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https://www.readbyqxmd.com/read/27908227/improved-infant-hemoglobin-hb-and-blood-glucose-concentrations-the-beneficial-effect-of-maternal-vitamin-a-supplementation-of-malaria-infected-mothers-in-ebonyi-state-nigeria
#1
Michael O Elom, Joseph E Eyo, Fabian C Okafor, Amos Nworie, Victor U Usanga, Gerald N Attamah, Chibueze C Igwe
One hundred and fifty-two malaria-infected pregnant women whose pregnancies had advanced to the 6th month were randomised into two study groups - supplemented and placebo groups, after obtaining their approved consents. Ten thousand international units of vitamin A soft gels were administered to the supplemented group three times per week. Vitamin A soft gels devoid of their active ingredients were administered thrice weekly to the placebo group. Two hundred thousand international units of vitamin A was administered to the supplemented groups within 8 weeks postpartum...
December 1, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27905647/-cleft-lip-palate-and-flour-fortification-with-folic-acid-in-chile
#2
Angélica Paulos, Paulina Pino, Gabriel Cavada, Carolina Lagos, Valentina Broussain, Andrea Hasbún
BACKGROUND: The effect of food fortification with folic acid on the incidence of lip-palate fissures (FLP) is under discussion. AIM: To calculate the rate of hospital discharges due to cleft lip and palate (CLP) and explore whether they decreased after the start of folic acid fortification in Chile. MATERIAL AND METHODS: The hospital discharge databases published by the Chilean Ministry of Health were analyzed. The trends of discharge rates due to CLP of children of less than one year of life (ICD-10 Q350-379 code) and live births (lb) were calculated from 1986 to 2012...
August 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/27905191/race-and-ethnicity-and-preconception-folic-acid-supplement-use-among-pregnant-women-in-georgia-prams-2009-to-2011
#3
Ayesha Mukhtar, Michael R Kramer, Godfrey P Oakley, Vijaya Kancherla
BACKGROUND: The United States Public Health Service recommends that all women of reproductive age consume 400 μg of folic acid daily to prevent major neural tube defects. Hispanics have the highest prevalence of neural tube defects compared with other race/ethnic groups. We studied prevalence of preconception folic acid supplement use, and its association with race/ethnicity among pregnant women in Georgia. METHODS: Using state-wide population-based data from 2009 to 2011 Georgia Pregnancy Risk Assessment Monitoring System, we examined the prevalence of preconception folic acid supplement use among pregnant women aged 18 to 45 years...
December 1, 2016: Birth Defects Research. Part A, Clinical and Molecular Teratology
https://www.readbyqxmd.com/read/27898035/dietary-b-vitamins-and-a-10-year-risk-of-dementia-in-older-persons
#4
Sophie Lefèvre-Arbogast, Catherine Féart, Jean-François Dartigues, Catherine Helmer, Luc Letenneur, Cécilia Samieri
B vitamins may lower the risk of dementia, yet epidemiological findings, mostly from countries with folic acid fortification, have remained inconsistent. We evaluated in a large French cohort of older persons the associations between dietary B vitamins and long-term incident dementia. We included 1321 participants from the Three-City Study who completed a 24 h dietary recall, were free of dementia at the time of diet assessment, and were followed for an average of 7.4 years. In Cox proportional hazards models adjusted for multiple potential confounders, including overall diet quality, higher intake of folate was inversely associated with the risk of dementia (p for trend = 0...
November 26, 2016: Nutrients
https://www.readbyqxmd.com/read/27886045/nutrition-one-carbon-metabolism-and-neural-tube-defects-a-review
#5
REVIEW
Kelei Li, Mark L Wahlqvist, Duo Li
Neural tube defects (NTDs) are a group of severe congenital malformations, induced by the combined effects of genes and the environment. The most valuable finding so far has been the protective effect of folic acid supplementation against NTDs. However, many women do not take folic acid supplements until they are pregnant, which is too late to prevent NTDs effectively. Long-term intake of folic acid-fortified food is a good choice to solve this problem, and mandatory folic acid fortification should be further promoted, especially in Europe, Asia and Africa...
