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https://www.readbyqxmd.com/read/28224090/vitamin-d-deficiency-insufficiency-from-childhood-to-adulthood-insights-from-a-sunny-country
#1
REVIEW
Motti Haimi, Richard Kremer
Vitamin D is known to be a key regulator of bone metabolism and is associated with muscle strength. Vitamin D deficiency is widely prevalent worldwide. In adults, vitamin D deficiency has been implicated in numerous health conditions including osteoporosis, cancer, diabetes, and autoimmune diseases. Considerable changes have occurred in lifestyles and childhood activities in the past years. Studies have shown that the children population is at high risks of vitamin D deficiency. The objective of this study was to learn about the extent of vitamin D deficiency in children worldwide and especially in sunny country like Israel...
February 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28223994/enhanced-grain-iron-levels-in-rice-expressing-an-iron-regulated-metal-transporter-nicotianamine-synthase-and-ferritin-gene-cassette
#2
Kulaporn Boonyaves, Ting-Ying Wu, Wilhelm Gruissem, Navreet K Bhullar
Micronutrient malnutrition is widespread, especially in poor populations across the globe, and iron deficiency anemia is one of the most prevalent forms of micronutrient deficiencies. Iron deficiency anemia has severe consequences for human health, working ability, and quality of life. Several interventions including iron supplementation and food fortification have been attempted and met with varied degrees of success. Rice, which is a staple food for over half of the world's population, is an important target crop for iron biofortification...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28223907/comparative-bioavailability-and-utilization-of-particular-forms-of-b12-supplements-with-potential-to-mitigate-b12-related-genetic-polymorphisms
#3
REVIEW
Cristiana Paul, David M Brady
CONTEXT: Three natural forms of vitamin B12 are commercially available: methylcobalamin (MeCbl), adenosylcobalamin (AdCbl), and hydroxycobalamin (OHCbl), all of which have been shown in clinical studies to improve vitamin B12 status. They are bioidentical to the B12 forms occurring in human physiology and animal foods. In contrast, cyanocobalamin (CNCbl), a synthetic B12 compound used for food fortification and in some supplements, occurs only in trace amounts in human tissues as a result of cyanide intake from smoking or other sources...
February 2017: Integrative Medicine
https://www.readbyqxmd.com/read/28221977/dietary-exposure-and-natural-occurrence-of-total-aflatoxins-in-basmati-rice-of-pakistan
#4
Nighat Sultana, Iffat Tahira, Mumtaz Kausar, Syed Mujahid Hassan, Nafeesa Qudsia Hanif
This study presents the assessment of total aflatoxins (TAFs) in basmati rice (brown, 1,081; white, 1,170) collected from different areas of Punjab, Pakistan, during 2010 to 2015. Due to the carcinogenicity of TAFs, daily dietary exposure is also evaluated based on rice consumption survey data. Methodology was standardized by matrix spike recoveries at four fortification levels (0.1, 0.5, 2.5, and 12.5 ng/g) for TAFs (aflatoxins B1 [AFB1], B2 [AFB2], G1 [AFG1], and G2 [AFG2]). The present study reveals that 1,750 samples (77...
February 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28220426/measuring-callose-deposition-an-indicator-of-cell-wall-reinforcement-during-bacterial-infection-in-arabidopsis
#5
Lin Jin, David M Mackey
The plant cell wall responds dynamically during interaction with various pathogens. Upon recognition of "nonself" components, plant cells deploy a variety of immune responses including cell wall fortification. Callose, a β-(1, 3)-D-glucan polymer, is a component of the material deposited at the site of infection between the plasma membrane and the preexisting cell wall that is hypothesized to serve as a physical barrier and platform for directed antimicrobial compound deposition. The defense-associated function of callose deposition is supported by its induction during pathogen-associated molecular patterns (PAMP)-triggered immunity (PTI) and its inhibition by defense suppressing virulence effectors...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28219990/an-outbreak-of-pellagra-in-the-kasese-catchment-area-dowa-malawi
#6
George Matapandeu, Samuel H Dunn, Patti Pagels
Pellagra is a deficiency of niacin or its amino acid precursor, tryptophan, which presents with the classic four Ds: the characteristic dermatitis, diarrhea, dementia, and eventually death if left untreated. The incidence of pellagra is quite rare presently because of increased awareness and strategies such as vitamin fortification. However, the deficiency is still present in cultures that rely on maize as their primary source of sustenance. We report a recent outbreak in a catchment area in Kasese, Malawi, of 691 cases of pellagra which were successfully treated with niacin supplementation...
