keyword
MENU ▼
Read by QxMD icon Read
search

Nerve fibers layer

keyword
https://www.readbyqxmd.com/read/28728171/optical-coherence-tomography-angiography-of-the-superficial-microvasculature-in-the-macular-and-peripapillary-areas-in-glaucomatous-and-healthy-eyes
#1
Henry Shen-Lih Chen, Chun-Hsiu Liu, Wei-Chi Wu, Hsiao-Jung Tseng, Yung-Sung Lee
Purpose: To quantitatively evaluate the superficial microvasculature in the macular and peripapillary areas in glaucomatous and healthy eyes using optical coherence tomography angiography (OCT-A). Methods: We enrolled 26 eyes of medically managed primary open-angle glaucoma patients and 27 eyes of healthy subjects were enrolled in this prospective study. Measurements of OCT-A vessel density were acquired both in the macular and peripapillary areas. We compared vessel density values, the circumpapillary retinal nerve fiber layer (cpRNFL), the ganglion cell complex (GCC), and standard automated perimetry (SAP) parameters across study groups...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28727882/corneal-confocal-microscopy-an-imaging-endpoint-for-axonal-degeneration-in-multiple-sclerosis
#2
Ioannis N Petropoulos, Saadat Kamran, Yi Li, Adnan Khan, Georgios Ponirakis, Naveed Akhtar, Dirk Deleu, Ashfaq Shuaib, Rayaz A Malik
Purpose: To evaluate whether corneal confocal microscopy (CCM) detects axonal degeneration and whether this is associated with retinal nerve fiber degeneration and clinical disability in patients with multiple sclerosis (MS). Methods: Twenty-five patients with MS and 25 healthy control subjects underwent CCM, optical coherence tomography (OCT), and assessment of neurological disability using the expanded disability status scale (EDSS) and MS severity score (MSSS)...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28727859/space-flight-associated-neuro-ocular-syndrome
#3
Andrew G Lee, Thomas H Mader, C Robert Gibson, William Tarver
New and unique physiologic and pathologic systemic and neuro-ocular responses have been documented in astronauts during and after long-duration space flight. Although the precise cause remains unknown, space flight-associated neuro-ocular syndrome (SANS) has been adopted as an appropriate descriptive term. The Space Medicine Operations Division of the US National Aeronautics and Space Administration (NASA) has documented the variable occurrence of SANS in astronauts returning from long-duration space flight on the International Space Station...
July 20, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28727836/the-disc-damage-likelihood-scale-diagnostic-accuracy-and-correlations-with-cup-to-disc-ratio-structural-tests-and-standard-automated-perimetry
#4
Andrea C Kara-José, Luiz Alberto S Melo, Bruno L B Esporcatte, Angelica T N H Endo, Mauro Toledo Leite, Ivan Maynart Tavares
Our objective was to compare the diagnostic accuracies of and to determine the correlations between the disc damage likelihood scale (DDLS) and anatomical and functional tests used for glaucoma detection. A total of 54 healthy subjects (54 eyes) and 47 primary open-angle glaucoma patients (47 eyes) were included in this cross-sectional observational study. DDLS scores and cup-to-disc (C/D) ratios were evaluated. Subjects underwent standard automated perimetry (SAP), optic disc and retinal nerve fiber layer (RNFL) imaging with time and spectral-domain optical coherence tomography (TD and SD-OCT), Heidelberg Retina Tomograph (HRT II), and scanning laser polarimetry (GDx-VCC)...
