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https://www.readbyqxmd.com/read/29145626/twelve-month-outcomes-of-a-group-randomized-community-health-advocate-led-smoking-cessation-intervention-in-public-housing
#1
Daniel R Brooks, Joanna L Burtner, Belinda Borrelli, Timothy C Heeren, Tegan Evans, Jessica A Davine, Jonathan Greenbaum, Matthew Scarpaci, John Kane, Vaughan W Rees, Alan C Geller
Background: Lower rates of smoking cessation are a major reason for the higher prevalence of smoking among socioeconomically disadvantaged adults. Because barriers to quitting are both more numerous and severe, socioeconomically disadvantaged smokers may benefit from more intensive intervention. We sought to determine whether a smoking cessation intervention delivered by public housing residents trained as Tobacco Treatment Advocates (TTAs) could increase utilization of cessation resources and increase abstinence...
November 14, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29145590/who-uses-foodbanks-and-why-exploring-the-impact-of-financial-strain-and-adverse-life-events-on-food-insecurity
#2
E Prayogo, A Chater, S Chapman, M Barker, N Rahmawati, T Waterfall, G Grimble
Background: Rising use of foodbanks highlights food insecurity in the UK. Adverse life events (e.g. unemployment, benefit delays or sanctions) and financial strains are thought to be the drivers of foodbank use. This research aimed to explore who uses foodbanks, and factors associated with increased food insecurity. Methods: We surveyed those seeking help from front line crisis providers from foodbanks (N = 270) and a comparison group from Advice Centres (ACs) (N = 245) in relation to demographics, adverse life events, financial strain and household food security...
November 14, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/29145347/fingertip-winding-suture-pull-out-suture-technique-for-flexor-tendon-repair-in-zone-i
#3
Mostafa Mahmoud, Motaz Elian, Abdalah Seif Elnasr
Injuries to flexor tendons in zone I has always been challenging during repair. Over the time several techniques were developed and modified to achieve the highest repair strength and thus the best functional outcome. These techniques vary from pull-out sutures with internal and external fixation to the use of bone anchors. All techniques were accompanied with advantages and disadvantages as well as postoperative morbidities related to certain techniques. In the present technique we introduce a subperiosteal pull-out suturing technique...
December 2017: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/29144787/lessons-learned-from-a-food-environment-intervention-study-recruitment-and-retention-of-participants-in-disadvantaged-urban-inner-city-neighborhoods
#4
Rachel Engler-Stringer, Joelle Schaefer, Tracy Ridalls, Nazeem Muhajarine
Growing health inequities have led to calls for population health intervention research that can contribute to improving the health of marginalized populations, but conducting research with these communities can be challenging. When research aims to examine and understand an aspect of health in a population characterized as hard-to-reach or marginalized, recruitment techniques appear to have a significant impact on participation and sample retention in longitudinal studies. We examine and comment on the recruitment and retention techniques used in the Good Food, Healthy Families study conducted in low-income, inner-city neighborhoods in a midsized Canadian city; we hope that this will inform recruitment and retention approaches for population health intervention studies in similar populations...
November 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/29144415/the-association-between-environmental-lead-exposure-and-high-school-educational-outcomes-in-four-communities-in-new-south-wales-australia
#5
Jennifer McCrindle, Donna Green, Marianne Sullivan
The associations between environmental lead exposure and high school educational outcomes in four communities located in New South Wales, Australia, were examined in this ecological study. A mixed model analysis was performed to account for each school's results being more similar than results for other schools. The effect of environmental lead exposure on mean results for five educational outcomes was examined. 'Leaded' schools with more than five per cent of students living in the highest lead risk areas were tested against non-leaded 'comparison' schools that were matched by a pre-defined socio-educational advantage rating...
November 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29143970/sample-preparation-for-large-scale-bioanalytical-studies-based-on-liquid-chromatographic-techniques
#6
REVIEW
Andrei Medvedovici, Elena Bacalum, Victor David
Quality of the analytical data obtained for large-scale and long term bioanalytical studies based on liquid chromatography depends on a number of experimental factors including the choice of sample preparation method. This review discusses this tedious part of bioanalytical studies, applied to large scale samples and using liquid chromatography coupled with different detector types as core analytical technique. The main sample preparation methods included in this paper are protein precipitation, liquid-liquid extraction, solid-phase extraction, derivatization, and their versions...
November 16, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/29143897/anaplastic-lymphoma-kinase-testing-ihc-vs-fish-vs-ngs
#7
REVIEW
Xiaomin Niu, Jody C Chuang, Gerald J Berry, Heather A Wakelee
Personalized targeted therapy has emerged as a promising strategy in lung cancer treatment, with current attention focused on elucidation and detection of oncogenic drivers responsible for tumor initiation and maintenance and development of drug resistance. In lung cancer, several oncogenic drivers have been reported, triggering the application of tyrosine kinase inhibitors (TKIs) to target these dysfunctional genes. The anaplastic lymphoma kinase (ALK) rearrangement is responsible for about 4-7% of all non-small cell lung cancers (NSCLCs) and perhaps as high as a third in specific patient populations such as younger, male, non-smokers with advanced stage, epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) wild type, and signet ring cell adenocarcinoma with abundant intracytoplasmic mucin...