February 20, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28216882/anticancer-potential-of-nutraceutical-formulations-in-mnu-induced-mammary-cancer-in-sprague-dawley-rats
#7
Gummalla Pitchaiah, Annapurna Akula, Vishala Chandi
BACKGROUND: Nutraceuticals help in combating some of the major health problems of the century including cancer, and 'nutraceutical formulations' have led to the new era of medicine and health. OBJECTIVE: To develop different nutraceutical formulations and to assess the anticancer potential of nutraceutical formulations in N-methyl-N-nitrosourea (MNU)-induced mammary cancer in Sprague Dawley rats. MATERIALS AND METHODS: Different nutraceutical formulations were prepared using fine powders of amla, apple, garlic, onion, papaya, turmeric, and wheat grass with and without cow urine distillate...
January 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/28215884/assessing-the-iron-chelation-capacity-of-goat-casein-digest-isolates
#8
A Smialowska, L Matia-Merino, A J Carr
We isolated goat phosphopeptides via calcium and ethanol precipitation from a caseinate digest and investigated their feasibility as an iron-fortification ingredient in nutritional foods. Goat tryptic-digested phosphopeptides could bind 54.37 ± 0.50 mg of Fe/g of protein compared with goat milk, which could bind 3.83 ± 0.01 mg of Fe/g of protein, indicating that isolation did increase iron binding. However, the >13-fold increase in iron binding was only partly explained by the increased concentration of phosphoserine-rich residues in the isolated fraction: we observed a 77% increase in serine residue content and a 5...
February 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28208817/validity-of-the-food-frequency-questionnaire-assessing-the-folate-intake-in-women-of-reproductive-age-living-in-a-country-without-food-fortification-application-of-the-method-of-triads
#9
Milica Zekovic, Marija Djekic-Ivankovic, Marina Nikolic, Mirjana Gurinovic, Dusanka Krajnovic, Marija Glibetic
The study aimed to examine the external validity of the Folate Food Frequency Questionnaire (F-FFQ) designed for assessing the folate intake in Serbian women of reproductive age. The F-FFQ was tested against repeated 24 h dietary recalls and correspondent nutritional biomarkers (red blood cells (RBC) and serum folate concentrations) using the method of triads. In a cross sectional study, 503 women aged 18-49 years completed dietary questionnaires and representative validation subsample (n = 50) provided fasting blood samples for biomarker analyses...
February 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28208798/maternal%C3%A2-folic%C3%A2-acid%C3%A2-supplementation%C3%A2-during%C3%A2-pregnancy%C3%A2-and%C3%A2-childhood%C3%A2-allergic%C3%A2-disease%C3%A2-outcomes-%C3%A2-a%C3%A2-question%C3%A2-of%C3%A2-timing
#10
REVIEW
Catrina L McStay, Susan L Prescott, Carol Bower, Debra J Palmer
Since the early 1990s, maternal folic acid supplementation has been recommended prior  to and during the first trimester of pregnancy, to reduce the risk of infant neural tube defects. In  addition, many countries have also implemented the folic acid fortification of staple foods, in order  to promote sufficient intakes amongst women of a childbearing age, based on concerns surrounding  variable dietary and supplementation practices. As many women continue to take folic acid  supplements beyond the recommended first trimester, there has been an overall increase in folate  intakes, particularly in countries with mandatory fortification...