2017: PloS One
https://www.readbyqxmd.com/read/28723781/assessment-of-optic-disc-and-ganglion-cell-layer-in-diabetes-mellitus-type-2
#5
Evre Pekel, Gökhan Tufaner, Hüseyin Kaya, Alper Kaşıkçı, Gökhan Deda, Gökhan Pekel
The purpose of this study was to compare the optic disc parameters, retinal nerve fiber (RNFL), and macular ganglion cell layers between patients with diabetes mellitus (DM) type 2 and healthy controls.In this cross-sectional study, 69 eyes of 69 diabetic patients without diabetic retinopathy and 47 eyes of 47 healthy controls were included. Optic disc parameters (i.e., rim area, disc area, cup to disc ratio, cup volume), RNFL, and macular ganglion cell-inner plexiform layers (GCL + IPL) thickness were measured by means of spectral domain optical coherence tomography...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28722174/astrocytes-follow-ganglion-cell-axons-to-establish-an-angiogenic-template-during-retinal-development
#6
Matthew L O'Sullivan, Vanessa M Puñal, Patrick C Kerstein, Joseph A Brzezinski, Tom Glaser, Kevin M Wright, Jeremy N Kay
Immature astrocytes and blood vessels enter the developing mammalian retina at the optic nerve head and migrate peripherally to colonize the entire retinal nerve fiber layer (RNFL). Retinal vascularization is arrested in retinopathy of prematurity (ROP), a major cause of bilateral blindness in children. Despite their importance in normal development and ROP, the factors that control vascularization of the retina remain poorly understood. Because astrocytes form a reticular network that appears to provide a substrate for migrating endothelial cells, they have long been proposed to guide angiogenesis...
July 19, 2017: Glia
https://www.readbyqxmd.com/read/28717659/identification-and-characterization-of-variants-and-a-novel-4%C3%A2-bp-deletion-in-the-regulatory-region-of-six6-a-risk-factor-for-primary-open-angle-glaucoma
#7
Mohd Hussain Shah, Noemi Tabanera, Subbaiah Ramasamy Krishnadas, Manju R Pillai, Paola Bovolenta, Periasamy Sundaresan
BACKGROUND: Primary open-angle glaucoma (POAG) is a complex disease of multigenic inheritance and the most common subtype of glaucoma. SIX6 encodes a transcription factor involved in retina, optic nerve, and pituitary development. Previous studies showed a genetic association between the SIX6 locus and POAG, identifying risk alleles. Whether these alleles are present also in the south Indian population is unclear. METHODS: To address this question, the SIX6 gene and an already characterized and highly conserved SIX6 enhancer (Ch14:60974427-60974430) were sequenced in two south Indian cohorts, respectively, composed of 65/65 and 200/200 POAG cases/age-matched controls...
July 2017: Molecular Genetics & Genomic Medicine
https://www.readbyqxmd.com/read/28717139/relationship-between-retinal-inner-nuclear-layer-thickness-and-severity-of-visual-field-loss-in-glaucoma
#8
Eun Kyoung Kim, Hae-Young Lopilly Park, Chan Kee Park
Glaucoma is a disease characterized by pathologic changes in inner retinal layers, which are comprised of retinal ganglion cells (RGCs). As retinal ganglion cells (RGCs) cross over other retinal neurons that are connected by synapses, it is meaningful to investigate the outer retinal changes in glaucoma. We evaluated the association between thicknesses of segmented retinal layers in macular region and severity of visual field loss in open-angle glaucoma (OAG). This study involved 103 glaucomatous eyes. Retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), and outer nuclear layer (ONL) thicknesses were measured at the macular level using the Spectral-domain optical coherence tomography with segmentation software...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28715584/reduced-retinal-vessel-density-in-obstructive-sleep-apnea-syndrome-patients-an-optical-coherence-tomography-angiography-study
#9
Jian Yu, Kuanlin Xiao, Jingjing Huang, Xinghuai Sun, Chunhui Jiang