November 23, 2016: Nutrients
https://www.readbyqxmd.com/read/27879392/characterization-of-class-iii-peroxidases-from-switchgrass
#6
Timothy W Moural, Kevin M Lewis, Carlo Barnaba, Fang Zhu, Nathan A Palmer, Gautam Sarath, Erin D Scully, Jeffrey P Jones, Scott E Sattler, ChulHee Kang
Class III peroxidases (CIIIPRX) catalyze the oxidation of monolignols, generate radicals, and ultimately lead to the formation of lignin. In general, CIIIPRX genes encode a large number of isozymes with ranges of in vitro substrate specificities. In order to elucidate the mode of substrate specificity of these enzymes, we characterized one of the CIIIPRXs (PviPRX9) from switchgrass (Panicum virgatum), a strategic plant for 2nd generation biofuels. The crystal structure, kinetic experiments, molecular docking, as well as expression patterns of PviPRX9 across multiple tissues and treatments, along with its levels of coexpression with the majority of genes in the monolignol biosynthesis pathway, revealed the function of PviPRX9 in lignification...
November 15, 2016: Plant Physiology
https://www.readbyqxmd.com/read/27872656/nutritional-situation-among-syrian-refugees-hosted-in-iraq-jordan-and-lebanon-cross-sectional-surveys
#7
S M Moazzem Hossain, Eva Leidman, James Kingori, Abdullah Al Harun, Oleg O Bilukha
BACKGROUND: Ongoing armed conflict in Syria has caused large scale displacement. Approximately half of the population of Syria have been displaced including the millions living as refugees in neighboring countries. We sought to assess the health and nutrition of Syrian refugees affected by the conflict. METHODS: Representative cross-sectional surveys of Syrian refugees were conducted between October 2 and November 30, 2013 in Lebanon, April 12 and May 1, 2014 in Jordan, and May 20 and 31, 2013 in Iraq...
2016: Conflict and Health
https://www.readbyqxmd.com/read/27869705/the-combined-application-of-the-caco-2-cell-bioassay-coupled-with-in-vivo-gallus-gallus-feeding-trial-represents-an-effective-approach-to-predicting-fe-bioavailability-in-humans
#8
REVIEW
Elad Tako, Haim Bar, Raymond P Glahn
Research methods that predict Fe bioavailability for humans can be extremely useful in evaluating food fortification strategies, developing Fe-biofortified enhanced staple food crops and assessing the Fe bioavailability of meal plans that include such crops. In this review, research from four recent poultry (Gallus gallus) feeding trials coupled with in vitro analyses of Fe-biofortified crops will be compared to the parallel human efficacy studies which used the same varieties and harvests of the Fe-biofortified crops...
November 18, 2016: Nutrients
https://www.readbyqxmd.com/read/27846890/safety-and-feasibility-of-cell-based-therapy-of-autologous-bone-marrow-derived-mononuclear-cells-in-plate-stabilized-proximal-humeral-fractures-in-humans
#9
Caroline Seebach, Dirk Henrich, Simon Meier, Christoph Nau, Halvard Bonig, Ingo Marzi
BACKGROUND: Local implantation of ex vivo concentrated, washed and filtrated human bone marrow-derived mononuclear cells (BMC) seeded onto β-tricalciumphosphate (TCP) significantly enhanced bone healing in a preclinical segmental defect model. Based on these results, we evaluated in a first clinical phase-I trial safety and feasibility of augmentation with preoperatively isolated autologous BMC seeded onto β-TCP in combination with angle stable plate fixation for the therapy of proximal humeral fractures as a potential alternative to autologous bone graft from the iliac crest...
November 15, 2016: Journal of Translational Medicine
https://www.readbyqxmd.com/read/27844023/could-folic-acid-influence-growth-cone-motility-during-the-development-of-neural-connectivity
#10
COMMENT
Darrell Wiens
Perinatal dietary supplementation, together with widespread fortification of grain-based foods with synthetic folic acid (FA) has resulted in rising concentrations of unmetabolized plasma FA in pregnant women. In a recently published study we reported on experiments in which we cultured dorsal root ganglia from chick embryos in a range of FA concentrations. We found that FA inhibited neurite extension, synaptogenesis, and growth cone motility. In this commentary we consider the possible mechanism further. The effect of FA is more likely to be on motility processes of growth cones with their exploratory filapodia than on neurotrophic stimulation...
