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https://www.readbyqxmd.com/read/29135703/a-case-of-relapsing-retinal-pigment-epithelial-detachment-in-peripapillary-pachychoroid-pigment-epitheliopathy
#1
Fuyan Zhang, Yuxing Qiu, Jay M Stewart
PURPOSE: To report the findings in a patient with peripapillary pachychoroid pigment epitheliopathy who demonstrated a retinal pigment epithelial detachment (PED) that was present at some times but not other times. METHODS: A review of 24 months of the clinical course and findings on multimodal imaging, including color fundus photography, fundus autofluorescence, spectral domain optical coherence tomography, and enhanced depth imaging optical coherence tomography...
November 10, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29135322/retinal-structure-in-pre-clinical-age-related-macular-degeneration
#2
S Nusinowitz, Y Wang, P Kim, S Habib, R Baron, Y Conley, M Gorin
PURPOSE: To determine, if there are identifiable retinal structural changes associated with genetic risk for age-related macular degeneration (AMD). MATERIALS AND METHODS: Seventy-three subjects (range 51.5 to 68.9 years) participated in this prospective study. Subjects were recruited based on the presence of a family history of AMD in one or both parents. All participants underwent a complete ophthalmic exam and imagery for staging of disease severity and genetic testing to assess genetic risk for AMD development...
November 14, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29131901/comparison-of-foveal-macular-and-peripapillary-intraretinal-thicknesses-between-autism-spectrum-disorder-and-neurotypical-subjects
#3
José Javier García-Medina, María García-Piñero, Mónica Del-Río-Vellosillo, Jesarán Fares-Valdivia, Ana Belén Ragel-Hernández, Salvador Martínez-Saura, María Dolores Cárcel-López, Vicente Zanon-Moreno, María Dolores Pinazo-Duran, María Paz Villegas-Pérez
Purpose: To compare thicknesses of intraretinal layers segmented by spectral-domain optical coherence tomography (SD-OCT) between autism spectrum disorder (ASD) and neurotypical (NT) individuals. Methods: We performed 2 scans on 108 eyes from 54 participants (27 high-functioning ASD and 27 age- and sex-matched NT subjects): macular fast volume and peripapillary retinal nerve fiber layer (pRNFL). Macula was automatically segmented. The mean foveal and macular thickness of nine different layers and the thickness of nine pRNFL sectors were considered...
November 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29131474/photodynamic-therapy-with-double-duration-for-circumscribed-choroidal-haemangioma-functional-and-anatomical-results-based-on-initial-parameters
#4
Daniela Süsskind, Werner Inhoffen, Faik Gelisken, Michael Völker
IMPORTANCE: Pretreatment symptoms longer than twelve months and foveal cystoid changes are indicators for poor anatomical and functional outcome after photodynamic therapy. BACKGROUND: To evaluate the prognostic factors on the effectiveness of photodynamic therapy with double duration for treatment of exudative circumscribed choroidal haemangioma DESIGN: Retrospective study. PARTICIPANTS: Twenty-seven patients with symptomatic exudative circumscribed choroidal haemangioma treated with photodynamic therapy...
November 13, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/29117066/predictive-factors-of-surgical-outcomes-in-vitrectomy-for-myopic-traction-maculopathy
#5
Kyoko Hattori, Keiko Kataoka, Jun Takeuchi, Yasuki Ito, Hiroko Terasaki
PURPOSE: To assess predictive factors and surgical outcomes for myopic traction maculopathy. METHODS: This retrospective observational case study enrolled 73 patients who underwent vitrectomy for myopic traction maculopathy. The 79 eyes obtained from our study sample were divided into 4 types: retinoschisis, lamellar macular hole (lamellar MH), foveal retinal detachment (FRD), and FRD + lamellar MH, or into 2 types according to the presence of FRD preoperatively...