February 9, 2017: Nutrients
https://www.readbyqxmd.com/read/28192609/effect-of-vitamin-d3-fortification-and-saskatoon-berry-syrup-addition-on-the-flavor-profile-acceptability-and-antioxidant-properties-of-rooibos-tea-aspalathus-linearis
#11
Jennifer Grant, Donna Ryland, Cara K Isaak, Suvira Prashar, Yaw L Siow, Carla G Taylor, Michel Aliani
The unique characteristics and healthful reputation of caffeine-free rooibos tea (RT) make it an ideal carrier for vitamin D3 supplementation, and a potential base for the addition of Saskatoon berry syrup (SBS), a natural flavor additive. The objective of this study was to determine the effect of vitamin D3 fortification and SBS addition on the flavor profile, consumer acceptability, and antioxidant properties of RT. Six formulations (RT, RT with SBS, RT with SBS and vitamin D3 , RT with vitamin D3 , green tea [GT], and GT with SBS) were evaluated by 12 trained panelists and 114 consumers...
February 13, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28185308/medical-cost-savings-in-sakado-city-and-worldwide-achieved-by-preventing-disease-by-folic-acid-fortification
#12
REVIEW
Yasuo Kagawa, Mami Hiraoka, Mitsuyo Kageyama, Yoshiko Kontai, Mayumi Yurimoto, Chiharu Nishijima, Kaori Sakamoto
The introduction of mandatory fortification of grains with folate in 1998 in the United States resulted in 767 fewer spina bifida cases annually and a cost savings of $603 million per year. However, far more significant medical cost savings result from preventing common diseases, including myocardial infarction, stroke, dementia and osteoporosis. A cost-effectiveness analysis showed a gain of 266,649 quality-adjusted life-years and $3.6 billion saved annually, mainly due to the reduction of cardiac infarction...
February 9, 2017: Congenital Anomalies
https://www.readbyqxmd.com/read/28177131/dispersive-liquid-liquid-microextraction-of-quinolones-in-porcine-blood-validation-of-a-ce-method-using-univariate-calibration-or-multivariate-curve-resolution-alternating-least-squares-for-overlapped-peaks
#13
Carla M Teglia, María S Cámara, Luciana Vera-Candioti
In the previously published part of this study, we detailed a novel strategy based on dispersive liquid-liquid microextraction to extract and preconcentrate nine fluoroquinolones in porcine blood. Moreover, we presented the optimized experimental conditions to obtain complete CE separation between target analytes. Consequently, this second part reports the validation of the developed method to determine flumenique, difloxacin, enrofloxacin, marbofloxacin, ofloxacin, ciprofloxacin, through univariate calibration, and enoxacin, danofloxacin, and gatifloxacin through multivariate curve resolution analysis...
February 8, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28174594/preventing-involuntary-admissions-special-needs-for-distinct-patient-groups
#14
Knut Hoffmann, I S Haussleiter, F Illes, J Jendreyschak, A Diehl, B Emons, C Armgart, A Schramm, G Juckel
BACKGROUND: Coercive measures in psychiatry are a controversial topic and raise ethical, legal and clinical issues. Involuntary admission of patients is a long-lasting problem and indicates a problematic pathway to care situations within the community, largely because personal freedom is fundamentally covered by the UN declaration of human rights and the German constitution. METHODS: In this study, a survey on a large and comprehensive population of psychiatric in-patients in the eastern part of North Rhine-Westphalia, Germany, was carried out for the years 2004-2009, including 230...
2017: Annals of General Psychiatry
https://www.readbyqxmd.com/read/28159204/the-use-of-multinutrient-human-milk-fortifiers-in-preterm-infants-a-systematic-review-of-unanswered-questions
#15
REVIEW
Francis B Mimouni, Natalie Nathan, Ekhard E Ziegler, Ronit Lubetzky, Dror Mandel
There is evidence that multinutrient fortification of human milk increases in-hospital growth of preterm infants, but fortification has not been shown to improve long-term growth and neurodevelopmental outcome. We aimed to ascertain whether randomized controlled trials have determined the effect of early versus late introduction of fortifiers on growth and/or other outcomes, and have compared the efficacy/adverse effects of human milk-based versus cow milk-based fortifiers. We conclude that there is little evidence that early introduction of human milk fortification affects important outcomes, and limited evidence that a bovine fortifier places the infant at a higher risk of NEC...