2016: Neurogenesis (Austin, Tex.)
https://www.readbyqxmd.com/read/27827915/dietary-iodine-intake-of-the-australian-population-after-introduction-of-a-mandatory-iodine-fortification-programme
#11
Karen Charlton, Yasmine Probst, Gabriella Kiene
To address mild iodine deficiency in Australia, a mandatory fortification program of iodised salt in bread was implemented in 2009. This study aimed to determine factors associated with achieving an adequate dietary iodine intake in the Australian population post-fortification, and to assess whether bread consumption patterns affect iodine intake in high-risk groups. Using nationally representative data of repeated 24-h dietary recalls from the 2011-2012 Australian National Nutrition and Physical Activity Survey, dietary iodine intakes and food group contributions were compared by age, socioeconomic status (SES), and geographical remoteness (N = 7735)...
November 4, 2016: Nutrients
https://www.readbyqxmd.com/read/27817089/evaluation-of-physicochemical-and-glycaemic-properties-of-commercial-plant-based-milk-substitutes
#12
Stephanie Jeske, Emanuele Zannini, Elke K Arendt
The market for plant-based dairy-type products is growing as consumers replace bovine milk in their diet, for medical reasons or as a lifestyle choice. A screening of 17 different commercial plant-based milk substitutes based on different cereals, nuts and legumes was performed, including the evaluation of physicochemical and glycaemic properties. Half of the analysed samples had low or no protein contents (<0.5 %). Only samples based on soya showed considerable high protein contents, matching the value of cow's milk (3...
November 5, 2016: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/27809707/can-an-educational-intervention-improve-iodine-nutrition-status-in-pregnant-women-a-randomized-controlled-trial
#13
Parisa Amiri, Nadjmeh Hamzavi-Zarghani, Pantea Nazeri, Fazlollah Ghofranipour, Mehrdad Karimi, Atieh Amouzegar, Fereidoun Azizi
BACKGROUND: Pregnant women, due to their increased need for iodine, are among the high risk groups for iodine deficiency. The purpose of this study was to evaluate the effectiveness of an educational program on the iodine nutrition status of pregnant women. METHODS: In This randomized controlled trial, one hundred pregnant women were randomly selected from five health-care centers in southern Tehran, the capital city of Iran. In the intervention group, pregnant women received the educational program lasted four months, and included two face to face educational sessions, using a researcher-designed educational pamphlet in the second and third trimesters and 2 follows-up by telephone calls...
November 3, 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/27808034/iodine-deficiency-in-pregnancy-is-prevalent-in-vulnerable-groups-in-denmark
#14
Ditte Marie Kirkegaard-Klitbo, Kathrine Perslev, Stine Linding Andersen, Hans Perrild, Nils Knudsen, Tom Weber, Lone Banke Rasmussen, Peter Laurberg
INTRODUCTION: Iodine is essential for the production of thyroid hormones. In pregnancy, physiological changes occur that can lead to iodine deficiency and impairment of fetal neurological development. We aimed to assess the iodine intake in pregnant women in Eastern Denmark, compare iodine levels in Eastern and Western Denmark and to identify potentially vulnerable groups. METHODS: This was a cross-sectional cohort study of pregnant Danish women (n = 240). Questionnaires and urine samples were collected at the Ultrasound Clinic, Hvidovre Hospital, Denmark, and urinary iodine concentrations (UIC) (µg/l) were measured...
November 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27801945/metabolic-engineering-of-micronutrients-in-crop-plants
#15
Dieter Blancquaert, Hans De Steur, Xavier Gellynck, Dominique Van Der Straeten
Micronutrient deficiency is a widespread phenomenon, most prevalent in developing countries. Being causally linked to the occurrence of a range of diseases, it affects billions of people worldwide. Enhancing the content of micronutrients in crop products through biotechnology is a promising technique to fight micronutrient malnutrition worldwide. Micronutrient fortification of food products has been implemented in a number of Western countries, but remains inaccessible for poor rural populations in a major part of the developing world...