November 7, 2017: Retina
https://www.readbyqxmd.com/read/29110126/-lamellar-macular-holes-with-hyporeflective-epiretinal-proliferation-oct-diagnostics-and-clinical-course
#6
REVIEW
D Vogt, F Bottoni, S G Priglinger, R G Schumann
BACKGROUND: High-resolution spectral domain optical coherence tomography (SD-OCT) is the standard examination for assessment of lamellar macular holes (LMH). According to the current SD-OCT classification of LMHs, they are characterized by (1) an irregular foveal contour, (2) a defect in the inner fovea, and (3) a separation of inner retinal layers from outer retinal layers of the fovea leading to an intraretinal splitting with loss of retinal tissue. OBJECTIVE: The article aims to give an overview on the current knowledge of retinal imaging in LMH diagnostics and clinical course of disease...
November 6, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29108397/internal-retinal-layer-thickness-and-macular-migration-after-internal-limiting-membrane-peeling-in-macular-hole-surgery
#7
Mun Y Faria, Nuno P Ferreira, Sofia Mano, Diana M Cristóvao, David C Sousa, Manuel E Monteiro-Grillo
PURPOSE: To provide a spectral-domain optical coherence tomography (SD-OCT)-based analysis of retinal layers thickness and nasal displacement of closed macular hole after internal limiting membrane peeling in macular hole surgery. METHODS: In this nonrandomized prospective interventional study, 36 eyes of 32 patients were subjected to pars plana vitrectomy and 3.5 mm diameter internal limiting membrane (ILM) peeling for idiopathic macular hole (IMH). Nasal and temporal internal retinal layer thickness were assessed with SD-OCT...
October 16, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29103792/foveal-development-in-infants-treated-with-bevacizumab-or-laser-photocoagulation-for-retinopathy-of-prematurity
#8
Ryan N Vogel, Margaret Strampe, Oladipo E Fagbemi, Alexis Visotcky, Sergey Tarima, Joseph Carroll, Deborah M Costakos
PURPOSE: To characterize and quantify early foveal development in preterm infants and to compare this development between eyes treated with intravitreal bevacizumab or laser photocoagulation (LPC) and untreated eyes. DESIGN: Observational case series. PARTICIPANTS: One hundred thirty-one preterm infants undergoing retinopathy of prematurity (ROP) screenings. METHODS: Handheld OCT imaging was performed longitudinally on all patients...
November 2, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29089353/macular-capillary-plexuses-after-epiretinal-membrane-surgery-an-optical-coherence-tomography-angiography-study
#9
Yoon Jeon Kim, Seungmo Kim, Joo Yong Lee, June-Gone Kim, Young Hee Yoon
AIMS: To investigate macular vascular integrity using optical coherence tomography angiography (OCTA) in patients undergoing vitrectomy for idiopathic epiretinal membrane (ERM) removal and to determine its association with structural and visual outcomes. METHODS: Forty-three patients with unilateral ERM who were followed for ≥6 months after surgery were included. Ophthalmological evaluations included best-corrected visual acuity (BCVA) and spectral-domain OCT (SD-OCT) before surgery and 6 months after surgery...
October 31, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29082677/predictive-value-of-baseline-biochemical-parameters-for-clinical-response-of-macular-edema-to-bevacizumab-in-eyes-with-central-retinal-vein-occlusion-a-retrospective-analysis
#10
V G Madanagopalan, Bibha Kumari
PURPOSE: To evaluate the influence of baseline biochemical parameters on the improvement in best corrected visual acuity (BCVA) and reduction in central foveal thickness (CFT) in patients treated with intravitreal bevacizumab (IVB; Avastin, Genentech, Inc) for macular edema (ME) secondary to central retinal vein occlusion (CRVO). DESIGN: A retrospective study. METHODS: Seventy eyes of 70 participants with CRVO who underwent IVB for ME and had at least 1 month of follow-up after the last injection were studied...
October 30, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29079216/macular-morphology-following-unilateral-bevacizumab-injection-for-retinopathy-of-prematurity-an-oct-study
#11
Antony Clark, Tom Wright, Maram Isaac, Carol Westall, Kamiar Mireskandari, Nasrin N Tehrani
This retrospective case series assessed the influence of unilateral intravitreal bevacizumab (IVB) for unilateral type 1 retinopathy of prematurity (ROP) on macular thickness and foveal development. Seven infants with unilateral type 1 ROP were treated with intravitreal bevacizumab 0.625 mg/0.025 ml in one eye only. To determine whether macular thickness and fovea structural development were affected by treatment, spectral domain optical coherence tomography was performed on both treated and untreated eyes...
