keyword
https://read.qxmd.com/read/38536555/folate-induces-stemness-and-increases-oxygen-consumption-under-glucose-deprivation-by-notch-1-pathway-activation-in-colorectal-cancer-cell
#1
JOURNAL ARTICLE
Juan Rodríguez Silva, Matías Monsalves-Álvarez, Carlos Sepúlveda, Camila Donoso-Barraza, Rodrigo Troncoso, Sandra Hirsch
Evidence for folate's protective effects on neural tube defects led the USA and Chile to start mandatory folic acid (FA) fortification programs, decreasing up to 50%. However, ∼30% of the population consuming fortified foods reach supraphysiologic serum levels. Although controversial, several epidemiological and clinical observations suggest that folate increases cancer risk, giving concern about the risks of FA supplementation. The Cancer stem cells (CSCs) model has been used to explain survival to anticancer therapies...
March 27, 2024: Molecular and Cellular Biochemistry
https://read.qxmd.com/read/38535457/new-forms-of-neuroactive-phospholipids-for-dha-enrichment-in-brain
#2
JOURNAL ARTICLE
Romina Gomes, Inês Mendes, Maria Paula Duarte, Narcisa M Bandarra, Ana Gomes-Bispo
Low levels of docosahexaenoic acid (DHA) in the brain have been related to neurological disorders, like Alzheimer's disease (AD). After ingestion, dietary DHA must cross the blood-brain barrier, where it is absorbed as lysophosphatidylcholine (LPC), due to its role as a preferential DHA carrier in the brain. This work aimed at the production of LPC-DHA extracts to be used in supplementation/food fortification intended neural enrichment in DHA. As it is rich in DHA, especially its phospholipids (PL), Atlantic mackerel ( Scomber scombrus , caught in Spring/2022) was used as a raw material...
February 29, 2024: Marine Drugs
https://read.qxmd.com/read/38531295/a-comparative-analysis-of-nutritional-quality-amino-acid-profile-and-nutritional-supplementations-in-plant-based-products-and-their-animal-based-counterparts-in-the-uk
#3
JOURNAL ARTICLE
Liangzi Zhang, Ellie Langlois, Katie Williams, Noemi Tejera, Maja Omieljaniuk, Paul Finglas, Maria H Traka
Plant-based (PB) food products have surged in popularity over the past decade. Available PB products in the UK market were extracted from NielsenIQ Brandbank and compared with animal-based (AB) counterparts in their nutrient contents and calculated Nutri-Scores. The amino acid contents of four beef products and their PB alternatives were analysed by LC-MS/MS. PB products consistently exhibited significantly higher fibre content across all food groups. Protein was significantly higher in AB products from all food groups except beef and ready meals...
March 21, 2024: Food Chemistry
https://read.qxmd.com/read/38529838/new-reference-values-for-thyroid-volume-by-ultrasound-in-german-children-and-adolescents-from-a-population-based-study
#4
JOURNAL ARTICLE
Raphael Hirtz, Roma Thamm, Ronny Kuhnert, Klaus-Peter Liesenkötter, Michael Thamm, Corinna Grasemann
CONTEXT: Reliable reference values for thyroid ultrasound measurements are essential to effectively guide individual diagnostics and direct health care measures at the population level, such as iodine fortification programs. However, the latest reference values for total thyroid volume (Tvol) provided by the WHO in 2004 only apply to the 6 to 12-year-old age group and are limited to countries with a long history of iodine sufficiency, which does not reflect the situation in most European countries, including Germany...
March 26, 2024: Journal of Clinical Endocrinology and Metabolism
https://read.qxmd.com/read/38528412/expression-of-concern-zinc-fortification-and-alleviation-of-cadmium-stress-by-application-of-lysine-chelated-zinc-on-different-varieties-of-wheat-and-rice-in-cadmium-stressed-soil-chemosphere-volume-295-may-2022-133829
#5
JOURNAL ARTICLE
https://read.qxmd.com/read/38518374/advancements-of-the-molecular-directed-design-and-structure-activity-relationship-of-ferritin-nanocage
#6
REVIEW
Xiaoyu Xia, Han Li, Jiachen Zang, Shuzhen Cheng, Ming Du
Ferritin nanocages possess remarkable structural properties and biological functions, making them highly attractive for applications in functional materials and biomedicine. This comprehensive review presents an overview of the molecular characteristics, extraction and identification of ferritin, ferritin receptors, as well as the advancements in the directional design of high-order assemblies of ferritin and the applications based on its unique structural properties. Specifically, this Review focuses on the regulation of ferritin assembly from one to three dimensions, leveraging the symmetry of ferritin and modifications on key interfaces...
