peripapillary RNFL in the vitrectomized and fellow control eyes were measured...
January 23, 2017: Retina
https://www.readbyqxmd.com/read/28574436/qualitative-and-quantitative-assessment-of-vascular-changes-in-diabetic-macular-edema-after-dexamethasone-implant-using-optical-coherence-tomography-angiography
#20
Lisa Toto, Rossella D'Aloisio, Marta Di Nicola, Giuseppe Di Martino, Silvio Di Staso, Marco Ciancaglini, Daniele Tognetto, Leonardo Mastropasqua
The aim of this study was to investigate retinal and choriocapillaris vessel changes in diabetic macular edema (DME) after the intravitreal dexamethasone implant (IDI) using optical coherence tomography angiography (OCTA). Moreover, a comparison between morphological and functional parameters of DME and healthy patients was performed. Twenty-five eyes of 25 type 2 diabetic retinopathy patients complicated by macular edema (DME group) and 25 healthy subjects (control group) were enrolled. Superficial capillary plexus density (SCPD) and deep capillary plexus density (DCPD) in the foveal and parafoveal areas, choricapillary density (CCD) and optic disc vessel density (ODVD) were detected using OCTA at baseline and after 7, 30, 60, 90 and 120 days post injection...
June 2, 2017: International Journal of Molecular Sciences
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