Purpose: To examine the retinal vasculature in patients with obstructive sleep apnea-hypopnea syndrome (OSAS) and to determine the correlation between retinal vascularity and the severity of OSAS. Design: Prospective, cross-sectional study. Methods: Sixty-nine consecutive subjects who underwent polysomnography were enrolled. Patients were divided into three groups according to the severity of OSAS, which was defined using the apnea-hypopnea index (AHI) as normal-to-mild (AHI <15), moderate (≥15 to <30), or severe (≥30)...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28706282/retinal-degeneration-in-progressive-supranuclear-palsy-measured-by-optical-coherence-tomography-and-scanning-laser-polarimetry
#10
Birthe Stemplewitz, Robert Kromer, Eik Vettorazzi, Ute Hidding, Andreas Frings, Carsten Buhmann
This cross-sectional study compared the retinal morphology between patients with progressive supranuclear palsy (PSP) and healthy controls. (The retinal nerve fiber layer (RNFL) around the optic disc and the retina in the macular area of 22 PSP patients and 151 controls were investigated by spectral domain optical coherence tomography (SD-OCT). Additionally, the RNFL and the nerve fiber index (NFI) were measured by scanning laser polarimetry (SLP). Results of RNFL measurements with SD-OCT and SLP were compared to assess diagnostic discriminatory power...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28700902/a-novel-algorithm-to-detect-glaucoma-risk-using-texton-and-local-configuration-pattern-features-extracted-from-fundus-images
#11
U Rajendra Acharya, Shreya Bhat, Joel E W Koh, Sulatha V Bhandary, Hojjat Adeli
Glaucoma is an optic neuropathy defined by characteristic damage to the optic nerve and accompanying visual field deficits. Early diagnosis and treatment are critical to prevent irreversible vision loss and ultimate blindness. Current techniques for computer-aided analysis of the optic nerve and retinal nerve fiber layer (RNFL) are expensive and require keen interpretation by trained specialists. Hence, an automated system is highly desirable for a cost-effective and accurate screening for the diagnosis of glaucoma...
June 29, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28699929/arcuate-nerve-fiber-layer-changes-after-internal-limiting-membrane-peeling-in-idiopathic-epiretinal-membrane
#12
Andrea Scupola, Gabriela Grimaldi, Edoardo Abed, Maria G Sammarco, Andrea Giudiceandrea, Andrea Greco, Paola Sasso, Maria A Blasi
PURPOSE: To analyze the relationship between swelling of the arcuate nerve fiber layer (SANFL) and long-term decrease of retinal nerve fiber layer thickness after internal limiting membrane peeling for idiopathic epiretinal membrane, and to investigate if SANFL is related to a mechanical surgical damage. METHODS: Prospective, interventional consecutive case series of 46 eyes that underwent combined epiretinal membrane/internal limiting membrane peeling for idiopathic epiretinal membrane...
July 7, 2017: Retina
https://www.readbyqxmd.com/read/28687846/comparison-of-the-retinal-microvascular-density-between-open-angle-glaucoma-and-nonarteritic-anterior-ischemic-optic-neuropathy
#13
Chun-Hsiu Liu, Wei-Chi Wu, Ming-Hui Sun, Ling-Yuh Kao, Yung-Sung Lee, Henry Shen-Lih Chen
Purpose: To compare optical coherence tomography angiography (OCT-A) retinal vasculature measurements between nonarteritic anterior ischemic optic neuropathy (NAION) and open angle glaucoma (OAG) with altitudinal hemifield visual field defects. Methods: This retrospective cross-sectional study included 10 NAION eyes and 16 OAG eyes, both demonstrating hemifield visual field defects, and 27 normal eyes serving as controls. The peripapillary and macular OCT-A scans were acquired...
July 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28683484/-retinal-nerve-fiber-layer-thickness-measurements-with-optical-coherence-tomography-in-glaucoma-patients-and-healthy-controls
#14
Christian Yahya Mardin
Thickness measurements of the retinal nerve fiber layer in glaucomas have become an important tool for diagnosis and follow-up of progression. High image resolution and advanced evaluation algorithms led to this achievement. In the following OCT anatomy, imaging technique, normative values, monitoring of progression and the influence of artefacts on OCT measurements are matter of discussion. Knowledge of capabilities and pitfalls of RNF imaging with OCT should help to integrate this technique into daily patient routine...