March 22, 2024: Journal of Agricultural and Food Chemistry
https://read.qxmd.com/read/38517032/designing-healthier-and-more-sustainable-ultraprocessed-foods
#7
JOURNAL ARTICLE
David Julian McClements
The food industry has been extremely successful in creating a broad range of delicious, affordable, convenient, and safe food and beverage products. However, many of these products are considered to be ultraprocessed foods (UPFs) that contain ingredients and are processed in a manner that may cause adverse health effects. This review article introduces the concept of UPFs and briefly discusses food products that fall into this category, including beverages, baked goods, snacks, confectionary, prepared meals, dressings, sauces, spreads, and processed meat and meat analogs...
March 2024: Comprehensive Reviews in Food Science and Food Safety
https://read.qxmd.com/read/38514019/older-adults-acceptability-of-and-preferences-for-food-based-protein-fortification-in-the-uk-france-and-norway
#8
JOURNAL ARTICLE
Rachel Smith, Lisa Methven, Miriam E Clegg, Alexia Geny, Øydis Ueland, Ida Synnøve Grini, Guro Helgesdotter Rognså, Isabelle Maitre, Céline Brasse, Virginie Van Wymelbeke-Delannoy, Claire Sulmont-Rossé
Research suggests that as we age, protein intake, recognised as vital for combating negative health outcomes, consistently falls below recommendations in older adults. Decreased food intake, combined with age-related eating complications is a major determinant of this protein undernutrition. If nutritional interventions are to be effective and sustainable, they must enable eating pleasure, cater for personal preferences and be adaptable to different eating patterns. As such, we aimed to identify successful strategies for at-home protein-fortification to empower older adults to take a personalised approach to their nutrition, without requiring a large behavioural change...
March 19, 2024: Appetite
https://read.qxmd.com/read/38511974/pediatric-reference-intervals-for-serum-folate-and-cobalamin-based-on-a-european-population-without-exposure-to-folic-acid-fortification
#9
JOURNAL ARTICLE
Peter Ridefelt, Johan Saldeen, Mandy Vogel, Uta Ceglarek, Wieland Kiess, Anders Larsson
The aim of the present study was to define pediatric reference intervals for serum cobalamin and folate utilizing data generated from a population not exposed to food fortified with folic acid. Folate and cobalamin results analyzed by electrochemiluminescence immunoassay (Roche Cobas) were obtained from 2375 children (2 months to 17.99 years of age). The serum samples were collected between 2011 and 2015 as part of the LIFE (Leipzig Research Centre for Civilization Diseases) Child cohort study in Germany, where folic acid fortification of food is not mandated...
March 21, 2024: Scandinavian Journal of Clinical and Laboratory Investigation
https://read.qxmd.com/read/38511617/impact-of-lactiplantibacillus-plantarum-and-casein-fortification-on-angiotensin-converting-enzyme-inhibitory-peptides-in-yogurt-identification-and-in-silico-analysis
#10
JOURNAL ARTICLE
Jiaxu Wang, Zhimin Wang, Mixia Zhang, Jiaxin Li, Cuisong Zhao, Chunli Ma, Dexing Ma
In this study, the effects of Lactiplantibacillus plantarum M11 ( Lb. plantarum M11) in conjunction with sodium caseinate on the characteristics and angiotensin converting enzyme (ACE) inhibitory activity of yogurt were investigated. ACE inhibitory peptides (ACEIPs) in yogurt were identified by nano-LC-MS/MS and potential ACEIPs were predicted by in silico and molecular docking methods. The results showed that the ACE-inhibitory activity of yogurt was significantly enhanced ( p < 0.05), while maintaining the quality characteristics of the yogurt...
March 21, 2024: Food & Function
https://read.qxmd.com/read/38506673/analysis-of-the-current-vitamin-a-terminology-and-dietary-regulations-from-vitamin-a-1-to-vitamin-a-5
#11
Ralph Rühl, Diána Bánáti
<b/>Dietary recommendations on vitamin intake for human food fortification concerning vitamin A in various countries, larger economic zones and international organizations are mainly based on the Food and Agriculture Organization of the United Nations (FAO)/World Health Organization (WHO) "Codex Alimentarius standards". The general vitamin A terminology is based on regulations of the International Union of Pure and Applied Chemistry (IUPAC) that are used to describe the involved derivatives. These regulations and terminology were set up in the middle of the last century...