November 16, 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/29143689/examination-of-the-susceptibility-gap-in-the-treatment-of-canine-heartworm-infection
#8
REVIEW
Dwight D Bowman, Jason Drake
BACKGROUND: The "susceptibility gap" in a dog diagnosed with adult heartworms has been defined as the period of time in which some Dirofilaria immitis stages are not susceptible to treatment with either macrocyclic lactones or melarsomine dihydrochloride. This was previously defined within the American Heartworm Society guidelines as a period of about 3 months "as per product labels." It can be postulated, however, that a susceptibility gap does not exist with the combination of continued macrocyclic lactone therapy coupled with a three-dose melarsomine dihydrochloride protocol where the first intramuscular treatment is near the time of first diagnosis...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29143547/from-individual-to-global-human-rights-and-aphasia
#9
Deborah Hersh
This commentary marks the 70th anniversary of the Universal Declaration of Human Rights by examining Article 19 and its application to people with aphasia. This group of people still face lack of access, stigmatisation, exclusion, disadvantage and social withdrawal as well as poor public awareness of aphasia and inadequate prioritisation of support and resources. Nevertheless, a range of creative initiatives at individual, healthcare, local community, national and global levels have helped to connect and empower people with aphasia...
November 16, 2017: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29143531/the-population-mean-mood-predicts-the-prevalence-of-depression-in-an-australian-context
#10
Aaron D Sia, Lana J Williams, Julie A Pasco, Felice N Jacka, Sharon L Brennan-Olsen, J Lennert Veerman
BACKGROUND: The mean population mood has been demonstrated to strongly correlate with the prevalence of depression in European populations. Mean population mood has, therefore, been proposed as both a metric to measure the impact of population-level interventions to prevent depression and a target for public health policy. AIM: To demonstrate the relationship between mean population mood and the prevalence of depression using Australian data in order to broaden the applicability of this finding to the Australian population...
November 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/29143237/john-henryism-gender-and-self-reported-health-among-roma-gypsies-in-serbia
#11
Jelena Čvorović, Sherman A James
We describe how self-reported health (SRH) varies with gender and John Henryism (a strong behavioral predisposition to engage in high-effort coping to overcome adversity) in a low income sample of Serbian Roma. Data were collected in 2016 in several Roma settlements around Belgrade, Serbia. The sample consisted of 90 men and 112 women. In addition to John Henryism (JH), measured by a Serbian version of the John Henryism Scale, demographic data and data on SRH and family relationships dynamics were collected...
November 15, 2017: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/29142629/a-prospective-study-with-cage-only-or-cage-with-plate-fixation-in-anterior-cervical-discectomy-and-interbody-fusion-of-one-and-two-levels
#12
Sam Yeol Kim, Seung Hwan Yoon, Dokeun Kim, Chang Hyun Oh, Seyang Oh
Objective: The authors prospectively analyzed the effect of one-level or two-level anterior cervical discectomy and fusion (ACDF), comparing stand-alone cages and cage-with-plate fixation constructs with respect to clinical outcomes and radiologic changes. Methods: A total of 84 patients who underwent one-level (n=52) or two-level ACDF (n=32) for cervical disc disease and who completed 2 years of follow-up were included in this study. The patients were divided by cervical level and grouped into ACDF-Cage-only and ACDF-Cage-with-plate groups...
November 2017: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29142306/an-exome-sequencing-based-approach-for-genome-wide-association-studies-in-the-dog
#13
Bart J G Broeckx, Thomas Derrien, Stéphanie Mottier, Valentin Wucher, Edouard Cadieu, Benoît Hédan, Céline Le Béguec, Nadine Botherel, Kerstin Lindblad-Toh, Jimmy H Saunders, Dieter Deforce, Catherine André, Luc Peelman, Christophe Hitte
Genome-wide association studies (GWAS) are widely used to identify loci associated with phenotypic traits in the domestic dog that has emerged as a model for Mendelian and complex traits. However, a disadvantage of GWAS is that it always requires subsequent fine-mapping or sequencing to pinpoint causal mutations. Here, we performed whole exome sequencing (WES) and canine high-density (cHD) SNP genotyping of 28 dogs from 3 breeds to compare the SNP and linkage disequilibrium characteristics together with the power and mapping precision of exome-guided GWAS (EG-GWAS) versus cHD-based GWAS...