July 6, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28683479/-diagnostic-precision-of-the-confocal-scanning-laser-ophthalmoscopy-in-the-large-optic-disc-with-physiological-excavation-a-long-term-study
#15
Eva Charlotte Koch, Niklas Plange, Matthias Fuest, Hannah Schimitzek, David Kuerten
We repeatedly examined 17 subjects with presumed bilateral physiological excavation labeled as pathological and/or borderline via HRT to verify the diagnosis of physiological cupping or to monitor the long-term progression into normal tension glaucoma. Patients and Methods 17 Subjects with presumed bilateral physiological cupping and large optic discs were included in this long-term follow-up study. All subjects underwent regular detailed ophthalmologic examinations, including intraocular pressure measurement via Goldmann applanation tonometry (GAT), retinal nerve fiber layer imaging via optical coherence tonometry (OCT) and visual field testing and optic disc imaging using the HRT...
July 6, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28678834/normative-database-for-separate-inner-retinal-layers-thickness-using-spectral-domain-optical-coherence-tomography-in-caucasian-population
#16
María Nieves-Moreno, Jose M Martínez-de-la-Casa, Pilar Cifuentes-Canorea, Marina Sastre-Ibáñez, Enrique Santos-Bueso, Federico Sáenz-Francés, Laura Morales-Fernández, Julián García-Feijoó
PURPOSE: Develop the first normative database of the thickness of every inner retinal layer in the macular area in a healthy, Caucasian population between 18 to 87 years old, using Spectralis Optical Coherence Tomography (OCT). METHODS: On this transversal, observational study, 300 patients between 18 to 87 years old and without an ophthalmological condition were recruited. Macular OCT scans were performed on all patients (Spectralis OCT, Heidelberg Engineering)...
2017: PloS One
https://www.readbyqxmd.com/read/28676353/more-sensitive-correlation-of-afferent-pupillary-defect-with-ganglion-cell-complex
#17
Eulogio Besada, Barry J Frauens, Rim Makhlouf, Diana Shechtman, Julie Rodman, Marlon Demeritt, Patrick Hardigan
PURPOSE: This study investigated the correlation between the relative afferent pupillary defect (RAPD) and retinal nerve fiber layer thickness (RNFLT) in optic neuropathy. METHODS: RAPD assessment was performed using a log unit neutral density filter bar. Spectral domain optical coherence tomography RTVue-100 (Optovue) was used to examine the subjects. The optic nerve head pattern (ONH) was subdivided and identified for the purpose of the study into circumpapillary RNFLT (cpRNFLT) and peripheral circumpapillary RNFLT (pcpRNFLT)...
July 1, 2017: Journal of Optometry
https://www.readbyqxmd.com/read/28676313/ganglion-cell-complex-loss-precedes-retinal-nerve-fiber-layer-thinning-in-patients-with-pituitary-adenoma
#18
Yichao Zhang, Zhao Ye, Min Wang, Nidan Qiao
No abstract text is available yet for this article.
July 1, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28676014/citicoline-and-retinal-ganglion-cells-effects-on-morphology-and-function
#19
Vincenzo Parisi, Francesco Oddone, Lucia Ziccardi, Gloria Roberti, Gianluca Coppola, Gianluca Manni
Retinal ganglion cells (RGCs) are the nervous retinal elements that connect the visual receptors to the brain forming the nervous visual system. Functional and/or morphological involvement of RGCs occurs in several ocular and neurological disorders and therefore these cells are targeted in neuroprotective strategies. Cytidine 5-diphosphocholine or Citicoline is an endogenous compound that acts in the biosynthesis of phospholipids of cell membranes and increases neurotransmitters' levels in the Central Nervous System...
July 3, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28671919/evaluation-of-layer-by-layer-segmented-ganglion-cell-complex-thickness-for-detecting-early-glaucoma-according-to-different-macular-grids
#20
Hae Jin Kim, Ki Ho Park, Young Kook Kim, Jin Wook Jeoung
PURPOSE: To investigate the diagnostic performance of layer-by-layer segmented macular ganglion cell complex (GCC) thickness for detecting early glaucoma using spectral-domain optical coherence tomography (SD-OCT) with different macular grids. MATERIALS AND METHODS: Sixty-two early-stage open-angle glaucoma patients and 70 healthy subjects were enrolled in this study. The SD-OCT with automated segmentation was used to obtain macular scans with different grids of "1, 2, and 3 mm"; "1, 2...
June 30, 2017: Journal of Glaucoma
keyword
keyword
118399
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"