March 20, 2024: International Journal for Vitamin and Nutrition Research. Journal International de Vitaminologie et de Nutrition
https://read.qxmd.com/read/38498335/genome-wide-identification-of-hmt-gene-family-explores-bphmt2-enhancing-the-selenium-accumulation-and-tolerance-in-broussonetia-papyrifera
#12
JOURNAL ARTICLE
Qiangwen Chen, Changye Zhu, Longfei Guo, Xianchen Bu, Wei Yang, Shuiyuan Cheng, Xin Cong, Feng Xu
Broussonetia papyrifera, a valuable feed resource, is known for its fast growth, wide adaptability, high protein content, and strong selenium enrichment capacity. Selenomethionine (SeMet), the main selenium form in selenium fortification B. papyrifera, is safe for animals and enhances its nutritional value as a feed resource. However, the molecular mechanisms underlying SeMet synthesis remain unclear. This study identified three homocysteine S-methyltransferase genes from B. papyrifera genome. The phylogenetic tree demonstrated that BpHMTs were divided into two classes, and BpHMT2 in the Class 2-D subfamily evolved earlier and possesses more fundamental functions...
March 18, 2024: Tree Physiology
https://read.qxmd.com/read/38490219/feeding-management-and-palate-repair-timing-in-infants-with-cleft-palate-with-and-without-pierre-robin-sequence-a-multisite-study
#13
JOURNAL ARTICLE
Jessica L Williams, Kari M Lien, Richard Kirschner, Gregory Allen, Kathy Chapman
OBJECTIVES: Compare the feeding management practices in infants with cleft palate with and without Pierre Robin sequence (PRS) and determine if specific feeding difficulties or interventions predict delayed palate repair. DESIGN: Retrospective cross-sectional study. SETTING: Seventeen cleft palate teams contributed data. PATIENTS: 414 infants were included in this study: 268 infants with cleft palate only and 146 infants with cleft palate and PRS...
March 15, 2024: Cleft Palate-craniofacial Journal
https://read.qxmd.com/read/38489532/the-use-of-a-novel-donkey-milk-derived-human-milk-fortified-in-the-neonatal-period-had-no-effect-on-the-frequency-of-allergic-manifestations-during-the-first-years-of-life-the-fortilat-trial-follow-up
#14
JOURNAL ARTICLE
Chiara Peila, Elena Spada, Sonia Deantoni, Matteo Borsani, Monica Asteggiano, Federica Chiale, Guido E Moro, Marzia Giribaldi, Laura Cavallarin, Ivan Cortinovis, Alessandra Coscia
Background: Since human milk contents does not meet the high need of very low birth weight infants, fortification of breast milk is a standard practice for this population. As donkey milk has been long considered for children allergic to cow's milk proteins due to its low allergic properties, a new donkey milk-derived fortifier (DF) has been recently evaluated as a valid alternative to bovine milk-derived fortifier (BF). It seems to improve feeding tolerance when compared with standard BF, with similar neurodevelopmental and auxological outcome at 18 months of age...
March 2024: Breastfeeding Medicine
https://read.qxmd.com/read/38488058/comparison-of-growth-outcomes-between-human-milk-fed-preterm-infants-on-standard-versus-adjustable-fortification-protocols
#15
JOURNAL ARTICLE
Meera Khorana, Sareeporn Lamprasertkul, Suppawat Boonkasidecha
Background: Human milk (HM) is usually fortified using standard fortification (STD) to improve nutrition of preterm infants. However, the protein component may still be insufficient. HM could be further fortified with additional protein to improve STD. Objective: The primary objective was to compare changes in body weight (g/day, g/kg/day), length, and head circumference (mm/day) between preterm neonates fed HM with STD and those fed HM with adjustable fortification (ADJ). Methods: This study was a prospective, single-blinded, randomized controlled study in preterm infants of gestational age <32 weeks and weighing ≤1,800 g, admitted to the neonatal unit of the Queen Sirikit National Institute of Child Health...