November 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29141634/the-effects-of-neoliberal-policies-on-access-to-healthcare-for-people-with-disabilities
#14
Dikaios Sakellariou, Elena S Rotarou
Neoliberal reforms lead to deep changes in healthcare systems around the world, on account of their emphasis on free market rather than the right to health. People with disabilities can be particularly disadvantaged by such reforms, due to their increased healthcare needs and lower socioeconomic status. In this article, we analyse the impacts of neoliberal reforms on access to healthcare for disabled people. This article is based on a critical analytical review of the literature and on two case studies, Chile and Greece...
November 15, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29141534/characterization-methods-for-solid-lipid-nanoparticles-sln-and-nanostructured-lipid-carriers-nlc
#15
Velichka Andonova, Petya Peneva
BACKGROUND: Solid lipid nanoparticles (SLN) and the next generation of nanostructured lipid carriers (NLC) seem to be a very promising alternative to other colloidal carriers such as liposomes, microemulsions, and polymeric nanoparticles. These combine the advantages of the cited nanocarriers and can improve the dissolution rate in biological fluids, increase the drug absorption, improve the tissue distribution in the target organ, enhance the drug bioavailability and ensure controlled drug release...
November 14, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29140885/john-henryism-coping-and-metabolic-syndrome-among-young-black-adults
#16
Gene H Brody, Tianyi Yu, Gregory E Miller, Katherine B Ehrlich, Edith Chen
OBJECTIVE: To test the novel hypothesis that, among Black Americans who used John Henryism coping, those from low socioeconomic status backgrounds would be more likely to develop metabolic syndrome than would those from higher socioeconomic backgrounds. METHODS: This is an ancillary analysis of SHAPE, a longitudinal cohort of 391 Black youths and their caregivers. From ages 11 to 18 years, family socioeconomic status was assessed. At age 25, John Henryism was assessed, blood samples were drawn, and measurements were taken of blood pressure and waist circumference...
November 15, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/29140858/computerized-cognitive-testing-in-primary-care-a-qualitative-study
#17
Geneva Millett, Gary Naglie, Ross Upshur, Liisa Jaakkimainen, Jocelyn Charles, Mary C Tierney
Computerized cognitive assessment tools may facilitate early identification of dementia in the primary care setting. We investigated primary care physicians' (PCPs') views on advantages and disadvantages of computerized testing based on their experience with the Computer Assessment of Mild Cognitive Impairment (CAMCI). Over a 2-month period, 259 patients, 65 years and older, from the family practice of 13 PCPs completed the CAMCI. Twelve PCPs participated in an individual interview. Generally, PCPs felt that the relationship between them and their patients helped facilitate cognitive testing; however, they thought available paper tests were time consuming and not sufficiently informative...
November 14, 2017: Alzheimer Disease and Associated Disorders
https://www.readbyqxmd.com/read/29140535/socioeconomic-disparities-in-small-for-gestational-age-birth-and-preterm-birth
#18
Tracey Bushnik, Seungmi Yang, Jay S Kaufman, Michael S Kramer, Russell Wilkins
BACKGROUND: Maternal socioeconomic disadvantage has been associated with increased risk of small-for-gestational-age birth and preterm birth. Few studies, however, have considered maternal education and income simultaneously to better understand the mechanisms underlying perinatal health disparities. This analysis examines both maternal education and income and their association with the risk of small-for-gestational-age birth and preterm birth. DATA AND METHODS: The study is based on 127,694 singleton live births from the 2006 Canadian Birth-Census Cohort, a national cohort of births registered from May 2004 to May 2006 that were linked to the 2006 long-form Census...
November 15, 2017: Health Reports
https://www.readbyqxmd.com/read/29138390/estimation-of-ground-pm2-5-concentrations-using-a-dem-assisted-information-diffusion-algorithm-a-case-study-in-china
#19
Lei Ma, Yu Gao, Tengyu Fu, Liang Cheng, Zhenjie Chen, Manchun Li
When estimating national PM2.5 concentrations, the results of traditional interpolation algorithms are unreliable due to a lack of monitoring sites and heterogeneous spatial distributions. PM2.5 spatial distribution is strongly correlated to elevation, and the information diffusion algorithm has been shown to be highly reliable when dealing with sparse data interpolation issues. Therefore, to overcome the disadvantages of traditional algorithms, we proposed a method combining elevation data with the information diffusion algorithm...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29138369/-metabolic-competition-in-tumor-microenvironment
#20
Shingo Eikawa, Heiichiro Udono
Metabolic pathways tightly regulate T cell response in host defense against infection and cancer. Glycolysis plays a key role in effector T cell differentiation and its function. More recent studies have demonstrated that tumor microenvironment forms hypoxia and metabolic disadvantage of immune cells. These environmental attributions impair the effector T cell survival, proliferation and function. Therefore repurposing of metabolic drugs might develop a novel cancer immunotherapy based on the targeting of T cell immunometabolism...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
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