October 24, 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/29077191/pegaptanib-choroidal-neovascularization-in-patients-with-age-related-macular-degeneration-and-previous-arterial-thromboembolic-events
#12
Maurizio Battaglia Parodi, Emanuele Di Bartolo, Claudia Brue, Ezio Cappello, Claudio Furino, Sebastiano Giuffrida, Manuela Imparato, Michele Reibaldi
PURPOSE: To evaluate the efficacy and the rate of side effects of the pegylated aptamer pegaptanib in the treatment of patients with choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) and a history of previous arterial thromboembolic events (ATEs). METHODS: Twenty-three eyes of 23 patients with subfoveal CNV due to AMD and cerebrovascular accidents (n = 12) and myocardial infarction (n = 11) in the previous 6 months received intravitreal pegaptanib 0...
October 25, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29071469/ultrastructural-analyses-of-internal-limiting-membrane-excised-from-highly-myopic-eyes-with-myopic-traction-maculopathy
#13
Reiji Yokota, Akito Hirakata, Nobutsugu Hayashi, Kazunari Hirota, Tosho Rii, Yuji Itoh, Tadashi Orihara, Makoto Inoue
PURPOSE: To evaluate the ultrastructure of the internal limiting membranes (ILMs) excised during vitrectomy from highly myopic eyes with myopic traction maculopathy (MTM). The clinical findings before and after the vitrectomy were compared. METHODS: Seven eyes of 7 patients with macular retinoschisis were studied. Four of these eyes also had a foveal detachment but without a retinal break. All the eyes underwent vitrectomy with the creation of a posterior vitreous detachment and ILM peeling...
October 25, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29053718/optical-coherence-tomography-angiography-vessel-density-in-children-with-type-1-diabetes
#14
Joanna Gołębiewska, Andrzej Olechowski, Marta Wysocka-Mincewicz, Dominik Odrobina, Marta Baszyńska-Wilk, Artur Groszek, Mieczysław Szalecki, Wojciech Hautz
PURPOSE: To assess the optical coherence tomography angiography (OCTA) retinal vessel density and foveal avascular zone (FAZ) in children with type 1 diabetes (T1D) and compare potential pathologic early changes in this population to healthy age-matched controls. METHODS: This study included 130 pubescent children: 94 with T1D (188 eyes) and 36 of their age-matched control group (60 eyes). OCTA was performed using AngioVue (Avanti, Optivue). FAZ area (mm2) in superficial plexus, whole superficial capillary vessel density (wsVD), fovea superficial vessel density (fsVD), parafovea superficial vessel density (psVD), whole deep vessel density (wdVD), fovea deep vessel density (fdVD), parafovea deep vessel density (pdVD), foveal thickness (FT) (μm) and parafoveal thickness (PFT) (μm) were taken into analysis...
2017: PloS One
https://www.readbyqxmd.com/read/29046877/effect-of-carotenoids-dietary-supplementation-on-macular-function-in-diabetic-patients
#15
Marilita M Moschos, Maria Dettoraki, Michael Tsatsos, George Kitsos, Christos Kalogeropoulos
BACKGROUND: Diabetic retinopathy is a major cause of visual impairment and blindness among working-age people worldwide. The aim of our study was to investigate the effects of a carotenoid supplementation on retinal thickness and macular function of patients with diabetes using optical coherence tomography (OCT) and multifocal electroretinography (mfERG). METHODS: A retrospective study of one hundred and twenty eyes of sixty patients age between 40 and 60 years with non-insulin dependent type 2 diabetes mellitus without diabetic retinopathy who underwent OCT and mfERG and took vitamin supplements for a period of two years...