March 15, 2024: Breastfeeding Medicine
https://read.qxmd.com/read/38474883/risk-of-excess-maternal-folic-acid-supplementation-in-offspring
#16
REVIEW
Xiguang Xu, Ziyu Zhang, Yu Lin, Hehuang Xie
Folate, also known as vitamin B9, facilitates the transfer of methyl groups among molecules, which is crucial for amino acid metabolism and nucleotide synthesis. Adequate maternal folate supplementation has been widely acknowledged for its pivotal role in promoting cell proliferation and preventing neural tube defects. However, in the post-fortification era, there has been a rising concern regarding an excess maternal intake of folic acid (FA), the synthetic form of folate. In this review, we focused on recent advancements in understanding the influence of excess maternal FA intake on offspring...
March 6, 2024: Nutrients
https://read.qxmd.com/read/38474665/vitamin-d-3-bioaccessibility-from-supplements-and-foods-gastric-ph-effect-using-a-static-in-vitro-gastrointestinal-model
#17
JOURNAL ARTICLE
Evangelia Pasidi, Patroklos Vareltzis
Vitamin D3 deficiency is a global phenomenon, which can be managed with supplementation and food fortification. However, vitamin D3 bioaccessibility may depend on factors such as matrix composition and interactions throughout the gastrointestinal (GI) tract. This research focused on the effect of different matrices on vitamin D3 content during digestion, as well as the effect of pH on its bioaccessibility. The INFOGEST protocol was employed to simulate digestion. Three different types of commercial supplements, two foods naturally rich in vitamin D3 , and three fortified foods were investigated...
March 5, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38474613/can-a-fraction-of-flour-and-sugar-be-replaced-with-fruit-by-product-extracts-in-a-gluten-free-and-vegan-cookie-recipe
#18
JOURNAL ARTICLE
Carlotta Breschi, Silvia D'Agostino, Francesco Meneguzzo, Federica Zabini, Jasmine Chini, Luca Lovatti, Luca Tagliavento, Lorenzo Guerrini, Maria Bellumori, Lorenzo Cecchi, Bruno Zanoni
Certain food by-products, including not-good-for-sale apples and pomegranate peels, are rich in bioactive molecules that can be collected and reused in food formulations. Their extracts, rich in pectin and antioxidant compounds, were obtained using hydrodynamic cavitation (HC), a green, efficient, and scalable extraction technique. The extracts were chemically and physically characterized and used in gluten-free and vegan cookie formulations to replace part of the flour and sugar to study whether they can mimic the role of these ingredients...
February 29, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/38464105/arsenic-modifies-the-effect-of-folic-acid-in-spina-bifida-prevention-a-large-hospital-based-case-control-study-in-bangladesh
#19
Chih-Fu Wei, Sudipta Kumar Mukherjee, Sheikh Muhammad Ekramullah, D M Arman, Md Joynul Islam, Mubinul Azim, Asifur Rahman, Md Nafaur Rahman, Md Ziauddin, Gwen Tindula, Hafiza Sultana Suchanda, Diana F Gomberg, Marc G Weisskopf, Liming Liang, Benjamin C Warf, David C Christiani, Maitreyi Mazumdar
Background Spina bifida, a developmental malformation of the spinal cord, is associated with high rates of mortality and disability. Although folic acid-based preventive strategies have been successful in reducing rates of spina bifida, some areas continue to be at higher risk because of chemical exposures. Bangladesh has high arsenic exposures through contaminated drinking water and high rates of spina bifida. Methods We conducted a hospital-based case-control study at the National Institute of Neurosciences & Hospital (NINS&H) in Dhaka, Bangladesh, between December 2016 and December 2022...
February 29, 2024: Research Square
https://read.qxmd.com/read/38462972/micronutrient-deficiency-and-supplements-in-schoolchildren-and-teenagers
#20
JOURNAL ARTICLE
Mette M Berger, Alan Shenkin
PURPOSE OF REVIEW: The essential micronutrients are corner stones in the functional and physical development. Early deficiency has life-long consequences. While awareness about iron deficiency is relatively high, it remains lower for other micronutrients. This review aims at reporting on recent data and attracting attention to the high prevalence of micronutrient deficiencies in school-age and adolescent individuals. RECENT FINDINGS: Iron deficiency anaemia remains highly prevalent worldwide and the most frequent deficiency but can be corrected with simple tools ranging from food fortification, nutritional intervention, and to supplements...
March 11, 2024: Current Opinion in Clinical Nutrition and Metabolic Care
keyword
keyword
118395
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.