November 1, 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27801753/effect-of-differential-enteral-protein-on-growth-and-neurodevelopment-in-infants-1500%C3%A2-g-a-randomized-controlled-trial
#16
Shivani Dogra, Anup Thakur, Pankaj Garg, Neelam Kler
OBJECTIVE: To determine if higher enteral protein intake leads to improved head growth at 40 weeks postmenstrual age (PMA) in preterm infants less than 32 weeks or 1500 g. METHOD: Randomized controlled trial in which 120 infants were assigned to either group A with higher enteral protein intake achieved by fortification with higher protein containing fortifier [1 g/100 ml expressed breast milk (EBM)] or to group B with lower enteral protein intake where fortification was done with standard available protein fortifier (0...
October 31, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27790831/strain-improvement-of-pichia-kudriavzevii-ty13-for-raised-phytase-production-and-reduced-phosphate-repression
#17
Linnea Qvirist, Egor Vorontsov, Jenny Veide Vilg, Thomas Andlid
In this work, we present the development and characterization of a strain of Pichia kudriavzevii (TY1322), with highly improved phytate-degrading capacity. The mutant strain TY1322 shows a biomass-specific phytate degradation of 1.26 mmol g(-1)  h(-1) after 8 h of cultivation in a high-phosphate medium, which is about 8 times higher compared with the wild-type strain. Strain TY1322 was able to grow at low pH (pH 2), at high temperature (46°C) and in the presence of ox bile (2% w/v), indicating this strain's ability to survive passage through the gastrointestinal tract...
October 28, 2016: Microbial Biotechnology
https://www.readbyqxmd.com/read/27779826/mystacial-whisker-layout-and-musculature-in-the-guinea-pig-cavia-porcellus-a-social-diurnal-mammal
#18
Robyn A Grant, Mariane G Delaunay, Sebastian Haidarliu
All mammals (apart from apes and humans) have whiskers that make use of a similar muscle arrangement. Whisker specialists, such as rats and mice, tend to be nocturnal and arboreal, relying on their whisker sense of touch to guide exploration around tree canopies at night. As such, nocturnal arboreal rodents have many whiskers that are organised into a grid-like pattern, and moved using a complex array of muscles. Indeed, most arboreal, nocturnal mammals tend to have specialised whiskers that are longer and arranged in a dense, regular grid, compared to terrestrial, diurnal mammals...
October 25, 2016: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/27777705/post-discharge-formula-fortification-of-maternal-human-milk-of-very-low-birth-weight-preterm-infants-an-introduction-of-a-feeding-protocol-in-a-university-hospital
#19
Abeer El Sakka, Mohamed Sami El Shimi, Kareem Salama, Hend Fayez
The objective of this study is to determine the growth parameters and nutritional biochemical markers and complications of fortification of human milk by post discharge formula of preterm very low birth weight newborns (VLBW). Fifty preterm infants less than 37 weeks with weight less than 1500 g were enrolled in the study. They received parental nutrition and feeding according to our protocol. When enteral feeding reached 100 cc/kg/day, infants were randomized into two groups: group I, Cases, n=25, where post discharge formula (PDF) was used for fortification, group II, Controls, n=25 with no fortification...
September 19, 2016: Pediatric Reports
https://www.readbyqxmd.com/read/27777459/gluten-free-starch-noodles-from-sweet-potato-with-reduced-starch-digestibility-and-enhanced-protein-content
#20
Renjusha Menon, G Padmaja, A N Jyothi, V Asha, M S Sajeev
Sweet potato starch (SPS) noodles despite being gluten-free, has low nutritional value as it lacks proteins, minerals, vitamins etc. The objective of this study was to develop gluten-free starch noodles from sweet potato with enhanced protein content through fortification with whey protein concentrate (WPC) and to study the effect of protein fortification and blending SPS with banana (BS), cassava (CS) and mung bean (MBS) starches and annealed cassava starch (ACS) in reducing the starch digestibility. The highest protein retention in cooked noodles was obtained for 20 % WPC fortification, while the lowest starch digestibility was observed for 40 % BS fortified noodles followed by 50 % ACS fortified noodles...
September 2016: Journal of Food Science and Technology
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