March 2017: Clinics in Perinatology
https://www.readbyqxmd.com/read/28159025/iodine-status-and-thyroid-nodules-in-females-a-comparison-of-cyprus-and-romania
#16
S Gaengler, X D Andrianou, A Piciu, P Charisiadis, C Zira, K Aristidou, D Piciu, K C Makris
OBJECTIVES: The increased comparative prevalence rates of thyroid cancer in Cyprus (>EU average) led us to conduct this study on possible risk factors of thyroid nodules. Romania served as a reference with a comparative thyroid cancer prevalence < EU average. This study aimed to assess the association between urinary iodine (UI) and thyroid nodules in adult females (n = 208) from Cyprus and Romania. STUDY DESIGN: A case-control study (n = 208). METHODS: Cases were females with ultrasound-confirmed thyroid nodules and controls with confirmed absence of nodules...
February 2017: Public Health
https://www.readbyqxmd.com/read/28152548/high-folic-acid-diet-enhances-tumour-growth-in-pymt-induced-breast-cancer
#17
Mariann Fagernæs Hansen, Sarah Østrup Jensen, Ernst-Martin Füchtbauer, Pia M Martensen
BACKGROUND: The B-vitamin folate is among the most studied bioactive food compound, and a dietary intake meeting the daily requirements has been found to reduce the risk of cancer and cardiovascular diseases as well as preventing neural tube defects during fetal development. Several countries have therefore introduced dietary fortification with folic acid. However, clinical and animal studies suggest that folic acid has a dual role in cancer development. METHODS: During the period of initial tumour progression, MMTV-PyMT (MMTV-polyoma virus middle T) transgenic mice were fed with normal diet and high folic acid diet...
February 2, 2017: British Journal of Cancer
https://www.readbyqxmd.com/read/28148687/chemical-composition-but-not-specific-surface-area-affects-calcium-retention-of-nanostructured-calcium-compounds-in-growing-rats
#18
Lidija Posavec, Florentine M Hilty, Jeannine Baumgartner, Hylton Buntting, Monika Hilbe, Marlena Kruger, Frank Krumeich, Anne F Grobler, Michael B Zimmermann
BACKGROUND: Low dietary calcium intake and bioavailability may adversely affect bone health. Reducing the size of calcium compounds increases their specific surface area (SSA, expressed as m(2)/g) and may increase calcium dissolution and bioavailability. OBJECTIVE: We investigated the influence of SSA and chemical composition on the bioavailability of calcium and compared in vitro calcium dissolution with in vivo absorption. METHODS: Calcium dissolution was measured in 0...
February 1, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28139365/vitamin%C3%A2-a-in-pediatrics-an-update-from-the-nutrition-committee-of-the-french-society-of-pediatrics
#19
M Vidailhet, D Rieu, F Feillet, A Bocquet, J-P Chouraqui, D Darmaun, C Dupont, M-L Frelut, J-P Girardet, R Hankard, J-C Rozé, U Siméoni, D Turck, A Briend
Vitamin A (retinol) fulfills multiple functions in vision, cell growth and differentiation, embryogenesis, the maintenance of epithelial barriers and immunity. A large number of enzymes, binding proteins and receptors facilitate its intestinal absorption, hepatic storage, secretion, and distribution to target cells. In addition to the preformed retinol of animal origin, some fruits and vegetables are rich in carotenoids with provitamin A precursors such as β-carotene: 6μg of β-carotene corresponds to 1μg retinol equivalent (RE)...
January 27, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28125098/assessment-of-human-milk-composition-using-mid-infrared-analyzers-requires-calibration-adjustment
#20
R Buffin, E Decullier, V De Halleux, C-M Loys, S Hays, F Studzinsky, E Jourdes, J Rigo, J-C Picaud
OBJECTIVE: Nutrient composition of human milk (HM) is highly variable. Targeted HM fortification has been proposed to address these variations and reduce the cumulative nutritional deficit in preterm infants. Near-infrared analysis is used to measure the protein and fat content in HM; however, the reliability of this technique has not been evaluated. The objective of this study is to evaluate the reproducibility and accuracy of two generations of HM analyzers (HMA1 and HMA2) in estimating protein and lipid contents...
January 26, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
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