2017: Eye and Vision (London, England)
https://www.readbyqxmd.com/read/29045946/subfoveal-choroidal-and-macular-thickness-changes-after-phacoemulsification-using-enhanced-depth-imaging-optical-coherence-tomography
#16
Huizhong Jiang, Zhen Li, Ran Sun, Dachuan Liu, Ningpu Liu
PURPOSE: To assess changes in the thickness of the subfoveal retina and choroid after phacoemulsification using enhanced depth imaging optical coherence tomography (EDI-OCT). METHODS: A prospective study was conducted on 100 patients. The subfoveal choroidal thickness (SFCT) was measured at 7 points and the retinal thickness was measured at 5 points (before surgery, and 1 day, 1 week, 1 month, and 3 months after surgery). RESULTS: The foveal choroidal thickness showed a thickening trend (but p > 0...
October 19, 2017: Ophthalmic Research
https://www.readbyqxmd.com/read/29038766/external-validation-of-cut-off-points-for-foveal-thickness-taking-into-account-the-intraretinal-fluid-using-optical-coherence-tomography-to-diagnose-diabetic-macular-oedema
#17
Carmen Hernández-Martínez, Antonio Palazón-Bru, Cesar Azrak, Aída Navarro-Navarro, Manuel Vicente Baeza-Díaz, José Juan Martínez-Toldos, Vicente Francisco Gil-Guillén
BACKGROUND: In late 2015, cut-off points were published for foveal thickness to diagnose diabetic macular oedema taking into account the presence of intraretinal fluid using optical coherence tomography (OCT) in primary care patients (90 µm in the presence of intraretinal fluid and 310 µm otherwise). METHODS: This cross-sectional observational study was carried out on 134 eyes of diabetic patients treated in specialised ophthalmology services in a Spanish region in 2012-2013, to externally validate the aforementioned cut-off points...
2017: PeerJ
https://www.readbyqxmd.com/read/29030692/changes-in-aqueous-concentrations-of-various-cytokines-after-intravitreal-bevacizumab-and-subtenon-triamcinolone-injection-for-diabetic-macular-edema
#18
Seung-Young Yu, Dong Heun Nam, Dae Yeong Lee
PURPOSE: The purpose of this study was to compare the changes in the aqueous cytokine levels after intravitreal bevacizumab with those after combined intravitreal bevacizumab and subtenon triamcinolone injection in diabetic macular edema (DME). METHODS: This study examined 24 eyes of 23 patients with DME. Each patient with DME received randomly either an intravitreal injection of bevacizumab (IVBe) or IVBe with a subtenon triamcinolone injection (IVBe + STTA)...
October 13, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29030589/aberrant-ocular-architecture-and-function-in-patients-with-klinefelter-syndrome
#19
Cristin Brand, Michael Zitzmann, Nicole Eter, Sabine Kliesch, Joachim Wistuba, Maged Alnawaiseh, Peter Heiduschka
Klinefelter Syndrome (KS), the most common chromosomal disorder in men (47,XXY), is associated with numerous comorbidities. Based on a number of isolated case reports, we performed the first systematic and comprehensive evaluation of eye health in KS patients with a focus on ocular structure and vascularization. Twenty-one KS patients and 26 male and 38 female controls underwent a variety of non-invasive examinations investigating ocular morphology (examination of retinal thickness, optic nerve head, and cornea) and function (visual field testing and quantification of ocular vessel density by optical coherence tomography angiography)...
October 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29020667/eye-size-fovea-and-foraging-ecology-in-accipitriform-raptors
#20
Simon Potier, Mindaugas Mitkus, Francesco Bonadonna, Olivier Duriez, Pierre-François Isard, Thomas Dulaurent, Marielle Mentek, Almut Kelber
Birds with larger eyes are predicted to have higher spatial resolution because of their larger retinal image. Raptors are well known for their acute vision, mediated by their deep central fovea. Because foraging strategies may demand specific visual adaptations, eye size and fovea may differ between species with different foraging ecology. We tested whether predators (actively hunting mobile prey) and carrion eaters (eating dead prey) from the order Accipitriformes differ in eye size, foveal depth, and retinal thickness using spectral domain optical coherence tomography and comparative phylogenetic methods...
2017: Brain, Behavior and Evolution
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